Hydrogels in endovascular embolization. V. Antitumour agent methotrexate-containing p(HEMA).

abstract：:Peel bond strength and tensile bond strength between three polyvinylsiloxane denture soft liners and a heat-cured acrylic resin denture base were measured using two adhesive systems. The soft lining materials differed only in regard of their filler content and compliance. The values of bond strength and mode of failur...

journal_title：Biomaterials

authors： McCabe JF,Carrick TE,Kamohara H

更新日期：2002-03-01 00:00:00

abstract：:Wear particle-induced periprosthetic osteolysis has been a clinical problem driving the development of wear resistant ultrahigh molecular weight polyethylene (UHMWPE) for total joint replacement. Radiation crosslinking has been used to decrease wear through decreased plastic deformation; but crosslinking also reduces ...

journal_title：Biomaterials

authors： Oral E,Ghali BW,Rowell SL,Micheli BR,Lozynsky AJ,Muratoglu OK

更新日期：2010-09-01 00:00:00

abstract：:Microspheres of a hydrophobic and a hydrophilic poly(ether-ester) copolymer were evaluated for their in vitro and in vivo biocompatibility and degradation. The microspheres prior to and after sterilization were tested for in vitro cytotoxicity. The in vivo biocompatibility of the poly(ethylene glycol) terephthalate an...

journal_title：Biomaterials

authors： van Dijkhuizen-Radersma R,Hesseling SC,Kaim PE,de Groot K,Bezemer JM

更新日期：2002-12-01 00:00:00

abstract：:Meniscus injuries are prevalent in orthopedic diagnosis. The reconstruction of the structural inhomogeneity and anisotropy of the meniscus is a major challenge in clinical practice. Meniscal tissue engineering has emerged as a potential alternative for the treatment of various meniscal diseases and injuries. In this s...

journal_title：Biomaterials

authors： Chae S,Lee SS,Choi YJ,Hong DH,Gao G,Wang JH,Cho DW

更新日期：2021-01-01 00:00:00

abstract：:Heat treatment of an MgO-CaO-SiO2-P2O5 glass gave a glass ceramic containing crystalline apatite (Ca10(PO4)6O,F2] and beta-wollastonite (CaO,SiO2) in an MgO-CaO-SiO2 glassy matrix. It showed bioactivity and a fairly high mechanical strength which decreased only slowly, even under load-bearing conditions in the body. I...

journal_title：Biomaterials

authors： Kokubo T

更新日期：1991-03-01 00:00:00

abstract：:The magnetic resonance (MR) functionalities of pullulan-conjugated gadolinium diethylene triamine pentaacetate (Gd-DTPA-Pullulan) as a new hepatocyte-specific contrast agent were evaluated. Pullulan, which specifically accumulates on hepatocytes via asialoglycoprotein receptors, was chemically linked with Gd-DTPA. Gd-...

journal_title：Biomaterials

authors： Yim H,Yang SG,Jeon YS,Park IS,Kim M,Lee DH,Bae YH,Na K

更新日期：2011-08-01 00:00:00

abstract：:Multifunctional and water-soluble superparamagnetic iron oxide (SPIO) nanocarriers were developed for targeted drug delivery and positron emission tomography/magnetic resonance imaging (PET/MRI) dual-modality imaging of tumors with integrin α(v)β₃ expression. An anticancer drug was conjugated onto the PEGylated SPIO n...

journal_title：Biomaterials

authors： Yang X,Hong H,Grailer JJ,Rowland IJ,Javadi A,Hurley SA,Xiao Y,Yang Y,Zhang Y,Nickles RJ,Cai W,Steeber DA,Gong S

更新日期：2011-06-01 00:00:00

abstract：:This study examines the early shrinkage behaviour of dental composite resins, and in particular the interfacial stresses around the margins of a composite restoration. The development of stresses at the restoration-tooth interface can have a detrimental effect on the longevity of a restoration. The influence of this i...

journal_title：Biomaterials

authors： Ensaff H,O'Doherty DM,Jacobsen PH

更新日期：2001-12-01 00:00:00

abstract：:Introducing drugs into gene delivery systems to fabricate co-delivery systems for synergy therapy has become a promising strategy for tumor therapy. In this study, a dual responsive co-delivery system RHD/p53 was fabricated to enhance the antitumor efficacy with a low dose of doxorubicin (DOX). The reducible branched ...

journal_title：Biomaterials

authors： Chen S,Lei Q,Li SY,Qin SY,Jia HZ,Cheng YJ,Zhang XZ

更新日期：2016-06-01 00:00:00

abstract：:Osteoclasts resorb bone at surfaces, leaving behind pits and trails where both mineral and organic phases of bone have been dissolved. Rough surface structures are deliberately imparted to synthetic implants, in order to improve osseointegration. The aim of this study is to characterize osteoclastic resorption pits on...

journal_title：Biomaterials

authors： Hefti T,Frischherz M,Spencer ND,Hall H,Schlottig F

更新日期：2010-10-01 00:00:00

abstract：:The role of albumin in the mineralisation process of commercial hydroxyapatite (HAp) and synthesised biphasic (HAp-tricalcium phosphate) ceramics in a bufferless simulated inorganic plasma (HBSS) was investigated by conventional in vitro tests and static and dynamic wettability measurements. Albumin was either pre-ads...

journal_title：Biomaterials

authors： Marques PA,Serro AP,Saramago BJ,Fernandes AC,Magalhães MC,Correia RN

更新日期：2003-02-01 00:00:00

abstract：:We present here an easy method to modify the surface chemistry of polymeric microcapsules of perfluorooctyl bromide used as ultrasound contrast agents (UCAs). Capsules were obtained by a solvent emulsification-evaporation process with phospholipids incorporated in the organic phase before emulsification. Several phosp...

journal_title：Biomaterials

authors： Díaz-López R,Tsapis N,Libong D,Chaminade P,Connan C,Chehimi MM,Berti R,Taulier N,Urbach W,Nicolas V,Fattal E

更新日期：2009-03-01 00:00:00

abstract：:Cytotherapeutic approaches have been investigated to overcome the limitations of existing procedures for periodontal regeneration. In this study, cell sheet transplantation was performed using three kinds of mesenchymal tissue (periodontal ligament, alveolar periosteum, and bone marrow)-derived cells to compare the di...

journal_title：Biomaterials

authors： Tsumanuma Y,Iwata T,Washio K,Yoshida T,Yamada A,Takagi R,Ohno T,Lin K,Yamato M,Ishikawa I,Okano T,Izumi Y

更新日期：2011-09-01 00:00:00

abstract：:A major role of respiratory mucus is to trap inhaled particles, including pathogens and environmental particulates, to limit body exposure. Despite the tremendous health implications, how particle size and surface chemistry affect mobility in respiratory mucus from humans without lung disease is not known. We prepared...

journal_title：Biomaterials

authors： Schuster BS,Suk JS,Woodworth GF,Hanes J

更新日期：2013-04-01 00:00:00

abstract：:Surface plasmon resonance (SPR) sensing has long been used to study biomolecular binding events and their kinetics in a label-free way. This approach has recently been extended to SPR microscopy, which is an ideal tool for probing large microarrays of biomolecules for their binding interactions with various partners a...

journal_title：Biomaterials

authors： Campbell CT,Kim G

更新日期：2007-05-01 00:00:00

abstract：:Helicobacter pylori (H. pylori) infection is highly prevalent, and has a strong association with various gastric diseases, including gastritis, digestive ulcers, and cancer. H. pylori strains with resistance to existing antibiotics have emerged in the past two decades. Currently, treatment of H. pylori infection (invo...

journal_title：Biomaterials

authors： Narayana JL,Huang HN,Wu CJ,Chen JY

更新日期：2015-08-01 00:00:00

abstract：:Concerns over disease transmission, high costs and limited supply have led to interest in synthetic grafts in the field of impaction bone grafting (IBG). Poly(DL-lactic acid) (PLA) grafts are attractive alternatives due to their biocompatibility, established safety and versatile manufacturing process. This study exami...

journal_title：Biomaterials

authors： Bolland BJ,Kanczler JM,Ginty PJ,Howdle SM,Shakesheff KM,Dunlop DG,Oreffo RO

更新日期：2008-08-01 00:00:00

abstract：:Bone tissue is an anisotropic non-homogeneous composite material composed of inorganic, bone mineral fibres (hydroxyapatite) embedded in an organic matrix (type I collagen and non-collagenous proteins). Factors contributing to the overall mechanical behaviour include constituent volume fraction, mechanical properties,...

journal_title：Biomaterials

authors： Walsh WR,Guzelsu N

更新日期：1994-01-01 00:00:00

abstract：:In the design of parenteral delivery systems the modulation of the biodegradation of a polymer matrix represents a promising strategy to control drug release. We have investigated the degradation of ABA triblock copolymers, consisting of poly(lactide-co-glycolide) A-blocks and poly(oxyethylene) B-blocks, and PLG, poly...

journal_title：Biomaterials

authors： Witt C,Mäder K,Kissel T

更新日期：2000-05-01 00:00:00

abstract：:This study examined the engineering and true axial stress-strain behavior of smooth cylindrical and shallow and deep notched cylindrical test specimens, under applied axial tensile loading using non-contacting methods, of both conventional and highly crosslinked ultra-high molecular weight polyethylenes (UHMWPEs). The...

journal_title：Biomaterials

authors： Sobieraj MC,Kurtz SM,Rimnac CM

更新日期：2005-06-01 00:00:00

abstract：:Targeted drug delivery with precisely controlled drug release and activation is highly demanding and challenging for tumor precision therapy. Herein, a biomimetic cascade nanoreactor (designated as Mem@GOx@ZIF-8@BDOX) is constructed for tumor targeted starvation therapy-amplified chemotherapy by assembling tumor cell ...

journal_title：Biomaterials

authors： Cheng H,Jiang XY,Zheng RR,Zuo SJ,Zhao LP,Fan GL,Xie BR,Yu XY,Li SY,Zhang XZ

更新日期：2019-03-01 00:00:00

abstract：:Polysaccharides are increasingly being used as biomaterials for tissue engineering and regenerative medicine. Quantitative analysis of gene expression from cells in three-dimensional (3D) scaffolds requires extraction of messenger RNA, which is complicated in polysaccharide materials by ionic complexing between nuclei...

journal_title：Biomaterials

authors： Wang L,Stegemann JP

更新日期：2010-03-01 00:00:00

abstract：:Decellularization techniques have been widely used as an alternative strategy for organ reconstruction. However, the compliance of tracheal or laryngeal tissues can be increased during the decellularization process, which might cause postoperative stenosis due to elimination of chondrocytes. The purpose of our study w...

journal_title：Biomaterials

authors： Ma R,Li M,Luo J,Yu H,Sun Y,Cheng S,Cui P

更新日期：2013-02-01 00:00:00

abstract：:Osteoinductive biomaterials are promising for bone repair. There is no direct proof that bone marrow mesenchymal stem cells (BMSCs) home to non-osseous sites and participate in ectopic bone formation induced by osteoinductive bioceramics. The objective of this study was to use a sex-mismatched beagle dog model to inve...

journal_title：Biomaterials

authors： Song G,Habibovic P,Bao C,Hu J,van Blitterswijk CA,Yuan H,Chen W,Xu HH

更新日期：2013-03-01 00:00:00

abstract：:In order to investigate the effects of different degrees of bioactivity of xerogels on connexin 43 (cx43) signaling of osteoclasts a cell culture approach was developed. Cells isolated from peripheral blood mononuclear cells were cultured in combination with the xerogels and were harvested for further investigations o...

journal_title：Biomaterials

authors： Glenske K,Wagner AS,Hanke T,Cavalcanti-Adam EA,Heinemann S,Heinemann C,Kruppke B,Arnhold S,Moritz A,Schwab EH,Worch H,Wenisch S

更新日期：2014-02-01 00:00:00

abstract：:The clinical usefulness of brain machine interfaces that employ penetrating silicon microelectrode arrays is limited by inconsistent performance at chronic time points. While it is widely believed that elements of the foreign body response (FBR) contribute to inconsistent single unit recording performance, the relatio...

journal_title：Biomaterials

authors： Nolta NF,Christensen MB,Crane PD,Skousen JL,Tresco PA

更新日期：2015-01-01 00:00:00

abstract：:Dibutyryl chitin (DBC) is a modified chitin carrying butyryl groups at 3 and 6 positions; its peculiarity is that it dissolves promptly in common solvents, while being insoluble in aqueous systems. The high biocompatibility of dibutyryl chitin in the form of films and non-wovens has been demonstrated for human, chick ...

journal_title：Biomaterials

authors： Muzzarelli RA,Guerrieri M,Goteri G,Muzzarelli C,Armeni T,Ghiselli R,Cornelissen M

更新日期：2005-10-01 00:00:00

abstract：:A series of supramolecular pseudo-block polycations (CD-SS-pDM/Ad-pPEGs) were realized by assembling bioreducible β-cyclodextrin-cored star poly (2-dimethyl amino)ethyl methacrylate with different molecular weight and an adamantine-ended linear poly(poly(ethylene glycol)ethyl ether methacrylate) (pPEGEEMA) via the hos...

journal_title：Biomaterials

authors： Hu Y,Yuan W,Zhao NN,Ma J,Yang WT,Xu FJ

更新日期：2013-07-01 00:00:00

abstract：:Gd3+-based contrast agents monopolize in the clinical MR imaging-based diagnosis of hepatic tumors, however, the inherent toxicity by the released Gd3+-ions triggered an urgent demand for safer alternatives. Here, we demonstrate hollow manganese silicate nanoparticles (HMS), which exert burst-release of Mn2+-ions by s...

journal_title：Biomaterials

authors： Kim JG,Jang MS,Kumari N,Choi JK,Im GH,Kwon T,Lee JH,Lee WJ,Lee IS

更新日期：2020-02-01 00:00:00

abstract：:Permanent male sterilization has been recognized as useful tools for the development of neuter experimental animals and fattening livestock, as well as efficient control of pet overpopulation. Traditional routes such as surgical ways, chemical injections, and anti-fertility vaccines have addressed these crucial proble...

journal_title：Biomaterials

authors： Liu Z,Liu X,Ran X,Ju E,Ren J,Qu X

更新日期：2015-11-01 00:00:00