Influence of gut microbiota and intestinal barrier on enterogenic infection after liver transplantation.

abstract：BACKGROUND:Lowering intraocular pressure (IOP) is currently the only therapeutic approach that preserves visual function in primary open-angle glaucoma. In making treatment decisions for first- and second-line therapy, the clinician needs to provide an appropriate balance of efficacy and tolerability. Prostaglandin ana...

journal_title：Current medical research and opinion

authors： Aptel F,Denis P

更新日期：2011-10-01 00:00:00

abstract：:The effects of xipamid and frusemide were comapred in 9 oedematous patients. Xipamid was found to be equipotent with frusemide in doses of 40 mg. and 80 mg., with respect to its effect on sodium and water excretion. The time course of action of xipamid was observed to be more prolonged than that of frusemide. It is co...

journal_title：Current medical research and opinion

authors： Piyasena KH,Havard CW,Weber JC

更新日期：1975-01-01 00:00:00

abstract：OBJECTIVE:To assess the burden of treatment-resistant depression (TRD) among privately insured patients with anxiety disorder and/or substance use disorders (SUD). METHODS:Adults <65 years old were identified in the Optum Health Care Solutions Inc. database (July 2009-March 2017). Among those with major depressive dis...

journal_title：Current medical research and opinion

authors： Zhdanava M,Kuvadia H,Joshi K,Daly E,Pilon D,Rossi C,Morrison L,Lefebvre P,Nelson C

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Reduction in total cholesterol (TC) and LDL-cholesterol (LDL-C) forms one of the principal objectives of most cardiovascular secondary prevention strategies. Many patients being treated with statins, however, have significant residual dyslipidaemia, with many having suboptimal HDL-cholesterol ...

journal_title：Current medical research and opinion

authors： Belsey J,de Lusignan S,van Vlymen J,Chan T,Hague N

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Generic drugs are identical or bioequivalent versions of the brand name drugs. They are the economic alternative of the costlier brand name drugs. This article presents a general overview of the procedure and regulatory aspects relating to generic drug approval in the US. METHODS:A computerized search was co...

journal_title：Current medical research and opinion

authors： Nagori BP,Mathur V,Garg S

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare the efficacy and safety of doses of fentanyl buccal tablet (FBT) proportional to doses of opioids used for background analgesia versus dose titration starting with the minimal dose for the management of breakthrough cancer pain (BTcP). METHODS:A total of 82 cancer patien...

journal_title：Current medical research and opinion

authors： Mercadante S,Gatti A,Porzio G,Lo Presti C,Aielli F,Adile C,Casuccio A

更新日期：2012-06-01 00:00:00

abstract：:An open, multi-centre, non-comparative study was carried out in general practice to assess the efficacy and tolerance of piroxicam in 159 patients with osteoarthritis and 27 patients with rheumatoid arthritis. Initial dosage ranged from 10 to 40 mg piroxicam and all but a few patients continued treatment with 20 mg on...

journal_title：Current medical research and opinion

authors： Gow PJ

更新日期：1983-01-01 00:00:00

abstract：:Understanding of the damaging effects of significance testing has steadily grown. Reporting p values without dichotomizing the result to be significant or not, is not the solution. Confidence intervals are better, but are troubled by a non-intuitive interpretation, and are often misused just to see whether the null va...

journal_title：Current medical research and opinion

authors： The B

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To estimate the costs and consequences of using pamidronate compared to zoledronic acid in the prophylactic management of skeletal morbidity among breast cancer patients in the UK. DESIGN AND SETTING:This was a modelling study performed from the perspective of the UK's National Health Service (NHS). METHODS...

journal_title：Current medical research and opinion

authors： Guest JF,Clegg JP,Davie AM,McCloskey E

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Obesity is one of the major problems of health policy in different countries. Pharmacological attempts have been made to help affected people without a definitive solution. Some agents--either with peripheral or central effect--are available in the market. On July 2012, the FDA approved two novel preparation...

journal_title：Current medical research and opinion

authors： Catoira NP,Viale L,Di Girolamo G,Gonzalez C

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:Although a reduced aflibercept (2.0 mg) injection frequency relative to the approved dosing posology is included in national treatment guidelines for wet age-related macular degeneration (AMD), there is limited evidence of its comparative efficacy. The objective was to compare the efficacy and safety of reduc...

journal_title：Current medical research and opinion

authors： Szabo SM,Hedegaard M,Chan K,Thorlund K,Christensen R,Vorum H,Jansen JP

更新日期：2015-11-01 00:00:00

abstract：:In gouty patients, urate lowering therapies (ULTs) are recommended to bring serum uric acid (SUA) levels below 6.0 mg/dL, with the aim of dissolving urate depositions, thereby reducing disease impact. However, patients with hyperuricemia often present with other conditions associated with cardiovascular (CV) risk, suc...

journal_title：Current medical research and opinion

authors： Johnson RJ

更新日期：2015-01-01 00:00:00

abstract：:Quetiapine fumarate is a novel dibenzothiazepine antipsychotic developed by Zeneca. It is marketed under the trade name 'Seroquel'. Quetiapine is well tolerated and clinically effective in the treatment of schizophrenia. The initial hope of investigators was that quetiapine would have antipsychotic potential and that ...

journal_title：Current medical research and opinion

authors： Green B

更新日期：1999-01-01 00:00:00

abstract：:A double-blind study was carried out to investigate the prophylactic use of single-dose cefuroxime in elective abdominal surgery. Twenty-three patients received 1.5 g cefuroxime by intravenous injection immediately prior to induction of anaesthesia; 24 patients received no antibiotics. In the cefuroxime group, there w...

journal_title：Current medical research and opinion

authors： Lambert WG,Mullinger BM

更新日期：1980-01-01 00:00:00

abstract：:Four hundred and twenty-seven hypertensive patients in the United Kingdom have so far been admitted to two on-going open multicentre trials, and have been treated with acebutolol for periods ranging from 1 to 6 months. Oral dosages were within the range of 100 mg to 1200 mg/day in divided doses and were increased or d...

journal_title：Current medical research and opinion

authors： Ashton WL

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to analyze the characteristics and costs of exogenous endoscopy-related infections, pseudo-infections, and toxic reactions in the US. METHODS:A systematic review of the scientific literature published between 1966 and 2005 was conducted in Medline. Data collection was based o...

journal_title：Current medical research and opinion

authors： Seoane-Vazquez E,Rodriguez-Monguio R,Visaria J,Carlson A

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:Corticotropin-releasing hormone (CRH) is one of the most potent vasodilatory factors in the human feto-placental circulation. The expression of CRH was significantly down-regulated in patients with intrahepatic cholestasis of pregnancy (ICP). METHODS:One hundred pregnant women diagnosed with ICP at 34-34(+6)...

journal_title：Current medical research and opinion

authors： Zhou F,Zhang L,He MM,Liu ZF,Gao BX,Wang XD

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To systematically identify and assess current quality measures for anticoagulation in atrial fibrillation (AF), venous thromboembolism (VTE) treatment and surgical VTE prophylaxis. RESEARCH DESIGN AND METHODS:Fifteen quality measure websites were searched as were bibliographic databases (January 2000-Februar...

journal_title：Current medical research and opinion

authors： Sobieraj DM,White CM,Parker M,Bookhart BK,Coleman CI

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:To estimate the proportion of patients with moderate to severe chronic kidney disease (CKD) whose initial dipeptidyl-peptidase-4 inhibitor (DPP4-i) dosage was concordant with prescribing information (label) recommendations in the United States. METHODS:Adult patients with type 2 diabetes mellitus (T2DM) who ...

journal_title：Current medical research and opinion

authors： Huang H,Shetty S,Bauer E,Lang K

更新日期：2018-06-01 00:00:00

abstract：:An open study was carried out in 41 children with mild to moderate psoriasis to assess the effectiveness and tolerance of treatment with a 0.1% dithranol plus 17% urea preparation applied twice daily. Thirty-four patients completed 6-weeks' treatment and 8 of them continued for a further 4 to 6 weeks. The results show...

journal_title：Current medical research and opinion

authors： Guerrier CJ,Porter DI

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:This study was designed to assess the safety of 25- and 50-mg dosage strengths of zonisamide for initial titration in patients with epilepsy. RESEARCH DESIGN AND METHODS:This phase 3, multicenter, open-label, uncontrolled study conducted at 26 study sites in the United States included male and female patient...

journal_title：Current medical research and opinion

authors： Uthman BM,Miller GS,Montouris G,James SP,Anthony S,Zonisamide 501 Study Group.

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To evaluate intraocular pressure (IOP)-lowering efficacy, tolerability, and safety of the fixed combination of bimatoprost 0.03% and timolol 0.5% (Ganfort) among German patients. METHODS:Multicenter, observational, open-label study of patients with primary open angle glaucoma or ocular hypertension (n = 606)...

journal_title：Current medical research and opinion

authors： Feuerhake C,Buchholz P,Kimmich F

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that first-line treatment with atomoxetine provides superior efficacy than placebo for up to 12 weeks in improving the symptoms of Attention Deficit/Hyperactivity Disorder (ADHD). RESEARCH DESIGN AND METHODS:This double-blind, randomized, placebo-controlled, parallel clinical trial inc...

journal_title：Current medical research and opinion

authors： Montoya A,Hervas A,Cardo E,Artigas J,Mardomingo MJ,Alda JA,Gastaminza X,García-Polavieja MJ,Gilaberte I,Escobar R

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:The best management of patients with femoropopliteal and infrapopliteal artery occlusion disease is not clear. This study aimed to compare the efficacy of drug-coated balloons (DCBs) and drug-eluting stents (DESs) with percutaneous transluminal angioplasty (PTA) in patients with femoropopliteal or infrapoplit...

journal_title：Current medical research and opinion

authors： Chen X,Li J,Zheng C,He Y,Jia J,Wang X,Li D,Shang T,Li M

更新日期：2018-01-01 00:00:00

abstract：:All the components of the kallikrein-kinin system are located in the vascular smooth muscle as well as in the heart. In recent years, numerous observations obtained from clinical and experimental models of diabetes, hypertension, cardiac failure, ischaemia, myocardial infarction and left ventricular hypertrophy, have ...

journal_title：Current medical research and opinion

authors： Sharma JN,Sharma J

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To investigate the associations between obesity and any significant improvements in glycemic control, blood pressure, and lipid targets in Chinese patients with concomitant type 2 diabetes mellitus (T2DM) and hypertension. METHODS AND RESULTS:A total of 3041 dyslipidemia patients with an average age of 65.7 ...

journal_title：Current medical research and opinion

authors： Li P,Chen K,Nie Y,Guo LL,Wang HB,Wang SS,Wang AP,Hu DY,Mu YM,Li JH,DYSIS-China Study Investigators.

更新日期：2015-01-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia seen in clinical practice and has attracted much attention due to its association with a substantial mortality and morbidity, particularly from stroke, thromboembolism and heart failure. This Editorial Commentary provides a brief overview of the ...

journal_title：Current medical research and opinion

authors： Khoo CW,Lip GY

更新日期：2009-05-01 00:00:00

abstract：:A study was carried out to compare a new, unique chemical strip test for the measurement of urine specific gravity with the traditional methods of hydrometry and refractometry, during water concentration/dilution tests in 12 normal subjects. The pattern of specific gravity results during these serial measurements was ...

journal_title：Current medical research and opinion

authors： Gounden D,Newall RG

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:For the prevention of chemotherapy-induced febrile aplasia, a single injection of pegfilgrastim per cycle has the same efficacy as six to ten injections of conventional granulocyte colony-stimulating factor (G-CSF). However, there are few data on the economic impact of pegfilgrastim use, especially in the co...

journal_title：Current medical research and opinion

authors： Tan Sean P,Chouaid C,Hettler D,Baud M,Hejblum G,Tilleul P

更新日期：2009-06-01 00:00:00

abstract：:A single-blind, open-label controlled study was carried out in 30 healthy male volunteers to compare gastro-intestinal blood loss before, during and after treatment with a new, sustained-release formulation of the non-steroidal anti-inflammatory agent etodolac (etodolac SR) or with naproxen. Subjects remained at the s...

journal_title：Current medical research and opinion

authors： Leese P

更新日期：1992-01-01 00:00:00