Abstract:
:Soil samples were collected from the ground under the plants of Euphorbiaceae and Thymelaeaceae known to possess Epstein-Barr virus-activating diterpene esters. In a test system, the ether extracts of such soil samples at a concentration of 20 micrograms/ml induced Epstein-Barr virus early antigen in approximately 5-25% of the non-producer Raji cells. These findings suggest a possible interaction between plant-derived diterpene esters and the human system, and provide a new aspect in considering the cause of Epstein-Barr virus-associated diseases, particularly nasopharyngeal carcinoma.
journal_name
Cancer Lettjournal_title
Cancer lettersauthors
Ito Y,Ohigashi H,Koshimizu K,Yi Zdoi
10.1016/0304-3835(83)90144-1subject
Has Abstractpub_date
1983-06-01 00:00:00pages
113-7issue
2eissn
0304-3835issn
1872-7980pii
0304-3835(83)90144-1journal_volume
19pub_type
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