Abstract：
:Counts of callosal neurons retrogradely labeled by horseradish peroxidase (visualized using multiple substrates) were obtained in areas 17 and 18 of five kittens reared with their eyelids bilaterally sutured and of three kittens which had undergone bilateral enucleation on postnatal days 1--4. These counts were compared with those obtained in normal adult cats. The normal adult distribution of the callosal neurons results from the gradual postnatal reduction of a more widespread juvenile population. Binocular visual deprivation by lid suturing dramatically decreases the final number of callosal neurons and narrows their region of distribution (callosal zone) in areas 17 and 18. A less severe reduction in the final number of callosal neurons is caused by bilateral enucleation, which also increases the width of the callosal zone compared to that of normal cats. Thus, visual experience is necessary for the normal stabilization of juvenile callosal connections. However, since some callosal neurons form connections in the absence of vision, other influences capable of stabilizing juvenile callosal neurons also exist. These influences are probably antagonized by destabilizing influences or inhibited, when the eyes are intact.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Innocenti GM,Frost DOdoi
10.1007/BF00239301subject
Has Abstractpub_date
1980-01-01 00:00:00pages
365-75issue
4eissn
0014-4819issn
1432-1106journal_volume
39pub_type
杂志文章abstract：:Variations of the µ-opioid receptor gene OPRM1 have been shown to modulate pain perception with some evidence pointing towards a modulation of not only physical but also "psychological pain". In line with suggestions of a common neural network involved in the processing of physical pain and negative and distressing st...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4322-9
更新日期：2015-09-01 00:00:00
abstract：:1.) Eye movements were recorded in four Java monkeys (M. fascicularis) after unilateral microinjections (1 microliter, concentration 1 micrograms/microliter) of the GABA antagonist, bicuculline, and the GABA agonist, muscimol, into oculomotor related regions of the vestibular nuclei. Eye movements were investigated in...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228958
更新日期：1991-01-01 00:00:00
abstract：:Previous studies have proposed that selecting which hand to use for a reaching task appears to be modulated by a factor described as "task difficulty," defined by either the requirement for spatial precision or movement sequences. However, we previously reported that analysis of the movement costs associated with even...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-018-5423-z
更新日期：2019-02-01 00:00:00
abstract：:The genesis of the cuneothalamic neurons (CTNs) in the rat cuneate nucleus was determined by a double-labeling method using 5'-bromodeoxyuridine (BrdU), the thymidine analogue, and Fluoro-Gold (FG), a retrograde fluorescent tracer. BrdU-positive cells were observed in the cuneate nucleus in all rats receiving BrdU inj...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0950-3
更新日期：2002-02-01 00:00:00
abstract：:Load perturbations were applied to the arm of human subjects under conditions where both limb segments (upper arm and forearm) were free to move. The perturbations consisted of pulses of torque 50 ms in duration and of pseudo-random sequences of such pulses. They were applied to either the forearm or the upper arm. Un...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237573
更新日期：1986-01-01 00:00:00
abstract：:The cortical projections to neck muscle motoneurons were studied in normal subjects by electrical and magnetic transcranial brain stimulation. After magnetic stimulation with a large coil, motor evoked potentials were present in about 20% of relaxed and 100% of contracting neck muscles. The latency of these responses ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231857
更新日期：1991-01-01 00:00:00
abstract：:Single cells were recorded in layers A and A1 of the cat dorsal lateral geniculate nucleus (dLGN) with multibarrel micropipettes. Interocular inhibition ("binocular inhibition") was elicited by phase-reversing gratings presented monocularly to the nondominant eye. This inhibition was blocked by microiontophoretic appl...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239516
更新日期：1986-01-01 00:00:00
abstract：:Nerve cell bodies located within the white matter of the dorsal funiculus (DF neurons) have been previously observed but not described in detail. The present study examines the morphology, ontogeny, and projection of DF neurons utilizing Fluoro-Gold as a retrograde tracer, alone, and in combination with tritiated thym...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228128
更新日期：1990-01-01 00:00:00
abstract：:The 2-deoxyglucose (2-DG) autoradiographic technique was used to map functional activity in the central auditory system of the mongolian gerbil, throughout the period of functional onset. Uptake of 2-DG during exposure to 105 dB SPL wide band noise (WBN) was compared to silence in adults and in neonates at 12, 14, 16 ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239360
更新日期：1982-01-01 00:00:00
abstract：:Pyramidal cell structure varies systematically in occipitotemporal visual areas in monkeys. The dendritic trees of pyramidal cells, on average, become larger, more branched and more spinous with progression from the primary visual area (V1) to the second visual area (V2), the fourth (V4, or dorsolateral DL visual area...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0057-3
更新日期：2005-12-01 00:00:00
abstract：:The effects of left and right alignment on the Ebbinghaus illusion were investigated in three experiments. In Experiment 1, the Ebbinghaus illusion was presented on the left or right side, and the points of subjective equality (PSE) were measured. Only the central disk of the figure with small inducers was perceived l...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-018-5168-8
更新日期：2018-04-01 00:00:00
abstract：:Stimulation of cutaneous foot afferents has been shown to evoke a facilitation of the tibialis anterior (TA) EMG-activity at a latency of 70-95 ms in the early and middle swing phase of human walking. The present study investigated the underlying mechanism for this facilitation. In those subjects in whom it was possib...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050600
更新日期：1999-01-01 00:00:00
abstract：:We investigated the effect of spatial uncertainty on motor planning by using the cueing method in a reaching task (experiment 1). Discrete spatial cues indicated the different locations in which the target could be presented. The number of cues as well as their direction changed from trial to trial. We tested the adeq...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1453-1
更新日期：2003-06-01 00:00:00
abstract：:The organisation of the human neuromuscular-skeletal system allows an extremely wide variety of actions to be performed, often with great dexterity. Adaptations associated with skill acquisition occur at all levels of the neuromuscular-skeletal system although all neural adaptations are inevitably constrained by the o...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0547-y
更新日期：2006-11-01 00:00:00
abstract：:An aberrant crossed corticotectal pathway can be generated by removal of one visual cortex and the contralateral superior colliculus from newborn rats. This aberrant crossed corticotectal projection arises from the pyramidal neurons located in layer V of the visual cortex and terminates in a spatially orderly manner i...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235562
更新日期：1978-11-15 00:00:00
abstract：:The possibility that effects of fornix stimulation on units in the medial preoptic region (MPO) may be via an interposed neuron in the dorsal septum was investigated using electrophysiological techniques. We found a reciprocal monosynaptic linkage between the MPO and the dorsal, medial and fimbrial septal nuclei. When...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236041
更新日期：1986-01-01 00:00:00
abstract：:The blood-brain barrier hinders progress in the chemotherapy of brain tumors due to insufficient penetration of anticancer drugs into the brain tissue. Short-chain alkylglycerols affect the physicochemical properties of biological membranes. The enhancement of the blood-brain barrier permeability by intra-arterial adm...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000553
更新日期：2000-12-01 00:00:00
abstract：:Two rhesus monkeys were trained to make saccadic eye movements from a central fixation point towards a peripheral target. Saccadic reaction times (SRTs) were measured in the gap paradigm (200 ms pause between offset of fixation point and onset of peripheral target). Target position for extensive training (SRTs of 150 ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230109
更新日期：1990-01-01 00:00:00
abstract：:Dementia due to cerebral ischemic lesions is relatively common in the elderly. Since many of these lesions are probably caused by emboli, studying emboli-induced cerebral lesions in rabbits should, hopefully, provide information that is useful when searching for a means of preventing and treating vascular dementia in ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050622
更新日期：1999-01-01 00:00:00
abstract：:Serotonin reveals ineffective (subthreshold) pathways from the C2 lateral funiculus to ipsilateral phrenic motoneurons in spinalized rats. The objective of the present study was to investigate serotonergic modulation of crossed-spinal pathways to contralateral phrenic motoneurons. Rats (n = 10) were anesthetized (uret...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00243214
更新日期：1994-01-01 00:00:00
abstract：:Young children rely heavily on vision for postural control during the transition to walking. Although by 10 years of age, children have automatic postural responses similar to adults, it is not clear when the integration of sensory inputs becomes fully developed. The purpose of this study was to examine this transitio...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0109-8
更新日期：2006-01-01 00:00:00
abstract：:Successful results obtained by training sessions using optokinetic (OK) stimulations in order to rehabilitate patients with balance disorders motivated this study. The purpose of the study was to measure eye movement parameters and body stabilization during OK stimulation before and after the rehabilitation program. T...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/BF00232446
更新日期：1994-01-01 00:00:00
abstract：:The brain noradrenaline (NA) system is known to modulate ischemic neuronal damage, and the turnover of NA has been suggested to increase in the early recovery period following cerebral ischemia. Using HPLC and gas chromatography-mass spectrometry we analyzed the tissue levels of NA and its metabolites, 3,4-dihydroxyph...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230938
更新日期：1992-01-01 00:00:00
abstract：:Reduced short-interval intracortical inhibition (SICI) is reported in Parkinson's disease (PD) and is considered to reflect abnormal GABAergic inhibitory system of the primary motor cortex in PD. We have recently shown, however, that SICI using anterior-posterior directed currents in the brain was normal in focal dyst...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2829-2
更新日期：2011-10-01 00:00:00
abstract：:The relationship between phantom limb phenomena and cortical reorganization was examined in five subjects with congenital absence of an upper limb and nine traumatic amputees. Neuromagnetic source imaging revealed minimal reorganization of primary somatosensory cortex in the congenital amputees (M=0.69 cm, SD 0.24) an...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050334
更新日期：1998-03-01 00:00:00
abstract：:Parkinson's disease (PD) adversely affects information processing and motor performance. The impact of aerobic exercise on modifying the deleterious effects of PD underlying information and motor control processes is not well established. The primary aim of this project was to determine the effects of an 8-week high i...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-020-06009-0
更新日期：2021-01-04 00:00:00
abstract：:By measuring the forces applied by each limb supporting the weight of the standing quadruped (cat), before and during elicitation of the placing reaction, it was possible to examine quantitatively and qualitatively the postural events which preceded and accompanied forelimb displacement. The findings are summarized as...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237713
更新日期：1979-10-01 00:00:00
abstract：:We studied intermanual motor transfer for right-to-left or left-to-right direction of transfer between either proximal or distal upper extremity muscle groups. The influence of previously acquired motor engrams (original learning, OL) on learning efficiency of the contralateral side (transfer learning, TL) was examine...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/BF00228105
更新日期：1996-03-01 00:00:00
abstract：:Double-labeling combined with elution-restaining immunofluorescence techniques were used to analyze the extent of coexistence among the peptides cholecystokinin (CCK), peptide histidine-isoleucine (PHI)/vasoactive intestinal polypeptide (VIP), substance P and the catecholamine-synthesizing enzyme tyrosine hydroxylase ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00250598
更新日期：1988-01-01 00:00:00
abstract：:The firing patterns of alpha and gamma efferent fibres and of group I and group II afferent fibres innervating the gastrocnemius muscle were observed during spontaneous locomotor movements in the thalamic cat. Multi-unit discharges of each kind of fibre were obtained by electronic sorting of the action potentials from...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00340493
更新日期：1986-01-01 00:00:00
