Abstract:
:[3H]-retinol binding to cellular retinol-binding protein (CRBP) increased more than five-fold in developing chicken corneal epithelium at 14 days of incubation, the time when the initial increase in corneal transparency occurs in the developing embryo. In contrast, [3H]-retinoic acid binding to cellular retinoic acid-binding protein (CRABP) was highest at the earliest stages and decreased progressively to a very low level in the corneal epithelium near the time of hatching. Thus, there appear to be changing and differing requirements for retinol and retinoic acid during development of the chicken cornea.
journal_name
Exp Eye Resjournal_title
Experimental eye researchauthors
Wiggert B,Masterson E,Coulombre AJdoi
10.1016/0014-4835(83)90026-xsubject
Has Abstractpub_date
1983-11-01 00:00:00pages
499-505issue
5eissn
0014-4835issn
1096-0007pii
0014-4835(83)90026-Xjournal_volume
37pub_type
杂志文章abstract::Eyes with age-related macular degeneration (AMD) demonstrate accumulation of specific deposits and extracellular matrix (ECM) molecules under the retinal pigment epithelium (RPE). AMD is about two times more prevalent in aging postmenopausal women. Therefore we studied whether 17beta-estradiol (E(2)) modulates the exp...
journal_title:Experimental eye research
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journal_title:Experimental eye research
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journal_title:Experimental eye research
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journal_title:Experimental eye research
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journal_title:Experimental eye research
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journal_title:Experimental eye research
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journal_title:Experimental eye research
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doi:10.1006/exer.1996.0194
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doi:10.1016/j.exer.2016.11.010
更新日期:2017-01-01 00:00:00
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journal_title:Experimental eye research
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doi:10.1006/exer.2000.0843
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journal_title:Experimental eye research
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更新日期:2019-10-01 00:00:00
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journal_title:Experimental eye research
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更新日期:2013-07-01 00:00:00
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更新日期:2006-09-01 00:00:00
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journal_title:Experimental eye research
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journal_title:Experimental eye research
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更新日期:2019-05-01 00:00:00
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journal_title:Experimental eye research
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