Abstract:
:To examine the morphological evidence of the nature of hormone release from castration cells the author gonadectomized neonatal male and female rats. Twenty-eight days after the operation the animals were pretreated with estrogen, progesterone, or estrogen and progesterone in combination, every other day for one week, and then injected with LHRH 30 min before sacrifice. The administration of LHRH elevated remarkably the serum levels of gonadotrophins (LH and FSH) of neonatally gonadectomized rats. The steroid-pretreated animals showed higher serum levels of gonadotrophins than controls. Simultaneously, active exocytosis of secretory granules was observed in the hypertrophic gonadotrophs or castration cells of neonatally gonadectomized and steroid-treated rats following the injection of LHRH. These results indicate that hypertrophic gonadotrophs or castration cells also release hormone(s) by exocytosis of secretory granules.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Shiino Mdoi
10.1007/BF00218301subject
Has Abstractpub_date
1982-01-01 00:00:00pages
213-22issue
1eissn
0302-766Xissn
1432-0878journal_volume
222pub_type
杂志文章abstract::Osteogenic differentiation is a tightly regulated process realized by progenitor cell osteoblasts. Notch signaling pathway plays a critical role in skeletal development and bone remodeling. Controversial data exist regarding the role of Notch activation in promoting or preventing osteogenic differentiation. This study...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-019-03130-7
更新日期:2020-01-01 00:00:00
abstract::Communication between individuals is critical for species survival, reproduction, and expansion. Most terrestrial species, with the exception of humans who predominantly use vision and phonation to create their social network, rely on the detection and decoding of olfactory signals, which are widely known as pheromone...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-020-03376-6
更新日期:2021-01-12 00:00:00
abstract::The adrenal gland of mammals contains high concentrations of peripheral-type benzodiazepine receptors (PBR) and diazepam-binding inhibitor (DBI), a polypeptide which acts as an endogenous ligand for PBR. The aim of the present study was to investigate the localization of DBI and PBR in the adrenal gland of the frog Ra...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050551
更新日期:1996-03-01 00:00:00
abstract::The lobula descending neuron (LDN) of dipterous insects is a unique nerve cell (one on each side of the brain) that projects directly from the lobula complex of the optic lobes to neuropil in thoracic ganglia. In the supraoesophageal ganglia the LDN has two prominent groups of branches of which at least one is dendrit...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218365
更新日期:1982-01-01 00:00:00
abstract::The morphology and histology of the tibial auditory system of the New Zealand weta, Hemideina crassidens, are described. The groups of acoustic sensilla conform closely to the subgenual organ, intermediate organ and crista acoustica of the Tettigoniidae. Each prothoracic tibia bears two thick (40-100 micrometers) tymp...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233584
更新日期:1981-01-01 00:00:00
abstract::Previous investigations have demonstrated that peripheral insulin has a significant influence on brain function and that the interaction of insulin with neuropeptides in neuroendocrine regions may be pivotal for the regulation of body metabolism and energy balance. Since the various levels of interactions are only inc...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050833
更新日期:1997-06-01 00:00:00
abstract::Growth/differentiation factor-15 (Gdf-15) is a member of the transforming growth factor-β (Tgf-β) superfamily and has been shown to be a potent neurotrophic factor for midbrain dopaminergic (DAergic) neurons both in vitro and in vivo. Gdf-15 has also been shown to be involved in inflammatory processes. The aim of this...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-016-2406-x
更新日期:2016-08-01 00:00:00
abstract::Periodontal regeneration requires the coordinated movement and differentiation of several cell types in order to re-establish the cementum, periodontal ligament (PDL), and alveolar bone. Cells in culture are often used as model systems for mature tissues, although they may represent expanded progenitor cell population...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-006-0282-5
更新日期:2007-01-01 00:00:00
abstract::Captopril [1-(D-3-mercapto-2-methyl-1-oxopropyl)-L-proline (S,S)] is now known to be an inhibitor of angiotensin-converting enzyme. In male mice, the juxtaglomerular cells were examined by electron microscopy 42 h after administration of captopril. Numerous dense granules appeared in the rough endoplasmic reticulum of...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00209980
更新日期:1981-01-01 00:00:00
abstract::Seven isoforms of tachykinin-related peptides (TRPs) have been isolated from the brain of the cockroach Leucophaea maderae. These peptides (LemTRP-1, 2, and 5-9) share the C-terminal sequence GFX(1)GX(2)Ramide (where X(1) and X(2) are variable residues). In order to determine the neuronal distribution of several of th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0538-7
更新日期:2002-05-01 00:00:00
abstract::Lysozyme is one of the most prominent antimicrobial peptides and has been identified from many mammalian species. However, this enzyme has not been studied in the order Insectivora, which includes the most primitive placental mammals. Here, we done the lysozyme cDNA from Suncus murinus (referred to as suncus, its labo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-019-02991-2
更新日期:2019-06-01 00:00:00
abstract::Although cartilage is considered to be devoid of innervation, axons occur in the perichondrium and during development in cartilage canals, thereby having a relatively close spatial relationship to chondroblasts and chondrocytes. The present study locates the source of the sensory innervation of the femoral cartilagino...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004419900142
更新日期:2000-02-01 00:00:00
abstract::With the aid of electron microscopic immunocytochemistry following the application of antisera against somatostatin and luliberin (LRF), a labeling of the intercellular clefts in different areas of the brain was observed. This labeling is especially conspicuous near the basal pose of the cuboidal ependymal cells, but ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236448
更新日期:1980-01-01 00:00:00
abstract::Progenitor stem cells have been identified, isolated and characterized in numerous tissues and organs. However, their therapeutic potential and the use of these stem cells remain elusive except for a few progenitor cells from bone marrow, umbilical cord blood, eyes and dental pulp. The use of bone marrow-derived hemat...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-012-1471-z
更新日期:2012-10-01 00:00:00
abstract::Many efforts have been made to improve the diagnostic tools used to identify and to estimate the progress of ganglion cell and nerve fibre degeneration in glaucoma. Imaging by optical coherence tomography and measurements of the dimensions of the optic nerve head and the nerve fibre layer in central retinal areas is c...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-013-1602-1
更新日期:2013-08-01 00:00:00
abstract::The freshwater polyp Hydra magnipapillata has a primitive nervous system that produces at least three distinct classes of neuropeptides: various peptides having the C-terminal sequence Arg-Phe-NH2 (the Hydra-RFamide family), Leu-Trp-NH2 (the Hydra-LWamide family), and a single peptide having the C-terminal sequence Ly...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410000240
更新日期:2000-08-01 00:00:00
abstract::The secretory activity in the subcommissural organ (SCO) of the sheep and cow was examined by means of lectin histochemistry and cytochemistry. Among the various lectins tested. Concanavalin A (Con A) revealed glycoproteins rich in mannosyl residues in the rough endoplasmic reticulum of ependymal and hypendymal cells....
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222295
更新日期:1988-08-01 00:00:00
abstract::Some non-endocrine cells in the pituitary anterior lobe are responsible for providing stem/progenitor cells to maintain hormone-producing cells. In particular, cells expressing S100β protein, a calcium-binding protein, have been hypothesized to be a pituitary cell resource. Accumulating data have revealed that S100β-p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-014-1890-0
更新日期:2014-09-01 00:00:00
abstract::The termination of intrafusal muscle fibres was studied in muscle spindles of the tenuissimus muscle of the Chinese hamster. Most nuclear chain fibres terminated within the spindle capsule. The nuclear bag- and nuclear chain fibres that extended beyond the limit of the spindle capsule terminated in the endomysial conn...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218663
更新日期:1983-01-01 00:00:00
abstract::The therapeutic potency of delivered mesenchymal stem cells (MSCs) in tissue engineering applications may be improved by priming cells toward a differentiated state via coculture with native, differentiated cells prior to implantation; however, there is a lack of understanding in what may be the most efficacious metho...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-011-1265-8
更新日期:2012-03-01 00:00:00
abstract::Apart from the characteristic and progressive motor- and movement-related problems, Parkinson's disease (PD) patients also suffer from several non-motor symptoms, including gastrointestinal dysfunction. The fact that the enteric nervous system (ENS) controls motility and that one of the typical PD hallmarks, α-synucle...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-018-2856-4
更新日期:2018-07-01 00:00:00
abstract::The prolactin-producing cells are the first hormone-producing cells of the pars distalis to be differentiated within Ambystoma gracile. They first appear when the larvae attain a length of approximately 3.0 cm snout to vent length (SVL). Thyrotropes are observed as the next chromophilic cells to appear, and they occur...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00223121
更新日期:1978-05-18 00:00:00
abstract::Variations in gene expression patterns represent a powerful source of evolutionary innovation. In a rodent living about 70 million years ago, a genomic accident led an immune formyl peptide receptor (FPR) gene to hijack a vomeronasal receptor regulatory sequence. This gene shuffling event forced an immune pathogen sen...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03393-5
更新日期:2021-01-16 00:00:00
abstract::Antithrombin (AT), which is mainly synthesized in the liver, is an acute-phase plasma protein in mammalian species. Here, we demonstrated that sheep anti-human AT antibody cross-reacted with the humoral fluids in amphioxus Branchiostoma belcheri tsingtauense as well as human serum. The concentration of AT in the humor...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-005-0088-x
更新日期:2006-03-01 00:00:00
abstract::The haemomonochorial placenta of the guinea-pig undergoes several quantitative changes between the 49th and 64th days of gestation, all of which are in such a direction as to increase the efficiency of transplacental transport. The fetal vessels become larger, the maternal vessels increase in surface area by prolifera...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220974
更新日期:1977-11-23 00:00:00
abstract::Bone morphogenetic proteins (BMPs) induce cartilage and bone formation at both bony and non-bony sites. We examined the possibility whether BMP-2 induces differentiation of osteoblast progenitors into chondroblast lineage cells using organ culture and cell culture prepared from the calvaria of newborn mouse. BMP-2 sti...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050562
更新日期:1996-04-01 00:00:00
abstract::The effect of copulation on the rat coagulating gland (anterior prostate) was studied. At 4 to 6 h after the beginning of copulation the coagulating glands of rats that had produced copulatory plugs were nearly empty of secretion. Ultrastructurally, the coagulating gland has large cisternae of rough endoplasmic reticu...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221773
更新日期:1977-07-19 00:00:00
abstract::During developmental critical periods, external stimuli are crucial for information processing, acquisition of new functions or functional recovery after CNS damage. These phenomena depend on the capability of neurons to modify their functional properties and/or their connections, generally defined as "plasticity". Al...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-011-1293-4
更新日期:2012-07-01 00:00:00
abstract::We previously described the presence of MHC class II (HLA-DR) antigens, structurally similar to those on lymphoid cells and bearing the genetically-appropriate allotypic determinants, on human adrenocortical cells in the zona reticularis of normal glands. We now report a similar expression by granulosa-lutein cells (G...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00309876
更新日期:1990-11-01 00:00:00
abstract::By using an antiserum raised against a crustacean beta-pigment-dispersing hormone (PDH), the distribution and chemical neuroanatomy of PDH-like immunoreactive neurons was investigated in the central nervous system of the gastropod snails, Helix pomatia and Lymnaea stagnalis. The number of immunoreactive cells in the H...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051240
更新日期:1999-02-01 00:00:00