Prurigo nodularis: a reappraisal of the clinical and histologic features.

abstract：BACKGROUND:Pemphigoides gestationis (PG) is a blistering disorder of pregnancy caused by antibodies against basement membrane proteins. They are directed against the 180 kD bullous pemphigoid antigen (BPAg2), towards the epitopes within the NC 16A domain. There are many similarities between pemphigoid gestationis and b...

journal_title：Journal of cutaneous pathology

authors： Patton T,Plunkett RW,Beutner EH,Deng JS,Jukic DM

更新日期：2006-04-01 00:00:00

abstract：:We present the case of a 28-year-old male with a history of human immunodeficiency virus (HIV) with a 1-month history of a steadily enlarging, firm painful lesion on the right posterior shoulder. The patient was initially treated for cellulitis given his clinical picture. Histopathologic examination revealed an angioc...

journal_title：Journal of cutaneous pathology

authors： Malviya N,Rainwater YB,Vandergriff T,Mauskar MM

更新日期：2017-03-01 00:00:00

abstract：:The skin biopsy specimens from six patients with primary mixed IgM-IgG cryoglobulinemia were examined by immunofluorescence, light and electron microscopy. The biopsy taken from the involved skin of one patient with leg ulcers revealed small blood vessel occlusions by cryoglobulin aggregates. Since a similar finding w...

journal_title：Journal of cutaneous pathology

authors： Berliner S,Weinberger A,Ben-Bassat M,Idesess C,Hazaz B,David M,Pinkhas J

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Among the pigmented lesions with a central area of scar, we found a group of cases histologically characterized by striking architectural alteration of the melanocytic component, but with no cytological atypia and mitotically quiescent. The aim of the current study was to assess the biological nature of such...

journal_title：Journal of cutaneous pathology

authors： Fabrizi G,Pennacchia I,Pagliarello C,Massi G

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:The lack of highly specific clinical and histopathological criteria has contributed to the delay in diagnosis of subungual melanoma in situ in its early stages. METHODS:Eighteen cases of subungual melanoma in situ, the largest series reported to date, were analyzed to characterize the clinical and histopath...

journal_title：Journal of cutaneous pathology

authors： Park SW,Jang KT,Lee JH,Park JH,Kwon GY,Mun GH,Lee DY,Lee JB,Park KK

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Cutaneous tumor metastasis may be the first manifestation of cancer, but more often is a harbinger of advanced disease that portends an ominous prognosis. All skin accessions over the past 10 years from a large Veterans Administration (VA) hospital were reviewed. METHODS:Archived histories, glass slides, an...

journal_title：Journal of cutaneous pathology

authors： Saeed S,Keehn CA,Morgan MB

更新日期：2004-07-01 00:00:00

abstract：:Light and electron-microscopic studies were performed on the amelanotic and adjacent normal-appearing skin in patients with vitiligo. The amelanotic skin revealed complete loss of pigment and absence of melanocytes. In addition to severe degenerative changes of melanocytes, varying degree of damage was also seen in th...

journal_title：Journal of cutaneous pathology

authors： Bhawan J,Bhutani LK

更新日期：1983-06-01 00:00:00

abstract：:The distribution of desmoglein, plakoglobin, E-cadherin, and beta-catenin in the peri-lesional and lesional skin of Hailey-Hailey disease, Darier's disease, and pemphigus vulgaris was examined by immunoelectron microscopy. In the peri-lesional skin, the immunolabeling of these desmosomal components was localized to de...

journal_title：Journal of cutaneous pathology

authors： Tada J,Hashimoto K

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) represent 2 entities that cause primary cicatricial alopecia. These entities are clinically different; nevertheless, the literature suggests that FFA represents a form of LPP. The main argument in support of this hypothesis is that previous studi...

journal_title：Journal of cutaneous pathology

authors： Gálvez-Canseco A,Sperling L

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Gene expression profiling of melanoma and nevic tissue has demonstrated that pleiotrophin (PTN) is significantly overexpressed in human melanomas. METHODS:To further evaluate PTN expression in melanocytic lesions, protein immunohistochemistry was performed on the spectrum of melanocytic lesions. RESULTS:Me...

journal_title：Journal of cutaneous pathology

authors： Wu H,Barusevicius A,Babb J,Klein-Szanto A,Godwin A,Elenitsas R,Gelfand JM,Lessin S,Seykora JT

更新日期：2005-02-01 00:00:00

abstract：:Fifteen halo nevi were stained for the presence of S100 protein by an unlabelled antibody peroxidase-antiperoxidase method. S100 protein was clearly identifiable within nevus cell nests in the inflammatory infiltrate. The presence of this substance helped to identify nevus cells in dense inflammatory infiltrates and c...

journal_title：Journal of cutaneous pathology

authors： Penneys NS,Mayoral F,Barnhill R,Ziegels-Weissman J,Nadji M

更新日期：1985-02-01 00:00:00

abstract：:Post-vaccinial non-viral folliculitis has been recognized in the past decade as a new adverse cutaneous reaction to smallpox vaccination. Contrary to more serious smallpox vaccine reactions, post-vaccinial non-viral folliculitis has a benign course and resolves spontaneously within approximately 7 days. We describe ad...

journal_title：Journal of cutaneous pathology

authors： Bunick CG,Mariwalla K,Ibrahim O,Modi B,Imaeda S,McNiff JM

更新日期：2013-03-01 00:00:00

abstract：:Extraskeletal Ewing's sarcoma has been recognized as being histologically indistinguishable from Ewing's sarcoma of bone. Although the occurrence of extraosseous Ewing's sarcoma in deep soft tissues has been well described, such cutaneous lesions are rare. We report the clinical history, histopathologic findings, and ...

journal_title：Journal of cutaneous pathology

authors： Peters MS,Reiman HM,Muller SA

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Although skin carcinogenesis has been widely investigated, only limited information is available for epidermal tumors, while even less is known about other skin structures. Alterations in the β-catenin pathway have been reported in several epidermal tumors, while little is known about in adnexal tumors. This...

journal_title：Journal of cutaneous pathology

authors： Im M,Kim DH,Park JS,Chung H,Lee Y,Kim CD,Seo YJ,Lee JH

更新日期：2011-08-01 00:00:00

abstract：:A 35-year-old woman was examined because of a symptomless multiple annular eruption. The lesion consisted of rings of closely set, smooth, firm papules that were brown in color. Hemosiderotic histiocytoma was diagnosed by light and electron microscopy. Ultrastructurally, the lesion consisted of fibroblastic and histio...

journal_title：Journal of cutaneous pathology

authors： Saga K

更新日期：1981-06-01 00:00:00

abstract：:Two collodion baby girls with disorder evolving into lamellar ichthyosis were followed by light and electron microscopy. Light microscopically, the neonatal colloidion skin was characterized by a thick compact stratum corneum which was PAS positive in its upper two thirds, by a thin stratum granulosum and by a non-aca...

journal_title：Journal of cutaneous pathology

authors： Frenk E,Mevorah B

更新日期：1977-12-01 00:00:00

abstract：:Although CD1a+ dendritic cells (DC) in cutaneous T-cell lymphomas (CTCL) have been well documented, the presence of large numbers of DC within lymphoid infiltrates can pose a diagnostic difficulty. We present a case of a 70-year-old man with a 3-year history of recurrent red papules and plaques on the extremities and ...

journal_title：Journal of cutaneous pathology

authors： Jokinen CH,Wolgamot GM,Wood BL,Olerud J,Argenyi ZB

更新日期：2007-07-01 00:00:00

abstract：:Facial inflammatory dermatoses can be difficult to diagnose in their early stages; skin biopsy may help but often shows indeterminate features. The aims of our study were to identify patients presenting with a facial dermatosis requiring skin biopsy, in whom the initial histological features were classified as "non-sp...

journal_title：Journal of cutaneous pathology

authors： Rhodes LE,Parslew RA,Ashworth J

更新日期：1995-04-01 00:00:00

abstract：:CD44 is a widely distributed cell surface protein thought to be involved in multiple steps of normal immune cell function, including T-cell activation, and in cellular adhesion where it mediates cell attachment to hyaluronate. In normal skin, CD44 is found by immunohistochemical means to be primarily in eccrine coil c...

journal_title：Journal of cutaneous pathology

authors： Sawaya ME,Bakshandeh H,Hordinsky MK,Penneys NS

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Cutaneous lymphatic malformations represent a group of heterogeneous diseases caused by developmental defects of lymphatic system. OBJECTIVE:The purpose of this study was to report the clinical, histopathological and immunohistochemical features of a distinctive lymphatic malformation. METHODS:Twelve patie...

journal_title：Journal of cutaneous pathology

authors： Wang L,Gao T,Wang G

更新日期：2013-07-01 00:00:00

abstract：:A malignant pilomatricoma is described in a dog. The primary tumor apparently developed in the metatarsal area where there were multiple intradermal skin nodules. Lymphatic invasion by tumor cells resulted in metastasis to the mammary glands, lymph nodes and lungs. The tumor is compared to the pilomatricoma in man whe...

journal_title：Journal of cutaneous pathology

authors： Goldschmidt MH,Thrall DE,Jeglum KA,Everett JI,Wood MG

更新日期：1981-10-01 00:00:00

abstract：:A 24-year-old black woman from Uganda was seen for treatment of multiple papules on her hands and feet. The lesions corresponded microscopically to foci of hyperkeratosis and acanthosis. Acid orcein stain revealed marked elastic fiber fragmentation. Acrokeratoelastoidosis of Costa (AKE) was diagnosed. The same damage ...

journal_title：Journal of cutaneous pathology

authors： Fiallo P,Pesce C,Brusasco A,Nunzi E

更新日期：1998-11-01 00:00:00

abstract：:A 46-year-old man had a cystic mass on the right side of his scalp. Histological examination revealed a cystic dermal nodule composed of relatively circumscribed lobules of proliferating squamous epithelium, with atypical mitoses and dyskeratotic cells of invasive structure, which was diagnosed as proliferating tricho...

journal_title：Journal of cutaneous pathology

authors： Masui Y,Komine M,Kadono T,Ishiura N,Maekawa T,Ihn H,Kikuchi K,Tamaki K

更新日期：2008-10-01 00:00:00

abstract：:We report a case of a 68-year-old man with cutaneous leiomyosarcoma of the penis. Leiomyosarcoma of the penis is an extremely rare neoplasm that usually presents in middle to old age, and to our knowledge only approximately 30 cases have been reported in the literature to date. This is an important diagnosis in the di...

journal_title：Journal of cutaneous pathology

authors： Cibull TL,Thomas AB,Badve S,Billings SD

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Fatty acid synthase (FAS), the key enzyme responsible for the synthesis of fatty acids, is weakly expressed in some normal human tissues. Recently, FAS has been demonstrated to be overexpressed in many non-neoplastic highly proliferative lesions and in aggressive carcinomas with poor outcome, including colon...

journal_title：Journal of cutaneous pathology

authors： Innocenzi D,Alò PL,Balzani A,Sebastiani V,Silipo V,La Torre G,Ricciardi G,Bosman C,Calvieri S

更新日期：2003-01-01 00:00:00

abstract：:Confocal laser scanning microscopy (CLSM) is a new optical microscopic technique, which offers significant advantages over conventional microscopy. CLSM is microscopy of optical sections. Light, which is emitted from regions other than the focal plane, is cut off by introducing a diaphragm in the beam path. The result...

journal_title：Journal of cutaneous pathology

authors： Fink-Puches R,Hofmann-Wellenhof R,Smolle J,Kerl H

更新日期：1995-06-01 00:00:00

abstract：:Palisaded encapsulated neuroma (PEN; solitary circumscribed neuroma) is a benign, morphologically characteristic cutaneous or mucosal neuroma. Most are solitary lesions on the face, neck or oral mucosa. Histologically, the majority appears as dermal nodules of Schwann cell-rich fascicles, with or without distinctive e...

journal_title：Journal of cutaneous pathology

authors： Jokinen CH,Ragsdale BD,Argenyi ZB

更新日期：2010-01-01 00:00:00

abstract：:We have previously shown that human metallopanstimulin (MPS-1) is a ubiquitous 9.4-kDa multifunctional ribosomal S27/nuclear "zinc finger" protein which is expressed at high levels in a wide variety of cultured proliferating cells and tumor tissues, including melanoma. In the present study, we have examined the expres...

journal_title：Journal of cutaneous pathology

authors： Santa Cruz DJ,Hamilton PD,Klos DJ,Fernandez-Pol JA

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Melanocytic nevi from the genitalia are uncommon. Nevi on the vulva are much better described than nevi on male genitalia. To our knowledge, a systematic study of preputial melanocytic nevi has not been reported. OBJECTIVE:To investigate the frequency of clinically unapparent melanocytic nevi on a series of...

journal_title：Journal of cutaneous pathology

authors： Val-Bernal JF,Val D,Garijo MF

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:p16 immunostaining has been used to aid and improve the histopathologic evaluation of equivocal cervical lesions with associated low-grade or high-grade dysplasia. However, the utility of p16 immunostaining in the diagnosis of atypical genital skin lesions remains debatable. METHODS:We conducted a cross-sec...

journal_title：Journal of cutaneous pathology

authors： Ezaldein H,Lott JP,McNiff JM,Hui P,Buza N,Ko CJ

更新日期：2015-08-01 00:00:00