Abstract:
:The fine structure of the ventrolateral and dorsomedial subdivisions of the ventromedial nucleus (VMN) of the hypothalamus was examined in ovariectomized/control and ovariectomized/estrogen-treated rats to compare neurons of these areas to other neurons (specifically the ventrolateral thalamus), and to determine the effects of estrogen on these cells. The neurons of the VMN contain a large nucleus with a prominent nucleolus, rough endoplasmic reticulum (RER), polysomes, a Golgi complex, coated, uncoated and dense-cored vesicles, lysosome-like bodies, inclusion bodies, multivesicular bodies whorl bodies and myelin figures. Similar organelles were present in the neurons of the ventrolateral thalamus, although polysomes wee more prominent, and the cells lacked dense-cored vesicles in the perikarya. Differences in the cells of the VMN between ovariectomized/control and ovariectomized/estrogen-treated rats included a more conspicuous stacking of the RER and greater number of dense-cored vesicles in the estrogen-treated group in both the ventrolateral and dorsomedial subdivisions. In both areas the differences were statistically significant, although more marked in the ventrolateral subdivision. In both VMN subdivisions, the increased stacking of the RER could be correlated with the greater number of dense-cored vesicles and may reflect increased biosynthesis of a secretory product.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Cohen RS,Pfaff DWdoi
10.1007/BF00219357subject
Has Abstractpub_date
1981-01-01 00:00:00pages
451-70issue
3eissn
0302-766Xissn
1432-0878journal_volume
217pub_type
杂志文章abstract::Vesicular transport involves SNARE (soluble- N-ethylmaleimide-sensitive-factor-attachment-protein-receptor) proteins on transport vesicles and on target membranes. Syntaxin 13 is a SNARE enriched in brain, associated with recycling endosomes; its overexpression in PC12 cells promotes neurite outgrowth. This suggests a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0600-5
更新日期:2002-08-01 00:00:00
abstract::Interstitial cells in the myenteric plexus and the deep muscular plexus of the small intestine of the c-kit mutant rats (Ws/Ws) and their normal siblings (+/+) were studied. c-Kit immunoreactivity was detected in two regions corresponding to the myenteric plexus and the deep muscular plexus in the jejunum of +/+ rats,...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051119
更新日期:1998-08-01 00:00:00
abstract::The epithelial surface of the taste disc on the fungiform papillae of the frog was studied by means of freeze-fracture and conventional electron microscopy. The plasma membrane of the apical process of taste receptor cells was found to exhibit a uniform population of 10-nm intramembrane particles on its fracture face ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216883
更新日期:1982-01-01 00:00:00
abstract::Among heterogeneous S100β-protein-positive (S100β-positive) cells, star-like cells with extended cytoplasmic processes, the so-called folliculo-stellate cells, envelop hormone-producing cells or interconnect homophilically in the anterior pituitary. S100β-positive cells are known, from immunohistochemistry, to emerge ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-015-2256-y
更新日期:2016-02-01 00:00:00
abstract::The adrenal gland of mammals contains high concentrations of peripheral-type benzodiazepine receptors (PBR) and diazepam-binding inhibitor (DBI), a polypeptide which acts as an endogenous ligand for PBR. The aim of the present study was to investigate the localization of DBI and PBR in the adrenal gland of the frog Ra...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050551
更新日期:1996-03-01 00:00:00
abstract::The ultrastructure of the dermal papulae of a starfish (Asterias rubens) is consistent with a respiratory function. The present study has shown no regions specialized for excretory mechanisms. The papulae consist of an outer ectodermal epithelium of sensory, support and gland cells and a small basiepithelial nerve ple...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00229616
更新日期:1978-03-13 00:00:00
abstract::Some non-endocrine cells in the pituitary anterior lobe are responsible for providing stem/progenitor cells to maintain hormone-producing cells. In particular, cells expressing S100β protein, a calcium-binding protein, have been hypothesized to be a pituitary cell resource. Accumulating data have revealed that S100β-p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-014-1890-0
更新日期:2014-09-01 00:00:00
abstract::Spermatozoa from the cauda epididymidis of gossypol-treated rats exhibit distinctive departures from the morphology of spermatozoa from control rats: wrinkled and disorganized cell membrane in the head and tail regions, cell membrane missing from segments of the tail midpiece and principal piece regions, malformed hea...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00210003
更新日期:1981-01-01 00:00:00
abstract::The H-Tx rat has fetal-onset hydrocephalus associated with closure of the cerebral aqueduct and a reduction in the secretory cells of the subcommissural organ (SCO), a circumventricular organ situated in the dorsal wall of the cerebral aqueduct. The objective of this study was to determine the role of the SCO in hydro...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-003-0843-9
更新日期:2004-03-01 00:00:00
abstract::The protein synthesis inhibitor cycloheximide (Chx) suppresses prolactin-induced beta-casein gene expression in the mammary epithelial cell line COMMA-D. As the mechanism underlying this effect is unclear, the effects of protein synthesis inhibitors on interactions of transcription factors with the beta-casein promote...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0672-2
更新日期:2003-02-01 00:00:00
abstract::Gastrin stimulates gastric acid secretion by acting on the cholecystokinin B/gastrin receptor (CCK-BR). The localization of this receptor at the cellular level showed conflicting results in animal studies and has not been described in man by immunohistochemistry. The aim of the present study is to characterize the pre...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004419900114
更新日期:2000-02-01 00:00:00
abstract::Coincident with an increase in the water permeability of toad urinary bladder induced by serosal hypertonicity, a transformation of the ridge-like surface structures of the granular cells into individual microvillous structures occurs. This study was initiated to establish whether the transformation is mediated by the...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217226
更新日期:1984-01-01 00:00:00
abstract::Spinal cord injury (SCI) is a major cause of paralysis, disability and even death in severe cases. Lithium has neuroprotective effects on SCI, while the underlying mechanisms remain obscure. In the present study, we established a SCI rat model, which subsequently received lithium treatment. Results displayed that lith...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03298-3
更新日期:2021-01-19 00:00:00
abstract::The spatial and temporal distribution of three peptides, DSK I, DSK II, and DSK 0, encoded by the Drosophila melanogaster drosulfakinin (Dsk) gene, have been examined in the central nervous system. DSK I and DSK II have a -RFamide C-terminus and are structurally similar to sulfakinin peptides; in contrast, DSK 0 conta...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050518
更新日期:1996-01-01 00:00:00
abstract::Activities of the H+, K(+)-ATPase and the Na+, K+, ATPase have been localized in the morphologically heterogeneous oxyntic cell lineage of adult bovine abomasal mucosa, by means of K(+)-dependent paranitrophenylphosphatase (K(+)-pNPPase) histochemistry. At the light- and electron-microscopic level, only members of the...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050583
更新日期:1996-05-01 00:00:00
abstract::During amphibian intestinal remodeling, thyroid hormone (TH) induces some larval epithelial cells to dedifferentiate into adult stem cells, which newly generate the absorptive epithelium analogous to the mammalian epithelium. To clarify molecular mechanisms underlying adult epithelial development, we here focus on TH ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-016-2396-8
更新日期:2016-08-01 00:00:00
abstract::In this study, we focus on the specific contribution of β integrin-like protein to adhesion-mediated events in molluscan larval cells in culture that could not have been investigated within the whole animal. An analysis of disturbances to cell-substratum adhesion, caused by the integrin receptor inhibiting Arg-Gly-Asp...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-015-2122-y
更新日期:2015-08-01 00:00:00
abstract::Germ cells of human fetuses aged 7-13 weeks were studied. Dense fibrous material called nuage was found in the cytoplasm of human fetal germ cells. The nuage increased in frequency in the germ cells during the interval studied. In oogonia the nuage occurred much more frequently than in spermatogonia and the frequency ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00209243
更新日期:1978-11-09 00:00:00
abstract::Biocytin, recently introduced in neuroanatomical studies, was used as a retrograde tract tracer in combination with immunofluorescence in order to analyse the neurochemical characters of some central neuronal projections to the pars intermedia in two amphibian species, the anuran Rana esculenta and the urodele Trituru...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050754
更新日期:1997-02-01 00:00:00
abstract::The periodontal ligament (PDL) is a highly specialized tissue connecting the cementum with the tooth socket bone and affects the life span of the tooth. However, little is known about the precise characteristics and regenerative mechanism of PDL cells because of the absence of specific markers and cell lines. Therefor...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-005-0101-4
更新日期:2006-04-01 00:00:00
abstract::The ultrastructure of the sinus gland of the fiddler crab, Uca pugnax, was investigated and found to be similar to that in other crustaceans. Five types of neurosecretory axon terminals were tentatively identified on the basis of the size, shape, and electron density of granules within the axons. Release of neuro-secr...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222805
更新日期:1975-12-29 00:00:00
abstract::Teleost fish exhibit extraordinary cognitive skills that are comparable to those of mammals and birds. Kin recognition based on olfactory and visual imprinting requires neuronal circuits that were assumed to be necessarily dependent on the interaction of mammalian amygdala, hippocampus, and isocortex, the latter being...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-020-03378-4
更新日期:2021-01-30 00:00:00
abstract::Although the secretory products of the hypothalamo-neurohypophyseal system are not glycoproteins, synthesis and migration of these macromolecules occur within its secretory neurons. After being labeled with 3H-fucose in the Golgi apparatus, newly synthesized glycoproteins migrate to secretion granules, lysosomes and t...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234755
更新日期:1980-01-01 00:00:00
abstract::The distribution of endocrine cells in the gastrointestinal tract of the house musk shrew, Suncus murinus (Family Soricidae, Order Insectivora) was studied immunohistochemically. The hormones investigated were gastrin, cholecystokinin (CCK), somatostatin, secretin, glucagon, gastric inhibitory polypeptide (GIP), motil...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00239456
更新日期:1989-11-01 00:00:00
abstract::The surface coat of the electrocyte of the main electric organ of Electrophorus electricus was studied using cytochemical methods (periodic acid-silver methanamine, periodic acid-chromic acid-silver methenamine, periodic acid-thiosemicarbazide-silver proteinate, Concanavalin A - horseradish peroxidase, ruthenium red, ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00226622
更新日期:1977-09-26 00:00:00
abstract::The ultrastructure of the isolated glycerinated penis retractor muscle (PRM) of Helix pomatia was investigated. The diameter distributions of thick myofilaments from birbre cross sections in the relaxed, phasic contracted, tonic contracted, and in the catch state.s show that a characteristic filament spectrum is forme...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221808
更新日期:1975-01-01 00:00:00
abstract::Hepatic peroxisomes in human embryos with a menstrual age of 6 and 7 weeks have been examined via catalase cytochemistry. In the younger sample, the organelles show no catalase activity, their matrix being pale and coarsely reticular. In the 7-week specimen, the peroxisome population consists of catalase-positive and ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00323574
更新日期:1993-04-01 00:00:00
abstract::The distribution of MAP2 and actin in dendritic spines of the visual and cerebellar cortices, dentate fascia, and hippocampus was determined by using immunogold electron microscopy. By this approach, we have confirmed the presence of MAP2 in dendritic spines and identified substructures within the spine compartment sh...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00225592
更新日期:1989-06-01 00:00:00
abstract::The retina of the phalangid, Opilio ravennae, consists of retinula cells with distal rhabdomeres, arhabdomeric cells, and sheath cells. The receptive segment of retinula cells shows a clear separation into a proximal rhabdom, organized into distinct rhabdom units formed by three or four retinula cells, and a distal rh...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233658
更新日期:1979-01-01 00:00:00
abstract::Dysfunction of the retinal pigmented epithelium (RPE) is one of the first effects of dry age-related macular degeneration (AMD) with consequent blindness. Hence, patients affected by this retinal disorder could benefit from a cell-based transplantation strategy for RPE. Actually, an effective protocol to approach this...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-015-2185-9
更新日期:2015-10-01 00:00:00