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An autoradiographic demonstration of prazosin binding to arterial vessels in the rat.

Abstract：

:Prazosin is believed to have an antihypertensive action due to a selective blockade of alpha-adrenoceptors on vascular smooth muscle. Using an in vitro autoradiographic technique specific binding of [3H]prazosin to the abdominal aorta and renal artery in the rat has been shown. The binding of [3H]prazosin to arterial vessels may provide some evidence for the site where prazosin exerts its antihypertensive action.

journal_name

Eur J Pharmacol

journal_title

European journal of pharmacology

authors

Dashwood M,Bagnall J

doi

10.1016/0014-2999(82)90380-6

subject

Has Abstract

pub_date

1982-02-19 00:00:00

pages

121-3

issue

1

eissn

0014-2999

issn

1879-0712

pii

0014-2999(82)90380-6

journal_volume

78

pub_type

杂志文章

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