Abstract：
:We have isolated, characterized and quantified the immunocompetent cells present in the extravascular hepatic compartment at various stages after Plasmodium yoelii malaria infection with sporozoites. Cytological analyses revealed a predominantly lymphoid population. In mice with a primary infection, the predominant cells were CD4+, CD8+ and B lymphocytes. In fully protected mice, CD3+ CD4- CD8- and polymorphonuclear cells, particularly eosinophils, were most common. The significance of changes in subpopulations is discussed in relation to antigen presentation and host-protective mechanisms.
journal_name
Immunologyjournal_title
Immunologyauthors
Faure P,Marussig M,Goossens P,Miltgen F,Mazier Dsubject
Has Abstractpub_date
1994-08-01 00:00:00pages
645-50issue
4eissn
0019-2805issn
1365-2567journal_volume
82pub_type
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