The epilepsy of Fyodor Mikhailovitch Dostoevsky (1821-1881).

abstract：:Optogenetics is a novel technology that combines optics and genetics by optical control of microbial opsins, targeted to living cell membranes. The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton ...

journal_title：Epilepsia

authors： Mantoan Ritter L,Golshani P,Takahashi K,Dufour S,Valiante T,Kokaia M

更新日期：2014-11-01 00:00:00

abstract：:Infantile spasms begin in a very active phase of brain development. The new neuropathological techniques have shed light on changes in the fine structure of brain in children with infantile spasms. An understanding of the action of adrenocorticotropic hormone on the biochemistry and development of the brain provides, ...

journal_title：Epilepsia

authors： Riikonen R

更新日期：1983-04-01 00:00:00

abstract：:The clinical presentation of 366 children with rolandic spikes was examined to determine whether the presence of a temporal-frontal dipole field is associated with a lower incidence of clinical abnormality. Comparisons were made between the clinical presentation of 99 children with temporal-frontal dipole discharges v...

journal_title：Epilepsia

authors： Gregory DL,Wong PK

更新日期：1992-01-01 00:00:00

abstract：:The medical treatment of seizure disorders is a complex process, requiring extensive interaction and co-operation between physician and patient. The physician must have an accurate diagnosis of the patient's illness and a comprehensive understanding of seizures and seizure disorders. The physician must consider specif...

journal_title：Epilepsia

authors： Ferrendelli JA

更新日期：1995-01-01 00:00:00

abstract：:Accurate identification of cortical malformations in children with epilepsy can be crucial for successful clinical management. Although standard head-coil magnetic resonance imaging (MRI) at 1.5 tesla (T) can be used to view the macrostructure of the brain, phased array technology at both 1.5 and 3T significantly impr...

journal_title：Epilepsia

authors： Grant PE

更新日期：2005-01-01 00:00:00

abstract：PURPOSE:A prospective series of 643 persons with epilepsy attending a reference neurologic center in Medellín, Colombia, was examined by computed tomography (CT scan) or serology or both with the enzyme-linked immunoelectrotransfer blot assay (EITB) to assess the prevalence of Taenia solium cysticercosis. METHODS:All ...

journal_title：Epilepsia

authors： Palacio LG,Jiménez I,Garcia HH,Jiménez ME,Sánchez JL,Noh J,Ahn L,Mora O,Giraldo M,Tsang VC

更新日期：1998-12-01 00:00:00

abstract：:An understanding of the basic principles of human inheritance patterns is necessary to appreciate the variety and complexity of genetic influences in the epilepsies. The various modes of human inheritance include single gene (mendelian), chromosomal, mitochondrial, and multifactorial/polygenic. Recent insights regardi...

journal_title：Epilepsia

authors： Bird TD

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:Psychogenic nonepileptic seizures (PNES) are among the most common clinical manifestations of conversion disorder and consist of paroxysmal behavior that resembles epileptic seizures. Preliminary data from functional neuroimaging studies gave plausible evidence that limbic circuits and sensorimotor cortex might...

journal_title：Epilepsia

authors： Labate A,Cerasa A,Mula M,Mumoli L,Gioia MC,Aguglia U,Quattrone A,Gambardella A

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:To present new information on the semiology and short-term evolution of seizures associated with primary brain tumors (PBTs) in a prospective study. METHODS:This study is a section of the PERNO study--Project of Emilia Romagna Region on Neuro-Oncology, the main aim of which is to collect prospectively all case...

journal_title：Epilepsia

authors： Michelucci R,Pasini E,Meletti S,Fallica E,Rizzi R,Florindo I,Chiari A,Monetti C,Cremonini AM,Forlivesi S,Albani F,Baruzzi A,PERNO Study Group.

更新日期：2013-10-01 00:00:00

abstract：:We studied 47 consecutive patients who underwent temporal resection for seizure control. Nineteen (40%) had febrile convulsions preceding onset of their habitual seizures. In 17 of 18 patients whose disease duration was known, the febrile convulsions were prolonged (mean 4 h). As compared with patients without precedi...

journal_title：Epilepsia

authors： Abou-Khalil B,Andermann E,Andermann F,Olivier A,Quesney LF

更新日期：1993-09-01 00:00:00

abstract：:A multicenter prospective study was initiated at the time of first antiepileptic treatment for afebrile seizures with 283 unselected patients in Italy. Each patient started with monotherapy at standard daily doses. Data were collected at admission, at scheduled 6-month exams, and at unscheduled exams and included age,...

journal_title：Epilepsia

authors： Beghi E,Tognoni G

更新日期：1988-05-01 00:00:00

abstract：PURPOSE:To evaluate the effects of high-frequency electrical stimulation (HFS) in both ventral hippocampi, alone and combined with a subeffective dose of antiepileptic drugs, during the status epilepticus (SE) induced by lithium-pilocarpine (LP). METHODS:Male Wistar rats, stereotactically implanted in both ventral hip...

journal_title：Epilepsia

authors： Cuellar-Herrera M,Peña F,Alcantara-Gonzalez D,Neri-Bazan L,Rocha L

更新日期：2010-03-01 00:00:00

abstract：:Status epilepticus (SE) is associated with significant mortality and morbidity. A reliable prognosis may help better manage medical resources and treatment strategies. We examined the role of preexisting comorbidities on the outcome of patients with SE, an aspect that has received little attention to date. We prospect...

journal_title：Epilepsia

authors： Alvarez V,Januel JM,Burnand B,Rossetti AO

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To study the anticonvulsant effects of gabapentin (GBP) in immature animals. METHODS:Motor seizures were induced by pentylenetetrazol in 7-, 12-, 18-, 25-day-old, and adult rats. Animals pretreated with GBP (15, 30, or 60 mg/kg i.p.) were compared with controls. The incidence and latency of two types of seizur...

journal_title：Epilepsia

authors： Mares P,Haugvicová R

更新日期：1997-08-01 00:00:00

abstract：:Cortical malformations are highly epileptogenic lesions associated with complex, unanticipated, and often aberrant electrophysiologic and functional relationships. These relationships are inextricably linked to widespread cortical networks subserving eloquent functions, particularly language and motor ability. Cytomeg...

journal_title：Epilepsia

authors： Duchowny M

更新日期：2009-10-01 00:00:00

abstract：:We performed the blink reflex (BR) in 20 normal volunteers, 13 epileptic patients receiving antiepileptic drug (AED) monotherapy, and 13 epileptic patients receiving AED polytherapy. Comparison of R1, ipsilateral and contralateral R2 and VIIth nerve latencies in the three groups showed no statistically significant dif...

journal_title：Epilepsia

authors： Lancman ME,Cristiano E,Golimstok A,Granillo RJ

更新日期：1993-11-01 00:00:00

abstract：:The effect of short-term withdrawal of antiepileptic drugs (AEDs) on auditory event-related potentials (ERPs) was studied in 16 patients undergoing preoperative evaluation for epilepsy surgery. ERPs were performed for all patients during treatment with full medication and after a 1-week period during ongoing tapering ...

journal_title：Epilepsia

authors： Tuunainen A,Nousiainen U,Pilke A,Mervaala E,Riekkinen P

更新日期：1995-03-01 00:00:00

abstract：:Seventy-eight patients with temporal lobe type seizures were precisely matched for age, sex, and Wechsler I.Q. levels with patients suffering from other seizure types. Statistically significant differences were established between the groups in regard to treatment response, etiologies, and behavioral variables. Furthe...

journal_title：Epilepsia

authors： Rodin EA,Katz M,Lennox K

更新日期：1976-09-01 00:00:00

abstract：PURPOSE:This study examined the relation between psychiatric diagnosis and mental health services in children with epilepsy and the associated demographic, cognitive, linguistic, behavioral, and seizure-related variables. METHODS:The Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS), the Child Behavio...

journal_title：Epilepsia

authors： Ott D,Siddarth P,Gurbani S,Koh S,Tournay A,Shields WD,Caplan R

更新日期：2003-04-01 00:00:00

abstract：:The vagus is a mixed nerve carrying somatic and visceral afferents and efferents. The majority of vagal nerve fibers are visceral afferents and have a wide distribution throughout the central nervous system (CNS) either monosynaptically or via the nucleus of the solitary tract. Besides activation of well-defined refle...

journal_title：Epilepsia

authors： Rutecki P

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:The predictive value of intraoperative electrocorticography (ECoG) in pediatric epilepsy surgery is unknown. In a population of children undergoing ECoG followed typically by invasive extraoperative monitoring (IEM) and resection, we aimed to determine the relationship between frequent ECoG abnormalities and ...

journal_title：Epilepsia

authors： Greiner HM,Horn PS,Tenney JR,Arya R,Jain SV,Holland KD,Leach JL,Miles L,Rose DF,Fujiwara H,Mangano FT

更新日期：2016-04-01 00:00:00

abstract：:The success of surgery for seizure focus resection depends on postoperative reduction or disappearance in number of seizures, improvement in psychosocial functioning, and low morbidity and mortality. Permanent neurologic sequelae are most often not discussed in this context. Deficits more than a superior quadrantanops...

journal_title：Epilepsia

authors： Helgason CM,Bergen D,Bleck TP,Morrell F,Whisler W

更新日期：1987-07-01 00:00:00

abstract：PURPOSE:In a previous investigation (Lah et al., 2004), we found deficits in retrograde memory in patients who had undergone temporal lobectomy (TL). In this study, we set out to determine whether such deficits are present before surgery in patients with temporal lobe epilepsy (TLE). METHODS:Memory for public and auto...

journal_title：Epilepsia

authors： Lah S,Lee T,Grayson S,Miller L

更新日期：2006-03-01 00:00:00

abstract：:A recent systematic synthesis of qualitative research demonstrated that patients with psychogenic nonepileptic seizures (PNES) often experience unsatisfactory encounters with health care practitioners (HCPs). It is important to understand such interactions from the perspective of those responsible for delivering care....

journal_title：Epilepsia

authors： Rawlings GH,Reuber M

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:Assumptions regarding the benefits of seizure control after pediatric epilepsy surgery for cognitive, psychosocial, and family function were explored in a prospective study of 51 children with intractable epilepsy. METHODS:Thirty children who underwent surgery were studied before and 1 year after surgery, and ...

journal_title：Epilepsia

authors： Smith ML,Elliott IM,Lach L

更新日期：2004-06-01 00:00:00

abstract：PURPOSE:To estimate magnetoencephalography (MEG) correlates of different types of aura in temporal lobe epilepsy (TLE). METHODS:MEG study was performed on 57 patients (26 male and 31 female) with TLE, whose ages ranged from 14-46 years (mean 27 years). Interictal magnetoencephalograms showing discharges were analyzed,...

journal_title：Epilepsia

authors： Fukao K,Inoue Y,Yagi K

更新日期：2010-09-01 00:00:00

abstract：:The randomized, double-blind trial design offers the most accurate data regarding the efficacy of antiepileptic treatments. However, translating the results of a trial into clinical care can be complex due to the intrinsic tension between the requirements for scientific methods that minimize systematic and random erro...

journal_title：Epilepsia

authors： Gilliam F

更新日期：2003-01-01 00:00:00

abstract：:Epilepsy Bereaved? is a charity that aims to inform, support, and empower partners, relatives, and friends of people affected by sudden unexpected death in epilepsy (SUDEP). It also works toward preventing mortality due to SUDEP through raising awareness and promoting research. The aim of Epilepsy Bereaved? is to enab...

journal_title：Epilepsia

authors： Hanna J

更新日期：1997-11-01 00:00:00

abstract：PURPOSE:To determine whether methsuximide (MSM) affects lamotrigine (LTG) blood levels and whether any change is of clinical significance. METHODS:LTG serum levels in 16 patients taking MSM were compared with those before starting or after stopping the MSM. The 16 patients, (11 boys, five girls) were young people (mea...

journal_title：Epilepsia

authors： Besag FM,Berry DJ,Pool F

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVES:Health-related quality of life (HRQOL) is an important indicator of well-being in patients with epilepsy. When assessing changes in HRQOL over time, some of the changes observed may be due to the patients' change in the internal standards, value, or meaning that they attribute to the HRQOL domain being measu...

journal_title：Epilepsia

authors： Sajobi TT,Fiest KM,Wiebe S

更新日期：2014-09-01 00:00:00