Abstract：
:Bone tissue is an anisotropic non-homogeneous composite material composed of inorganic, bone mineral fibres (hydroxyapatite) embedded in an organic matrix (type I collagen and non-collagenous proteins). Factors contributing to the overall mechanical behaviour include constituent volume fraction, mechanical properties, orientation and interfacial bonding interactions. Interfacial bonding between the mineral and organic constituents is based, in part, on electrostatic interactions between negatively charged organic domains and the positively charged mineral surface. Phosphate and fluoride ions have been demonstrated to alter mineral-organic interactions, thereby influencing the mechanical properties of bone in tension. The present study explores the effects of phosphate and fluoride ions on the compressive properties of cortical bone.
journal_name
Biomaterialsjournal_title
Biomaterialsauthors
Walsh WR,Guzelsu Ndoi
10.1016/0142-9612(94)90263-1subject
Has Abstractpub_date
1994-01-01 00:00:00pages
137-45issue
2eissn
0142-9612issn
1878-5905pii
0142-9612(94)90263-1journal_volume
15pub_type
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