Abstract:
:Norepinephrine (NE) and dopamine (DA) levels and turnover were measured in 17 discrete brain regions of Swiss-Webster (NIH) mice made aggressive by prolonged isolation. The NE steady state level was significantly lower in olfactory tubercle and substantia nigra and significantly higher in the septal area of the aggressive mice when compared to the isolated non-fighter controls. NE turnover was only higher in the A-10 region of the aggressors. DA steady state level and turnover was lower in olfactory tubercle and higher in caudate putamen of the aggressors. The significance of these changes in isolation-induced aggression is discussed.
journal_name
Brain Res Bulljournal_title
Brain research bulletinauthors
Tizabi Y,Massari VJ,Jacobowitz DMdoi
10.1016/0361-9230(80)90287-7subject
Has Abstractpub_date
1980-01-01 00:00:00pages
81-6issue
1eissn
0361-9230issn
1873-2747pii
0361-9230(80)90287-7journal_volume
5pub_type
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