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Cell-substrate interaction. A method for evaluating the possible correlation between metastatic phenotype and cell surface energy.

Abstract：

:The interfacial energy of the non-attached to substrate cell surface was analysed in tumor cell variants of the K-1735 melanoma and UV-2237 fibrosarcoma series, which exhibit distinct metastatic phenotypes. The highly metastatic cell variants exhibited a two-fold increase in the ability to form rapid cell substrate interactions, as compared with their low-metastatic counterparts. These results further highlight the possible role of cell adhesiveness in the process of metastasis.

journal_name

Exp Cell Res

journal_title

Experimental cell research

authors

Reich S,Rosin H,Levy M,Karkash R,Raz A

doi

10.1016/0014-4827(84)90625-6

subject

Has Abstract

pub_date

1984-08-01 00:00:00

pages

556-60

issue

2

eissn

0014-4827

issn

1090-2422

journal_volume

153

pub_type

杂志文章

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