Notch strengthening and hardening behavior of conventional and highly crosslinked UHMWPE under applied tensile loading.

abstract：:The purpose of this study is to analyze the roles of two non-invasive techniques, bone scintigraphy and resonance frequency analysis (RFA), in the osseointegration assessment. Sixty implants with sandblasted/acid-etched (SA) or machined (MA) surface were placed into the distal femur condyles of 30 rabbits. At 1, 2, 4,...

journal_title：Biomaterials

authors： Zhou Y,Jiang T,Qian M,Zhang X,Wang J,Shi B,Xia H,Cheng X,Wang Y

更新日期：2008-02-01 00:00:00

abstract：:The interactions between alginate and polycations have been studied by using different labelling techniques. Binding of poly-L-lysine (PLL) to alginate in the gel state is mainly governed by the amount of dissociable negative charges on the bead surface. PLL was found to bind more rapidly to gel beads made from algina...

journal_title：Biomaterials

authors： Thu B,Bruheim P,Espevik T,Smidsrød O,Soon-Shiong P,Skjåk-Braek G

更新日期：1996-05-01 00:00:00

abstract：:Lipoproteins are a family of plasma nanoparticles responsible for the transportation of lipids throughout the body. High-density lipoprotein (HDL), the smallest of the lipoprotein family, measures 7-13 nm in diameter and consists of a cholesteryl ester and triglyceride core that is covered with a monolayer of phosphol...

journal_title：Biomaterials

authors： Skajaa T,Cormode DP,Jarzyna PA,Delshad A,Blachford C,Barazza A,Fisher EA,Gordon RE,Fayad ZA,Mulder WJ

更新日期：2011-01-01 00:00:00

abstract：:Long-term (8 and 24 month) reactions of the (hypo) dermis of the guinea pig to solid and porous (50 vol%) acrylic implants and four human biopsies from porous subcutaneous acrylic implants were studied light microscopically. The solid implants were encapsulated by dense connective tissue. Mobility was evidenced by the...

journal_title：Biomaterials

authors： van Mullem PJ,Vaandrager JM,Nicolai JP,de Wijn JR

更新日期：1990-07-01 00:00:00

abstract：:Islet transplantation is a method for the treatment of type 1 diabetes mellitus (DM) and has been widely performed around the world. The long-term cryopreservation of islets shows many advantages in the field of islet transplantation. Previous studies have described the development of sheet-type polyvinyl alcohol (PVA...

journal_title：Biomaterials

authors： Qi Z,Shen Y,Yanai G,Yang K,Shirouzu Y,Hiura A,Sumi S

更新日期：2010-05-01 00:00:00

abstract：:Angiogenesis is a complex multistage process involving multiple factors and numerous cells. The use of the Chorioallantoic Membrane (CAM) assay is well documented as a method to investigate angiogenesis. This technique is ideal for screening samples, but requires an objective analysis technique. The angiogenic respons...

journal_title：Biomaterials

authors： Oates M,Chen R,Duncan M,Hunt JA

更新日期：2007-09-01 00:00:00

abstract：:Neonates with congenital diaphragmatic hernia often require surgical defect closure with a patch. Alternatives to native diaphragmatic tissue are critically needed for this paediatric surgery. The clinical efficacy of mesh patches is limited by complications associated with residual foreign material and by hernia recu...

journal_title：Biomaterials

authors： Zhang XY,Yanagi Y,Sheng Z,Nagata K,Nakayama K,Taguchi T

更新日期：2018-06-01 00:00:00

abstract：:It has been demonstrated that using cultured chondrocytes that have been seeded onto various biomatrices can enhance the quality of the articular cartilage repair tissue. As tissue-engineering becomes increasingly more complex there is a need to understand how a specific biomaterial may influence gene expression. In t...

journal_title：Biomaterials

authors： Saldanha V,Grande DA

更新日期：2000-12-01 00:00:00

abstract：:Biodegradable and pH-sensitive hydrogels containing azoaromatic moieties were synthesized from the same polymeric precursors by two synthetic methods, namely a polymer-polymer reaction and cross-linking of polymeric precursors. The effect of the synthetic route employed and the detailed network structure on in vitro d...

journal_title：Biomaterials

authors： Ghandehari H,Kopecková P,Kopecek J

更新日期：1997-06-01 00:00:00

abstract：:Controlling cell orientation and morphology through topographical patterning is a phenomenon that is applicable to a wide variety of medical applications such as implants and tissue engineering scaffolds. Previous work in this field, termed contact guidance, has demonstrated the application of this cellular response o...

journal_title：Biomaterials

authors： Bettinger CJ,Orrick B,Misra A,Langer R,Borenstein JT

更新日期：2006-04-01 00:00:00

abstract：:The aim of this study was to evaluate the physical-chemical properties, in vivo biocompatibility and antimicrobial activity of bioactive glasses (BG) used as a controlled release device for tetracycline hydrochloride and an inclusion complex formed by tetracycline and beta-cyclodextrin at 1:1 molar ratio. The BG as we...

journal_title：Biomaterials

authors： Domingues ZR,Cortés ME,Gomes TA,Diniz HF,Freitas CS,Gomes JB,Faria AM,Sinisterra RD

更新日期：2004-01-01 00:00:00

abstract：:The development of topical microbicides is a valid approach to protect the genital mucosa from sexually transmitted infections that cannot be contained with effective vaccination, like HSV and HIV infections. A suitable target of microbicides is the interaction between viral proteins and cell surface heparan sulfate p...

journal_title：Biomaterials

authors： Donalisio M,Quaranta P,Chiuppesi F,Pistello M,Cagno V,Cavalli R,Volante M,Bugatti A,Rusnati M,Ranucci E,Ferruti P,Lembo D

更新日期：2016-04-01 00:00:00

abstract：:Three-dimensional constructs formed by cells embedded in an exogenous scaffold could not represent a faithful in vitro replica of native and functional tissues. In this work we produced an endogenous human skin equivalent by means of a tissue engineering process that induces the full morphogenesis of functional dermal...

journal_title：Biomaterials

authors： Casale C,Imparato G,Urciuolo F,Netti PA

更新日期：2016-09-01 00:00:00

abstract：:Poly(vinyl alcohol)-heparin hydrogels with varying water content were synthesized for use as sensor catheter membranes. Films were cast from aqueous mixtures of poly(vinyl alcohol) (PVA), a photosensitive cross-linker p-diazonium diphenyl amine polymer (PA), glutaraldehyde (GA) and heparin. After drying, the films wer...

journal_title：Biomaterials

authors： Brinkman E,van der Does L,Bantjes A

更新日期：1991-01-01 00:00:00

abstract：:Since the pore size distribution of a material in contact with bone is decisive for its type of link with the tissue, many granules are commercially available as fillers and as bone reconstructing materials. We propose a new technological procedure. The optimum architectural design for obtaining the most suitable link...

journal_title：Biomaterials

authors： Fabbri M,Celotti GC,Ravaglioli A

更新日期：1994-05-01 00:00:00

abstract：:To prevent wear debris-induced osteolysis and aseptic loosening, cross-linked ultra-high molecular weight polyethylene's (UHMWPE) with improved wear resistance have been developed. Hip simulator studies have demonstrated very low wear rates with these new materials leading to their widespread clinical use. However, th...

journal_title：Biomaterials

authors： Sethi RK,Neavyn MJ,Rubash HE,Shanbhag AS

更新日期：2003-07-01 00:00:00

abstract：:A total of 60 cylindrical 6 x 6 mm samples of a macroporous biphasic calcium phosphate (MBCP) ceramic were implanted into a distal femoral site in 30 rabbits. These samples represented six kinds of implants with two different macropore diameters and three different macroporosity percentages. Analysis of backscattered ...

journal_title：Biomaterials

authors： Gauthier O,Bouler JM,Aguado E,Pilet P,Daculsi G

更新日期：1998-01-01 00:00:00

abstract：:A photografting technique to produce functional groups of silanol able to induce apatite nucleation was attempted on polyethylene substrate for biomimetic formation of bone-mineral-like apatite layer on its surface. The polyethylene surface was subjected to vapor-phase photografting of vinyltrimethoxysilane and subseq...

journal_title：Biomaterials

authors： Kim HM,Uenoyama M,Kokubo T,Minoda M,Miyamoto T,Nakamura T

更新日期：2001-09-01 00:00:00

abstract：:The advancement in gene therapy relies upon the discovery of safe and efficient delivery agents and methods. In this study, we report the design and synthesis of a cationic bolaamphiphile as a non-viral gene delivery agent. The bolaamphiphile is composed of 1,12-diaminododecane as the central hydrophobic unit linked t...

journal_title：Biomaterials

authors： Khan M,Ang CY,Wiradharma N,Yong LK,Liu S,Liu L,Gao S,Yang YY

更新日期：2012-06-01 00:00:00

abstract：:The role of albumin in the mineralisation process of commercial hydroxyapatite (HAp) and synthesised biphasic (HAp-tricalcium phosphate) ceramics in a bufferless simulated inorganic plasma (HBSS) was investigated by conventional in vitro tests and static and dynamic wettability measurements. Albumin was either pre-ads...

journal_title：Biomaterials

authors： Marques PA,Serro AP,Saramago BJ,Fernandes AC,Magalhães MC,Correia RN

更新日期：2003-02-01 00:00:00

abstract：:We have developed a silver-releasing biomaterial with promising potential for wound healing applications. The material is made of ultrashort peptides which can self-assemble in water to form hydrogels. Silver nanoparticles (Ag NPs) were synthesized in situ within the biomaterial, using only UV irradiation and no addit...

journal_title：Biomaterials

authors： Reithofer MR,Lakshmanan A,Ping AT,Chin JM,Hauser CA

更新日期：2014-08-01 00:00:00

abstract：:A series of in vitro screening assays for the preliminary selection of biomaterials for use in the fabrication of artificial corneas (keratoprostheses) (KPros) have been investigated. These screening assays assessed the initial binding of inflammatory and cell adhesive proteins, activation of inflammatory proteins, ad...

journal_title：Biomaterials

authors： Sandeman SR,Lloyd AW,Tighe BJ,Franklin V,Li J,Lydon F,Liu CS,Mann DJ,James SE,Martin R

更新日期：2003-11-01 00:00:00

abstract：:Neural stem cells (NSCs) have the capacity to differentiate into neurons, astrocytes, and oligodendrocytes. Accordingly, NSCs hold great promise in drug screening and treatment of several common diseases. However, a major obstacle in applied stem cell research is the limitation of synthetic matrices for culturing stem...

journal_title：Biomaterials

authors： Lewicka M,Hermanson O,Rising AU

更新日期：2012-11-01 00:00:00

abstract：:In the traditional Chinese medicine, Gu-Sui-Bu [Drynaria fortunei (kunze) J. Sm] has been reported as a good enhancer for bone healing. In this experiment, we investigate the biochemical effects of this traditional Chinese medicine on the bone cells culture. Different concentrations of crude extract of Gu-Sui-Bu were ...

journal_title：Biomaterials

authors： Sun JS,Lin CY,Dong GC,Sheu SY,Lin FH,Chen LT,Wang YJ

更新日期：2002-08-01 00:00:00

abstract：:Stem cell transplantation is a promising therapeutic strategy for acute or chronic ischemic cardiomyopathy. A major limitation to efficacy in cell transplantation is the low efficiency of retention and engraftment, due at least in part to significant early "wash-out" of cells from coronary blood flow and heart contrac...

journal_title：Biomaterials

authors： Vandergriff AC,Hensley TM,Henry ET,Shen D,Anthony S,Zhang J,Cheng K

更新日期：2014-10-01 00:00:00

abstract：:In this study, acrylamide-maleic acid hydrogels containing different amounts of maleic acid have been prepared by irradiating with gamma radiation. They have been used in experiments on bovine serum albumin (BSA) adsorption. Acrylamide-maleic acid hydrogel containing 60 mg of maleic acid and irradiated at 5.20 kGy has...

journal_title：Biomaterials

authors： Saraydin D,Karadağ E,Oztop HN,Güven O

更新日期：1994-09-01 00:00:00

abstract：:Cell delivery in cell therapy is typically challenged by the low cell survival rate and immunological rejection during cells injection and circulation. Encapsulation of cells with semipermeable hydrogels or membranes can improve cell viability by resisting high shear force and inhibit immune response with the physical...

journal_title：Biomaterials

authors： Yang J,Yang Y,Kawazoe N,Chen G

更新日期：2019-03-01 00:00:00

abstract：:Cytotherapeutic approaches have been investigated to overcome the limitations of existing procedures for periodontal regeneration. In this study, cell sheet transplantation was performed using three kinds of mesenchymal tissue (periodontal ligament, alveolar periosteum, and bone marrow)-derived cells to compare the di...

journal_title：Biomaterials

authors： Tsumanuma Y,Iwata T,Washio K,Yoshida T,Yamada A,Takagi R,Ohno T,Lin K,Yamato M,Ishikawa I,Okano T,Izumi Y

更新日期：2011-09-01 00:00:00

abstract：:The efficient delivery of short interfering RNA (siRNA) is an enormous challenge in the field of gene therapy. Herein, we report a delivery nanosystem based on programmed DNA self-assembly mammalian target of rapamycin (mTOR) siRNA-loaded DNA nanotubes (DNA-NTs). We demonstrate that these siRNA-DNA-NTs can be effectiv...

journal_title：Biomaterials

authors： You Z,Qian H,Wang C,He B,Yan J,Mao C,Wang G

更新日期：2015-10-01 00:00:00

abstract：:The application of non-viral gene delivery vectors is often accompanied with the poor correlation between transfection efficiency and the safety profiles of vectors. Vectors with high transfection efficiencies often suffer from high toxicities, making it unlikely to improve their efficiencies by increasing the DNA dos...

journal_title：Biomaterials

authors： Zheng N,Yin L,Song Z,Ma L,Tang H,Gabrielson NP,Lu H,Cheng J

更新日期：2014-01-01 00:00:00