Indoprofen, a new non-steroidal anti-inflammatory drug, in the treatment of osteoarthrosis: report on a multi-centre study in 1629 patients.

abstract：OBJECTIVE:Based on the clear neuroanatomical delineation of many neuropathic pain (NP) symptoms, a simple tool for performing a short structured clinical encounter based on the IASP diagnostic criteria was developed to identify NP. This study evaluated its accuracy and usefulness. METHODS:A case-control study was perf...

journal_title：Current medical research and opinion

authors： Mayoral V,Pérez-Hernández C,Muro I,Leal A,Villoria J,Esquivias A

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To explore the clinical effect and radial remodeling of transradial slender 7 Fr sheath for left main bifurcation disease (LM bifurcation). METHODS:From January 2018 to September 2019, 236 patients with LM bifurcation undergoing transradial percutaneous coronary intervention (PCI) from two heart centers were...

journal_title：Current medical research and opinion

authors： Xu Y,Li Y,Shen H,Zhang B,Zhao Q,Cheng Y,Zhao Z,Guo Q,Yang J,Zhou Y

更新日期：2020-10-01 00:00:00

abstract：:This commentary critically evaluates the limitations of genetic risk predictions in multifactorial disease, with specific reference to age-related macular degeneration (AMD). AMD is a common blinding disease with 33 million people worldwide experiencing vision impairment. Although gene polymorphism combinations infer ...

journal_title：Current medical research and opinion

authors： Feigl B,Morris CP

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:The stratum corneum (SC) pharmacokinetics of terbinafine following single-dose administration of a novel cutaneous solution (film-forming solution, FFS) containing terbinafine hydrochloride and a film-forming agent, was investigated in three studies. Terbinafine 1% cream (Lamisil) was included as a benchmark ...

journal_title：Current medical research and opinion

authors： Kienzler JL,Queille-Roussel C,Mugglestone C,Ortonne JP,Larnier C

更新日期：2007-06-01 00:00:00

abstract：:A metabolic study was carried out in 6 patients requiring enteral feeding to investigate the effectiveness and tolerance of 'Nutrauxil', a ready-made liquid nutritional preparation, over a period of 8 days. The results of anthropometric and laboratory measurements, made initially and at the end of two 4-day periods, s...

journal_title：Current medical research and opinion

authors： Lee HA,Talbot S,Patil R,Jackson JM,Holland D

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:The rising prevalence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) and the recent emergence of community-associated MRSA are major clinical, public health, and economic challenges. MRSA is a leading cause of nosocomial pneumonia and complicated skin and soft-tissue infections (cSSTI). Van...

journal_title：Current medical research and opinion

authors： Stein GE,Wells EM

更新日期：2010-03-01 00:00:00

abstract：:Objective: The aim of this study was to provide recommendations for improving the design of subsequent studies through analysis of the registered coronavirus disease 2019 (COVID-19) clinical trials.Methods: A retrospective analysis of 189 trial retrievals achieved on 20 February 2020.Results: A total of 189 trials are...

journal_title：Current medical research and opinion

authors： Wang B,Lai J,Yan X,Jin F,Yao C

更新日期：2020-07-01 00:00:00

abstract：:A double-blind trial of methocarbamol versus placebo was carried out in 59 matched pairs of patients suffering from painful muscle spasm. Methocarbamol (1500 mg. q.d.s.) was found to be effective in approximately 60% of patients compared with 30% of patients receiving placebo (p less than 0.01). Side-effects were of a...

journal_title：Current medical research and opinion

authors： Valtonen EJ

更新日期：1975-01-01 00:00:00

abstract：:A clinical study was carried out to evaluate the usefulness of intravenous lorazepam, given for sedation instead of opiate narcotics or diazepam, in 25 seriously-ill patients being treated in a respiratory and intensive care unit. All but 3 patients were on assisted ventilation. Standard doses of 4 mg lorazepam were g...

journal_title：Current medical research and opinion

authors： Dundee JW,Johnston HM,Gray RC

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVE:In the four SMILE (Survival of Myocardial Infarction Long-Term Evaluation) studies, early administration of zofenopril in acute myocardial infarction (AMI) showed beneficial effects as compared to placebo and other angiotensin converting enzyme inhibitors (ACEIs). This study investigated whether the concomita...

journal_title：Current medical research and opinion

authors： Borghi C,Omboni S,Reggiardo G,Bacchelli S,Degli Esposti D,Ambrosioni E,SMILE (Survival of Myocardial Infarction Long-Term Evaluation) Working Project.

更新日期：2018-10-01 00:00:00

abstract：MOTIVATION:The American Society of Parenteral and Enteral Nutrition (ASPEN) guidelines advise use of enteral nutrition (EN) for critically ill hospital patients requiring nutritional support, but no studies have comprehensively estimated economic benefits from adherence to this recommendation. METHODS:We systematicall...

journal_title：Current medical research and opinion

authors： Cangelosi MJ,Auerbach HR,Cohen JT

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:High-sensitivity C-reactive protein (hs-CRP) has been explored for use in predicting cardiovascular risk. The recent Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) study found that statin therapy reduced cardiovascular events in those with ...

journal_title：Current medical research and opinion

authors： Slejko JF,Page RL 2nd,Sullivan PW

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To investigate whether gum chewing affects perceived levels of everyday stress among persons who (1) regularly chew gum or (2) do not chew gum on a regular basis. RESEARCH DESIGN AND METHODS:Two Internet-based studies were conducted. Study 1 enrolled participants who chewed gum > or =4 days per week, chewed ...

journal_title：Current medical research and opinion

authors： Zibell S,Madansky E

更新日期：2009-06-01 00:00:00

abstract：:The effects of flurbiprofen on various coagulation and haemostasis parameters were studied in 19 patients adequately anticoagulated on a fixed dose of phenprocoumon. Laboratory controls were performed 5 times at weekly intervals. Flurbiprofen 50 mg 3-times daily was given for 2 weeks after an initial control period of...

journal_title：Current medical research and opinion

authors： Marbet GA,Duckert F,Walter M,Six P,Airenne H

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:Most registration studies for new osteoporosis drugs have used a combination of quantitative morphometry (QM) and visual semiquantitative reading (SQ) to define vertebral fractures. However, in the pivotal teriparatide Fracture Prevention Trial (ClinicalTrials.gov Identifier: NCT00670501), vertebral fractures...

journal_title：Current medical research and opinion

authors： Prevrhal S,Krege JH,Chen P,Genant H,Black DM

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Despite a plethora of published data on levocetirizine, no meta-analyses exist on the effect of study design, and covariates like age, gender, and baseline symptom severity on treatment response. The objective of this study was the efficacy of levocetirizine 5  mg tablets and matching placebo at reducing alle...

journal_title：Current medical research and opinion

authors： Boev R,Song D,Bedenbaugh A,Haeusler JM

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:There is growing evidence describing DNA repair genes polymorphisms are related to increased cancer risk including colorectal cancer (CRC). The aim of this study was to investigate the associations between the APE1 Asp148Glu, hOGG1 Ser326Cys, XRCC1 Arg399Gln, XRCC3 Thr241Met, XPD Lys751Gln, XPG Asp1104His po...

journal_title：Current medical research and opinion

authors： Canbay E,Cakmakoglu B,Zeybek U,Sozen S,Cacina C,Gulluoglu M,Balik E,Bulut T,Yamaner S,Bugra D

更新日期：2011-07-01 00:00:00

abstract：:Objectives: The purpose of this study was to assess (1) the trends of and (2) the factors associated with health information technology (HIT) use among older adults in the U.S.Methods: A decade (2009-2018) of data from the U.S. National Health Interview Survey (NHIS) was used. The trends of HIT use among older adults ...

journal_title：Current medical research and opinion

authors： Hung LY,Lyons JG,Wu CH

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:Healthcare providers managing older patients with type 2 diabetes mellitus (T2DM) face a complex milieu of medical conditions and comorbidities, which increase the risk of unintended treatment consequences. The objective of this study was to understand factors associated with hypoglycemia-related hospitalizat...

journal_title：Current medical research and opinion

authors： Fu H,Xie W,Curtis B,Schuster D

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:Luseogliflozin is a novel sodium glucose cotransporter 2 inhibitor for type 2 diabetes mellitus (T2DM) treatment. An exploratory Phase II study was conducted to assess the efficacy and safety of several doses of luseogliflozin in Japanese T2DM patients. PATIENTS AND METHODS:Japanese T2DM patients aged 20-74 ...

journal_title：Current medical research and opinion

authors： Seino Y,Sasaki T,Fukatsu A,Sakai S,Samukawa Y

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To examine outcomes associated with colesevelam treatment among patients with hypercholesterolemia in real-world clinical practice. METHODS:This analysis was conducted as a retrospective, observational cohort study in an ambulatory-care medical network in Northern California. Patients with orders for colesev...

journal_title：Current medical research and opinion

authors： Romanelli RJ,Leahy A,Jukes T,Ye X,Qian C,Ishisaka DY

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:Recent survey data have reported the incidence rate of needlestick injuries (NIs) and NIs which draw blood sustained by nurses caring for patients with diabetes in an in-patient hospital setting. The purpose of this study was to deduce the potential short-term annual economic impact resulting from such NI, and ...

journal_title：Current medical research and opinion

authors： Lee WC,Nicklasson L,Cobden D,Chen E,Conway D,Pashos CL

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea syndrome (OSAS) is mostly seen in adult populations. It is known that increased levels of several inflammatory mediators play roles in OSAS and related comorbidities. Calprotectin is an inflammatory mediator that increases in some diseases such as Behçet's syndrome, bowel diseases and...

journal_title：Current medical research and opinion

authors： Torun MT,Ünver E,Yalçın Y,Kanmaz L,Seçkin E

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Inadequate treatment by non-specialty primary care physicians (PCPs) has been a concern in improving osteoporosis care. An increase in outpatient visits by older patients seeking osteoporosis care has been reported. But what percentages of these visits are made to PCPs are unknown. We investigated recent tre...

journal_title：Current medical research and opinion

authors： Rianon N,Anand D,Rasu R

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:In TRITON-TIMI 38, patients with acute coronary syndromes were treated with prasugrel or clopidogrel, with aspirin, for a median of 14.5 (maximum of 15) months. Based on this trial, the EU label for prasugrel recommends treatment for up to 12 months and excludes patients with prior stroke/transient ischemic ...

journal_title：Current medical research and opinion

authors： Wilcox R,Iqbal K,Costigan T,Lopez-Sendon J,Ramos Y,Widimsky P

更新日期：2014-11-01 00:00:00

abstract：:A trial was carried out in 30 patients to assess the effectiveness of indanyl carbenicillin in acute or chronic urinary tract infections, many of which were complicated by a pathological urological or medical condition. In all patients, infection was due to a single species of pathogen: E. coli (19), Proteus (6), and ...

journal_title：Current medical research and opinion

authors： Giamarellou E,Papazachos G,Piperakis G,Daikos G

更新日期：1976-01-01 00:00:00

abstract：:In a multi-centre study, the antidepressant efficacy and incidence of on-therapy events of trazodone (100 to 400 mg daily) and mianserin (30 to 120 mg daily) was compared using a double-blind pre-determined randomized parallel group design in depressed patients unresponsive to placebo after a 7-day screening period. O...

journal_title：Current medical research and opinion

authors： Bennie EH,Khan MC,Tyrer SP,Siddiqui U,Ankier SI

更新日期：1984-01-01 00:00:00

abstract：:Drs Godman and Fadare review the paper by Mares-Garcia and colleagues in Spain regarding the extent of non-guideline recommended prescribing (NGRP) of proton pump inhibitors (PPIs) in ambulatory care. NGRP of PPIs is an increasing public health concern given the implications of overuse of PPIs on infection rates, oste...

journal_title：Current medical research and opinion

authors： Godman B,Fadare J

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Patients with type 2 diabetes (T2DM) often have multiple comorbidities which may impact the selection of antihyperglycemic therapies. The purpose of this study was to quantify the prevalence and co-prevalence of common comorbidities. RESEARCH DESIGN AND METHODS:A retrospective study was conducted using the Q...

journal_title：Current medical research and opinion

authors： Iglay K,Hannachi H,Joseph Howie P,Xu J,Li X,Engel SS,Moore LM,Rajpathak S

更新日期：2016-07-01 00:00:00

abstract：:A long-term follow-up study was carried out in 44 Type II diabetic patients to confirm the lack of effect of gliclazide on body weight as well as its hypoglycaemic efficacy and tolerance. Patients were assessed for up to 51 months. The results showed no overall significant change in body weight, 21 patients gaining we...

journal_title：Current medical research and opinion

authors： Robb GH,Lowe SM

更新日期：1984-01-01 00:00:00