Keratinocyte damage in vitiligo.

abstract：:Melanoma ex blue nevus (MEBN) is a rare, aggressive, and potentially lethal neoplasm. Distinguishing MEBN from an atypical cellular blue nevus can be very challenging. We report a diagnostically difficult case of MEBN with lymph node metastases, in which single nucleotide polymorphism array and fluorescence in situ hy...

journal_title：Journal of cutaneous pathology

authors： Castillo SA,Pham AK,Barton DT,Lefferts JA,Yan S,Bridge JA,Linos K

更新日期：2019-03-01 00:00:00

abstract：:Nevic corpuscle in the pigmented nevus was studied under light microscopy in comparison with Meissner corpuscle of the human sole skin in order to determine its ontogenesis. No nerve fibers within nevic corpuscle but coiled fibers in Meissner corpuscle could be demonstrated by Bodian stain. Presence of S-100 protein i...

journal_title：Journal of cutaneous pathology

authors： Sueki H,Iwai M,Kato H,Nishida H

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Ulceration and osteoclast-like giant cells are two pathological features uncommonly seen in dermatofibromas. To our knowledge, the presence of these features has not been previously described within the same lesion. METHODS:We report the clinical, histopathological and immunohistochemical findings of a 38-y...

journal_title：Journal of cutaneous pathology

authors： González-Vilas D,García-Gavín J,Ginarte M,Rodríguez-Blanco I,Toribio J

更新日期：2009-10-01 00:00:00

abstract：:Infundibulocystic basal cell carcinoma (IBCC) is a relatively recently described variant of basal cell carcinoma that is controversial and not universally accepted. Excluding cases of nevoid basal cell carcinoma syndrome, IBCC usually presents as a small, solitary, superficial lesion on the face of older persons. Ther...

journal_title：Journal of cutaneous pathology

authors： Kagen MH,Hirsch RJ,Chu P,McCormack PC,Weinberg JM

更新日期：2000-07-01 00:00:00

abstract：:Atypical fibroxanthoma (AFX) is an uncommon cutaneous neoplasm of pleomorphic myofibroblast-like cells. Diagnosis requires exclusion of other undifferentiated spindle and pleomorphic cell neoplasms by immunohistochemistry. We report two patients with p63-non-reactive spindle cell neoplasms which resembled AFX but demo...

journal_title：Journal of cutaneous pathology

authors： Ellis R,Chase E,Barland A,Rajpara A,Fraga GR

更新日期：2015-11-01 00:00:00

abstract：:Immunohistochemical properties were studied in 16 lesions from 11 patients with chordoma involving the skin. There were nine men and two women ranging from 21 to 62 years old (mean, 42.6). The initial tumor was sacrococcygeal in 10 cases and nasopharyngeal in 1 case. Three lesions represented a direct extension from t...

journal_title：Journal of cutaneous pathology

authors： Gagné EJ,Su WP

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Some examples of Bowen disease lack the characteristic broad parakeratosis making their histopathologic diagnosis particularly difficult in small and incomplete biopsies. MATERIALS AND METHODS:The archives of our dermatopathology laboratory were searched for cases of Bowen disease with >75% orthokeratosis (...

journal_title：Journal of cutaneous pathology

authors： Idriss MH,Misri R,Böer-Auer A

更新日期：2016-01-01 00:00:00

abstract：:Lobular capillary hemangioma, which is also named as pyogenic granuloma, is a common vascular proliferation of skin and mucous membranes. Hormonal influence in the development of lobular capillary hemangioma on the mucosal surfaces has been demonstrated but for cutaneous lesions located on the skin, this association h...

journal_title：Journal of cutaneous pathology

authors： Demir Y,Demir S,Aktepe F

更新日期：2004-01-01 00:00:00

abstract：:Perifollicular fibroma is a cutaneous hamartomatous proliferation of the pilar connective tissue sheath. We describe a patient with multiple perifollicular fibromas and analyze the literature on this topic. Histologically, perifollicular fibroma is characterized by a concentric arrangement of collagen fibers surroundi...

journal_title：Journal of cutaneous pathology

authors： Junkins-Hopkins JM,Cooper PH

更新日期：1994-10-01 00:00:00

abstract：:Traditionally, melanoma has been considered by surgeons to be a highly lethal malignancy, always requiring a radical surgical approach for optimal chance of cure. Yet melanoma patients who are now being referred for treatment frequently have small early lesions, and surgeons should develop a flexible attitude about ma...

journal_title：Journal of cutaneous pathology

authors： Patterson WB

更新日期：1979-06-01 00:00:00

abstract：:Formalin-fixed, paraffin-embedded biopsy specimens of 17 cases of squamous cell carcinoma of Marjolin's ulcer (SCC-MU), 6 cases of common SCC (SCC), and 5 cases of basal cell carcinoma (BCC) were stained with three monoclonal antikeratin antibodies (CAM 5.2, MAK-6, and MA-903), a monoclonal antivimentin antibody (V9),...

journal_title：Journal of cutaneous pathology

authors： Kim JM,Su WP,Kurtin PJ,Ziesmer S

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Among the pigmented lesions with a central area of scar, we found a group of cases histologically characterized by striking architectural alteration of the melanocytic component, but with no cytological atypia and mitotically quiescent. The aim of the current study was to assess the biological nature of such...

journal_title：Journal of cutaneous pathology

authors： Fabrizi G,Pennacchia I,Pagliarello C,Massi G

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the effectiveness of CD117 immunostaining for diagnosing cutaneous adnexal tumors, which has not been previously established. METHODS:CD117 immunostaining was performed on representative sections of 87 clinicopathologically confirmed cutaneous apocrine/eccrine tumors, 1...

journal_title：Journal of cutaneous pathology

authors： Goto K

更新日期：2015-07-01 00:00:00

abstract：:Cutaneous mastocytosis is a disease characterized by the infiltration and proliferation of mast cells in the skin. In children, the most common form of presentation is urticaria pigmentosa, while the diffuse cutaneous bullous mastocytosis is one of the rarest subtypes seen. The aim of this paper is to present a case o...

journal_title：Journal of cutaneous pathology

authors： Slavescu KC,Chiorean R,Danescu S,Bota M,Rogojan L,Baican A

更新日期：2016-03-01 00:00:00

abstract：:A 34-year-old man with acquired immunodeficiency syndrome presented with multiple skin lesions clinically suggestive of molluscum contagiosum. Three skin biopsy specimens were obtained which showed dermal abscesses containing multiple gram-positive cocci admixed with granular necrotic dermal material. In 2, there were...

journal_title：Journal of cutaneous pathology

authors： Boudreau S,Hines HC,Hood AF

更新日期：1988-02-01 00:00:00

abstract：:Granulomatous reactions at sites of previous cutaneous herpes zoster lesions occur, but their etiology is not known. Three tissue specimens from 5 cases identified clinically and histologically as post-zosteric granulomatous reactions were studied for the presence of varicella-zoster virus (VZV) deoxyribonucleic acid ...

journal_title：Journal of cutaneous pathology

authors： Serfling U,Penneys NS,Zhu WY,Sisto M,Leonardi C

更新日期：1993-02-01 00:00:00

abstract：:The internal organization of plasma membranes was studied in seven subjects with pemphigus vulgaris and in one subject with familial pemphigus using the freeze-fracture technique. The results obtained seem to suggest that the acantholytic process is produced in a similar fashion whatever the pathogenic agent and that ...

journal_title：Journal of cutaneous pathology

authors： Caputo R,Innocenti M,Gasparini G

更新日期：1980-04-01 00:00:00

abstract：:Sinonasal non-keratinizing squamous cell carcinoma (SCC), previously designated as transitional cell carcinoma or cylindrical cell carcinoma, is an uncommon malignant neoplasm with distinct histopathological features, considered to be a low-grade malignancy that usually occurs in elderly patients. Extensive local inva...

journal_title：Journal of cutaneous pathology

authors： Guo R,Metcalf S,Crowson AN

更新日期：2012-08-01 00:00:00

abstract：:Biologic therapies targeting tumor necrosis factor (TNF)-alpha have become a mainstay in the management of a number of autoimmune diseases. We report a series of adverse skin eruptions in six patients (four females, two males, age: 21-58 years, mean: 39) receiving 4 months to 10 years (mean 3.1 years) of anti-TNF-alph...

journal_title：Journal of cutaneous pathology

authors： Hawryluk EB,Linskey KR,Duncan LM,Nazarian RM

更新日期：2012-05-01 00:00:00

abstract：:The nuclei of spindle and epithelioid cell nevus (SECN) cells often contain inclusions. To determine the origin and pathogenesis of the nuclear inclusions, 12 cases of SECN were electron microscopically examined. True inclusions, pseudoinclusions, and electron-lucent areas were frequently found in the nuclei of SECN c...

journal_title：Journal of cutaneous pathology

authors： Sakamoto F,Ito M,Sato Y

更新日期：1990-04-01 00:00:00

abstract：:Malignant mesothelioma (MM) is an aggressive and invasive neoplasm primarily affecting the pleura, peritoneum and pericardium. While mesothelioma commonly metastasizes to visceral organs, it has rarely been documented to involve the skin and subcutaneous tissue. There is a paucity of reports of cutaneous metastatic me...

journal_title：Journal of cutaneous pathology

authors： Ward RE,Ali SA,Kuhar M

更新日期：2017-12-01 00:00:00

abstract：:Spontaneous regression (SR) of cancer is a rare but well-documented biological phenomenon, which is even rarer in the context of metastatic breast carcinoma. Different mechanisms of SR are still under debate, including immune-mediated response. We herein report a case of the SR of intralymphatic cutaneous metastases o...

journal_title：Journal of cutaneous pathology

authors： Tomasini C

更新日期：2020-08-01 00:00:00

abstract：:We report the case of a 51-year-old man with an asymptomatic indurated plaque on the chest wall that was surgically excised and submitted for histopathological examination. Microscopically, the dermis was occupied by a neoplastic process with spindle-shaped cells arranged in longitudinal fascicles with cytologic atypi...

journal_title：Journal of cutaneous pathology

authors： Berzal-Cantalejo F,Sabater-Marco V,Pérez-Vallés A,Martorell-Cebollada M

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Recent genetic investigations support the idea that basal cell carcinoma (BCC) is trichoblastic carcinoma. However, it is generally thought that clear cell basal cell carcinoma is a result of degeneration rather than tricholemmal differentiation. METHODS:We report a case of BCC, with clear cell components, ...

journal_title：Journal of cutaneous pathology

authors： Misago N,Satoh T,Narisawa Y

更新日期：2003-03-01 00:00:00

abstract：:Two patients with solitary lesions of pagetoid reticulosis are presented. A third case with disseminated lesions and similar microscopic detail is also reported. Lighg microscopic findings include an abnornal cell infiltrate confined to the epidermis and distributed diffusely in a pagetoid pattern. In ultrathin sectio...

journal_title：Journal of cutaneous pathology

authors： Wood WS,Killby VA,Stewart WD

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Fatty acid synthase (FAS), the key enzyme responsible for the synthesis of fatty acids, is weakly expressed in some normal human tissues. Recently, FAS has been demonstrated to be overexpressed in many non-neoplastic highly proliferative lesions and in aggressive carcinomas with poor outcome, including colon...

journal_title：Journal of cutaneous pathology

authors： Innocenzi D,Alò PL,Balzani A,Sebastiani V,Silipo V,La Torre G,Ricciardi G,Bosman C,Calvieri S

更新日期：2003-01-01 00:00:00

abstract：:Goltz syndrome (focal dermal hypoplasia) is an X-linked dominant disorder that is classically associated with yellowish papules representing fat herniation (superficial adipocytes). We report a series of three cases, with clinicopathologic correlation of biopsies from Blaschkoid streaks. A range of histopathologic fea...

journal_title：Journal of cutaneous pathology

authors： Ko CJ,Antaya RJ,Zubek A,Craiglow B,Damsky W,Galan A,McNiff JM

更新日期：2016-05-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA) is a well-established marker for sweat gland differentiation in adnexal neoplasms. In contrast to previous assumptions, CEA does not represent a single oncofetal antigen but comprises a family of homologous glycoproteins, i.e. the classical CEA-180, biliary glycoprotein (BGP), and non-sp...

journal_title：Journal of cutaneous pathology

authors： Metze D,Grunert F,Neumaier M,Bhardwaj R,Amann U,Wagener C,Luger TA

更新日期：1996-02-01 00:00:00

abstract：:Oral mucosal melanoma (OMM) is an extremely rare malignancy, accounting for < 0.5% of all melanomas and all oral malignancies. The rarity of OMM, the heterogeneity in clinical and histopathologic appearances, and the paucity of molecular and genetic studies to date have limited our knowledge of the etiopathogenesis of...

journal_title：Journal of cutaneous pathology

authors： Kumar SK,Shuler CF,Sedghizadeh PP,Kalmar JR

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:The Wnt-signaling pathway, involving beta-catenin, apc, and axin, plays a critical role in numerous developmental events. Alterations in the Wnt-signaling pathway have been detected in a wide variety of neoplasms. However, similar aberrations have not been described in Merkel cell carcinoma (MCC). The aim of...

journal_title：Journal of cutaneous pathology

authors： Liu S,Daa T,Kashima K,Kondoh Y,Yokoyama S

更新日期：2007-01-01 00:00:00