Abstract:
:Infantile spasms begin in a very active phase of brain development. The new neuropathological techniques have shed light on changes in the fine structure of brain in children with infantile spasms. An understanding of the action of adrenocorticotropic hormone on the biochemistry and development of the brain provides, in an indirect way, a partial explanation of the biochemical events in this syndrome; most of these actions are well documented in animal experiments. Some anticonvulsants are also effective in treating infantile spasms, and modern research has explained many actions of these agents as well. The principal mechanism causing retardation in most children is unknown. Some future aspects of the research are reviewed.
journal_name
Epilepsiajournal_title
Epilepsiaauthors
Riikonen Rdoi
10.1111/j.1528-1157.1983.tb04875.xsubject
Has Abstractpub_date
1983-04-01 00:00:00pages
159-68issue
2eissn
0013-9580issn
1528-1167journal_volume
24pub_type
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