Abstract：
:The analysis of mitochondrial DNA (mtDNA) is a useful tool in forensic cases when sample contents too little or degraded nuclear DNA to genotype by autosomal short tandem repeat (STR) loci, but it is especially useful when the only forensic evidence is a hair shaft. Several authors have related differences in mtDNA from different tissues within the same individual, with high frequency of heteroplasmic variants in hair, as also in some other tissues. Is still a matter of debate how the differences influence the interpretation forensic protocols. One difference between two samples supposed to be originated from the same individual are related to an inconclusive result, but depending on the tissue and the position of the difference it should have a different interpretation, based on mutation-rate heterogeneity of mtDNA. In order to investigate it differences in the mtDNA control region from hair shafts and blood in our population, sequences from the hypervariable regions 1 and 2 (HV1 and HV2) from 100 Brazilian unrelated individuals were compared. The frequency of point heteroplasmy observed in hair was 10.5% by sequencing. Our study confirms the results related by other authors that concluded that small differences within tissues should be interpreted with caution especially when analyzing hair samples.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Paneto GG,Martins JA,Longo LV,Pereira GA,Freschi A,Alvarenga VL,Chen B,Oliveira RN,Hirata MH,Cicarelli RMdoi
10.1016/j.forsciint.2007.02.011subject
Has Abstractpub_date
2007-12-20 00:00:00pages
117-21issue
2-3eissn
0379-0738issn
1872-6283pii
S0379-0738(07)00096-5journal_volume
173pub_type
杂志文章abstract：:A total of 13 STR loci were typed from over 200 Caucasians from the Strathclyde region in the west of Scotland. ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(00)00317-0
更新日期：2001-02-15 00:00:00
abstract：BACKGROUND:Internationally, urine on-site testing has been used for detecting drivers under the influence of drugs (DUID) but more and more countries, such as Belgium, are switching to oral fluid screening. OBJECTIVE:To compare the previous (published in 1999) and current (published 2009) enforcement procedures of DUI...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2015.01.034
更新日期：2015-04-01 00:00:00
abstract：:A single nucleotide polymorphism (SNP) multiplex has been developed to analyse highly degraded and low copy number (LCN) DNA template, i.e. <100 pg, for scenarios including mass disaster identification. The multiplex consists of 20 autosomal non-coding loci plus Amelogenin for sex determination, amplified in a single ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2004.12.011
更新日期：2005-11-10 00:00:00
abstract：:To outline the recent features of methamphetamine-related fatalities from the medico-legal point of view, a retrospective investigation of forensic autopsy cases involving methamphetamine during a 5-year period (1994-1998) in the southern half of Osaka city and surrounding areas (about 1.57 million population) was und...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(00)00281-4
更新日期：2000-09-11 00:00:00
abstract：:During a stabbing, apparel fabrics are usually damaged and may be penetrated. Despite numerous studies considering forces required to penetrate skin and human stabbing performance, none have systematically evaluated which variables affect severance appearance from a textile science perspective using a human stabbing p...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2015.01.024
更新日期：2015-04-01 00:00:00
abstract：:The alarming increase of drug mortality rates in Germany was followed by research projects to enlighten the causes of this increase. The results of the Bremen, Hamburg and Berlin studies 1991-92, led to the conclusion that specific risk constellations have to be considered in the process of improving the drug counsell...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(93)90053-d
更新日期：1993-11-01 00:00:00
abstract：:Technology provides new ways to access customers and suppliers while enhancing the security of off-line criminal activity. Since the first cryptomarket, Silk Road, in 2011, cryptomarkets have transformed the traditional drug sale by facilitating the creation of a global network of vendors and buyers. Due to the fragme...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2018.05.002
更新日期：2018-07-01 00:00:00
abstract：:A urine screening in fatalities with an unnatural or unknown cause of death (13-40 years of age) was carried out to evaluate the proportion of undetected drug-related cases. Ten out of 160 fatalities without a hint of drug consumption were classified as drug-related according to the definition of the Bundeskriminalamt...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(93)90062-f
更新日期：1993-11-01 00:00:00
abstract：:Head hair samples obtained from surgery patients who received fentanyl during anesthesia were analyzed by immunoassay for the presence of fentanyl. Thirteen hair samples were collected from patients following intravenous administration of 1-6 mg of fentanyl. Additional hair samples were collected following the adminis...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(93)90250-e
更新日期：1993-09-01 00:00:00
abstract：:We study in this paper the expanding behaviour of hollow point 9 mm Parabellum projectiles (Hornady XTP(®) and Speer Gold Dot(®)). We defined a deformation rate that takes into account both the diameter increase and the length reduction. We plotted the behaviour of this parameter versus impact velocity (we refer to th...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2011.12.007
更新日期：2012-06-10 00:00:00
abstract：:Synthetic cannabinoids are a group of new psychoactive compounds (NPS) that act as agonists at the cannabinoid receptor. First reported in 2008, they currently represent one of the largest groups of NPS that are monitored by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). Five samples (4 from the...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2017.10.020
更新日期：2017-12-01 00:00:00
abstract：:In Australia, particularly Western Australia, there is a relative paucity of contemporary population-specific morphometric standards for the estimation of sex from unknown skeletal remains. This is largely a historical artefact from lacking, or poorly documented, repositories of human skeletons available for study. Ho...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2011.11.008
更新日期：2012-04-10 00:00:00
abstract：:As fatal trauma to the neck is often associated with short survival times, proof of vitality may often be difficult using standard histochemical techniques. Soft tissue neck injuries resulting from strangulation by ligature or manual strangulation were examined immunohistochemically using antibodies to myoglobin, fibr...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(03)00210-x
更新日期：2003-08-27 00:00:00
abstract：:Illicit cocaine samples (156), seized on Rome's illegal market between January 1996 and June 1997, were examined. Both the purity of the cocaine and the presence of substances employed for dilution were determined for each sample. Adulterants were found in many of the street samples analysed. Lidocaine (average 14.7%)...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(98)00102-9
更新日期：1998-08-12 00:00:00
abstract：:The examination of damage to a paper towel, an item of evidence in a murder case, is described. Simulations performed with selected tools and the observation of the lacerations present on the towel permitted to infer that they were originated by cleaning of a pointed and sharp implement. Some marks, considered charact...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2004.04.078
更新日期：2005-03-10 00:00:00
abstract：:A very serious case of DFSA (drug facilitated sexual assault) is presented, in which a six-year-old girl died following sedation with γ-hydroxybutyric acid (GHB). She had been sexually abused by a relative. Samples of cardiac blood, bile, vitreous humour, liver, kidney, brain tissues and hair were analysed by a LC-MS/...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2015.12.044
更新日期：2016-02-01 00:00:00
abstract：:This study determines the development rates of the immature stages of the fly Ophyra albuquerquei Lopes, 1985. In this study, with 70% relative humidity and a 12-h photophase, eggs, larvae, and pupae were kept in a biochemical oxygen demand chamber at temperatures of 10, 15, 17, 20, 22, 25, 27, 30, 33, 35, and 40°C. W...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2015.07.014
更新日期：2015-09-01 00:00:00
abstract：:As well as being the route for gaseous exchange, the nasal passages protect the lungs from debris and fine particulates inhaled during breathing. Foreign particles are trapped by mucus produced by membranes that line the upper respiratory tract. Even when a corpse has skeletonised, particles can be retrieved from the ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2005.11.019
更新日期：2006-11-22 00:00:00
abstract：:Forensic genetic genealogy, a technique leveraging new DNA capabilities and public genetic databases to identify suspects, raises specific considerations in a law enforcement context. Use of this technique requires consideration of its scientific and technical limitations, including the composition of current online d...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2020.110543
更新日期：2020-11-01 00:00:00
abstract：:The article is devoted to the comparative analysis of effectiveness of the most widely used methods for medico-legal examination of the hyoid bone and laryngeal cartilages, i.e. palpation, radiography and complete preparation. A consecutive study of 137 cases of hanging (including 20 cases of roentgenological analysis...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(97)00101-1
更新日期：1997-08-22 00:00:00
abstract：:The continuous emergence of NPS over the last years poses a series of novel challenges for forensic analysts. Most of those new compounds are synthesized with minimal chemical modifications to the structure of already known chemicals in order to avoid regulations. Some of these new compounds may undergo chemical chang...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2020.110306
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Studies testing the Willems method of age estimation with gender-specific scores on different population groups have reported consistently more accurate results over other methods. Not enough is known about the validity of Willems non-gender specific scores. AIM:The present study aimed to compare the accura...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2016.05.012
更新日期：2016-09-01 00:00:00
abstract：:Since 1985 several European Institutes of Forensic Medicine have cooperated in a multicenter study providing a constant monitoring of HIV-1 prevalence among drug-related deaths. From 1985 to 1991 the HIV status of 5372 drug-related fatalities (4328 males, 1044 females) has been tested. A total of 764 (14%) drug deaths...
journal_title：Forensic science international
pub_type： 杂志文章,多中心研究
doi：10.1016/0379-0738(93)90050-k
更新日期：1993-11-01 00:00:00
abstract：:In cases of criminal thallium poisoning, forensic investigation is required to identify the amount and time of thallium exposure. Usually, blood and urine thallium levels are respectively used as biomarkers. Additionally, hair has the unique potential to reveal retrospective information. Although several studies have ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2018.08.019
更新日期：2018-10-01 00:00:00
abstract：:The diffusion and trends in use of each substance is a basic information in policy planning of strategies aiming at deterrence of drug abuse or in the organization of the fight against drug trafficking. The actual diffusion of illicit drugs in a population is hardly measurable, but, among the various measures availabl...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2009.04.018
更新日期：2009-08-10 00:00:00
abstract：:General synthetic routes to 4-methyl-5-arylpyrimidines and 5-arylpyrimidines are described. 4-Benzylpyrimidine, 4-methyl-5-phenylpyrimidine, 4-(4-methoxybenzyl)pyrimidine, and 4-methyl-5-(4-methoxyphenyl)pyrimidine have been positively identified as route-specific by-products in the Leuckardt preparations of amphetami...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(00)00311-x
更新日期：2001-01-01 00:00:00
abstract：:In order to demonstrate the sequence diversity of mitochondrial D-loop DNA in the Taiwanese Han population, we established a database of 155 unrelated individuals. For each individual, the complete 980bp DNA region from the 5' end of HVI to 3' end of HVII segment was sequenced. In these 155 sequence data, 149 differen...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(00)00439-4
更新日期：2001-06-15 00:00:00
abstract：:The aim of the study was to describe victim, assailant, assault characteristics for sexual assault victims according to the time between the last sexual assault and the examination, and to provide descriptive data on medico-legal findings. The study was based on 418 examined victims of sexual assault during the year 1...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(02)00427-9
更新日期：2003-01-28 00:00:00
abstract：:When tried in court, mothers accused of neonaticide may claim that the umbilical cord just broke during birth and the newborn child bled to death accordingly. To evaluate the possibility of a breakage of the umbilical cord is the goal of this work. Therefore 25 umbilical cords from neonates of both sexes born at term ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2013.12.002
更新日期：2014-03-01 00:00:00
abstract：:In forensics and archaeology, it is important to distinguish human from animal remains and to identify animal species from fragmentary bones and bloodstains. We report blind tests in which a protein radioimmunoassay (pRIA) was used to identify the species of six bone fragments lacking morphological specificity and 43 ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2005.08.007
更新日期：2006-06-02 00:00:00
