Interaction study between phenprocoumon and flurbiprofen.

abstract：OBJECTIVE:The objectives of this survey were to understand (1) the effects of overactive bladder (OAB) and urinary incontinence (UI) on women's lives and to understand (2) women's needs and expectations of health care providers and treatment related to these disorders. METHODS:Women (N = 1046) with self-reported sympt...

journal_title：Current medical research and opinion

authors： MacDiarmid S,Rosenberg M

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:With a growing number of studies and comparators in MRSA skin infections, a unified framework for comparing treatments is needed for health technology assessment (HTA). The objective was to systematically assess the success rates of common antimicrobial agents for the treatment of complicated skin and soft ti...

journal_title：Current medical research and opinion

authors： Logman JF,Stephens J,Heeg B,Haider S,Cappelleri J,Nathwani D,Tice A,van Hout BA

更新日期：2010-07-01 00:00:00

abstract：:Atypical antipsychotics are commonly used off-label to treat behavioural and psychiatric symptoms in dementia (BPSD), particularly in elderly care homes. Much of this use is inappropriate, and trials have shown an increased likelihood of serious cerebrovascular adverse events (CVAEs) such as stroke and transient ische...

journal_title：Current medical research and opinion

authors： Bullock R

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To assess whether maintenance of labor epidural analgesia using programmed intermittent epidural bolus (PIEB) is associated with reduced local anesthetic (LA) consumption, patient-controlled epidural analgesia (PCEA) use, and rescue analgesia requirements compared to continuous epidural infusion (CEI). RESEA...

journal_title：Current medical research and opinion

authors： Tien M,Allen TK,Mauritz A,Habib AS

更新日期：2016-08-01 00:00:00

abstract：INTRODUCTION:Tumor hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) expression are important factors influencing treatment response and selection in patients with metastatic breast cancer (mBC). Using the LifeLink Oncology Analyzer Database, we classified mBC patients by combined HR and HER2 st...

journal_title：Current medical research and opinion

authors： Gao S,Barber B,Schabert V,Ferrufino C

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Transient ischemic attack (TIA) is a serious condition which should be considered on the same spectrum as other conditions involving brain ischemia. Efficient management of these patients is therefore critical. The aim of this research was to gain insights into 'real-world' global trends of the current manage...

journal_title：Current medical research and opinion

authors： Jäkel A,Plested M,Chapman AM,Jackson D,Purroy F

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To compare the effectiveness of antiresorptive agents in reducing the risk of vertebral and non-vertebral fractures using data from published meta-analyses and the technique of adjusted indirect comparisons. RESEARCH DESIGN AND METHODS:Pairs of agents were compared by adjusted indirect comparison of 0.56 [0....

journal_title：Current medical research and opinion

authors： Wehren LE,Hosking D,Hochberg MC

更新日期：2004-04-01 00:00:00

abstract：:In this narrative review, we will discuss some of the significant risks and dramatic consequences that are associated with epilepsy: depression, suicide, seizure-related injuries, and mortality, both in adults and in children. Considering the high prevalence of depression among people with epilepsy (PWE), routine and ...

journal_title：Current medical research and opinion

authors： Mesraoua B,Deleu D,Hassan AH,Gayane M,Lubna A,Ali MA,Tomson T,Khalil BA,Cross JH,Asadi-Pooya AA

更新日期：2020-09-01 00:00:00

abstract：:Neuroprotective agents inhibit reactions in the brain ischaemic injury cascade which lead to neuronal death. Gamma-aminobutyric acid (GABA) is a naturally occurring inhibitory neurotransmitter that increases chloride influx into the neuron and counteracts the toxic effects of glutamate. Clomethiazole is a GABA(A) agon...

journal_title：Current medical research and opinion

authors： Vaishnav A,Lutsep HL

更新日期：2002-01-01 00:00:00

abstract：INTRODUCTION:Azelastine hydrochloride (Astelin) nasal spray 0.1% solution is a second-generation intranasal antihistamine available in the US for treatment of both seasonal allergic rhinitis (SAR) and nonallergic vasomotor rhinitis (VMR). SCOPE:Searches of journal articles including the title word 'azelastine' from 19...

journal_title：Current medical research and opinion

authors： Bernstein JA

更新日期：2007-10-01 00:00:00

abstract：:An open clinical evaluation was carried out in 736 African out-patients suffering from rheumatic and inflammatory disorders to assess the efficacy and tolerability of tenoxicam in relieving the signs and symptoms of their condition. On entry, all previous treatment was discontinued and patients received a simple daily...

journal_title：Current medical research and opinion

authors： Ibrahima K,Kodjo G,Issa S,Seye L,Cisse F,Eassey G,Rietiker S

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Eribulin mesylate (eribulin) is indicated for patients with metastatic breast cancer (MBC) who have previously received at least two chemotherapies in the US and for patients with locally advanced breast cancer (LABC) or MBC who have progressed after at least one chemotherapy in the European Union (EU). In b...

journal_title：Current medical research and opinion

authors： Chabot I,Zhao Q,Su Y

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis (AR) can have substantial negative impact on children. Most notably, it can impede learning during the school-age years. Other consequences include adverse behavioral and psychosocial effects, poor quality of life, and potential impact on serious comorbidities, such as asthma. CONSENSUS PA...

journal_title：Current medical research and opinion

authors： Blaiss MS,Allergic Rhinitis in Schoolchildren Consensus Group.

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Estimate the proportion of phosphodiesterase type-5 inhibitor (PDE5-I) patients who co-possess nitrates and compare the proportion of tadalafil patients dispensed nitrates to a matched control group. Secondarily, examine the percentage of co-possession of PDE5-Is and nitrates where the products were dispensed...

journal_title：Current medical research and opinion

authors： Chang LL,Ma M,Allmen Hv,Henderson SC,Harper K,Hornbuckle K

更新日期：2010-06-01 00:00:00

abstract：:A total of 247 patients suffering from rheumatoid arthritis and allied conditions were referred for routine ophthalmological examination with particular reference to ocular rheumatoid involvement. Of these, 197 were already receiving ibuprofen before their first assessment while 50 had a baseline assessment before com...

journal_title：Current medical research and opinion

authors： Williamson J,Sturrock RD

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and long-term safety of linagliptin added to basal insulin in Asian patients with type 2 diabetes mellitus (T2DM) inadequately controlled by basal insulin with/without oral agents. RESEARCH DESIGN AND METHODS:This was a post hoc analysis of Asian patients from a global ≥52 week study...

journal_title：Current medical research and opinion

authors： Sheu WH,Park SW,Gong Y,Pinnetti S,Bhattacharya S,Patel S,Seck T,Woerle HJ

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To compare clinical characteristics, statin treatment patterns and adherence among patients at different risk for coronary heart disease (CHD) as defined by National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III guidelines. METHODS:Patients ≥ 18 years old with ≥ 1 claim for dyslipidemi...

journal_title：Current medical research and opinion

authors： Kern DM,Balu S,Tunceli O,Anzalone D

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:A recent retrospective meta-analysis of cardiovascular events from long-term studies with acarbose in type 2 diabetes showed that treatment was associated with a significant reduction in the risk of cardiovascular events, supporting the hypothesis that postprandial hyperglycemia is a risk factor for cardiovas...

journal_title：Current medical research and opinion

authors： Roze S,Valentine WJ,Evers T,Palmer AJ

更新日期：2006-07-01 00:00:00

abstract：:In a randomized trial, 149 patients with uncomplicated gonorrhoea were treated with a single intramuscular dose of 1.0 g mezlocillin, 150 with 2.0 g ampicillin plus 1.0 g probenecid orally and 150 with a single dose of 1.8 mega units of procaine penicillin. Cure rates at 3, 10 and 17 days after treatment were 97%, 99%...

journal_title：Current medical research and opinion

authors： Khan MH,Tomkyns JG

更新日期：1982-01-01 00:00:00

abstract：:A clinical evaluation was carried out in 19 patients with lichen ruber planus to assess the effectiveness of 0.05% betamethasone-17,21-dipropionate ointment in the treatment of patients whose lesions had developed resistance to prolonged treatment with 0.1% betamethasone-17-valerate ointment. The new steroid ointment ...

journal_title：Current medical research and opinion

authors： Björnberg A,Hellgren L

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of rosuvastatin in postmenopausal women with hypercholesterolemia who are receiving hormone replacement therapy (HRT) in a randomized, double-blind, placebo-controlled trial. METHODS:After a 6-week dietary lead-in period, 135 postmenopausal women who had been taking a stab...

journal_title：Current medical research and opinion

authors： Shepherd J,Packard C,Littlejohn TW 3rd,Walker J,Stein EA,Smith K,Kallend D,Blasetto JW

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:Hyperuricaemia is associated with indapamide administration. In contrast, micronised fenofibrate can significantly decrease serum uric acid levels. However, there are no data on the effect of combination therapy of indapamide with micronised fenofibrate on uric acid metabolism. METHODS:We studied 20 non-diab...

journal_title：Current medical research and opinion

authors： Achimastos A,Liberopoulos E,Nikas S,Bairaktari E,Miltiadous G,Tsimihodimos V,Elisaf M

更新日期：2002-01-01 00:00:00

abstract：:A trial was carried out in 30 patients to assess the effectiveness of indanyl carbenicillin in acute or chronic urinary tract infections, many of which were complicated by a pathological urological or medical condition. In all patients, infection was due to a single species of pathogen: E. coli (19), Proteus (6), and ...

journal_title：Current medical research and opinion

authors： Giamarellou E,Papazachos G,Piperakis G,Daikos G

更新日期：1976-01-01 00:00:00

abstract：:In a single-blind study in general practice, 60 patients with anxiety neuroses were randomly allocated to receive either 0.5 mg haloperidol twice daily or 2 mg diazepam 3-times daily for 6 weeks. Eighteen patients (6 on haloperidol and 12 on diazepam) were excluded from the analysis of efficacy. On the Hamilton Rating...

journal_title：Current medical research and opinion

authors： Budden MG

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:Aliskiren is the first in a new class of orally effective direct renin inhibitors approved for the treatment of hypertension. This multiple-dose study investigated the potential for pharmacokinetic interactions between aliskiren and three drugs, each predominantly eliminated by a different clearance/metabolic...

journal_title：Current medical research and opinion

authors： Ayalasomayajula S,Tchaloyan S,Yeh CM,Bizot MN,Dieterich HA,Howard D,Dole WP

更新日期：2008-03-01 00:00:00

abstract：:The influence of buflomedil on brain circulation was investigated in an open, preliminary trial in 12 patients with dementia caused by multi-cerebral infarcts. Patients were given 150 mg buflomedil 3-times daily for a period of 6 months. Assessments carried out before treatment included regional cerebral blood flow me...

journal_title：Current medical research and opinion

authors： Karoutas G,Milonas I,Artemis N,Karacostas D,Pitas J,Logothetis J

更新日期：1987-01-01 00:00:00

abstract：:Objectives Real-world patient outcomes data is scarce concerning the high disease burden of IBS-C. The aim of this study was to compare patient-reported symptom control, health-related quality of life (HRQoL), resource utilization, and treatment satisfaction of lubiprostone vs non-lubiprostone treatment for irritable ...

journal_title：Current medical research and opinion

authors： Solem CT,Patel H,Mehta S,Mody R,Macahilig C,Gao X

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Healthcare organizations must evaluate the cost effectiveness of the alternative therapies that are available to treat anemia and improve quality of life (QoL) of patients with cancer, that is, erythropoietic protein therapy and blood transfusion. METHODS:Pharmacoeconomic studies that evaluated the cost of ...

journal_title：Current medical research and opinion

authors： Cornes P,Coiffier B,Zambrowski JJ

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:In contrast to the trial design of acute mania studies, there is no standard design for bipolar maintenance studies. Over the past 15 years, the design of monotherapy maintenance studies in bipolar disorder has evolved significantly, but recent study designs continue to differ in important ways. SCOPE:We re...

journal_title：Current medical research and opinion

authors： Gitlin MJ,Abulseoud O,Frye MA

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:To determine the economic impact of sustained non-remission of depression on the total annual all-cause healthcare costs of patients with a history of depression. METHODS:Adults with ≥2 claims with depression diagnosis codes from the HealthCore Integrated Research Database were invited to participate in this...

journal_title：Current medical research and opinion

authors： Dennehy EB,Robinson RL,Stephenson JJ,Faries D,Grabner M,Palli SR,Stauffer VL,Marangell LB

更新日期：2015-06-01 00:00:00