Abstract：
:Blood was collected from 20 patients with varicocele (15 in the infertile group and 5 in the incidental varicocele group) at the time of high ligation by insertion of a catheter into the internal spermatic vein toward the renal side. Simultaneously, blood was obtained from the antecubital vein. The levels of cortisol, prostaglandin (PG)(A + B), PGE, and PGF in these blood samples were measured. Although no differences in cortisol and PG(A + B) levels were observed between internal spermatic and peripheral vein bloods in varicocele patients examined, PGE and PGF levels were higher in internal spermatic venous bloods than in peripheral venous bloods. Differences in PGF levels between the samples of blood from the internal spermatic vein and from the peripheral vein in cases of the infertile group were larger than those of the incidental varicocele group. PGE and PGF in internal spermatic vein blood samples were correlated. The possibility that PGE and PGF, refluxed from the renal vein to the testes via the internal spermatic vein in varicocele patients, disturbs spermatogenesis is discussed.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Ito H,Fuse H,Minagawa H,Kawamura K,Murakami M,Shimazaki Jdoi
10.1016/s0015-0282(16)46043-7subject
Has Abstractpub_date
1982-02-01 00:00:00pages
218-22issue
2eissn
0015-0282issn
1556-5653pii
S0015-0282(16)46043-7journal_volume
37pub_type
杂志文章abstract：:Hormonal profiles were compared in 14 ovulatory women who were treated with two different doses of gonadotropins in successive in vitro fertilization cycles. All patients suffered from mechanical causes of infertility. Serum estradiol (E2), follicle-stimulating hormone (FSH), luteinizing hormone (LH), and progesterone...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1988-06-01 00:00:00
abstract：OBJECTIVE:To induce apoptosis of endometriotic cells of patients with endometriosis. DESIGN:To demonstrate that polyglycolic acid/chitosan glue directly inhibits cell proliferation by inducing apoptosis. SETTING:University hospital infertility center. PATIENT(S):Twelve women who visited the center for infertility th...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.01.127
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVE:To identify the value that women with pelvic inflammatory disease (PID) assign to the health impact of future infertility. DESIGN:Cross-sectional observations on patient preferences. SETTING:Participants in an existing multicenter clinical trial of PID treatment options. PATIENT(S):Five hundred thirty-two ...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究
doi：10.1016/j.fertnstert.2003.09.064
更新日期：2004-05-01 00:00:00
abstract：:Twelve women of normal weight (ages 17 to 36 years) with scanty menstrual bleeding were studied. They had no signs of virilization, gynecologic or endocrine pathology, or past history of hormonal treatment. Five women (group 1) experienced withdrawal bleeding after a 3-day course of chlormadinone acetate (2 mg/day) an...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)43213-9
更新日期：1978-04-01 00:00:00
abstract：OBJECTIVE:To characterize the molecular mechanisms by which estrogens reduce adipose tissue mass, with particular focus on genes involved in lipogenesis. DESIGN:This study involves one arm of an open randomized clinical study with parallel group comparison. SETTING:Women's health clinical research unit at a universit...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究
doi：10.1016/j.fertnstert.2007.06.011
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVE:To describe three cases of azoospermia in patients with oligospermia after clomiphene citrate (CC) intake. DESIGN:Case report. SETTING(S):Academic medical center. PATIENT(S):Three patients with oligospermia. INTERVENTION(S):Three oligospermic men used CC, resulting in azoospermia. MAIN OUTCOME MEASURE(S)...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.03.036
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To compare the agonist flare-up and antagonist protocols in the management of poor responders to the standard long down-regulation protocol. DESIGN:Retrospective comparative study. SETTING:Assisted conception center. PATIENT(S):One hundred thirty-four patients undergoing IVF/ intracytoplasmic sperm injecti...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.07.963
更新日期：2005-02-01 00:00:00
abstract：OBJECTIVE:To report a successfully managed case of extensive intracranial sinus thrombosis that occurred during an IVF cycle, and to review the literature. DESIGN:Case report and review of literature. SETTING:University-affiliated teaching hospital. PATIENT(S):A 38-year-old nulliparous woman who developed severe ova...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.12.024
更新日期：2007-09-01 00:00:00
abstract：:Despite the introduction of new ovulation-inducing agents, CC remains the drug of choice for most anovulatory patients. Before initiating therapy, patients should be evaluated to determine the cause of anovulation. Patients with ovarian failure, hyperprolactinemia, hypothyroidism, or forms of CAH should be treated wit...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/s0015-0282(16)48129-x
更新日期：1984-10-01 00:00:00
abstract：OBJECTIVE:To review our experience with low-dose IM methotrexate for the medical management of ectopic pregnancy (EP). DESIGN:Retrospective chart review. SETTING:Magee-Womens Hospital, Pittsburgh, Pennsylvania. PATIENT(S):The first 50 women treated by the resident service in whom EP was diagnosed and treated with me...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)00284-7
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVE:To investigate the relative differences in outcomes among microdissection testicular sperm extraction (micro-TESE), conventional testicular sperm extraction (cTESE), and testicular sperm aspiration (TESA) in men with nonobstructive azoospermia. DESIGN:Systematic review and meta-analysis. SETTING:Outpatient ...
journal_title：Fertility and sterility
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.fertnstert.2015.07.1136
更新日期：2015-11-01 00:00:00
abstract：:Polyovular follicles were found in 61 (24%) of 251 laparoscopies performed for in vitro fertilization. Of 898 follicles that contained at least one oocyte, 76 (8%) were polyovular. When the oocytes from polyovular follicles were assessed by morphologic criteria, it was found that 46 of the follicles contained oocytes ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1988-03-01 00:00:00
abstract：OBJECTIVE:To investigate P secretion by granulosa cells (GCs) versus cumulus cells derived from human preovulatory follicles. DESIGN:Cells were recovered by aspiration of preovulatory follicles in 44 women participating in an IVF program. Induction of ovulation was performed using clomiphene citrate, hMG and hCG (grou...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)56404-8
更新日期：1993-12-01 00:00:00
abstract：:Nonaromatizable androgens, administered in high doses to an adult patient with partial androgen insensitivity, failed to result in a change in phallic size despite a clear decline in SHBG and gonadotropin levels. These findings raise the question of differential tissue sensitivity to androgens. Because ancillary labor...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)56114-7
更新日期：1993-08-01 00:00:00
abstract：:Two-cell mouse embryos were cultured in Ham's F-10 medium (Gibco, Grand Island, NY) supplemented with various concentrations of transferrin, insulin, epidermal growth factor, platelet-derived growth factor, or fibroblast growth factor. Rates of development and the cell numbers per blastocyst were compared between embr...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54082-5
更新日期：1991-01-01 00:00:00
abstract：:In contrast to a previous report by Krussel et al., with the inclusion of larger numbers of unfertilized oocytes and normal embryos and more sensitive immunofluorescence, this study shows that expression of vascular endothelial growth factor messenger ribonucleic acid can be detected from the oocyte to the blastocyst ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.11.047
更新日期：2006-06-01 00:00:00
abstract：:In the present study, we measured urinary hCG after assisted reproductive technology to accurately calculate normal doubling time (DT) of hCG, and we compared DT values with prognosis of pregnancy. We clarified the correlation between normal DT values, calculated from urinary hCG levels, and viable and nonviable pregn...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.03.066
更新日期：2005-10-01 00:00:00
abstract：:Danazol was found to possess androgenic and glucocorticoid activity in rat bioassays. In contrast, danazol displayed no significant estrogenic activity. In support of these findings, danazol bound to the 8 S androgen receptor of rat prostate cytosol and to the glucocorticoid receptor of rat liver cytosol, but danazol ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)43820-3
更新日期：1979-02-01 00:00:00
abstract：OBJECTIVE:To measure activin A concentrations in uterine washing fluid collected from women with couple infertility undergoing intrauterine insemination (IUI). DESIGN:Retrospective case-control study. SETTING:Tertiary university center for women's care. PATIENT(S):Fifty women, of whom 25 became pregnant after up to ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.12.125
更新日期：2010-05-01 00:00:00
abstract：OBJECTIVE:To demonstrate the feasibility of studying exosomes directly from peritoneal fluid, we isolated exosomes from endometriosis patient samples and from controls, and characterized their cargo. DESIGN:Case-control experimental study. SETTING:Academic clinical center. PATIENT (S):Women with and without endometr...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2019.09.032
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVE:To study the correlation between the incidence of sex chromosome aneuploidies in the somatic cells and spermatozoa in karyotypically normal infertile men and fertile donors. DESIGN:A prospective, phase two, controlled study. SETTING:A teaching Hospital Reproductive Medicine and Medical Genetics Units. PATI...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(00)00603-8
更新日期：2000-08-01 00:00:00
abstract：:Tissue integrity of the regurgitated endometrium is pivotal to the development of endometriosis. Occult, submicroscopic lesions occur. Diagnostic laparoscopy may underestimate as well as overestimate the presence of endometriosis. ...
journal_title：Fertility and sterility
pub_type： 评论,杂志文章,评审
doi：10.1016/j.fertnstert.2005.01.122
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVE:To develop molecular tools increasing the sensitivity of breast cancer micrometastases detection within ovarian tissue cryopreserved for fertility preservation. DESIGN:Expression of breast markers was evaluated by quantitative polymerase chain reaction in ovarian tissue from patients with benign or cancerous...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2015.04.036
更新日期：2015-08-01 00:00:00
abstract：OBJECTIVE:To analyze the effect of human papilloma virus (HPV) sperm infection on sperm parameters and in vitro fertilization (IVF) outcomes. DESIGN:Systematic review and meta-analysis. SETTING:Not applicable. PATIENTS:Men with HPV sperm infection and couples undergoing IVF. INTERVENTIONS:Searches were conducted in...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.01.010
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVE:To examine the relation between uterine blood flow and endometrial thickness on transvaginal Doppler ultrasonography, serum E2 and progesterone levels, and the histologic dating of an endometrial biopsy specimen obtained in the midluteal phase of a spontaneous cycle. DESIGN:Prospective clinical study. SETTI...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(99)00455-0
更新日期：2000-01-01 00:00:00
abstract：:To histologically and biologically assess the impairment of testicular function after active immunization with LH, adult male rats (49) and rabbits (9) were actively immunized with bovine LH and then compared with saline-injected controls. When the measured antibody titer was high, the mating behavior of the males wa...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)38046-3
更新日期：1971-02-01 00:00:00
abstract：OBJECTIVE:To describe the prevalence of antiphospholipid antibodies to both anionic and zwitterionic phospholipids in women with early recurrent pregnancy losses (RPLs). DESIGN:Retrospective data analysis. SETTING:Tokai University Hospital, Kanagawa, Japan. PATIENT(S):One hundred thirty-nine patients with unexplaine...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(99)00119-3
更新日期：1999-06-01 00:00:00
abstract：:Comparative studies have been carried out on the behavior of human and bovine spermatozoa toward homologous cervical mucus in vitro. In both cases the degree of sperm penetration and the pattern of sperm motility were influenced in a characteristic fashion by prior manipulation of the mucus: the most rapid and extensi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1980-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the effects of coital lubricants and oils on sperm motility. DESIGN:Comparative prospective in vitro study. SETTING:University Andrology laboratory. PATIENT(S):Twenty-two normozoospermic donors. INTERVENTION(S):Semen samples were incubated in modified human tubal fluid (mHTF) control and in 10...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.12.024
更新日期：2014-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the effects of endometriomas on the regulation of early follicular development. DESIGN:Histologic analysis of prospectively collected biopsy samples. SETTING:Research unit in a university hospital. PATIENT(S):Women <40 years of age who have ovarian endometriomas. INTERVENTION(S):Biopsy of heal...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.12.049
更新日期：2014-04-01 00:00:00
