Abstract:
:The emergency treatment of seizures is an important practical issue, especially the treatment of generalized convulsive status epilepticus (GCSE). Benzodiazepines or older standard antiepileptic drugs (phenobarbital, phenytoin) have typically been used as initial intravenous treatment of GCSE. As new parenteral antiepileptic drugs are developed, and more are on the horizon, questions are raised regarding their role in the treatment of status epilepticus (SE). This review discusses the evidence for the treatment of GCSE, including the newer agents (valproate, levetiracetam). We correlate the treatment of SE with our modern understanding of the underlying neurophysiology and seizure duration.
journal_name
Epilepsiajournal_title
Epilepsiaauthors
Wheless JW,Treiman DMdoi
10.1111/j.1528-1167.2008.01929.xsubject
Has Abstractpub_date
2008-12-01 00:00:00pages
74-8eissn
0013-9580issn
1528-1167pii
EPI1929journal_volume
49 Suppl 9pub_type
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