Changes of nuclear DNA content in different types of nasopharyngeal epithelium.

Abstract:

:The unclear DNA content was measured with flow cytometry (FCM) in 167 specimens of normal nasopharyngeal epithelium (NE), adjacent tissue to carcinoma (ATC) and nasopharyngeal carcinoma (NPC). All 20 patients with NE showed diploid, whereas 38 (38%) of 101 patients with NPC, 7 (58%) of 12 patients with recurrent NPC, 6 (30%) of 20 patients with ATC and 2 (33%) of 6 patients with NE, positive to EBVCA-IgA test, showed nondiploid. In addition, cellular proliferation index (PI) of diploid NPC and diploid ATC, though differed nonsignificantly, was significantly increased as compared with that of NE (P < 0.01). The rate of cervical metastasis in nondiploid NPC was significantly higher than that in diploid NPC (P < 0.025).

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Zhao SP,Tao ZD,Xiao JY,Xiao PT,Peng YY

subject

Has Abstract

pub_date

1994-05-01 00:00:00

pages

371-4

issue

5

eissn

0366-6999

issn

2542-5641

journal_volume

107

pub_type

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