Abstract：
:Eight human subjects were exposed to 2 h of walking on the perimeter of a horizontally rotating disc with the body remaining still in space. After adaptation to this experience subjects were blindfolded and asked to walk straight ahead on firm ground. When doing so all subjects generated curved walking trajectories of radii ranging from 65 to 200 inches and angular velocities from 7 to 20 deg/s. Subsequent trials over the next half hour revealed retained, but decreasing, trajectory curvature. Angular velocities associated with these trajectories were well above vestibular sensory threshold, yet all subjects consistently perceived themselves as walking straight ahead. The blindfolded subjects were also asked to propel themselves in a straight line in a wheel chair. Post-adaptation wheel chair trajectories showed no change from those before adaptation. Hence we infer that it was the relation between somatosensory/motor elements of gait and the perception of trunk rotation that had been remodelled during walking on the turning disc. This novel form of adaptive plasticity presumably serves to maintain optimal values of central neural parameters that control the trajectory of locomotion. The findings may have significant implications for the diagnosis and rehabilitation of locomotor and vestibular disorders.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Gordon CR,Fletcher WA,Melvill Jones G,Block EWdoi
10.1007/BF00230658subject
Has Abstractpub_date
1995-01-01 00:00:00pages
540-5issue
3eissn
0014-4819issn
1432-1106journal_volume
102pub_type
临床试验,杂志文章abstract：:Corticofugal influence upon lateral geniculate units was evaluated by inactivating the visual cortex with a topical application of 3M KCL in rabbits. The results revealed a decrease of spontaneous firing in slow P cells following cortical depression suggesting a tonic corticofugal influence. The most consistently obse...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236189
更新日期：1977-09-28 00:00:00
abstract：:Earlier studies have suggested an impairment in the attention and eye movement control of children with ADHD. An important phenomenon in the control of attentional shifts and eye movements is the inhibition of return (IOR), which states that our brain works in a way that prevents our attention from returning to a spat...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1362-8
更新日期：2003-03-01 00:00:00
abstract：:The control of upright stance is commonly explained on the basis of the single inverted pendulum model (ankle strategy) or the double inverted pendulum model (combination of ankle and hip strategy). Kinematic analysis using the uncontrolled manifold (UCM) approach suggests, however, that stability in upright standing ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4576-x
更新日期：2016-06-01 00:00:00
abstract：:In many daily situations, balance control is associated with a cognitive activity such as reading or a simple calculation. The objective of this study was to investigate the relationship between these two specific human activities, especially the influence of visual cues and support surface stability on body sway duri...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3913-1
更新日期：2014-07-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0202-z
更新日期：2006-04-01 00:00:00
abstract：:Single cell activity was recorded from the putamen in rhesus monkeys (Macaca mulatta) performing limb movements made both with and without a preceding preparatory "set" concerning the impending direction of movement. The monkeys were trained to perform an elbow step-tracking task, each trial of which required the subj...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00247293
更新日期：1987-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239301
更新日期：1980-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2257-8
更新日期：2010-06-01 00:00:00
abstract：:Through an experimental study of the stability properties of the human neuromuscular system while it performs simple point-to-point arm movements, this paper evaluates the concepts of equilibrium and virtual trajectories as a means of executing movement of the arm. Human subjects grasped the instrumented handle of a t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228024
更新日期：1995-01-01 00:00:00
abstract：:The vestibular nuclei and the interstitial nucleus of Cajal (INC) have been regarded as key elements of the velocity-to-position integrator for vertical eye movements. This paper reports a class of type II vestibular neurons that receives input from the INC and carries vertical eye movement signals that appear to repr...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1750-8
更新日期：2004-04-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4367-9
更新日期：2015-11-01 00:00:00
abstract：:The relationship between phantom limb phenomena and cortical reorganization was examined in five subjects with congenital absence of an upper limb and nine traumatic amputees. Neuromagnetic source imaging revealed minimal reorganization of primary somatosensory cortex in the congenital amputees (M=0.69 cm, SD 0.24) an...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050334
更新日期：1998-03-01 00:00:00
abstract：:High-status individuals have been found to be less attuned to the behaviour of others in the social environment, at least in the absence of any specific instructions to pay attention to them. Previous work using neural measures has shown that socioeconomic status (SES) influences the degree to which people are attuned...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-020-05761-7
更新日期：2020-04-01 00:00:00
abstract：:Visual stimulation alone is sufficient to produce visually induced postural reactivity (VIPR). While some studies have shown that VIPR increases with the velocity of a moving visual stimulus, others have shown that it decreases with the temporal frequency of an oscillating visual stimulus. These results seem contradic...
journal_title：Experimental brain research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00221-013-3592-3
更新日期：2013-08-01 00:00:00
abstract：:Realistic appearance and complexity in the visual field are known to affect the strength of vection (visually induced self-motion perception). Although surface properties of materials are, therefore, expected to be visual features that influence vection, to date, the results have been mixed. Here, we used computer gra...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-019-05620-0
更新日期：2019-10-01 00:00:00
abstract：:We investigated the association between the degree of lesion overlap with the corticospinal tract and walking performance before and after 4-weeks of partial body weight support (PBWS) treadmill training in 18 individuals (ten male, eight female) with a mean age 59 +/- 13 years (mean +/- SD), range 32-74 years, who we...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-1237-0
更新日期：2008-03-01 00:00:00
abstract：:In the present study, the sensitivity to sinusoidal linear accelerations in the plane of the utricular macula was tested in afferents. The head orientation relative to the translation axis was varied in order to determine the head position that elicited the maximal and minimal responses for each afferent. The response...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050219
更新日期：1997-11-01 00:00:00
abstract：:The representation of the two eyes in striate cortex (V1) of Cebus monkeys was studied by electrophysiological single-unit recordings in normal animals and by morphometric analysis of the pattern of ocular dominance (OD) stripes, as revealed by cytochrome oxidase histochemistry in V1 flat-mounts of enucleated animals....
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF02259100
更新日期：1992-01-01 00:00:00
abstract：:The present study investigated the function of the brain activity underlying the visual mismatch negativity (vMMN) event-related potential (ERP) component. Snowflake patterns (complex stimuli) were presented as deviants and oblique bar patterns (simple stimuli) as standards, and vice versa in a passive oddball paradig...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-019-05494-2
更新日期：2019-05-01 00:00:00
abstract：:When sight-reading a piece of music the eyes constantly scan the score slightly ahead of music execution. This separation between reading and acting is commonly termed eye-hand span and can be expressed in two ways: as anticipation in notes or in time. Previous research, predominantly in piano players, found skill-dep...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1719-3
更新日期：2009-04-01 00:00:00
abstract：:Effects of redox reagents on excitatory and inhibitory synaptic responses as well as on the bidrectional plasticity of alpha-amino-3-hydroxy-5-methylisoxazolepropionic acid (AMPA) and N-methyl-D-aspartate (NMDA) receptor-mediated synaptic responses were studied in CA1 pyramidal neurons in rat hippocampal slices. The o...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF02450332
更新日期：1997-02-01 00:00:00
abstract：:Nociceptive suppression of tonic voluntary electromyographic (EMG) activity in human hand muscles (cutaneous silent period, CSP) is in its functional organization consistent with a spinal protective reflex. Motoneuronal excitability and its modulation may also be investigated by conditioned motor evoked potentials (ME...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1372-2
更新日期：2008-07-01 00:00:00
abstract：:Cellular relationships between serotonin (5-HT) axons and tyrosine hydroxylase (TH)-containing neurons were examined by combined (3H)5-HT uptake radioautography and TH immunocytochemistry in the medial zona incerta (ZI) of adult rats, 7 and 50 days after an intracerebral injection of 5,7-Dihydroxytryptamine (5,7-DHT)....
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00250592
更新日期：1988-01-01 00:00:00
abstract：:In the frog's isolated head preparations, spontaneous activity was recorded from the whole nerve of the left horizontal semicircular canal (HC) for 6 min before and 16 min after destruction of the right labyrinth by heating or administration of d-tubocurarine (0.5 microliter, 5.10(-6)M) into the perilymph of the right...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235790
更新日期：1982-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-2156-y
更新日期：2005-05-01 00:00:00
abstract：:Cells in cat's area 17 respond optimally if elongated contrasts are presented at a certain angle or orientation with respect to the retina, or to the visual field, respectively (Hubel and Wiesel, 1962). The preferred orientation and the range of orientation sensitivity of cells in close proximity to one another have b...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00234062
更新日期：1975-12-22 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2962-y
更新日期：2012-02-01 00:00:00
abstract：:Survivin attenuates apoptosis by inhibiting cleavage of some cell proteins by activated caspase-3. We recently discovered strong up-regulation of survivin, primarily in astrocytes and a sub-set of neurons, after traumatic brain injury (TBI) in rats. In this study we characterized co-expression of survivin with activat...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-2362-2
更新日期：2005-11-01 00:00:00
abstract：:The synRas transgenic mice express constitutively activated Valin12-Harvey Ras in postnatal neocortical pyramidal neurons. This leads to somatodendritic hypertrophy, higher densities of spines and synapses, and an enhancement of synaptic long-term potentiation associated with an increased glutamate receptor-mediated a...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1688-y
更新日期：2009-12-01 00:00:00
abstract：:The dorsal and ventral streams model of action and perception suggests that reaching to grasp a tool for use involves integrated operation of the two streams. Few attempts have been made to test the limits of this integration in normal subjects. Twenty normal subjects reached for tools or geometric objects which were ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3501-9
更新日期：2013-06-01 00:00:00
