Chordoma involving the skin: an immunohistochemical study of 11 cases.

abstract：:Peristomal ulcer with cutaneous intestinal metaplasia, defined by scattered colonic crypts within variably intact epidermis, is an exceedingly rare pathologic diagnosis, which possesses the potential to progress to primary adenocarcinoma. Herein, we report the third case of cutaneous intestinal metaplasia in a peristo...

journal_title：Journal of cutaneous pathology

authors： Tinker DG,Roberts S,Hurley MY,Missall TA

更新日期：2020-05-01 00:00:00

abstract：:The histogenesis of atypical fibroxanthoma (AFX) and its relationship to malignant fibrous histiocytoma (MFH) are a subject of controversy. Many investigators have proposed that AFX may represent a reactive process, while others contend that it is a true fibrohistiocytic neoplasm, closely related to MFH. In an attempt...

journal_title：Journal of cutaneous pathology

authors： Worrell JT,Ansari MQ,Ansari SJ,Cockerell CJ

更新日期：1993-06-01 00:00:00

abstract：:The distribution of desmoglein, plakoglobin, E-cadherin, and beta-catenin in the peri-lesional and lesional skin of Hailey-Hailey disease, Darier's disease, and pemphigus vulgaris was examined by immunoelectron microscopy. In the peri-lesional skin, the immunolabeling of these desmosomal components was localized to de...

journal_title：Journal of cutaneous pathology

authors： Tada J,Hashimoto K

更新日期：1998-02-01 00:00:00

abstract：:We examined 32 cases (38 lesions) of extramammary Paget's disease (EMPD) in relation to comparative studies on intraductal carcinoma of the breast (ductal carcinoma in situ, DCIS) and apocrine adenocarcinoma (AAC). Lesions included scrotum (18 lesions), vulva (8), axilla (6), groin (3), penis (2) and chest wall (1), a...

journal_title：Journal of cutaneous pathology

authors： Urabe A,Matsukuma A,Shimizu N,Nishimura M,Wada H,Hori Y

更新日期：1990-10-01 00:00:00

abstract：:We report a rare case of multiple, co-exisitng verruciform xanthomas (VXs) of the anogenital region in the setting of cutaneous trauma. VX is a rare benign mucocutaneous neoplasm that typically presents as a solitary lesion with a predilection for the oral cavity, although extra-oral lesions have been reported involvi...

journal_title：Journal of cutaneous pathology

authors： Cumberland L,Dana A,Resh B,Fitzpatrick J,Goldenberg G

更新日期：2010-08-01 00:00:00

abstract：:The authors have observed 15 examples of a distinctive fibrohistiocytic lesion in children and adolescents which they chose to designate as "atypical fibrous histiocytoma" (AFH). Patient ages ranged from 1 to 19 years (mean 9.3 yr.). Only two cases were encountered in the first year of life, but 7 were seen in childre...

journal_title：Journal of cutaneous pathology

authors： Marrogi AJ,Dehner LP,Coffin CM,Wick MR

更新日期：1992-08-01 00:00:00

abstract：:A case of squamous cell carcinoma (SCC) with regional lymph node metastasis in a 69-year-old Japanese man is reported. The tumor was characterized by the proliferation of peripheral basaloid, inner squamoid, and glycogen-rich cells, the presence of trichilemmal keratinization, and the presence of ladder-like, membrane...

journal_title：Journal of cutaneous pathology

authors： Yamamoto O,Asahi M,Horie A,Fujimoto S,Nakayama K

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Podoconiosis is a familial geochemical dermatosis which is common in Ethiopia but relatively unknown in Europe/United States. It is related to exposure of bare feet to volcanic soil and presents with extensive bilateral lymphedema of legs and feet. Histopathological and immunohistochemical features of it hav...

journal_title：Journal of cutaneous pathology

authors： Wendemagegn E,Tirumalae R,Böer-Auer A

更新日期：2015-03-01 00:00:00

abstract：:We present a case of a 64-year-old man with refractory acute myeloid leukemia and trisomy 8 who developed leukemia cutis. Interphase fluorescence in situ hybridization (FISH) was performed on a paraffin-embedded skin section. FISH confirmed a population of cells with trisomy 8 in the blastic infiltrates involving the ...

journal_title：Journal of cutaneous pathology

authors： Shvartsbeyn M,Meehan SM,Gu P,Nierodzik ML,Perle MA

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Telomerase plays a role in the immortalization of cells and carcinogenesis. Previous studies have yielded conflicting results on whether human telomerase RNA (hTER) expression differs in nevi, atypical nevi and melanomas using polymerase chain reaction-based telomeric repeat amplification protocol or in situ...

journal_title：Journal of cutaneous pathology

authors： Fullen DR,Zhu W,Thomas D,Su LD

更新日期：2005-11-01 00:00:00

abstract：:To explore the clinicopathological features of a rare dedifferentiated liposarcoma (DDLPS) with meningothelial-like whorls, we retrospectively analyzed 46 reported cases and 1 case that we encountered. Fluorescence in situ hybridization (FISH) analysis of the MDM2 amplification status of our case was also performed. O...

journal_title：Journal of cutaneous pathology

authors： Chen S,He S,Huang H,Li L,Wang W,Cui Z,Zhang R

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Becker nevus (BN) is a unilateral, hairy, pigmented cutaneous hamartoma that frequently appears in adolescence. Several features of BN suggest that increased androgen sensitivity plays a role in its pathogenesis. There have been only a few studies of histopathologic and immunohistochemical characteristics of...

journal_title：Journal of cutaneous pathology

authors： Kim YJ,Han JH,Kang HY,Lee ES,Kim YC

更新日期：2008-12-01 00:00:00

abstract：:Biologic therapies targeting tumor necrosis factor (TNF)-alpha have become a mainstay in the management of a number of autoimmune diseases. We report a series of adverse skin eruptions in six patients (four females, two males, age: 21-58 years, mean: 39) receiving 4 months to 10 years (mean 3.1 years) of anti-TNF-alph...

journal_title：Journal of cutaneous pathology

authors： Hawryluk EB,Linskey KR,Duncan LM,Nazarian RM

更新日期：2012-05-01 00:00:00

abstract：:Brooke-Spiegler syndrome represents an autosomal dominant disease characterized by the occurrence of multiple cylindromas, trichoepitheliomas and (sporadically) spiroadenomas. Patients with Brooke-Spiegler syndrome are also at risk of developing tumors of the major and minor salivary glands. Patients with Brooke-Spieg...

journal_title：Journal of cutaneous pathology

authors： Ponti G,Nasti S,Losi L,Pastorino L,Pollio A,Benassi L,Giudice S,Bertazzoni G,Veratti E,Azzoni P,Bianchi Scarrà G,Seidenari S

更新日期：2012-03-01 00:00:00

abstract：:Although CD1a+ dendritic cells (DC) in cutaneous T-cell lymphomas (CTCL) have been well documented, the presence of large numbers of DC within lymphoid infiltrates can pose a diagnostic difficulty. We present a case of a 70-year-old man with a 3-year history of recurrent red papules and plaques on the extremities and ...

journal_title：Journal of cutaneous pathology

authors： Jokinen CH,Wolgamot GM,Wood BL,Olerud J,Argenyi ZB

更新日期：2007-07-01 00:00:00

abstract：:Cellular adhesion molecules are newly identified mediators of angiogenesis. Infantile hemangiomas, characterized in the early stages by a proliferation of poorly differentiated vessels followed in the late stages by a vascular differentiation and regression of the tumor, represent an interesting model to study angioge...

journal_title：Journal of cutaneous pathology

authors： Verkarre V,Patey-Mariaud de Serre N,Vazeux R,Teillac-Hamel D,Chretien-Marquet B,Le Bihan C,Leborgne M,Fraitag S,Brousse N

更新日期：1999-01-01 00:00:00

abstract：:Oral mucosal melanoma (OMM) is an extremely rare malignancy, accounting for < 0.5% of all melanomas and all oral malignancies. The rarity of OMM, the heterogeneity in clinical and histopathologic appearances, and the paucity of molecular and genetic studies to date have limited our knowledge of the etiopathogenesis of...

journal_title：Journal of cutaneous pathology

authors： Kumar SK,Shuler CF,Sedghizadeh PP,Kalmar JR

更新日期：2008-04-01 00:00:00

abstract：:Langerhans cell histocytosis (LCH) and Erdheim-Chester disease are two rare histiocytic disorders. Their occurrence in the same patient is more infrequent, but has been described. We report a case of a 38-year-old woman who presented with a diagnosis of single system cutaneous LCH. Subsequently, she developed multiple...

journal_title：Journal of cutaneous pathology

authors： Johnson WT,Patel P,Hernandez A,Grandinetti LM,Huen AC,Marks S,Ho J,Monaco SE,Jaffe R,Picarsic J

更新日期：2016-03-01 00:00:00

abstract：:A 12-year-old male presented with an 8-year history of five firm cream colored papules on the right vertex of the scalp. A biopsy showed a dense infiltrate of monomorphous mast cells involving the dermis and extending into the subcutis. A relatively well-circumscribed cluster of larger cells showed pleomorphic nuclei ...

journal_title：Journal of cutaneous pathology

authors： Lachapelle J,Moroz B,Nguyen VH

更新日期：2012-08-01 00:00:00

abstract：:We report a 20-year-old male patient with an atypical Spitz tumor, located in the dorsal aspect of his left hand, and a positive sentinel axillary lymph node. After lymphadenectomy, 1 of 23 non-sentinel lymph nodes excised was found to contain small multiple deposits of large spindle atypical melanocytes. Reviewing th...

journal_title：Journal of cutaneous pathology

authors： Urso C,Borgognoni L,Doria M,Tinacci G,Zini E

更新日期：2009-05-01 00:00:00

abstract：:Goltz syndrome (focal dermal hypoplasia) is an X-linked dominant disorder that is classically associated with yellowish papules representing fat herniation (superficial adipocytes). We report a series of three cases, with clinicopathologic correlation of biopsies from Blaschkoid streaks. A range of histopathologic fea...

journal_title：Journal of cutaneous pathology

authors： Ko CJ,Antaya RJ,Zubek A,Craiglow B,Damsky W,Galan A,McNiff JM

更新日期：2016-05-01 00:00:00

abstract：:Recently, T-cell lymphoma localized to the subcutaneous tissue has been reported. We report the clinical, histologic, immunohistochemical, and molecular genetic findings in 6 patients who we believe had this peculiar T-cell lymphoma with its unique morphologic and clinical features. All patients presented with deep-se...

journal_title：Journal of cutaneous pathology

authors： Mehregan DA,Su WP,Kurtin PJ

更新日期：1994-04-01 00:00:00

abstract：:An 11-year old Caucasian female with a remote history of urticaria pigmentosa presented with a neck mass. A biopsy demonstrated a large intradermal nodule composed of unusually large epithelioid mast cells, including a prominent subset with bi-lobed and multi-lobed nuclei. By immunohistochemistry, the cells expressed ...

journal_title：Journal of cutaneous pathology

authors： Tran DT,Jokinen CH,Argenyi ZB

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:BRAF inhibition has improved overall survival in patients with BRAF mutant melanoma, but this is associated with a range of known and predictable cutaneous side effects, including squamous cell carcinomas associated with RAS mutations. METHODS:We identified three severely dysplastic nevi, one atypical intra...

journal_title：Journal of cutaneous pathology

authors： Parekh V,Sobanko J,Miller CJ,Karakousis G,Xu W,Letrero R,Elenitsas R,Xu X,Elder DE,Amaravadi R,Schuchter LM,Nathanson KL,Wilson MA,Chu EY

更新日期：2019-03-01 00:00:00

abstract：:Eccrine nevi are rare hamartomas characterized by an increase in the number or size of eccrine glands. A polypoid form located in the coccygeal area has been described in a few cases and termed coccygeal polypoid eccrine nevus (CPEN). No association with internal malformations was reported in any of these cases. We de...

journal_title：Journal of cutaneous pathology

authors： Frouin E,Riviere B,Maillet O,Willems M,Kalfa N,Costes V,Bessis D

更新日期：2016-08-01 00:00:00

abstract：:Trichilemmoma is considered a benign neoplasm derived from the outer root sheath of the hair follicle. Although the histogenesis of the lesion is unknown, a relationship between human papillomavirus (HPV) infection and development of these tumors has been suggested on morphologic observations. In order to determine wh...

journal_title：Journal of cutaneous pathology

authors： Leonardi CL,Zhu WY,Kinsey WH,Penneys NS

更新日期：1991-06-01 00:00:00

abstract：:Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive form of peripheral T-cell lymphoma, characterized by systemic symptoms, diffuse lymphadenopathy, hepatosplenomegaly and immunodysregulation. Half of AITL is associated with cutaneous symptoms, but only few cases with bullous eruption have been described. Assoc...

journal_title：Journal of cutaneous pathology

authors： Colmant C,Camboni A,Dekeuleneer V,Marot L,Dachelet C,Baeck M

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Chronic urticaria is a condition with many inciting factors and often presents a therapeutic challenge to clinicians. In addition to a central role for mast cells, an immune dysregulated state related to cytokine/chemokine alterations is increasingly being recognized. METHODS:Biopsies of chronic urticaria (...

journal_title：Journal of cutaneous pathology

authors： Moy AP,Murali M,Nazarian RM

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Latent infection by human papillomavirus (HPV) has been described for genital (mucosal) and epidermodysplasia verruciformis subtypes. Only rarely has cutaneotropic, non-oncogenic HPV been found by polymerase chain reaction studies in normal skin. METHODS:We noted myrmecia wart inclusions as an incidental hi...

journal_title：Journal of cutaneous pathology

authors： Wititsuwannakul J,Ko CJ

更新日期：2012-10-01 00:00:00

abstract：:The advent of immunoperoxidase technique on paraffin embedded tissue has identified a number of shared immunologic markers present in various lymphoproliferative cutaneous disorders. Two such disorders are the recently described primary cutaneous CD30-positive anaplastic large cell lymphoma (ALCL) and lymphomatoid pap...

journal_title：Journal of cutaneous pathology

authors： Tomaszewski MM,Lupton GP,Krishnan J,May DL

更新日期：1995-08-01 00:00:00