Abstract：
:The innervation pattern of distal muscle fibers of the opener muscle of walking legs of crayfish (Astacus leptodactylus) was investigated using methylene-blue staining, cobalt infiltration, and electron microscopy. A quantitative analysis of the entire innervation of single muscle fibers was attempted. It was found that instead of the generally assumed parallel array of numerous excitatory and inhibitory terminals, innervation consists of only a few branched terminals. The branches of excitatory and inhibitory terminals lie side-by-side. Both types are characterized by numerous varicosities (see Fig. 9B). The aggregate length of excitatory as well as inhibitory terminals on one muscle fiber is, on the average, about 1,500 micrometer with a total of 152 varicosities spaced about 10 micrometer apart. The average diameter of the varicosities is 4.26 micrometer, that of the connecting thin segments about 0.5 micrometer. Total terminal surface of motor or inhibitory terminals amounts to about 10,000 micrometers2 per muscle fiber. There are approximately 2,000 motor synapses on each muscle fiber, but their average total area is only about 6% of the terminal membrane area, or 0.06% of the (idealized) muscle fiber surface. There are conspicuous differences in the postsynaptic specializations associated with excitatory and inhibitory terminals; these are described in detail. The results are discussed in a functional context and with regard to design and results of electrophysiological experiments.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Florey E,Cahill MAdoi
10.1007/BF00213750subject
Has Abstractpub_date
1982-01-01 00:00:00pages
527-41issue
3eissn
0302-766Xissn
1432-0878journal_volume
224pub_type
杂志文章abstract：:Exocytotic release of the secretory granules of the endocrine cells in the midgut of a cockroach, Periplaneta americana, was studied by means of fixation with tannic acid in combination with glutaraldehyde and osmium tetroxide. A sequence of images indicative of exocytosis suggests the following steps in this process:...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00213851
更新日期：1982-01-01 00:00:00
abstract：:Neuroblastoma cells grown on substrates in culture develop long processes and assume the morphology of normal neurons as judged light microscopically. The development of synapses in the cultured tissue is studied by periodic electron microscopic examination of the areas of contact between cells. The initial explants a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00232282
更新日期：1980-01-01 00:00:00
abstract：:Bone morphogenetic proteins (BMPs) induce cartilage and bone formation at both bony and non-bony sites. We examined the possibility whether BMP-2 induces differentiation of osteoblast progenitors into chondroblast lineage cells using organ culture and cell culture prepared from the calvaria of newborn mouse. BMP-2 sti...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050562
更新日期：1996-04-01 00:00:00
abstract：:The ultrastructure of adult male rat pinealocytes was studied after orchidectomy and orchidectomy followed by LH-RH administration. Castration causes an increased development of the rough endoplasmic reticulum and the Golgi apparatus as well as an increase in the number of lipid droplets and lysosomes. The changes aft...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219145
更新日期：1976-04-02 00:00:00
abstract：:The distribution pattern of adrenergic fibres innervating the ocular choroid membrane of the chicken was studied by means of fluorescence and electron microscopy. In addition, the origin of these fibres was investigated after superior cervical ganglionectomy. Adrenergic axons reach the choroid, partly forming the peri...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00213222
更新日期：1982-01-01 00:00:00
abstract：:The fine structure of luminal surface of clearly identified portions of uriniferous tubules has been studied by scanning electron microscopy to elucidate some controversies concerning the topography of certain surface formations. The results show a characteristic pattern of the luminal surface in the region of Henle's...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215128
更新日期：1976-02-06 00:00:00
abstract：:Wnts are secreted glycoproteins that play multiple roles in early development, including the differentiation of precursor cells. During this period, gradients of Wnts and other morphogens are formed and regulate the differentiation and migration of neural progenitor cells. Afterwards, Wnt signalling cascades participa...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-014-1996-4
更新日期：2015-01-01 00:00:00
abstract：:Growing numbers of translational genomics studies are based on the highly efficient and versatile zebrafish (Danio rerio) vertebrate model. The increasing types of zebrafish models have improved our understanding of inherited kidney diseases, since they not only display pathophysiological changes but also give us the ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-017-2593-0
更新日期：2017-07-01 00:00:00
abstract：:Regions within frog semitendinosus muscle that are rich in tonic muscle cells were identified histochemically by myosin adenosine triphosphatase- and succinic dehydrogenase-staining procedures. Bundles of cells still attached to tendinous insertions were removed from those sites, prepared for electron microscopy and s...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00213937
更新日期：1986-01-01 00:00:00
abstract：:Pancreatic acinar cells of euthermic, hibernating and arousing individuals of the hazel dormouse Muscardinus avellanarius (Gliridae) have been observed at the electron-microscopic level and analysed by means of ultrastructural morphometry and immunocytochemistry in order to investigate possible fine structural changes...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051082
更新日期：1998-06-01 00:00:00
abstract：:The influence of adrenalectomy and administration of hypertonic saline on the amount of vasopressin, oxytocin, and neurophysin contained in the median eminence and the neural lobe of rats was studied by means of the following methods: (i) morphometric and microphotometric analyses of aldehyde fuchsin-stained histologi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00206271
更新日期：1983-01-01 00:00:00
abstract：:Immunohistochemical localization of luteinizing hormone-releasing hormone (LH-RH), during different phases of the estrus cycle, in the preoptic, suprachiasmatic and arcuate nuclei, and in the OVLT of rats, with special emphasis on the ependymal cells, was studied by light, fluorescent and electron microscopy, by using...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221371
更新日期：1976-10-06 00:00:00
abstract：:The effects of high dose injections of corticotropin-releasing hormone (CRH) on the adrenal cortex of hypophysectomized rats were studied at the light- and electron-microscopical levels. Adrenocortical atrophy induced by hypophysectomy could be reduced by daily i.p. injection of 10 micrograms (3 nmol) CRH given for 3 ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00297501
更新日期：1990-04-01 00:00:00
abstract：:Previous studies have revealed a remarkable capacity of intracerebral grafts of embryonic brain tissue to establish extensive axonal connections with denervated areas in the brains of adult rats. In the present study we have explored the possibilities of using grafts in the spinal cord to substitute for the loss of no...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216024
更新日期：1983-01-01 00:00:00
abstract：:The complex physiology of the gastrointestinal (GI) tract must permanently be adjusted according to the composition of ingested food, which requires continuous monitoring by appropriate sensory systems. Sensing the dietary constituents is thought to be mediated by chemosensory cells residing in the mucosa of the GI tr...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-011-1137-2
更新日期：2011-05-01 00:00:00
abstract：:The mole has a single pair of accessory sex organs with features of both the prostate and the seminal vesicle, for which the term prostate gland is not appropriate. Seasonal changes occuring in this gland were related to four periods: a) the quiescence period, b) the maturation period, c) the active period and d) the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218718
更新日期：1976-12-10 00:00:00
abstract：:The opioid peptide dynorphin A (1-17) is the third transmitter identified in the striatonigral projection, the other two being gamma-aminobutyric acid (GABA) and substance P. The ultrastructural features of the dynorphinergic terminals in substantia nigra/pars reticulata were studied using pre-embedding immunocytochem...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00329443
更新日期：1990-07-01 00:00:00
abstract：:Considerable evidence indicates that the state of ocular connective tissues and their response in glaucomatous disease affect the degree of glaucoma damage. Both experimental and clinical data suggest that improved diagnostic and prognostic information can be derived from the assessment of the mechanical responsivenes...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-013-1603-0
更新日期：2013-08-01 00:00:00
abstract：:Collagens are the most abundant proteins in vertebrate tissues and constitute significant moieties of the extracellular matrix (ECM). The determination of the collagen content is of relevance not only in the field of native tissue research, but also regarding the quality assessment of bioengineered tissues. Here, we d...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-010-1113-2
更新日期：2011-03-01 00:00:00
abstract：:Nematocysts are characteristic organelles of the phylum Cnidaria. The free-living Platyhelminth Microstomum lineare preys on Hydra oligactis and sequesters nematocysts. All nematocyst types become phagocytosed without adherent cytoplasm by intestinal cnidophagocytes. Desmoneme and isorhiza nematocysts disappear within...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03149-w
更新日期：2020-01-01 00:00:00
abstract：:Correlations between the presence of surface coat and immobilization antigen of Paramecium tetraurelia were studied. Supravital, partial removal of the surface coat resulted in accelerated response of monobacterially and axenically grown cells to the homologous antiserum. Ciliates pretreated with trypsin or pronase (0...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219984
更新日期：1977-07-11 00:00:00
abstract：:The effects of light and dark on photoreceptors of the brackish-water polychaete annelid Nereis limnicola were studied by electron microscopy. Animals dark-adapted for one or two days exhibited well-formed straight microvilli (rhabdomeres) on the sensory cell processes. Continuous illumination of worms for one or two ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00225427
更新日期：1985-01-01 00:00:00
abstract：:Pituitary somatotrops were localized in four species from the genus Oncorhynchus using an antiserum to chum salmon (Oncorhynchus keta) growth hormone. The antiserum cross-reacted specifically with the acidophils in the caudal pars distalis of all species tested. Corroborative immunodiffusion studies were also conducte...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218126
更新日期：1983-01-01 00:00:00
abstract：:Marked changes in mice pubic symphysis occur by the end of pregnancy. Tissue remodeling involves a dynamic balance between cell proliferation and programmed cell death as well as changes in the extracellular matrix components. Therefore, it is important to consider both of these cellular behaviors when investigating t...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0463-x
更新日期：2007-10-01 00:00:00
abstract：:Semaphorin 3A (Sema3A) axon repellant serves multiple developmental functions. Sema3A mRNAs are expressed in epithelial and mesenchymal components of the developing incisor in a dynamic manner. Here, we investigate the functions of Sema3A during development of incisors using Sema3A-deficient mice. We analyze histomorp...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-014-1839-3
更新日期：2014-07-01 00:00:00
abstract：:The mechanism of cell death which occurs during Chagas' cardiopathy is disputed. To address this issue we analyzed the molecular pathways implicated in the death of cardiomyocytes during T. cruzi invasion and found that they undergo apoptosis during both in vitro and in vivo infections. However, the death rates and on...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-003-0782-5
更新日期：2003-11-01 00:00:00
abstract：:Human fibroblasts and HeLa cells were treated with bunaftine (N-butyl-N-/2-(diethylamino)ethyl/-1-naphthalenecarboxamide ) in vitro. At concentrations of 0.5-2.0 mM, the drug caused contraction and rounding of the cells with loss of microvilli-like processes. Aggregates of dense, partly granular, partly fibrillar mate...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216519
更新日期：1984-01-01 00:00:00
abstract：:To determine whether lipid-secreting cells have cytosolic Ca2+ concentration ([Ca2+]c)-related secretory mechanisms, morphological changes and intracellular calcium dynamics of Harderian glands of guinea pigs stimulated by secretagogue were studied by electron microscopy and Fura-2/AM digital image analysis. Control g...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00327979
更新日期：1993-10-01 00:00:00
abstract：:Post-translational modification of histone proteins, such as the methylation of lysine and arginine residues, influences the higher order of chromatin and leads to gene activation or silencing. Histone methyltransferases or demethylases actively add or remove various methylation marks in a cell-type-specific and conte...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-014-1842-8
更新日期：2014-06-01 00:00:00
abstract：:Large granular lymphocytes (LGL) comprise a natural defense system in the liver and exert an inhibitory effect on tumor cell metastasis. In order to demonstrate the maturation of LGL in the liver from the morphological aspect, we evaluated electron-microscopically the frequency of 0.2 micron vesicles (rod-cored and "e...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00354799
更新日期：1994-04-01 00:00:00
