Comparison of trazodone and mianserin in depressive illness.

abstract：:Migraine is a very common disorder, affecting about 11% of adult populations in Western countries. Prevalence is highest during the peak productive years--between the ages of 25 and 55. The prevalence is higher in females than males at all post-pubertal ages, but the sex ratio varies with age. In the United States, mi...

journal_title：Current medical research and opinion

authors： Lipton RB,Stewart WF,Scher AI

更新日期：2001-01-01 00:00:00

abstract：:A study was carried out to determine the efficacy and long-term safety of dantrolene in treating stroke patients with spasticity limiting rehabilitation. Fifteen of the 18 patients studied experienced reduction in spasticity and clinical improvement after treatment with dantrolene sodium for 6 weeks. Fourteen of these...

journal_title：Current medical research and opinion

authors： Ketel WB,Kolb ME

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:The prevalence of non-steroidal anti-inflammatory drug (NSAID) and concurrent gastroprotective agent (GPA) use in the US is not known. As such, the prevalence of GPA use among arthritis patients taking NSAIDs was examined. METHODS:Men and women aged ≥ 40 with self-reported arthritis and members of a web-base...

journal_title：Current medical research and opinion

authors： Coyne KS,Margolis MK,Cappelleri JC,Hsieh R,Essex MN,Park PW,Joshi AV

更新日期：2013-05-01 00:00:00

abstract：:Objective: To review the mechanism of action, pharmacology, dosing, and complications of tranexamic acid (TXA) and consolidate current evidence for TXA in gynecologic surgery.Methods: A literature search of PubMed, Ovid (MEDLINE), Google Scholar, and Elsevier was performed, in addition to a targeted search of cited re...

journal_title：Current medical research and opinion

authors： Zakhari A,Sanders AP,Solnik MJ

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:The injection force and the patient perception of the Next Generation FlexPen (NGFP) with design modifications aimed at reducing injection force was assessed. The accuracy and precision of the NGFP was also tested under standard conditions. RESEARCH DESIGN AND METHODS:Dosing accuracy was tested (according to...

journal_title：Current medical research and opinion

authors： Pfützner A,Reimer T,Hohberg C,Frøkjaer LP,Jørgensen C

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To evaluate costs associated with prostaglandin analogs among newly-diagnosed glaucoma patients in a managed-care population. RESEARCH DESIGN AND METHODS:A cost minimization model compared annual costs for patients initiating therapy with one of the three prostaglandin analogs (bimatoprost, latanoprost, trav...

journal_title：Current medical research and opinion

authors： Schmier JK,Covert DW,Robin AL

更新日期：2007-11-01 00:00:00

abstract：:In a single-blind study in general practice, 60 patients with anxiety neuroses were randomly allocated to receive either 0.5 mg haloperidol twice daily or 2 mg diazepam 3-times daily for 6 weeks. Eighteen patients (6 on haloperidol and 12 on diazepam) were excluded from the analysis of efficacy. On the Hamilton Rating...

journal_title：Current medical research and opinion

authors： Budden MG

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:Acute postprandial hyperglycemia (aPPHG) is often symptomatic and can be associated with behavioral changes such as impaired working memory and attention. However, there is little evidence of the impact of aPPHG on the daily lives of patients. The aim of this study was to explore the frequency and severity of...

journal_title：Current medical research and opinion

authors： Heller S,Meneghini L,Nikolajsen A,Kragh N,Lewis HB,Saretsky T,Kosmas CE,Lloyd A

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To compare the efficacy and safety of the concomitant administration of travoprost 0.004% once daily and brinzolamide 0.1% twice daily with those of a fixed combination of latanoprost 0.005%/timolol 0.5% once daily. RESEARCH, DESIGN AND METHODS:Forty-four patients with primary open-angle glaucoma or ocular hyp...

journal_title：Current medical research and opinion

authors： Martinez-de-la-Casa JM,Castillo A,Garcia-Feijoo J,Mendez-Hernandez C,Fernandez-Vidal A,Garcia-Sanchez J

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:The management of iron-deficiency anaemia in patients with non-dialysis chronic kidney disease (ND-CKD) remains controversial, particularly regarding the use of oral versus intravenous iron supplementation. METHODS:A PubMed search from 1970 to February 2009 was conducted to identify relevant research articl...

journal_title：Current medical research and opinion

authors： Macdougall IC

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Painful physical symptoms are common in patients with major depressive disorder (MDD) and can negatively affect patient outcomes. Duloxetine has demonstrated efficacy in treating MDD and other certain painful conditions; this study specifically evaluated patients with both MDD and MDD-associated pain. METHOD...

journal_title：Current medical research and opinion

authors： Gaynor PJ,Gopal M,Zheng W,Martinez JM,Robinson MJ,Hann D,Marangell LB

更新日期：2011-10-01 00:00:00

abstract：:Normalizing serum thyroid stimulating hormone (TSH) levels by lifelong treatment with levothyroxine (LT4) remains the primary goal of therapy for patients with hypothyroidism. The reference ranges for TSH are derived from populations with (supposedly) normal thyroid function. But, TSH results are affected by a number ...

journal_title：Current medical research and opinion

authors： Razvi S,Hostalek U

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Based on the clear neuroanatomical delineation of many neuropathic pain (NP) symptoms, a simple tool for performing a short structured clinical encounter based on the IASP diagnostic criteria was developed to identify NP. This study evaluated its accuracy and usefulness. METHODS:A case-control study was perf...

journal_title：Current medical research and opinion

authors： Mayoral V,Pérez-Hernández C,Muro I,Leal A,Villoria J,Esquivias A

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:A proactive, multifactorial intervention strategy incorporating single-pill amlodipine/atorvastatin (SPAA) (5-10/10 mg up-titrated to 5-10/20 mg, where approved) is more effective than physician's usual care (UC) for reducing calculated 10 year coronary heart disease (CHD) risk, in patients with hypertension ...

journal_title：Current medical research and opinion

authors： Hradec J,Zamorano J,Sutradhar S

更新日期：2013-06-01 00:00:00

abstract：:Objectives: Asthma/chronic obstructive pulmonary disease (COPD) overlap (ACO) is a recently described phenomenon defined as the coexistence of both asthma and COPD. Both asthma and COPD are known to result in increased emergency department (ED) visits and hospitalizations, but it is unclear how the ACO population util...

journal_title：Current medical research and opinion

authors： Kim M,Tillis W,Patel P,Davis RM,Asche CV

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare the efficacy and safety of doses of fentanyl buccal tablet (FBT) proportional to doses of opioids used for background analgesia versus dose titration starting with the minimal dose for the management of breakthrough cancer pain (BTcP). METHODS:A total of 82 cancer patien...

journal_title：Current medical research and opinion

authors： Mercadante S,Gatti A,Porzio G,Lo Presti C,Aielli F,Adile C,Casuccio A

更新日期：2012-06-01 00:00:00

abstract：:Liver transplantation is currently a standard therapy for patients with end-stage liver diseases and hepatocellular carcinoma. Given that liver transplantation has undergone a thriving development in these decades, the survival rates after liver transplantation have markedly improved as a result of the critical advanc...

journal_title：Current medical research and opinion

authors： Mu J,Chen Q,Zhu L,Wu Y,Liu S,Zhao Y,Ma T

更新日期：2019-02-01 00:00:00

abstract：:The therapeutic efficacy of 100 mg spironolactone once daily in patients with congestive heart failure was evaluated in a multi-centre study in general practice. One hundred and fifteen patients were admitted to the study. Clinical and haemotological assessments were made at entry and at regular intervals throughout t...

journal_title：Current medical research and opinion

authors： Smith AG

更新日期：1980-01-01 00:00:00

abstract：:Oesophageal mucosa has well established protective mechanisms, which operate within pre-epithelial, epithelial and post-epithelial compartments. Since refluxed acid and pepsin always act from the luminal side of the mucosa, protective factors like EGF, operating as a part of pre-epithelial defence, are thought to be p...

journal_title：Current medical research and opinion

authors： Marcinkiewicz M,Grabowska SZ,Czyzewska E

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:To quantify changes in clinical and cost outcomes associated with increasing levels of body mass index (BMI) in a US setting. RESEARCH METHODS AND PROCEDURES:A semi-Markov model was developed to project and compare life expectancy (LE), quality-adjusted life expectancy (QALE) and direct medical costs associa...

journal_title：Current medical research and opinion

authors： Tucker DM,Palmer AJ,Valentine WJ,Roze S,Ray JA

更新日期：2006-03-01 00:00:00

abstract：:A double-blind crossover study was carried out in 21 patients with osteoarthrosis of the hip to compare the effectiveness and tolerance of 1200 mg tolmetin sodium daily with 75 mg indomethacin daily. Each drug was given in 3 equally divided doses daily for a period of 2 weeks, both active treatment periods being prece...

journal_title：Current medical research and opinion

authors： Davies J,Dixon AS,Steele CE

更新日期：1980-01-01 00:00:00

abstract：:Recombinant human erythropoietin (epoetin) is a highly active molecule and as such is used at very low therapeutic concentrations that require stabilisation. Commercially available epoetins differ in the stabilisers used in their formulations, which result in variations between epoetin preparations in storage and hand...

journal_title：Current medical research and opinion

authors： Haselbeck A

更新日期：2003-01-01 00:00:00

abstract：:Quetiapine fumarate is a novel dibenzothiazepine antipsychotic developed by Zeneca. It is marketed under the trade name 'Seroquel'. Quetiapine is well tolerated and clinically effective in the treatment of schizophrenia. The initial hope of investigators was that quetiapine would have antipsychotic potential and that ...

journal_title：Current medical research and opinion

authors： Green B

更新日期：1999-01-01 00:00:00

abstract：:A total of 247 patients suffering from rheumatoid arthritis and allied conditions were referred for routine ophthalmological examination with particular reference to ocular rheumatoid involvement. Of these, 197 were already receiving ibuprofen before their first assessment while 50 had a baseline assessment before com...

journal_title：Current medical research and opinion

authors： Williamson J,Sturrock RD

更新日期：1976-01-01 00:00:00

abstract：:Objectives: Atopic dermatitis (AD) is a chronic, relapsing skin condition, with signs and symptoms that impact patients' lives and are best measured from the patient perspective. Therefore, there is a need for AD-specific questionnaires that are consistent with Food and Drug Administration guidance and best measuremen...

journal_title：Current medical research and opinion

authors： Foley C,Tundia N,Simpson E,Teixeira HD,Litcher-Kelly L,Bodhani A

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To examine the impact of an electronic data capture system on patient satisfaction and patient-physician interactions in a rheumatology clinical setting. STUDY DESIGN:In this multicenter study, 1079 patients with rheumatoid arthritis completed questionnaires quarterly about their health and satisfaction with...

journal_title：Current medical research and opinion

authors： Huffstutter J,Craig WD,Schimizzi G,Harshbarger J,Lisse J,Kasle S,Hymson L,Yocum D,Castro L,Hegedus R,Callegari P,Yeilding N,Gilmer K

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:We evaluated the clinical efficacy of sacubitril/valsartan in a group of ambulatory patients with heart failure (HF) with reduced ejection fraction (HFrEF) referred to our HF clinic. METHODS:Patients (n = 29; 72% males; mean age 76 years) with HFrEF in New York Heart Association (NYHA) classes II-III were in...

journal_title：Current medical research and opinion

authors： Cosentino ER,Degli Esposti D,Miceli R,Bentivenga C,Landolfo M,Fg Cicero A,Berardi E,Spinardi L,Magri G,Dugato V,Borghi C

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:There is growing evidence describing DNA repair genes polymorphisms are related to increased cancer risk including colorectal cancer (CRC). The aim of this study was to investigate the associations between the APE1 Asp148Glu, hOGG1 Ser326Cys, XRCC1 Arg399Gln, XRCC3 Thr241Met, XPD Lys751Gln, XPG Asp1104His po...

journal_title：Current medical research and opinion

authors： Canbay E,Cakmakoglu B,Zeybek U,Sozen S,Cacina C,Gulluoglu M,Balik E,Bulut T,Yamaner S,Bugra D

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Fibromyalgia (FM) is characterized by persistent and widespread pain and often associated with other symptoms and comorbidities. Thus, FM patients seek care from multiple physician specialties. This study compared prescribing patterns, patient-reported outcomes (PROs), healthcare resource use (HRU), and dire...

journal_title：Current medical research and opinion

authors： McNett M,Goldenberg D,Schaefer C,Hufstader M,Baik R,Chandran A,Zlateva G

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:To describe multiple myeloma (MM) treatment patterns and comorbidities over time in the US. RESEARCH DESIGN AND METHODS:Study patients were newly diagnosed with MM (ICD-9-CM 203.0x) between 1 July 2006 and 31 March 2014 and had ≥6 months of data prior to the initial MM diagnosis in MarketScan Research Datab...

journal_title：Current medical research and opinion

authors： Song X,Cong Z,Wilson K

更新日期：2016-01-01 00:00:00