Abstract：
:We extracted from L. biflexa patoc a fraction F, reacting in hemagglutination and ring tests with sera prepared against more than ten different serogroups. This fraction contains mainly a polysaccharide (65 per cent), the role of which was clearly demonstrated in the precipitation reaction with homologous antisera, through periodic oxidation; it also contains lipids (20 per cent) and proteins (10 per cent). We isolated from this fraction F, by Biogel column chromatography, 2 distinct antigens, one, F2, carrying the patoc-type specificity, the other, F 1B, a group specificity shared by many leptospira. These antigens differ not only immunogically, but also in their chemical composition. The type-specific antigen F2 contains mainly a polysaccharide composed of arabinose and glucosamine (possibly an immunodominant sugar). As for the group-specific fraction F 1B, its composition is more complex since lipids and proteins are also found with the polysaccharide. This antigen could therefore be a lipoglycoprotein.
journal_name
Biochimiejournal_title
Biochimieauthors
Gabay J,Tinelli Rdoi
10.1016/s0300-9084(76)80313-6subject
Has Abstractpub_date
1976-01-01 00:00:00pages
827-35issue
7eissn
0300-9084issn
1638-6183pii
S0300-9084(76)80313-6journal_volume
58pub_type
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