Extramammary Paget's disease: comparative histopathologic studies of intraductal carcinoma of the breast and apocrine adenocarcinoma.

abstract：:The histogenetic relationship amongst various dendritic cells of the dermis which may express markers including factor XIIIa (FXIIIa) or CD34 remains unclear. In this study we utilized a sensitive indirect immunoperoxidase staining technique to identify CD34 and FXIIIa, as well the monocyte/macrophage markers KP-1 and...

journal_title：Journal of cutaneous pathology

authors： Altman DA,Nickoloff BJ,Fivenson DP

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Chromoblastomycosis is a chronic, suppurative, granulomatous mycosis usually confined to skin and subcutaneous tissues. The host defense mechanisms in chromoblastomycosis have not been extensively investigated. The purpose of the present study was to determine the distribution and pathways of the fungal anti...

journal_title：Journal of cutaneous pathology

authors： Sotto MN,De Brito T,Silva AM,Vidal M,Castro LG

更新日期：2004-01-01 00:00:00

abstract：:Three selected cases of transient acantholytic dermatosis were studied because of their definitive correlation with sweating due to fever and/ or bed-ridden situations. Biopsy specimens were serially sectioned and acantholysis was found in the acrosyringium or traced to connect to the acrosyringium in all biopsy speci...

journal_title：Journal of cutaneous pathology

authors： Hashimoto K,Moiin A,Chang MW,Tada J

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Molluscum contagiosum (MC) is a Molluscipox virus infection of keratinocytes with hyperplasia and intracytoplasmic inclusions - the molluscum bodies (MBs). Few papers address cytokeratins (K) profile in MC, mainly focusing terminal keratinization process. METHODS:Forty-one MC lesions were subjected to immun...

journal_title：Journal of cutaneous pathology

authors： Callegaro CF,Sotto MN

更新日期：2009-12-01 00:00:00

abstract：:Sinonasal non-keratinizing squamous cell carcinoma (SCC), previously designated as transitional cell carcinoma or cylindrical cell carcinoma, is an uncommon malignant neoplasm with distinct histopathological features, considered to be a low-grade malignancy that usually occurs in elderly patients. Extensive local inva...

journal_title：Journal of cutaneous pathology

authors： Guo R,Metcalf S,Crowson AN

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Fibrofolliculomas and trichodiscomas are benign dermal neoplasms that likely derive from the mantle of the hair follicle and can occur sporadically or in association with Birt-Hogg-Dube syndrome (BHDS). Little is known about the pathogenesis and immunophenotypic properties of these entities. METHODS:We inve...

journal_title：Journal of cutaneous pathology

authors： Collins GL,Somach S,Morgan MB

更新日期：2002-10-01 00:00:00

abstract：:Primary cutaneous extranodal marginal zone lymphoma (MZL) of mucosa-associated lymphoid tissue (MALT) represents a monoclonal B-cell neoplasm that typically presents with papules, plaques or nodules. We describe a patient with a primary cutaneous MALT lymphoma with unusual clinical features and an unusual immunophenot...

journal_title：Journal of cutaneous pathology

authors： Edinger JT,Lorenzo CR,Breneman DL,Swerdlow SH

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Rare cases of a non-bullous neutrophilic dermatosis occurring in patients with lupus erythematosus (LE) have been reported, often as the presenting manifestation of the disease. METHODS:We reviewed hematoxylin and eosin-stained slides and obtained clinical information from four additional patients, two of w...

journal_title：Journal of cutaneous pathology

authors： Gleason BC,Zembowicz A,Granter SR

更新日期：2006-11-01 00:00:00

abstract：:After intradermal testing with goldsodiumthiomalate (GSTM), 5 out of 8 patients developed skin papules at the test sites, which persisted up to 20 months. The lesions were surgically excised. Histology revealed pseudolymphoma of B and T cell type containing follicular structures and occasional small granulomas. The am...

journal_title：Journal of cutaneous pathology

authors： Kalimo K,Räsänen L,Aho H,Mäki J,Mustikkamki UP,Rantala I

更新日期：1996-08-01 00:00:00

abstract：:The authors report the occurrence of lichenoid and/or subacute lupus erythematosus-like eruptions in a group of patients receiving agents with antihistaminic properties. In 1 of the patients the eruption clinically resembled lichen planus, while in 5 patients the eruption resembled subacute cutaneous lupus erythematos...

journal_title：Journal of cutaneous pathology

authors： Crowson AN,Magro CM

更新日期：1999-02-01 00:00:00

abstract：:Sarcoidosis is a granulomatous condition with diverse clinical presentations, including neurological findings. It was previously hypothesized that perineural sarcoidal granulomas in the skin may be an explanation of small-fiber neuropathy. Herein, we present a case of a 55 year old female with anesthetic cutaneous les...

journal_title：Journal of cutaneous pathology

authors： Kazi R,Kazlouskaya V,Ho J,Karunamurthy A

更新日期：2020-07-01 00:00:00

abstract：:A 59-year-old female with a cystic fibroepithelioma of Pinkus is presented. The clinical and histopathological features of this unusual variant of basal cell carcinoma are discussed. ...

journal_title：Journal of cutaneous pathology

authors： Jones CC,Ansari SJ,Tschen JA

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:The lack of highly specific clinical and histopathological criteria has contributed to the delay in diagnosis of subungual melanoma in situ in its early stages. METHODS:Eighteen cases of subungual melanoma in situ, the largest series reported to date, were analyzed to characterize the clinical and histopath...

journal_title：Journal of cutaneous pathology

authors： Park SW,Jang KT,Lee JH,Park JH,Kwon GY,Mun GH,Lee DY,Lee JB,Park KK

更新日期：2016-01-01 00:00:00

abstract：:Proliferation of the eccrine sweat duct epithelium has been associated with skin tumors, especially keratoacanthomas and basal cell carcinomas. We report our observations on the extensive sweat gland changes in a patient who had idiopathic follicular mucinosis. ...

journal_title：Journal of cutaneous pathology

authors： Berger TG,Goette DK

更新日期：1987-06-01 00:00:00

abstract：:Oral melanoacanthoma is a rarely-reported, benign pigmented lesion of oral mucosa. Spongiosis was only recently mentioned as a light-microscopical finding occasionally seen in oral melanoacanthoma, and the formation of spongiotic intraepithelial vesicles to our knowledge has never been reported. The authors discuss a ...

journal_title：Journal of cutaneous pathology

authors： Zemtsov A,Bergfeld WF

更新日期：1989-12-01 00:00:00

abstract：:The lesions of nine patients with early striae distensae (SD) during puberty were examined by light and electron microscopy. Specific changes were seen in very early stage SD, and in clinically uninvolved skin 0.5 to 3 cm remote from the edge of the long axis of the SD lesions. Sequential changes of elastolysis accomp...

journal_title：Journal of cutaneous pathology

authors： Sheu HM,Yu HS,Chang CH

更新日期：1991-12-01 00:00:00

abstract：:A 12-year-old male presented with an 8-year history of five firm cream colored papules on the right vertex of the scalp. A biopsy showed a dense infiltrate of monomorphous mast cells involving the dermis and extending into the subcutis. A relatively well-circumscribed cluster of larger cells showed pleomorphic nuclei ...

journal_title：Journal of cutaneous pathology

authors： Lachapelle J,Moroz B,Nguyen VH

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The GATA family of transcription factors is an essential regulator of cellular proliferation and differentiation. In the skin, GATA-3 is critical for epidermal stratification and maintenance of barrier function. A role for GATA-3 in the development of human cutaneous squamous cell carcinoma (SCC) is not know...

journal_title：Journal of cutaneous pathology

authors： Solus JF,Hassan K,Lee SJ,Hsi AC,Rosman IS,Dehmeri S,Schaffer A

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Pigmentation is a characteristic clinical feature of basal cell carcinomas (BCCs) in Japanese patients. The pathogenesis of melanin pigment in pigmented BCCs is poorly understood. METHODS:We have combined the techniques of morphometric analysis and electron microscopy to assess accurately the morphologic as...

journal_title：Journal of cutaneous pathology

authors： Lao LM,Kumakiri M,Kiyohara T,Kuwahara H,Ueda K

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:BRAF inhibition has improved overall survival in patients with BRAF mutant melanoma, but this is associated with a range of known and predictable cutaneous side effects, including squamous cell carcinomas associated with RAS mutations. METHODS:We identified three severely dysplastic nevi, one atypical intra...

journal_title：Journal of cutaneous pathology

authors： Parekh V,Sobanko J,Miller CJ,Karakousis G,Xu W,Letrero R,Elenitsas R,Xu X,Elder DE,Amaravadi R,Schuchter LM,Nathanson KL,Wilson MA,Chu EY

更新日期：2019-03-01 00:00:00

abstract：:Exposure to silver-containing compounds can result in reversible discoloration of the skin, presenting as an irregular brown or black macule, which can have a clinical appearance similar to melanoma. Both the clinical scenario and the histopathology are unique. Silver nitrate darkens with exposure to light, and the ar...

journal_title：Journal of cutaneous pathology

authors： Ondrasik RM,Jordan P,Sriharan A

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Cutaneous tumor metastasis may be the first manifestation of cancer, but more often is a harbinger of advanced disease that portends an ominous prognosis. All skin accessions over the past 10 years from a large Veterans Administration (VA) hospital were reviewed. METHODS:Archived histories, glass slides, an...

journal_title：Journal of cutaneous pathology

authors： Saeed S,Keehn CA,Morgan MB

更新日期：2004-07-01 00:00:00

abstract：:Extramedullary hematopoiesis (EMH) in adults is a rare event, usually associated with myeloid disorders, and can be the first sign of chronic myelomonocytic leukemia. We report a case of EMH presenting as a hemorrhagic panniculitis in a patient who did not apparently present any myeloid disorders. The patient received...

journal_title：Journal of cutaneous pathology

authors： Gallo G,Bigliardi S,Cesinaro AM

更新日期：2019-10-01 00:00:00

abstract：:Nivolumab is a programmed cell death receptor-1 (PD-1) antibody used in the treatment of metastatic or unresectable melanoma. Cutaneous reactions are the most common adverse events reported with these agents and are rarely severe or life-threatening. Here we present a case report describing the clinicopathological fin...

journal_title：Journal of cutaneous pathology

authors： Vivar KL,Deschaine M,Messina J,Divine JM,Rabionet A,Patel N,Harrington MA,Seminario-Vidal L

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Src-family tyrosine kinases (SFKs) are important regulators of keratinocyte growth and differentiation. In a broad range of cell types, persistent activation of SFKs correlates with increased cell proliferation. In this study, we determined if SFK activity is increased in cutaneous neoplasia and psoriasis, c...

journal_title：Journal of cutaneous pathology

authors： Ayli EE,Li W,Brown TT,Witkiewicz A,Elenitsas R,Seykora JT

更新日期：2008-03-01 00:00:00

abstract：:Dirofilaria repens (formerly Dirofilaria conjunctiva) is a natural parasite of the subcutaneous tissues of dogs, cats and wild carnivores in Europe, Africa and Asia. Microfilariae are transmitted to humans by various species of mosquito. An autochthonous case of subcutaneous dirofilariasis is reported in a Greek patie...

journal_title：Journal of cutaneous pathology

authors： Tzanetou K,Gasteratos S,Pantazopoulou A,Gogou C,Konidaris D,Fragia K

更新日期：2009-08-01 00:00:00

abstract：:A histologically unique condition of the sweat duct was found in a miliaria-like papular eruption on the extensor surfaces of extremities of a 41-year-old female patient. The hypertrophic epithelium of the sweat duct wall consisted of extensively vacuolated clear cells. There was mild hyperkeratosis around the sweat d...

journal_title：Journal of cutaneous pathology

authors： Izaki S,Kono E,Hirai A,Kitamura K

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:The histopathologic features of tinea vary widely and its diagnosis could be easily missed if the index of suspicion is not high. We aimed in this study to detect histopathologic features that could be a clue for diagnosis METHODS:We retrospectively reviewed 103 cases of tinea, confirmed by Periodic acid-Sc...

journal_title：Journal of cutaneous pathology

authors： Elbendary A,Valdebran M,Gad A,Elston DM

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Among the pigmented lesions with a central area of scar, we found a group of cases histologically characterized by striking architectural alteration of the melanocytic component, but with no cytological atypia and mitotically quiescent. The aim of the current study was to assess the biological nature of such...

journal_title：Journal of cutaneous pathology

authors： Fabrizi G,Pennacchia I,Pagliarello C,Massi G

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Nickel can induce cellular and nuclear damages responsible for chronic diseases, like allergic contact dermatitis (ACD). We previously showed that matrix metalloproteinase-2 (MMP-2) gene expression was induced by nickel in nontumorigenic human keratinocytes cell line (HaCat). OBJECTIVE:To investigate the si...

journal_title：Journal of cutaneous pathology

authors： Perfetto B,Lamberti M,Giuliano MT,Canozo N,Cammarota M,Baroni A

更新日期：2007-06-01 00:00:00