Abstract：
:Prior reports have described a transient and focal decline in transcranial magnetic stimulation (TMS)-induced motor evoked potential (MEP) amplitude following fatiguing motor tasks. However, the neurophysiological causes of this change in MEP amplitude are unknown. The aim of this study was to determine whether post-task depression of MEPs is associated with repetitive central motor initiation. We hypothesized that MEP depression is related to repeated central initiation of motor commands in task-related cortex independent of motor fatigue. Twenty healthy adults had MEPs measured from the dominant first dorsal interosseous (FDI) muscle before and after six different tasks: rest (no activity), contralateral fatiguing hand-grip, ipsilateral fatiguing hand-grip, contralateral finger tapping, ipsilateral finger tapping, and imagined hand-grip (motor imagery). Changes in MEPs from baseline were assessed for each task immediately following the task and at 2-min intervals until MEPs returned to a stable baseline. Measures of subjective effort and FDI maximum voluntary contractions (MVC) were also recorded following each task. A statistically significant drop in MEP amplitude was noted only with contralateral finger tapping and imagined grip. Changes in MEP amplitude did not correlate with subjective fatigue or effort. There was no significant change in FDI MVCs following hand-grip or finger-tapping tasks. This study extends our knowledge of the observed decline in MEP amplitude following certain tasks. Our results suggest that central initiation of motor programs may induce a change in MEP amplitude, even in the absence of objective fatigue.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Kluger BM,Palmer C,Shattuck JT,Triggs WJdoi
10.1007/s00221-011-2962-ysubject
Has Abstractpub_date
2012-02-01 00:00:00pages
585-90issue
4eissn
0014-4819issn
1432-1106journal_volume
216pub_type
杂志文章abstract：:There is extensive evidence that emotional information is better remembered than neutral information across long delays, especially if the delay interval contains an opportunity for sleep. However, as prior studies have focused on memory for negative stimuli, it is unclear whether positive memories benefit from time a...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3779-7
更新日期：2014-05-01 00:00:00
abstract：:Recent evidence suggests that brain injury can impair the ability to independently activate shoulder and elbow muscles. We hypothesized that if muscle activation patterns are constrained, then brain-injured subjects should not be able to accurately grade initial hand movement direction during reaching toward a broad r...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1055-3
更新日期：2002-04-01 00:00:00
abstract：:Immunoreactivities for tyrosine hydroxylase (TH), gamma-aminobutyric acid (GABA) and, in some cases, glutamic acid decarboxylase (GAD) were detected by light and electron microscopy in axons projecting into the median eminence and pituitary gland of various mammals (rats, mice, guinea pigs, cats, rabbits and hares). L...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229836
更新日期：1991-01-01 00:00:00
abstract：:While we walk through the environment, we constantly receive inputs from different sensory systems. For us to accomplish a given task, for example to reach a target location, the sensory information has to be integrated to update our knowledge of self-position and self-orientation with respect to the target so that we...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1146-1
更新日期：2002-08-01 00:00:00
abstract：:Here we aim to evaluate the ability of transcranial direct current stimulation (tDCS), which is applied over Wernicke's area and its right homologue, to influence lexical decisions and semantic priming and establish an involvement for temporo-parietal areas in lexical and semantic processing. Thirty-two subjects (17 w...
journal_title：Experimental brain research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00221-013-3416-5
更新日期：2013-04-01 00:00:00
abstract：:The prefrontal cortex (PFC) plays an important role in several cognitive functions, such as planning, decision making, and social behavior. We previously reported that periodontal sensory input significantly increases PFC activity during the motor task of maintaining occlusal (biting) force. However, the relationships...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-019-05630-y
更新日期：2019-11-01 00:00:00
abstract：:In order to investigate the role of mental rotation in the directional control of eye movements, we instructed subjects to make saccades in directions different from that of a visual stimulus (rotated saccades). Saccadic latency increased linearly with the amount of directional transformation imposed between the stimu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050765
更新日期：1999-06-01 00:00:00
abstract：:Two versions of the hypothesis that discrete movements are produced by shifts in the system's equilibrium point are considered. The first suggests that shifts are monotonic and end near the peak velocity of movement, and the second presumes that they are nonmonotonic ("N-shaped") and proceed until the end of movement....
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF00241503
更新日期：1995-01-01 00:00:00
abstract：:The contribution of different cortical regions to visuospatial attention can be probed with the help of perturbation techniques, such as transcranial magnetic stimulation (TMS). Repetitive TMS (rTMS) has also been suggested as a tool for the therapy of brain injuries, by adjusting the neural excitability of injured or...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1449-y
更新日期：2008-07-01 00:00:00
abstract：:The tectofugal pathway in birds has been reported to process primarily information from the contralateral eye. Although this pathway has access to the contralateral hemisphere by various connections, electrophysiological recordings up to now have failed to demonstrate any excitatory influence of visual stimulation in ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00271850
更新日期：1988-01-01 00:00:00
abstract：:It has long been assumed that the human central nervous system uses flexible combinations of several muscle synergies to effortlessly and efficiently control redundant movements. However, whether muscle synergies exist in the neural circuit remains controversial, and it is critical to examine the association between t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4253-5
更新日期：2015-06-01 00:00:00
abstract：:It is generally accepted that transferrin receptor is located in the endothelial cells of the brain, but its existence in other brain cell types is less established. In this study, a [(125)I]transferrin binding assay was used to determine whether there is transferrin receptor on the membrane of cultured rat cortical a...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050916
更新日期：1999-12-01 00:00:00
abstract：:Previous work has indicated that people do not use their judgment of a target's speed to determine where to hit it. Instead, they use their judgment of the target's changing position and an expected speed (based on the speed of previous targets). In the present study we investigate whether people also ignore the targe...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1556-8
更新日期：2003-10-01 00:00:00
abstract：:Several experiments have suggested that similar physiological substrates are involved in movement execution and motor imagery, and that the same laws of movement control apply to both processes. Using a mental chronometry paradigm, we examined the effects of movement direction and added mass on the duration of actual ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1012-1
更新日期：2002-04-01 00:00:00
abstract：:A strong subjective tendency exists for simultaneous sound frequencies forming an harmonic series (integer multiples of the fundamental) to "group" together into a unified auditory percept whose pitch is similar to that of the fundamental. The aim of the study was to determine whether cortical auditory evoked potentia...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1482-9
更新日期：2003-06-01 00:00:00
abstract：:Under anesthesia with N2O (70%) and halothane (2-4%), complex spikes of Purkinje cells were extracellularly recorded in the nodulus and flocculus of immobilized pigmented rabbits. Optokinetic stimulation (OKS) was delivered to each eye as repetitive movements of a random dot pattern. The visual field of each eye was d...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228792
更新日期：1990-01-01 00:00:00
abstract：:This study investigated the effects of declined accommodation on reading performance in non-native and native languages. Eighteen native Japanese speakers participated: eight presbyopes and ten non-presbyopes. In the experiment, participants were asked to scan, or sequentially read six-word items presented in two-line...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-019-05588-x
更新日期：2019-09-01 00:00:00
abstract：:In the present study, we investigated topographical differences between monocularly and binocularly evoked potential fields related to the retinal location and spatial frequency of grating stimuli. Electrical brain activity was recorded in 18 healthy adults using an array of 21 electrodes over the occipital areas. Ver...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229366
更新日期：1993-01-01 00:00:00
abstract：:Previous studies have reported abnormalities in fine hand and finger movements following interruption of the fasciculus cuneatus (FC) in primates. We report here that many of these deficits could be caused by an inability to actively regulate the position of the finger. Three macaques were trained to maintain the inde...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227785
更新日期：1993-01-01 00:00:00
abstract：:For a long time, a controversy has been proposed that whether the process of theory of mind is a result of domain-specific or domain-general changes (Wellman in The handbook of childhood cognitive development. Blackwell Publication, New Jersey, 2011). This event-related potential study explored the neural time course ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3661-7
更新日期：2013-11-01 00:00:00
abstract：:The action of delta-aminovaleric acid (AVA) on the muscle relaxant properties of baclofen, a GABAB receptor agonist, was investigated in two experimental models: (1) the pathologically increased muscle tone of the gastrocnemius muscle in spastic mutant Han-Wistar rats and (2) the Hoffmann (H)-reflex recorded from plan...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00247610
更新日期：1988-01-01 00:00:00
abstract：:5-Hydroxytryptamine (5-HT) has the most diverse set of receptors in comparison with any other neurotransmitter or hormone in the body. To date, seven families of 5-HT receptors have been characterized. A great number of studies have been published regarding the role of 5-HT and its receptors in seizures. However, with...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s00221-013-3757-0
更新日期：2014-02-01 00:00:00
abstract：:The executive functions, which depend on the adequate maturation and functioning of the prefrontal cortex and its connection to posterior zones, follow a process of development as age increases. This work studied changes in the absolute power (AP) of EEG activity recorded in the prefrontal and parietal areas during th...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3693-z
更新日期：2013-11-01 00:00:00
abstract：:In two monkeys, we measured the initial vergence eye movements elicited by sudden forward motion on a linear sled. Animals faced a tangent screen and experienced the translation while in darkness, fixating a small, centered spot, or viewing a large-field pattern. Forward movements elicited convergent responses that we...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1351-y
更新日期：2003-02-01 00:00:00
abstract：:Our aim was to describe the differences in the presence of trigger points (TrPs) in the shoulder muscles and to investigate the presence of mechanical hypersensitivity in patients with unilateral shoulder impingement and healthy controls. Twelve patients with strictly unilateral shoulder impingement and 10 matched con...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2196-4
更新日期：2010-05-01 00:00:00
abstract：:Light microscopic autoradiography and electron microscopy were used to trace the nigrothalamic projections and to study the sites of termination of this pathway in the cat. Injections of tritiated amino acids or electrolytic lesions were placed in the substantia nigra pars reticularis (SNr). An accumulation of radioac...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235569
更新日期：1978-11-15 00:00:00
abstract：:The goal of this study was to identify the control mechanism used for locomotion pointing regulation under different external temporal constraints. Subjects ( n=8) had to walk on a treadmill through a number of virtual hallways and cross a pair of gliding doors that opened and closed at a constant preset frequency (0....
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0990-8
更新日期：2002-03-01 00:00:00
abstract：:Objective attempts to characterize postural control in subjects with cerebellar (Cb) pathology have focused primarily on sagittal plane responses to static standing, semi-dynamic standing, and platform perturbation. Repeated, dynamic, functional movement may provide a better opportunity to study the effects of ataxia ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002219900291
更新日期：2000-05-01 00:00:00
abstract：:Our previous study showed an increase in total cholesterol level of the hippocampus after kainate-induced injury, but whether this is further metabolized to neurosteroids is not known. The first step in neurosteroid biosynthesis is the conversion of cholesterol to pregnenolone by the enzyme cytochrome P450 side chain ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-1209-4
更新日期：2008-03-01 00:00:00
abstract：:The present experiments were designed to investigate the neuronal mechanisms, at the level of the primary somatosensory cortex, which underlie the observation that somatosensory cortical potentials evoked by air puff stimuli directed at the forearm are decreased, in a nonspecific and widespread manner, during voluntar...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231455
更新日期：1991-01-01 00:00:00
