Tolmetin sodium and indomethacin in the treatment of osteoarthrosis of the hip: a double-blind crossover study.

abstract：:Daily fluctuations in plasma cortisol levels were studied in three groups of children with rheumatoid arthritis. One group was untreated with hormones, the second treated with a depot preparation of tetracosactrin, and the third group with corticosteroid hormones. The results obtained were compared with the rhythm in ...

journal_title：Current medical research and opinion

authors： Tsvetkova V

更新日期：1977-01-01 00:00:00

abstract：:A randomized, double-blind study was carried out in 24 patients with stable angina pectoris to compare the efficacy of nadolol, a new beta-adrenoceptor antagonist, and propranolol. After a period on placebo, 14 patients received nadolol once daily and 10 patients propranolol 4-times daily over a 10-week dose-ranging p...

journal_title：Current medical research and opinion

authors： Furberg B,Dahlqvist A,Raak A,Wrege U

更新日期：1978-01-01 00:00:00

abstract：OBJECTIVE:Neurogenic bladder refers to morphofunctional alterations of the bladder-sphincter complex secondary to central or peripheral neurological lesions. Discal etiology can be suggested by clinical observation in patients complaining of classical lower back pain, but not excluded even without musculoskeletal pain....

journal_title：Current medical research and opinion

authors： Siracusa G,Sparacino A,Lentini VL

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:We sought to evaluate the relationship between different levels of medication possession ratio (MPR) attained and achievement of clinically meaningful reductions in lipid levels. RESEARCH DESIGN AND METHODS:This was a retrospective cohort study of 4691 new statin users from the Department of Veteran Affairs ...

journal_title：Current medical research and opinion

authors： Watanabe JH,Bounthavong M,Chen T

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Obesity is one of the major problems of health policy in different countries. Pharmacological attempts have been made to help affected people without a definitive solution. Some agents--either with peripheral or central effect--are available in the market. On July 2012, the FDA approved two novel preparation...

journal_title：Current medical research and opinion

authors： Catoira NP,Viale L,Di Girolamo G,Gonzalez C

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:It has been acknowledged that patients who receive a beta-blocker or diuretic based regimen are at increased risk of developing new-onset diabetes. Recently, angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) have been shown to decrease patients' odds of developing new-o...

journal_title：Current medical research and opinion

authors： Kuti EL,Baker WL,White CM

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:To assess the burden of treatment-resistant depression (TRD) among privately insured patients with anxiety disorder and/or substance use disorders (SUD). METHODS:Adults <65 years old were identified in the Optum Health Care Solutions Inc. database (July 2009-March 2017). Among those with major depressive dis...

journal_title：Current medical research and opinion

authors： Zhdanava M,Kuvadia H,Joshi K,Daly E,Pilon D,Rossi C,Morrison L,Lefebvre P,Nelson C

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Latinos are the largest minority population in the United States, and are characterized by higher rates of obesity and diabetes compared to Whites. The prevalence of diagnosed diabetes in Latinos is two-fold higher than in Caucasians, and Latinos suffer from higher rates of diabetic complications and mortali...

journal_title：Current medical research and opinion

authors： Gonzalez AB,Salas D,Umpierrez GE

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:Pharmaceutical preparations of human menopausal gonadotrophin (hMG), urine-derived follicle-stimulating hormone (u-FSH) and highly purified u-FSH (u-FSH-HP) have been available since the early 1960s and the mid 1980s and 1990s, respectively. Another commercial preparation of u-FSH-HP, Folyrmon P, was launched...

journal_title：Current medical research and opinion

authors： Bassett R,Ceccarelli D,Crisci C,di Tria AM,Mancinelli M,Martelli F,Mendola D,Pezzotti A

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:To evaluate costs associated with prostaglandin analogs among newly-diagnosed glaucoma patients in a managed-care population. RESEARCH DESIGN AND METHODS:A cost minimization model compared annual costs for patients initiating therapy with one of the three prostaglandin analogs (bimatoprost, latanoprost, trav...

journal_title：Current medical research and opinion

authors： Schmier JK,Covert DW,Robin AL

更新日期：2007-11-01 00:00:00

abstract：:A study was carried out in general practice to assess the clinical effectiveness and tolerability of the oral cephalosporin, cefuroxime axetil, in the treatment of 369 patients presenting with acute infections of the upper respiratory tract. The main diagnoses were tonsillitis, pharyngitis, sinusitis and otitis media....

journal_title：Current medical research and opinion

authors： Griffiths GK,VandenBurg MJ,Wight LJ,Gudgeon AC,Kelsey M

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to analyze the characteristics and costs of exogenous endoscopy-related infections, pseudo-infections, and toxic reactions in the US. METHODS:A systematic review of the scientific literature published between 1966 and 2005 was conducted in Medline. Data collection was based o...

journal_title：Current medical research and opinion

authors： Seoane-Vazquez E,Rodriguez-Monguio R,Visaria J,Carlson A

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:In contrast to the trial design of acute mania studies, there is no standard design for bipolar maintenance studies. Over the past 15 years, the design of monotherapy maintenance studies in bipolar disorder has evolved significantly, but recent study designs continue to differ in important ways. SCOPE:We re...

journal_title：Current medical research and opinion

authors： Gitlin MJ,Abulseoud O,Frye MA

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to provide a comprehensive estimate of the cost of ADHD by consider ing the healthcare and work loss costs of persons with ADHD, as well as those costs imposed on their family members. METHODS:Excess per capita healthcare (medical and prescription drug) and work loss (disabilit...

journal_title：Current medical research and opinion

authors： Birnbaum HG,Kessler RC,Lowe SW,Secnik K,Greenberg PE,Leong SA,Swensen AR

更新日期：2005-02-01 00:00:00

abstract：:Objective: The aim of this study was to investigate the impact of methodological choices in a meta-analysis of real-world evidence (RWE) comparing three non-vitamin-K antagonist oral anticoagulants with vitamin K antagonists (VKAs) for the treatment of patients with non-valvular atrial fibrillation (NVAF). Methods: Th...

journal_title：Current medical research and opinion

authors： Briere JB,Wu O,Bowrin K,Millier A,Toumi M,Taieb V,Levy P,Coleman CI

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To review published evidence on the impact of weight/BMI change on health-related quality of life (HRQoL) in adults from the US with overweight/obesity. METHODS:The systematic review was conducted in accordance with PRISMA guidelines. MEDLINE, Embase, EconLit, and Cochrane Library databases were reviewed usi...

journal_title：Current medical research and opinion

authors： Kroes M,Osei-Assibey G,Baker-Searle R,Huang J

更新日期：2016-01-01 00:00:00

abstract：:A single-blind, open-label controlled study was carried out in 30 healthy male volunteers to compare gastro-intestinal blood loss before, during and after treatment with a new, sustained-release formulation of the non-steroidal anti-inflammatory agent etodolac (etodolac SR) or with naproxen. Subjects remained at the s...

journal_title：Current medical research and opinion

authors： Leese P

更新日期：1992-01-01 00:00:00

abstract：:An open multicentre trial was carried out in 13 hypertensive patients, who had responded satisfactorily to and been stabilized on treatment with 400 mg acebutolol daily in divided doses, to assess the effectiveness and tolerance of the same daily dosage given as a single morning dose. On admission, patients were chang...

journal_title：Current medical research and opinion

authors： Ashton WL

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:To determine the efficacy and safety of lumiracoxib for knee osteoarthritis (OA). METHODS:This was a 13-week, multicentre, randomized, double-blind, double-dummy, placebo-controlled study. Males or females aged >/= 18 years with primary knee OA received lumiracoxib 100 mg od, lumiracoxib 100 mg od with a loa...

journal_title：Current medical research and opinion

authors： Lehmann R,Brzosko M,Kopsa P,Nischik R,Kreisse A,Thurston H,Litschig S,Sloan VS

更新日期：2005-04-01 00:00:00

abstract：:Background: Actinic keratosis (AK) is considered an "in situ" non-melanoma skin cancer induced by ultraviolet chronic exposure. Sunscreen and topical anti-inflammatory agents like diclofenac could improve the evolution of this kind of lesions. A topical product containing piroxicam 0.8% and sun filters (50 SPF) (ACTX)...

journal_title：Current medical research and opinion

authors： Agozzino M,Russo T,Franceschini C,Mazzilli S,Garofalo V,Campione E,Bianchi L,Milani M,Argenziano G

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Transient ischemic attack (TIA) is a serious condition which should be considered on the same spectrum as other conditions involving brain ischemia. Efficient management of these patients is therefore critical. The aim of this research was to gain insights into 'real-world' global trends of the current manage...

journal_title：Current medical research and opinion

authors： Jäkel A,Plested M,Chapman AM,Jackson D,Purroy F

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:Painful physical symptoms are common in patients with major depressive disorder (MDD) and can negatively affect patient outcomes. Duloxetine has demonstrated efficacy in treating MDD and other certain painful conditions; this study specifically evaluated patients with both MDD and MDD-associated pain. METHOD...

journal_title：Current medical research and opinion

authors： Gaynor PJ,Gopal M,Zheng W,Martinez JM,Robinson MJ,Hann D,Marangell LB

更新日期：2011-10-01 00:00:00

abstract：:Historically, the approach to atherogenesis research has been focused on factors that primarily include vessel wall histology, blood and vessel wall biochemistry, clotting factors and platelets. This approach can be referred to as the 'biochemical' approach. We now recognize that atherosclerosis is an ongoing sterile ...

journal_title：Current medical research and opinion

authors： Kensey KR

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Aripiprazole differs from other atypical antipsychotics in its pharmacological and clinical profile. SCOPE:As aripiprazole has been available in the USA for bipolar mania since 2004, clinical experience-sharing from clinical and research use of this agent can assist with initiation and administration in pra...

journal_title：Current medical research and opinion

authors： Fagiolini A

更新日期：2008-09-01 00:00:00

abstract：:In a double-blind, partial cross-over study of 141 patients with mild to moderate hypertension, chlorthalidone 50 mg was compared with chlorthalidone 50 mg/triamterene 50 mg combination treatment. The study assessed clinical efficacy in the reduction of blood pressure, and safety with regard to serum potassium concent...

journal_title：Current medical research and opinion

authors： Spiers DR,Wade RC

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:To report the long-term effect of the dorzolamide/timolol (DTFC) and latanoprost/timolol (LTFC) fixed combinations on intraocular pressure (IOP) and visual field defects over time in naïve primary open-angle glaucoma (POAG) patients. STUDY DESIGN AND METHODS:Prospective, 4-year, open-label, interventional st...

journal_title：Current medical research and opinion

authors： Pajic B,Pajic-Eggspuehler B,Häfliger IO

更新日期：2010-09-01 00:00:00

abstract：INTRODUCTION:This subanalysis compared the efficacy of betahistine plus piracetam dual therapy versus betahistine monotherapy using data from OSVaLD, a 3 month, open-label, observational study conducted in 2272 patients with peripheral vestibular vertigo. Of the 1898 patients included in the original efficacy populatio...

journal_title：Current medical research and opinion

authors： Melnikov OA,Lilenko SV,Nauta J,Ouwens MJ

更新日期：2015-11-01 00:00:00

abstract：:An open, multi-centre study was carried out in 117 pregnant women presenting with vaginal candidosis to assess the effectiveness of econazole in providing mycological control and symptom relief, and in preventing, as far as possible, the risk of contamination of the newborn: nearly 50% of the patients were in the last...

journal_title：Current medical research and opinion

authors： Goormans E,Beek JM,Declercq JA,Loendersloot EW,Roelofs HJ,van Zanten A

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To further assess the clinically active dose range of etoricoxib, a COX-2 selective inhibitor, in rheumatoid arthritis (RA). METHODS:RA patients were randomized to etoricoxib 10, 30, 60, or 90 mg or placebo in a double-blind, 12-week study. DMARDs (methotrexate, biologics) or low-dose corticosteroids were al...

journal_title：Current medical research and opinion

authors： Greenwald M,Peloso PM,Mandel D,Soto O,Mehta A,Frontera N,Boice JA,Zhan XJ,Curtis SP

更新日期：2011-10-01 00:00:00

abstract：:A double-blind, placebo-controlled study was carried out in 231 adult patients suffering from acute diffuse pharyngitis or acute tonsillitis with fever and dysphagia to assess the effectiveness of niflumic acid combined with standard antibiotic therapy in relieving pain and inflammation. Patients were allocated at ran...

journal_title：Current medical research and opinion

authors： Sauvage JP,Ditisheim A,Bessede JP,David N

更新日期：1990-01-01 00:00:00