A controlled study of benzydamine oral rinse ("Difflam") in general practice.

abstract：OBJECTIVE:This observational study was conducted to document the safety of capecitabine-based adjuvant therapy in patients with resected colon cancer under routine clinical conditions. RESEARCH AND DESIGN METHODS:ML20431 was a prospective, multicenter, non-interventional, observational study. It was designed to answer...

journal_title：Current medical research and opinion

authors： Steffens CC,Tschechne B,Schardt C,Jacobs G,Valdix AR,Schmidt P,Hansen R,Kröning H,Wohlfarth T,Guggenberger D

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To compare acute normovolemic hemodilution versus low central venous pressure strategy versus conventional fluid management in reducing intraoperative estimated blood loss, hematocrit drop and need for blood transfusion in patients undergoing radical retropubic prostatectomy under general anesthesia. RESEARC...

journal_title：Current medical research and opinion

authors： Habib AS,Moul JW,Polascik TJ,Robertson CN,Roche AM,White WD,Hill SE,Nosnick I,Gan TJ,Duke Perioperative Outcome Study Group.

更新日期：2014-05-01 00:00:00

abstract：UNLABELLED:Abstract Background: The Schizophrenia Trial of Aripiprazole (STAR) showed superior efficacy for aripiprazole compared with atypical antipsychotic standard-of-care (SOC) for the community treatment of schizophrenia 1 based on the Investigator Assessment Questionnaire total score. OBJECTIVE:To determine the ...

journal_title：Current medical research and opinion

authors： King D,Knapp M,Thomas P,Razzouk D,Loze JY,Kan HJ,van Baardewijk M

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Delayed-release dimethyl fumarate (DMF; also known as gastro-resistant DMF) and fingolimod are approved oral disease-modifying treatments for relapsing-remitting multiple sclerosis. In phase 3 trials, DMF (DEFINE/CONFIRM) and fingolimod (FREEDOMS/FREEDOMS II) resulted in significant reductions in clinical and...

journal_title：Current medical research and opinion

authors： Fox RJ,Chan A,Zhang A,Xiao J,Levison D,Lewin JB,Edwards MR,Marantz JL

更新日期：2017-02-01 00:00:00

abstract：:One hundred and eight patients who had been taking phenytoin for a year or more, either alone or in combination with other drugs, were examined for gum hypertrophy by three observers independently. Approximately 90% of the patients showed either mild or no gum hypertrophy and severe swelling occurred in only 1%. The o...

journal_title：Current medical research and opinion

authors： Grant RH,Parsonage MJ,Barot MH

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To compare the analgesic efficacy and safety of oxymorphone extended release (ER) and oxycodone controlled release (CR) in patients with moderate to severe cancer pain. RESEARCH DESIGN AND METHODS:This randomized, multicenter, double-blind, 2-period crossover study included adult outpatients (>or= 18 years o...

journal_title：Current medical research and opinion

authors： Gabrail NY,Dvergsten C,Ahdieh H

更新日期：2004-06-01 00:00:00

abstract：:Oxaprozin (4,5-diphenyl-2-oxazolepropionic acid) is a non-steroidal anti-inflammatory drug (NSAID) which is effective in models of inflammation, pain and pyrexia. It is effective and well tolerated in the clinical management of adult rheumatoid arthritis (RA), osteoarthritis (OA), ankylosing spondylitis, soft tissue d...

journal_title：Current medical research and opinion

authors： Kean WF

更新日期：2004-08-01 00:00:00

abstract：:A long-term follow-up study was carried out in 44 Type II diabetic patients to confirm the lack of effect of gliclazide on body weight as well as its hypoglycaemic efficacy and tolerance. Patients were assessed for up to 51 months. The results showed no overall significant change in body weight, 21 patients gaining we...

journal_title：Current medical research and opinion

authors： Robb GH,Lowe SM

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to examine how lifestyle behaviors in the context of physical activity levels and screen time are associated with school absenteeism. METHODS:We analyzed 2005-2008 NHANES data of proxy interviews for 1048 children aged 6-11 years and in-person self-reports of 1117 adolescents ag...

journal_title：Current medical research and opinion

authors： Hansen AR,Pritchard T,Melnic I,Zhang J

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of selective laser trabeculoplasty (SLT) on the intraocular pressure (IOP) of untreated fellow eyes in patients with open-angle glaucoma. STUDY DESIGN:Retrospective chart review. PATIENTS AND METHODS:Charts of all patients who underwent SLT at the University of Texas Southwestern M...

journal_title：Current medical research and opinion

authors： Rhodes KM,Weinstein R,Saltzmann RM,Aggarwal N,Kooner KS,Petroll WM,Whitson JT

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Fasting during the month of Ramadan is practiced by over 1.5 billion Muslims worldwide. It remains unclear, however, how this change in lifestyle affects heart failure, a condition that has reached epidemic dimensions. This study examined the effects of fasting in patients with acute heart failure (AHF) usin...

journal_title：Current medical research and opinion

authors： Salam AM,Sulaiman K,Alsheikh-Ali AA,Singh R,Asaad N,Al-Qahtani A,Salim I,AlHabib KF,Al-Zakwani I,Al-Jarallah M,AlMahmeed W,Bulbanat B,Ridha M,Bazargani N,Amin H,Al-Motarreb A,Al Faleh H,Albackr H,Panduranga P,Shehab

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Migraine is frequently under-treated. The 4-item Migraine Assessment of Current Therapy (Migraine-ACT) questionnaire is a simple, patient-friendly tool to identify patients requiring change in acute migraine treatment. OBJECTIVE:To establish a predictive model for the Migraine-ACT questionnaire in primary c...

journal_title：Current medical research and opinion

authors： Pascual J,Láinez MJ,Baos V,García ML,López-Gil A

更新日期：2007-12-01 00:00:00

abstract：:Control of hypertension is hindered by the incidence of adverse events associated with therapy, which can result in low patient compliance. Specific angiotensin II receptor subtype AT1 blockers offer an alternative to the angiotensin converting enzyme inhibitors in the treatment of hypertension, as the incidence of si...

journal_title：Current medical research and opinion

authors： Levine B

更新日期：2001-01-01 00:00:00

abstract：:A study was carried out to determine the efficacy and long-term safety of dantrolene in treating stroke patients with spasticity limiting rehabilitation. Fifteen of the 18 patients studied experienced reduction in spasticity and clinical improvement after treatment with dantrolene sodium for 6 weeks. Fourteen of these...

journal_title：Current medical research and opinion

authors： Ketel WB,Kolb ME

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to quantify the incidence of thromboembolic events (specifically, deep vein thromboses [DVT] and pulmonary embolism [PE]) in patients with cancer, and to examine the effects of a major clinical trial design and execution factors on those incidence rates. RESEARCH DESIGN AND ME...

journal_title：Current medical research and opinion

authors： Reynolds MW,Shibata A,Zhao S,Jones N,Fahrbach K,Goodnough LT

更新日期：2008-02-01 00:00:00

abstract：:Evidence is needed to guide therapeutic decisions on patients who had ischaemic cerebral events. The recently published European/Australasian Stroke Prevention in Reversible Ischaemia Trial (ESPRIT), an open-label randomised controlled study, compared long-term treatment of patients randomised to aspirin 30-325 mg dai...

journal_title：Current medical research and opinion

authors： Einhäupl K

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the safety and clinical efficacy of alcaftadine 0.25% ophthalmic solution, a new topical anti-allergic agent for the prevention of the signs and symptoms of allergic conjunctivitis induced by conjunctival allergen challenge (CAC). STUDY DESIGN AND METHODS:This two-ar...

journal_title：Current medical research and opinion

authors： Torkildsen G,Shedden A

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:This trial evaluated the efficacy and safety of pregabalin dosed twice daily (BID) for relief of neuro-pathic pain associated with postherpetic neuralgia (PHN). RESEARCH DESIGN AND METHODS:The 13-week, double-blind, placebo-controlled study randomized 370 patients with PHN to pregabalin (150, 300, or 600 mg/...

journal_title：Current medical research and opinion

authors： van Seventer R,Feister HA,Young JP Jr,Stoker M,Versavel M,Rigaudy L

更新日期：2006-02-01 00:00:00

abstract：:An acute and chronic dosing pharmacokinetic study of the calcium antagonist nitrendipine was carried out in 8 normotensive volunteers (mean age 80.1 +/- 3.4 years) to investigate if drug accumulation occurred in the elderly. Subjects received 10 mg nitrendipine once daily by mouth for 8 days. Plasma nitrendipine conce...

journal_title：Current medical research and opinion

authors： Crome P,Baksi A,Edwards J,Marley J

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:To evaluate posaconazole pharmacokinetics in subjects with different degrees of hepatic impairment compared with matched healthy subjects. RESEARCH DESIGN AND METHODS:A total of 37 subjects were enrolled in this open-label, single-dose, parallel-group study; 19 with hepatic impairment and 18 healthy subjects...

journal_title：Current medical research and opinion

authors： Moton A,Krishna G,Ma L,O'Mara E,Prasad P,McLeod J,Preston RA

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:As of 2012, nearly 10% of Americans had diabetes mellitus. People with diabetes are at approximately double the risk of premature death compared with those in the same age groups without the condition. While the prevalence of diabetes has risen across all racial/ethnic groups over the past 30 years, rates ar...

journal_title：Current medical research and opinion

authors： Ferdinand KC,Nasser SA

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:It has been acknowledged that patients who receive a beta-blocker or diuretic based regimen are at increased risk of developing new-onset diabetes. Recently, angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) have been shown to decrease patients' odds of developing new-o...

journal_title：Current medical research and opinion

authors： Kuti EL,Baker WL,White CM

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:To describe a post hoc analysis comparing the effect of a hyaluronic acid (HA)-trehalose solution to an established eyedrop solution containing HA alone using Ocular Surface Disease Index (OSDI) score <19 as a threshold for moderate to severe dry eye disease (DED). METHODS:A phase III, randomized, controlled...

journal_title：Current medical research and opinion

authors： Doan S,Bremond-Gignac D,Chiambaretta F

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of percutaneous polidocanol injection (PPI) in treatment of predominantly cystic thyroid nodules. MATERIALS AND METHODS:This prospective study included 111 patients with 122 benign predominantly cystic thyroid nodules inducing pressure symptoms or cosmetic problems. The no...

journal_title：Current medical research and opinion

authors： Gong X,Zhou Q,Chen S,Wang F,Wu W,Chen X

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:GOAL (Gauging Osteoarthritis [OA] with Limbrel*), an open-label, post-marketing study was performed to determine the overall efficacy and gastrointestinal (GI) tolerability of flavocoxid, a novel, plant-based, anti-inflammatory medication, in a 'real world' clinical practice setting. To this end, the study e...

journal_title：Current medical research and opinion

authors： Pillai L,Burnett BP,Levy RM,GOAL Study Cooperative Group.

更新日期：2010-05-01 00:00:00

abstract：:An open study was carried out in 40 elderly patients suffering from osteoarthrosis of the hip to assess the effectiveness of 200 mg flurbiprofen daily, fiven either in tablet or liquid suspension form, over a period of 4 weeks. Statistical evaluation of the results in the 19 patients admitted to analysis showed that f...

journal_title：Current medical research and opinion

authors： Innes EH

更新日期：1977-01-01 00:00:00

abstract：:The results of a series of studies on body fluid, electrolytes and diuretics are discussed. The findings to date indicate that the sex difference between mean potassium plasma levels in men and women is preserved into old age. Contrary to previous suggestions, there would appear to be no transient self-correcting hypo...

journal_title：Current medical research and opinion

authors： McCarthy ST

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:To explore relationships between beta-cell function and incident cardiovascular events, death, and medical costs among elderly individuals. RESEARCH DESIGN AND METHODS:In a prospective, population-based cohort of 4555 elderly individuals, we examined the effect of beta-cell function on incident cardiovascula...

journal_title：Current medical research and opinion

authors： Curtis LH,Hammill BG,Bethel MA,Anstrom KJ,Liao L,Gottdiener JS,Schulman KA

更新日期：2008-01-01 00:00:00

abstract：:The efficacy and safety of etodolac (Ultradol) and acetaminophen plus codeine [A + C (Tylenol #3)] in controlling post-surgical pain were compared in an open-label, randomized, parallel-group outpatient study. Patients who were voluntarily having a vasectomy performed for sterilization were assigned to receive either ...

journal_title：Current medical research and opinion

authors： Casey R,Zadra J,Khonsari H

更新日期：1997-01-01 00:00:00

abstract：:Background: To investigate the effects of 1-month treatment in addition to standard care with a food supplement containing both Curcuma longa and Boswellia serrata extracts on tendinopathy symptoms. Method: This open-label, non-controlled, post-observational study included 670 patients suffering from tendinopathy recr...

journal_title：Current medical research and opinion

authors： Henrotin Y,Dierckxsens Y,Delisse G,Seidel L,Albert A

更新日期：2020-12-21 00:00:00