Overactive bladder in women: symptom impact and treatment expectations.

abstract：:The effect of spironolactone in the alleviation of the symptoms of the premenstrual syndrome was compared with placebo in a double-blind, parallel group controlled study. One tablet daily of 100 mg spironolactone or placebo was given to 63 women from Day 12 of the menstrual cycle until the first day of the next menstr...

journal_title：Current medical research and opinion

authors： Vellacott ID,Shroff NE,Pearce MY,Stratford ME,Akbar FA

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the positive predictive value of claims-based V85 codes for identifying individuals with varying degrees of BMI relative to their measured BMI obtained from medical record abstraction. METHODS:This was a retrospective validation study utilizing administrative claims and medical chart data from 1 ...

journal_title：Current medical research and opinion

authors： Caplan EO,Kamble PS,Harvey RA,Smolarz BG,Renda A,Bouchard JR,Huang JC

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To analyze the construct validity of the EQ-5D in patients with acute coronary syndromes (ACS). METHODS:All ACS-diagnosed patients discharged from a university-affiliated hospital during a 3-year period were mailed a questionnaire that included the EQ-5D and the SF-8. The EQ-5D includes a visual analogue sca...

journal_title：Current medical research and opinion

authors： Ellis JJ,Eagle KA,Kline-Rogers EM,Erickson SR

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:Significant race and ethnic disparities exist in diabetes-related health care. Using a nationally representative database, we sought to determine if use of thiazolidinediones (TZDs) differs by race and ethnicity. As a secondary objective, we sought to determine if race and ethnicity is associated with use of ...

journal_title：Current medical research and opinion

authors： Aquilante CL,Zhang W,McCollum M

更新日期：2007-03-01 00:00:00

abstract：:Women who are diagnosed with early breast cancer remain at considerable risk of recurrence over the next several decades, even if their tumors were small and lymph nodes were negative, and despite receiving standard adjuvant therapy. A majority of breast cancers are hormone (estrogen) receptor-positive and amenable to...

journal_title：Current medical research and opinion

authors： Chowdhury S,Ellis P

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:We evaluated the clinical efficacy of sacubitril/valsartan in a group of ambulatory patients with heart failure (HF) with reduced ejection fraction (HFrEF) referred to our HF clinic. METHODS:Patients (n = 29; 72% males; mean age 76 years) with HFrEF in New York Heart Association (NYHA) classes II-III were in...

journal_title：Current medical research and opinion

authors： Cosentino ER,Degli Esposti D,Miceli R,Bentivenga C,Landolfo M,Fg Cicero A,Berardi E,Spinardi L,Magri G,Dugato V,Borghi C

更新日期：2019-03-01 00:00:00

abstract：:The GRASP (Global Research on Attitudes about hypertension and Stroke Prevention) survey, conducted in 11 countries and involving 825 physicians, was designed to investigate physician perceptions and priorities in the treatment of hypertension and influences on choice of antihypertensive therapy. The prevention of str...

journal_title：Current medical research and opinion

authors： Volpe M,Machado E

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:The epidemiology and outcome of people hospitalised with a primary diagnosis of psoriasis has never been characterised previously in the United Kingdom. The aim of the study was to characterise the epidemiology of people admitted to hospital with a primary diagnosis of psoriasis. METHODS:Routine hospital da...

journal_title：Current medical research and opinion

authors： Conway P,Currie CJ

更新日期：2008-12-01 00:00:00

abstract：:Aims: We sought to investigate the reasons for, and rates of, novel oral anticoagulant (DOAC) therapy discontinuation.Methods: This was an observational cohort study of patients with atrial fibrillation (AF) referred to a regional DOAC outpatient clinic between February 2013 and October 2017. The study population cons...

journal_title：Current medical research and opinion

authors： Mitrovic D,Folkeringa R,Veeger N,van Roon E

更新日期：2020-04-01 00:00:00

abstract：:Breast cancer was the focus of several presentations during the 27th European Society of Medical Oncology (ESMO) Congress held in Nice. Fulvestrant seems to be equally effective to tamoxifen as a first-line therapy in hormone-sensitive advanced breast cancer in postmenopausal women. However, it may be more effective t...

journal_title：Current medical research and opinion

authors： Mokbel K

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To investigate whether once daily biphasic insulin aspart 30 (BIAsp 30) is noninferior to once daily insulin glargine (IGlar) among Chinese and Japanese insulin-naïve subjects with type 2 diabetes mellitus (T2DM). RESEARCH DESIGN AND METHODS:This was a 24 week treat-to-target trial (NCT01123980) that include...

journal_title：Current medical research and opinion

authors： Yang W,Xu X,Liu X,Yang G,Seino Y,Andersen H,Jinnouchi H

更新日期：2013-12-01 00:00:00

abstract：:In a multi-centre study, the antidepressant efficacy and incidence of on-therapy events of trazodone (100 to 400 mg daily) and mianserin (30 to 120 mg daily) was compared using a double-blind pre-determined randomized parallel group design in depressed patients unresponsive to placebo after a 7-day screening period. O...

journal_title：Current medical research and opinion

authors： Bennie EH,Khan MC,Tyrer SP,Siddiqui U,Ankier SI

更新日期：1984-01-01 00:00:00

abstract：UNLABELLED:The occurrence of intestinal bacterial overgrowth in patients with Crohn's Disease (CD) has been described and antimicrobial treatment has been shown to be effective in reversing this condition. However, the mechanisms underlying the efficacy of antimicrobial therapy are still only partially known. The aim o...

journal_title：Current medical research and opinion

authors： Biancone L,Vernia P,Agostini D,Ferrieri A,Pallone F

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Modern immunology has been extremely successful in elucidating many features of the immune system, but not in stemming pandemics of non-infectious, immune-related disease associated with industrialized populations. These pandemics involve a broad range of allergic, autoimmune, and inflammatory diseases, poten...

journal_title：Current medical research and opinion

authors： Parker W,Perkins SE,Harker M,Muehlenbein MP

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:Tumor necrosis factor (TNF) antagonists, most frequently prescribed biologics for moderate to severe rheumatoid arthritis (RA), are subject to dose escalation. Even though different methods have been employed to estimate the timing and magnitude of dose escalation, there is no consensus on which method is op...

journal_title：Current medical research and opinion

authors： Huang X,Gu NY,Fox KM,Harrison DJ,Globe D

更新日期：2010-07-01 00:00:00

abstract：:An open clinical evaluation was carried out in 736 African out-patients suffering from rheumatic and inflammatory disorders to assess the efficacy and tolerability of tenoxicam in relieving the signs and symptoms of their condition. On entry, all previous treatment was discontinued and patients received a simple daily...

journal_title：Current medical research and opinion

authors： Ibrahima K,Kodjo G,Issa S,Seye L,Cisse F,Eassey G,Rietiker S

更新日期：1991-01-01 00:00:00

abstract：:The manifestation of pain in any individual patient may result from a variety of underlying mechanisms that also may vary from one disease state to another. Global measures of pain intensity and relief are inadequate for characterizing specific pain qualities or identifying the unique effects of pain treatments on dif...

journal_title：Current medical research and opinion

authors： Jensen MP

更新日期：2004-01-01 00:00:00

abstract：:Evidence from randomized, placebo-controlled, double-masked studies has demonstrated that verteporfin (Visudyne) therapy is effective in reducing the risk of visual acuity loss in selected groups of patients with choroidal neovascularization (CNV) due to age-related macular degeneration (AMD). Pilot studies of intravi...

journal_title：Current medical research and opinion

authors： Kaiser PK

更新日期：2005-05-01 00:00:00

abstract：:Fifty-two patients suffering from presumed viral pharyngeal infection or tonsillitis were treated with either benzydamine or placebo oral rinse as a gargle at 3-hourly intervals in a randomized double-blind study. Patients on the active preparation experienced faster resolution of pain and dysphagia and at 7 days 88% ...

journal_title：Current medical research and opinion

authors： Whiteside MW

更新日期：1982-01-01 00:00:00

abstract：:A clinical trial was undertaken in 50 patients with osteoarthritis of the knee to assess the therapeutic value of glycosaminoglycan-peptide complex in treatment. The first year consisted of a randomized, double-blind, placebo-controlled, parallel-group trial (25 patients in each group), after which all patients receiv...

journal_title：Current medical research and opinion

authors： Katona G

更新日期：1987-01-01 00:00:00

abstract：:Background: Actinic keratosis (AK) is considered an "in situ" non-melanoma skin cancer induced by ultraviolet chronic exposure. Sunscreen and topical anti-inflammatory agents like diclofenac could improve the evolution of this kind of lesions. A topical product containing piroxicam 0.8% and sun filters (50 SPF) (ACTX)...

journal_title：Current medical research and opinion

authors： Agozzino M,Russo T,Franceschini C,Mazzilli S,Garofalo V,Campione E,Bianchi L,Milani M,Argenziano G

更新日期：2019-10-01 00:00:00

abstract：:Abstract Recent guidelines recommend strict goals for low-density lipoprotein cholesterol (LDL-C) (1.8-2.6 mmol/L; 70-100 mg/dL). However, these goals are not always met and many primary and secondary prevention patients are not optimally controlled. Both the under-prescription of lipid-lowering medication and lack of...

journal_title：Current medical research and opinion

authors： Daskalopoulou SS,Doonan RJ,Mikhailidis DP

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase 4 (DPP4) inhibitors are currently used as glucose-lowering agents in type 2 diabetes, due to their effects on insulin and glucagon secretion. These agents, which are effective in improving glucose control, could also have a beneficial...

journal_title：Current medical research and opinion

authors： Mannucci E,Dicembrini I

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:Pioglitazone hydrochloride (Actos † ) and rosiglitazone maleate (Avandia ‡ ) are members of the thiazolidinedione (TZD) class of oral anti-diabetic drugs (OADs) and are used to treat type 2 diabetes mellitus (T2DM). Greater beneficial effects on lipids have been demonstrated with pioglitazone, however. Study...

journal_title：Current medical research and opinion

authors： Tunis SL,Minshall ME,St Charles M,Pandya BJ,Baran RW

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:To further assess the clinically active dose range of etoricoxib, a COX-2 selective inhibitor, in rheumatoid arthritis (RA). METHODS:RA patients were randomized to etoricoxib 10, 30, 60, or 90 mg or placebo in a double-blind, 12-week study. DMARDs (methotrexate, biologics) or low-dose corticosteroids were al...

journal_title：Current medical research and opinion

authors： Greenwald M,Peloso PM,Mandel D,Soto O,Mehta A,Frontera N,Boice JA,Zhan XJ,Curtis SP

更新日期：2011-10-01 00:00:00

abstract：:A total of 247 patients suffering from rheumatoid arthritis and allied conditions were referred for routine ophthalmological examination with particular reference to ocular rheumatoid involvement. Of these, 197 were already receiving ibuprofen before their first assessment while 50 had a baseline assessment before com...

journal_title：Current medical research and opinion

authors： Williamson J,Sturrock RD

更新日期：1976-01-01 00:00:00

abstract：:A randomized study was performed on 24 patients with ankylosing spondylitis to compare the efficacy and tolerability of 20 mg tenoxicam daily with 50 mg diclofenac twice daily. There were 6 withdrawals from the group taking tenoxicam and 4 from the diclofenac group. Depression in 1 patient taking tenoxicam was the onl...

journal_title：Current medical research and opinion

authors： Schwarzer AC,Cohen M,Arnold MH,Kelly D,McNaught P,Brooks PM

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:To compare 1-year direct healthcare costs and utilization among children and adolescents initiating non-stimulant medications atomoxetine (ATX) or extended-release guanfacine (GXR). METHODS:In this retrospective, observational cohort study, children and adolescents aged 6-17 years with attention deficit/hyp...

journal_title：Current medical research and opinion

authors： Molife C,Haynes VS,Nyhuis A,Faries DE,Gelwicks S,Kelsey DK,Alatorre CI

更新日期：2018-04-01 00:00:00

abstract：:Control of hypertension is hindered by the incidence of adverse events associated with therapy, which can result in low patient compliance. Specific angiotensin II receptor subtype AT1 blockers offer an alternative to the angiotensin converting enzyme inhibitors in the treatment of hypertension, as the incidence of si...

journal_title：Current medical research and opinion

authors： Levine B

更新日期：2001-01-01 00:00:00

abstract：:An investigator-blind, parallel-group, multicentre study was undertaken to compare the efficacy and tolerability of once-daily, sustained-release (s-r) ibuprofen and diclofenac sodium in patients (mean age 59.8 years) suffering from painful osteoarthritis affecting chiefly the knee and/or hip. Patients attending eight...

journal_title：Current medical research and opinion

authors： Baumgartner H,Schwarz HA,Blum W,Bruhin A,Gallachi G,Goldinger G,Saxer M,Trost H

更新日期：1996-01-01 00:00:00