Preliminary study on controlled hypotension induced by nimodipine in craniocerebral surgery.

Abstract:

:Nimodipine, produced in China, was applied to lower the blood pressure (BP) in 20 cases in craniocerebral operation. 0.02% solution of Nimodipine was dripped intravenously (by 0.02% of density), at a preliminary speed of 600-800 micrograms/min, and 4-12 mg of total dose. Mean arterial pressure (MAP) decreased and maintained at 7.3-8.0 kPa, and lasted 30-60 minutes. The scopes of decreasing pressure were 33.0%-37.7% of MAP, 31.6%-35.6% of systolic pressure (SP), and 36.1%-41.9% of diastolic pressure (DP). The results of lowering pressure which reduced the intraoperative bleeding were significant. After withdrawal of drug supply for 15-30 minutes, the BP raised up to the normal level. No "rebounding BP rise" occurred.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Zhang P,Wang B,Wang E,Chen X

subject

Has Abstract

pub_date

1995-06-01 00:00:00

pages

420-2

issue

6

eissn

0366-6999

issn

2542-5641

journal_volume

108

pub_type

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