Chorea and polycythaemia.

abstract：:The role of genetics in Parkinson's disease (PD), previously controversial, is now supported by several studies. A major breakthrough has been the discovery of a single gene defect in familial Parkinson's disease. A single base pair change at position 209 from G to A (G209A) in the fourth exon of the alpha-synuclein g...

journal_title：European neurology

authors： Hu CJ,Sung SM,Liu H,Chang JG

更新日期：1999-01-01 00:00:00

abstract：:There is good evidence that patients with Parkinson's disease have respiratory chain dysfunction in their substantia nigra. Since mitochondrial cytopathies due to enzyme defects in the respiratory chain are predominantly manifested in tissues with a high oxidative metabolism we analyzed oxidative energy metabolism in ...

journal_title：European neurology

authors： Reichmann H,Janetzky B,Bischof F,Seibel P,Schöls L,Kuhn W,Przuntek H

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND/AIMS:We prospectively assessed the frequency, type, severity and cause of treatment among the long-term residents of the Kork Epilepsy Centre in the year 2005. METHODS:All long-term residents were exclusively referred to the general surgeon practicing on the campus. Patients were divided into 2 groups compr...

journal_title：European neurology

authors： Steinhoff BJ,Hartmann R,Luy M,Rombach A,Ziegler G,Schulte-Mönting J,Gilliam FG

更新日期：2010-01-01 00:00:00

abstract：:The hypothesis that mitochondrial genes may implicate susceptibility to multiple sclerosis (MS) is supported by an increasing number of case reports on Leber's hereditary optic neuropathy (LHON)-associated mitochondrial DNA (mtDNA) point mutations in patients with MS. A number of mtDNA mutations with primary pathogeni...

journal_title：European neurology

authors： Houshmand M,Sanati MH,Rashedi I,Sharifpanah F,Asghari E,Lotfi J

更新日期：2004-01-01 00:00:00

abstract：:L-Dopa pioneered the symptomatic therapy of Parkinson's disease. While this treatment proved effective in the treatment of parkinsonian akinesia, rigidity and tremor, prolonged L-dopa treatment was often noted to result in dyskinesia, psychosis and 'on-off' phenomena. This increasing disability of L-Dopa-treated parki...

journal_title：European neurology

authors： Kuno S

更新日期：1994-01-01 00:00:00

abstract：:A case of thoracic hematomyelia secondary to anticoagulant therapy is presented. Clinical features, similar to 2 other previously reported cases, are discussed. A high index of suspicion may lead to a quick diagnostic procedure and successful decompressive surgery. ...

journal_title：European neurology

authors： Constantini S,Ashkenazi E,Shoshan Y,Israel Z,Umansky F

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND/AIMS:Newer Scandinavian data on intracerebral hemorrhage (ICH) are scarce. We aimed at providing updated community-based data on the incidence, characteristics and outcome of ICH leading to hospitalization in the southernmost region in Norway. METHODS:We analyzed data from all consecutive patients hospitali...

journal_title：European neurology

authors： Tveiten A,Ljøstad U,Mygland A,Thomassen L,Pripp AH,Naess H

更新日期：2012-01-01 00:00:00

abstract：:Mitochondrial abnormalities and effectiveness of replacement therapy were examined in a murine model of systemic carnitine deficiency, namely the juvenile visceral steatosis (JVS) mouse. Homozygous JVS mice revealed severe lipid deposition and abnormal mitochondria in liver, heart, skeletal muscle, and kidney, but the...

journal_title：European neurology

authors： Kaido M,Fujimura H,Ono A,Toyooka K,Yoshikawa H,Nishimura T,Ozaki K,Narama I,Kuwajima M

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Several testing options are available to detect asymptomatic coronary artery disease (CAD). Dobutamine stress echocardiography (DSE) has been reported to increase the sensitivity and specificity of stress testing to detect CAD. Most studies concerned patients with known or suspected CAD who have a high prete...

journal_title：European neurology

authors： Nighoghossian N,Cakmak S,Derex L,Barthelet M,Thibault H,Finet G,Ovize M,Derumeaux G,Nemoz C,Chapuis F,Rioufol G

更新日期：2006-01-01 00:00:00

abstract：:70 cases of multiple sclerosis were seen at the Department of Neurology of the Capital Hospital in 1949--1977. There were 25 males and 45 females averaging 30.6 years of age. The most frequent sites of the lesions based on the clinical symptomatology were the spinal cord and optic nerve, the cerebellum was much less f...

journal_title：European neurology

authors： Zhao BX,Liu XQ,Guo YP,Yang YC,Huang HF

更新日期：1981-01-01 00:00:00

abstract：:Morphological findings of 3 cases of Kaeser's scapulo-peroneal muscular atrophy are described. 1 of them is the first complete autopsy report on this disease. While the number of motor neurons in the spinal cord was grossly normal, the neuropil of the anterior horn exhibited axonal swellings, accumulations of possibly...

journal_title：European neurology

authors： Probst A,Ulrich J,Kaeser HE,Heitz P

更新日期：1977-01-01 00:00:00

abstract：:Current treatment options for restless legs syndrome (RLS), based on the American Academy of Sleep Medicine practice parameters, favor dopaminergic agents. The drug of first choice is levodopa, which is now licensed for RLS in two European countries. However, the short duration of action and augmentation of symptoms u...

journal_title：European neurology

authors： Stiasny K

更新日期：2001-01-01 00:00:00

abstract：:Changes in the maximal rate of some cerebral enzymatic activities related to 400ene transduction and neurotransmission (lactate dehydrogenase; citrate synthase and malate dehydrogenase; total NADH-cytochrome c reductase and cytochrome oxidase; glutamate dehydrogenase; acetylcholine esterase) were assayed both in the c...

journal_title：European neurology

authors： Villa RF

更新日期：1981-01-01 00:00:00

abstract：:A case of post-convulsive spinal spidural haematoma in a patient with ankylosing spondylitis is presented. As acute tetraplegia developed, surgery was performed with finding of blood clots in the extradural space from C6 to D8. Lethal evolution due to late referral to medical care stresses the need for prompt decompre...

journal_title：European neurology

authors： Agnetti V,Monaco F,Mutani R

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND/AIMS:Behavioral and psychological symptoms of dementia (BPSD) affect almost all people with dementia at some stage during the progression of disease. The current study aimed at replicating previous findings on BPSD clustering in behavioral sub-syndromes. METHODS:One hundred and sixty-six consecutive outpati...

journal_title：European neurology

authors： Poletti M,Nuti A,Cipriani G,Bonuccelli U

更新日期：2013-01-01 00:00:00

abstract：:We examined interleukin-2 (IL-2) production by phytohemagglutinin (PHA)-stimulated peripheral blood mononuclear cells (PBMs) from 75 untreated myasthenia gravis (MG) patients and 48 control patients. Patients with MG consisted of those with elevated PBM IL-2 production (>1,250 pg/ml; mean + 2SD of the controls) (n = 2...

journal_title：European neurology

authors： Utsugisawa K,Nagane Y,Obara D,Kondoh R,Yonezawa H,Tohgi H

更新日期：2003-01-01 00:00:00

abstract：:MPTP, 1-methyl-4-phenyl-pyridinium ion (MPP+) and the structurally related compounds including N-methyltetrahydroisoquinilinium ion inhibited the tyrosine hydroxylase (TH) system in tissue slices of rat striatum at 10(-5) M. Mouse striatum is more susceptible to MPTP than rat striatum. A similar degree of inhibition b...

journal_title：European neurology

authors： Nagatsu T,Hirata Y

更新日期：1987-01-01 00:00:00

abstract：:A case of Guillain-Barré syndrome (GBS) in a young patient who suffered from an acute cytomegalovirus (CMV) infection is presented. The diagnosis was reached following the isolation of the virus from the urine and the demonstration of high titers of both IgM and IgG antibodies in the serum. In contrast to previous cas...

journal_title：European neurology

authors： Mozes B,Pines A,Sayar Y,Kaplinsky N,Frankl O

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Tetrahydrocannabinol:cannabidiol (THC:CBD) oromucosal spray (Sativex®) is an add-on therapy for moderate-to-severe multiple sclerosis (MS)-related drug-resistant spasticity (MSS). AIM:The MOVE-2 EU study collected data from everyday clinical practice concerning the effectiveness and tolerability of THC:CBD....

journal_title：European neurology

authors： Vermersch P,Trojano M

更新日期：2016-01-01 00:00:00

abstract：:We report a laser microprobe mass analysis of aluminum and iron content in the hippocampus and in the inferior temporal cortex in 2 cases of dementia pugilistica (DP), 4 cases of Alzheimer's disease (AD), and 3 controls. There was a predominant accumulation of Al and Fe within neurofibrillary tangles (NFT) in both DP ...

journal_title：European neurology

authors： Bouras C,Giannakopoulos P,Good PF,Hsu A,Hof PR,Perl DP

更新日期：1997-01-01 00:00:00

abstract：:The case of an 8-year-old boy presenting diffuse, prevalently right-sided nevus flammeus, venous angioma of the right cerebral hemisphere, right-sided facial hyperplasia, lef-handedness and recurring strokes is reported together with the clinical, angiographic and CT features. ...

journal_title：European neurology

authors： Tomaccini D,Venturi C,Scarfò GB

更新日期：1981-01-01 00:00:00

abstract：:We examined 29 patients with chronic progressive ganglionopathy of different etiology. Neurophysiological abnormalities were dominated by a widespread decrease in sensory nerve action potential amplitudes, which involved both upper and lower limb nerves, even in patients with asymmetrical or patchy clinical presentati...

journal_title：European neurology

authors： Lauria G,Pareyson D,Sghirlanzoni A

更新日期：2003-01-01 00:00:00

abstract：:The consequences of cerebral infarcts involving the left hemisphere differ from those of the right homologue areas. Data of 337 consecutive, unselected patients with acute ischaemic stroke in the territory of the right or left middle cerebral artery were analysed. Furthermore, lesion locations of 77 stroke patients wi...

journal_title：European neurology

authors： Aszalós Z,Barsi P,Vitrai J,Nagy Z

更新日期：2002-01-01 00:00:00

abstract：:An HIV-positive patient presented the classical syndrome of pure alexia. Neuroradiologic investigation by computed tomography showed a ring-like lesion in the left posterior white matter. The clinical manifestations as well as the radiologic findings resolved after antiprotozoal treatment. ...

journal_title：European neurology

authors： Lüscher C,Horber FF

更新日期：1992-01-01 00:00:00

abstract：:To elucidate the clinical characteristics of aged patients with Becker muscular dystrophy (BMD), 4 patients with this disease who were over 50 years were examined. The ages at onset in all patients were later than 30 years. All were proven to have a deletion around exons 45-55 of the Duchenne muscular dystrophy (DMD) ...

journal_title：European neurology

authors： Yazaki M,Yoshida K,Nakamura A,Koyama J,Nanba T,Ohori N,Ikeda S

更新日期：1999-01-01 00:00:00

abstract：:We describe a case presenting continuous muscle fiber activity syndrome, which was slightly reduced by the blocking of nerve conduction and abolished by ischemia. Clinical, electromyographical and bioptical evidence of marked abnormalities of peripheral motoneurons were observed. Association with central motoneuron le...

journal_title：European neurology

authors： Cotrufo R,Di Iorio G,Ammendola A,Bravaccio F

更新日期：1982-01-01 00:00:00

abstract：:Thirty-three headache-free patients (19 F/14 M) suffering from common (n = 9) and classic migraine (n = 19) as well as cluster headache (n = 5) were investigated using the flow tracer 99mTc-hexamethyl propylenamino oxime and single photon emmission computed tomography. A regional decrease of cerebral tracer uptake was...

journal_title：European neurology

authors： Schlake HP,Böttger IG,Grotemeyer KH,Husstedt IW,Vollet B,Schober O,Brune GG

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:To evaluate the role of some sex hormones in migraine headaches, the aim of this study was to assess the prevalence and characteristics of headache, especially migraine, in patients with polycystic ovary syndrome (PCO) compared with women without this disease. METHODS:One hundred and thirty-three women with...

journal_title：European neurology

authors： Pourabolghasem S,Najmi S,Arami MA

更新日期：2009-01-01 00:00:00

abstract：:This study investigated the maximum number of collaterals that can be maintained by 1 axon during regeneration of rat peripheral nerve. The tibial nerve was transected, the proximal residual, with its variable number of axons, was fixed to the distal stump and served as the donor nerve. The number of myelinated axons ...

journal_title：European neurology

authors： Jiang BG,Yin XF,Zhang DY,Fu ZG,Zhang HB

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:The diagnosis of Guillain-Barre syndrome (GBS) in the very early stage may be challenging. Our aim was to report the neurophysiological abnormalities in GBS within 4 days of clinical onset. We expected that GBS will be diagnosed by the assistance of neurophysiological study in the very early stage. METHODS:We ...

journal_title：European neurology

authors： Jin J,Hu F,Qin X,Liu X,Li M,Dang Y,Dang J

更新日期：2018-01-01 00:00:00