Forensic significance of postmortem estimation of the blood cerebrospinal fluid barrier permeability.

Abstract:

:Albumin concentration in cerebrospinal fluid (CSF) and plasma was determined in 44 cadavers divided into three groups on the basis of death agony duration. The same was determined in a control group of 42 patients with no demonstrable neurological disease. Following Schuller's method, the evaluation of the blood CSF barrier permeability was based upon the rate of albumin transfer from plasma to CSF. An average increase of 9% in blood CSF barrier permeability was found in cases of a long-duration death agony but not in cases of short-duration death agony (sudden deaths) or in the control group. We consider these results to be related to the hypoxia and hypercapnia which characterize the agonic suffering period. Therefore, we conclude that the postmortem determination of the rate of albumin transfer from plasma to CSF could be a reliable indicator of the duration of the agonic process.

journal_name

Forensic Sci Int

authors

Mangin P,Lugnier AA,Chaumont AJ,Offner M,Grucker M

doi

10.1016/0379-0738(83)90007-5

subject

Has Abstract

pub_date

1983-08-01 00:00:00

pages

143-9

issue

2-3

eissn

0379-0738

issn

1872-6283

pii

0379-0738(83)90007-5

journal_volume

22

pub_type

杂志文章
  • Experimental study of the coupling parameters influencing the terminal effects of thoracic blunt ballistic impacts.

    abstract::The objective of the study is to better understand how blunt projectile ballistic parameters and material properties influence the events leading to injuries. The present work focuses on lateral thoracic impacts and follows an experimental approach. The projectiles are made with a soft foam nose assembled with a rigid...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.04.004

    authors: Pavier J,Langlet A,Eches N,Prat N,Bailly P,Jacquet JF

    更新日期:2015-07-01 00:00:00

  • Simultaneous determination of pethidine (meperidine), phenoperidine, and norpethidine (normeperidine), their common metabolite, by gas chromatography with selective nitrogen detection.

    abstract::This article describes a selective gas chromatographic method for the resolution and quantification of phenoperidine and its two metabolites, pethidine (meperidine) and norpethidine (normeperidine). Drugs and SKF 525 A, the internal standard, are separated from plasma by solvent extraction under alkaline conditions. T...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(89)90154-0

    authors: Kintz P,Godelar B,Mangin P,Lugnier AA,Chaumont AJ

    更新日期:1989-12-01 00:00:00

  • Current defence strategies in some contested drink-drive prosecutions: Is it now time for some additional statutory assumptions?

    abstract::The prosecution of those socially irresponsible individuals who drive when they have had too much to drink - in that their breath, blood or urine alcohol level exceeds the prescribed legal limit - has been standard practice since October 1967. The forensic analysis of whichever type of specimen is taken from the suspe...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2018.09.030

    authors: Williams PM

    更新日期:2018-12-01 00:00:00

  • Osteometric sex discrimination from the sternal extremity of the fourth rib in a recent forensic sample from Southwestern Spain.

    abstract::The discrimination of sex is central to the process of establishing a personal identification from human skeletal remains. Previous study has demonstrated that osteometric analysis of the sternal extremity of the fourth rib provides a reasonably accurate method for assessing this biological attribute in diverse human ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2012.09.007

    authors: Macaluso PJ Jr,Rico A,Santos M,Lucena J

    更新日期:2012-11-30 00:00:00

  • Musculoskeletal stress marker (MSM) differences in the modern American upper limb and pectoral girdle in relation to activity level and body mass index (BMI).

    abstract::Obesity is a widespread condition affecting modern Americans. The prevalence of obesity has led to questions of how it can affect the skeleton, and if so can it be identified in unknown skeletal material. This study attempts to decipher the effects of activity level and body mass in modern Americans by employing muscu...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2011.03.014

    authors: Godde K,Taylor RW

    更新日期:2011-07-15 00:00:00

  • Drugged driving arrests in Norway before and after the implementation of per se law.

    abstract::Norway introduced legislative limits for driving under the influence of drugs (DUID) February 1st, 2012, to harmonize with the legislation on driving under the influence of alcohol. Per se limits corresponding to blood alcohol concentrations (BACs) of 0.02% were established for 20 drugs and concentration limits for gr...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2014.10.038

    authors: Vindenes V,Boix F,Koksæter P,Strand MC,Bachs L,Mørland J,Gjerde H

    更新日期:2014-12-01 00:00:00

  • Age estimation using a modified HPLC determination of ratio of aspartic acid in dentin.

    abstract::Diastereomeric dipeptides were derived from the amino acid enantiomers in dentin by O-phthalaldehyde-N-acetyl-L-cysteine. The products were separated using high performance liquid chromatography (HPLC) and detected by fluorescence detector. A short analysis time (total analysis time was 15 min, including retention tim...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(95)01709-7

    authors: Fu SJ,Fan CC,Song HW,Wei FQ

    更新日期:1995-05-09 00:00:00

  • Screening and determination of benzodiazepines in whole blood using solid-phase extraction and gas chromatography/mass spectrometry.

    abstract::Benzodiazepines are one of the most widely prescribed drugs for the treatment of a wide spectrum of clinical disorders. They are used as anticonvulsants, anxiolytics, hypnotics or muscle relaxants with different duration of action. In this paper, a simple and sensitive method for the determination of benzodiazepines i...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(00)00226-7

    authors: Inoue H,Maeno Y,Iwasa M,Matoba R,Nagao M

    更新日期:2000-09-11 00:00:00

  • DNA and RNA extraction from low amount of blood volume.

    abstract::Clinical and research-based tests in molecular biology require a substantial amount of DNA and RNA, unfortunately, a considerable number of cells is needed for this amount of sample. Blood is one of the best and easiest source of cells, but is not used due to its invasive drawing methods and the needed volume. Another...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2019.109931

    authors: Farivar S,Ghazimoradi MH

    更新日期:2019-10-01 00:00:00

  • Determination of the R- and S-enantiomers of methylone and ethylone in seized drugs by enantioselective liquid chromatography tandem mass spectrometry analysis.

    abstract::Synthetic cathinones constitute a major class of the new psychoactive substances (NPS) that have come to dominate recreational drug abuse in recent years. As synthetic cathinones are all chiral molecules, the use of chiral analysis to determine their enantiomeric ratios (ER) in seized drug samples can assist in the id...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2020.110528

    authors: Lin HR,Kuo FW

    更新日期:2020-12-01 00:00:00

  • Popliteal artery bullet embolism in a case of homicide: a case report and review of the tangible literature.

    abstract::Bullet embolism is a well known but a relatively rare phenomenon in common medicolegal autopsy practice. We present a homicide case of a bullet embolism to the left popliteal artery with interesting trajectory of projectile through the chest wall and right heart ventricle into the aortic lumen. Since in our presented ...

    journal_title:Forensic science international

    pub_type: 杂志文章,评审

    doi:10.1016/j.forsciint.2003.09.014

    authors: Slobodan S,Slobodan N,Djordje A

    更新日期:2004-01-06 00:00:00

  • The first report of Telomerina flavipes (Meigen, 1830) (Diptera, Sphaeroceridae) in a forensic case, with redescription of its pupa.

    abstract::This paper presents a forensic investigation that took place in the city of Murcia (SE Spain) and shows how the entomological specimens collected at the scene were extremely helpful for estimating the minimum post-mortem interval (PMImin). The occurrence of Telomerina flavipes (Meigen, 1830) (Diptera: Sphaeroceridae) ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2014.07.023

    authors: Arnaldos MI,Ubero-Pascal N,García R,Carles-Tolrá M,Presa JJ,García MD

    更新日期:2014-09-01 00:00:00

  • Rupture of an intracranial aneurysm--unusual complication of an electric shock.

    abstract::Here we report about a 35-year-old electrical engineer who was found dead in his study. Postmortem examination revealed that death resulted because of subarachnoid and intraventricular hemorrhage caused by the rupture of an intracranial aneurysm. Right hand and left cheek revealed electrical marks with metallizations ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(01)00475-3

    authors: Sprecher W,Wenz W,Haffner HT

    更新日期:2001-11-01 00:00:00

  • Differentiation between bruises and putrefactive discolorations of the skin by immunological analysis of glycophorin A.

    abstract::In a differential study to distinguish bruises from putrefactive discoloration, glycophorin A, a component of the erythrocyte membrane, was extracted from discolored skins and detected by immunological methods utilizing an anti-glycophorin A serum. Skin samples of 18 bruises, 8 postmortem hypostasises and 7 putrefacti...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(93)90219-z

    authors: Kibayashi K,Hamada K,Honjyo K,Tsunenari S

    更新日期:1993-10-01 00:00:00

  • Sodium monochloroacetate poisoning of greenfinches.

    abstract::A large number of passerine birds, mainly greenfinches, were found dead or dying in a hedgerow close to a field of onions recently sprayed with sodium monochloroacetate (SMCA). An analytical method is described for isolating monochloroacetic acid from bird tissues, as its potassium salt, by ion exchange chromatography...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(92)90075-8

    authors: Quick MP,Porter S,Bennett AC,Fleetwood AJ

    更新日期:1992-04-01 00:00:00

  • Levamisole-adulterated cocaine: Two fatal case reports and evaluation of possible cocaine toxicity potentiation.

    abstract::Levamisole has been identified as a cocaine adulterant in the United States since 2002. Although there is a variation in the percentage of levamisole in cocaine samples between European countries, measurement of levamisole in human samples of cocaine users has become increasingly important. To our best knowledge, only...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2016.01.005

    authors: Indorato F,Romano G,Barbera N

    更新日期:2016-08-01 00:00:00

  • Allele frequency distribution of four PCR-amplified loci in the Spanish population.

    abstract::The allele frequency distributions of four VNTR loci amplified by PCR have been studied in a population of 205 individuals from Spain. The loci analysed are D1S80 and three STRs: HUMTH01, HUMFES/FPS and HUMACTBF2 (SE33). The former was visualized in Metaphor agarose gels, and the STRs in sequencing polyacrylamide gels...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(94)01661-n

    authors: Cabrero C,Díez A,Valverde E,Carracedo A,Alemany J

    更新日期:1995-01-30 00:00:00

  • Comparison of practical techniques to develop latent fingermarks on fired and unfired cartridge cases.

    abstract::We have tested some widely used and practical fingermark enhancement techniques such as powdering (regular powder dusting and magnetic powder application), cyanoacrylate fuming, fluorescent dying (basic yellow 40), gun blueing solutions and acidified hydrogen peroxide solutions. The results were evaluated and compared...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.02.012

    authors: Girelli CM,Lobo BJ,Cunha AG,Freitas JC,Emmerich FG

    更新日期:2015-05-01 00:00:00

  • Effect of 1,2-indanedione on PCR-STR typing of fingerprints deposited on thermal and carbonless paper.

    abstract::1,2-Indanedione treated fingerprints deposited on two substrates (thermal and carbonless paper) were swabbed and tested to determine the effect of the chemical on PCR-STR DNA typing. Samples from 10 post-treatment intervals were analyzed. Two extraction methods, Chelex and Qiamp, were used to determine the effect of e...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2006.06.071

    authors: Yu PH,Wallace MM

    更新日期:2007-05-24 00:00:00

  • Insect fauna visiting carrion in Southwest Virginia.

    abstract::Successional patterns of insect fauna on pig carcasses were studied in southwest Virginia. The objective was to identify and qualitatively assess the major taxa of forensic importance in this region. Studies were conducted in spring and summer 2001 and 2002, and fall 2002. Over 50 taxa were collected and identified. P...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2004.06.041

    authors: Tabor KL,Fell RD,Brewster CC

    更新日期:2005-05-28 00:00:00

  • Genetic polymorphisms for 11 Y-STRs haplotypes of Chinese Yi ethnic minority group.

    abstract::Eleven Y-STRs loci including minimal haplotypes (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, and DYS385a,b) and two additional loci, namely DYS438 and DYS439 have been co-amplified in 100 healthy unrelated males of Chinese Yi minority ethnic group using the Y-PLEX 5 and Y-PLEX 6 kit, in order to investig...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2005.05.031

    authors: Zhu B,Shen C,Qian G,Shi R,Dang Y,Zhu J,Huang P,Xu Y,Zhao Q,Ma J,Liu Y

    更新日期:2006-05-10 00:00:00

  • Paraquat myopathy: report on two suicide cases.

    abstract::We describe two suicide cases in which old paraquat was ingested. In conjunction with lung involvement a pronounced degeneration was observed in skeletal muscle of one who died on the 14th day after the ingestion. The following sarcoplasmic or endoplasmic reticulum Ca2+ ATPase (SERCA) monoclonal antibodies were used f...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(98)00190-x

    authors: Tabata N,Morita M,Mimasaka S,Funayama M,Hagiwara T,Abe M

    更新日期:1999-03-15 00:00:00

  • STR data for the AmpFlSTR SGM Plus and Profiler loci from Taiwan.

    abstract::Allele frequencies for the 15 STRs included in the AmpFlSTR SGM Plus and Profiler kit (D3S1358, VWA, D16S539, D2S1338, D8S1179, D21S11, D18S51, D19S433, THO1, FGA, TPOX, CSF1PO, D5S818, D13S317 and D7S820) were obtained from a sample of 597 unrelated individuals living in Taiwan. All loci, except for D8S1179 and D5S81...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2003.09.006

    authors: Wang CW,Chen DP,Chen CY,Lu SC,Sun CF

    更新日期:2003-12-17 00:00:00

  • Identification of the potent toxin bongkrekic acid in a traditional African beverage linked to a fatal outbreak.

    abstract::In January 2015, 75 people died and 177 were hospitalized in the Mozambique village of Chitima after attending a funeral. The deaths were linked to the consumption of a traditional African beverage called pombe. Samples of the suspect pombe were subjected to myriad analyses and compared to a control sample. Ultimately...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2016.10.015

    authors: Falconer TM,Kern SE,Brzezinski JL,Turner JA,Boyd BL,Litzau JJ

    更新日期:2017-01-01 00:00:00

  • Shrunken head (tsantsa): a complete forensic analysis procedure.

    abstract::Based on the analysis of shrunken heads referred to our forensic laboratory for anthropological expertise, and data from both anthropological and medical literature, we propose a complete forensic procedure for the analysis of such pieces. A list of 14 original morphological criteria has been developed, based on the g...

    journal_title:Forensic science international

    pub_type: 历史文章,杂志文章

    doi:10.1016/j.forsciint.2012.06.009

    authors: Charlier P,Huynh-Charlier I,Brun L,Hervé C,de la Grandmaison GL

    更新日期:2012-10-10 00:00:00

  • Heteroplasmy in hair: differences among hair and blood from the same individuals are still a matter of debate.

    abstract::The analysis of mitochondrial DNA (mtDNA) is a useful tool in forensic cases when sample contents too little or degraded nuclear DNA to genotype by autosomal short tandem repeat (STR) loci, but it is especially useful when the only forensic evidence is a hair shaft. Several authors have related differences in mtDNA fr...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2007.02.011

    authors: Paneto GG,Martins JA,Longo LV,Pereira GA,Freschi A,Alvarenga VL,Chen B,Oliveira RN,Hirata MH,Cicarelli RM

    更新日期:2007-12-20 00:00:00

  • The analysis of quaternary ammonium compounds in human urine by direct inlet electron impact ionization mass spectrometry.

    abstract::An accurate and rapid screening test for nine quaternary ammonium compounds (suxamethonium chloride, pancuronium bromide, ambenonium chloride, benzethonium chloride, distigmine bromide, methylbenactyzium bromide, neostigmine bromide, propantheline bromide and pyridostigmine bromide) by direct inlet electron impact ion...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(91)90213-3

    authors: Nisikawa M,Tatsuno M,Suzuki S,Tsuchihashi H

    更新日期:1991-10-01 00:00:00

  • The use of serial measurement of plasma cholinesterase in the management of acute poisoning with organophosphates and carbamates.

    abstract:OBJECTIVE:To evaluate the benefits of using serial measurements of plasma cholinesterase (butyrylcholinesterase, BuChE) activity in the management of cholinesterase inhibitor insecticidal poisoning. METHOD:After establishing and validating BuChE activity test, and making it available for clinical service in the toxico...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2006.06.074

    authors: Abdullat IM,Battah AH,Hadidi KA

    更新日期:2006-10-16 00:00:00

  • Accuracy of developing tooth length as an estimate of age in human skeletal remains: the deciduous dentition.

    abstract::Dental age assessments are widely used to estimate age of immature skeletal remains. Most methods have relied on fractional stages of tooth emergence and formation, particularly of the permanent dentition, for predicting the age of infants and very young children. In this study, the accuracy of regression equations of...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2006.11.006

    authors: Cardoso HF

    更新日期:2007-10-02 00:00:00

  • Unreliable alcohol testing in a shipping safety programme.

    abstract:BACKGROUND:Within a maritime alcohol and drug testing programme, a case showing an unphysiological urine ethanol concentration (235 mmol/L, 10.8 g/L) was found. The sample contained low levels of the ethanol metabolites ethyl glucuronide (EtG) and ethyl sulphate (EtS) which confirmed prior drinking, but also tested pos...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2009.04.022

    authors: Helander A,Hagelberg CA,Beck O,Petrini B

    更新日期:2009-08-10 00:00:00