Abstract:
:Background: To investigate the effects of 1-month treatment in addition to standard care with a food supplement containing both Curcuma longa and Boswellia serrata extracts on tendinopathy symptoms. Method: This open-label, non-controlled, post-observational study included 670 patients suffering from tendinopathy recruited at different sites by Belgian general practitioners. Patients received a medical prescription for 1-month treatment with two tablets twice a day of a pharmaceutical grade food supplement containing both C. longa and B. serrata extracts. Pain and functional limitation were evaluated using a visual analog scale at the inclusion and 1-month treatment later. Patient satisfaction, concomitant drugs intake and side effects were also recorded. Results: After 1-month treatment, pain and functional limitation were significantly improved whatever the cause of tendinopathy, its localization, and the duration of symptoms. The pain score decreased from 6.16 ± 1.53 to 2.98 ± 1.64 (p < .0001), yielding a drop of 51.6% and the functional limitation score fell after 1-month treatment from 5.96 ± 1.73 to 2.88 ± 1.67 (p < .0001) corresponding to a drop of 51.6%. The percentage of patients taking at least one concomitant treatment at the end of the treatment period had decreased from 81.3% to 61.8% (p < .0001). Only 43 (6.5%) patients reported side effects. No severe adverse effects related to the product were reported. Conclusion: The combination of C. longa and B. serrata extracts improves symptoms in patients suffering of tendinopathy and shows a good safety. Although its effect will have to be confirmed in randomized controlled trials, it can be considered as a helpful support of standard symptomatic treatments for tendinopathies. Highlights Tendinopathy is a common disease representing 30% of all consultations with a general practitioner for musculoskeletal disorders. The combination of Curcuminoids and Boswelliaserrata extracts are efficient on tendinopathy symptoms in support of standard symptomatic treatments. The combination of Curcuminoids and B. Serrata extract is safe and can be administrated for at least 1 month in addition of analgesic and non-steroidal anti-inflammatory drugs.
journal_name
Curr Med Res Opinjournal_title
Current medical research and opinionauthors
Henrotin Y,Dierckxsens Y,Delisse G,Seidel L,Albert Adoi
10.1080/03007995.2020.1860923subject
Has Abstractpub_date
2020-12-21 00:00:00pages
1-20eissn
0300-7995issn
1473-4877pub_type
杂志文章abstract:BACKGROUND:The fentanyl HCl iontophoretic transdermal system (ITS) is a patient-controlled analgesic delivery system that actively administers bolus doses of fentanyl transdermally upon patient activation. OBJECTIVE:To determine the amount of fentanyl absorbed from fentanyl ITS via passive absorption over a 24.5-h per...
journal_title:Current medical research and opinion
pub_type: 杂志文章
doi:10.1185/03007990802594941
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abstract:BACKGROUND:Adequate bowel preparation prior to colonic diagnostic procedures is essential to ensure adequate visualisation. SCOPE:This consensus aims to provide guidance as to the appropriate use of bowel preparation for a range of defined clinical circumstances. A consensus group from across Europe was convened and m...
journal_title:Current medical research and opinion
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abstract::Objective: To examine the potential sociodemographic disparities in type 2 diabetes (T2D) management and care among US adult individuals, after controlling for clinical and behavioral factors.Methods: This was a retrospective cohort study of individuals with T2D (N = 4552) from a linked database of the National Health...
journal_title:Current medical research and opinion
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journal_title:Current medical research and opinion
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1185/03007997509114793
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journal_title:Current medical research and opinion
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journal_title:Current medical research and opinion
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journal_title:Current medical research and opinion
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Current medical research and opinion
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Current medical research and opinion
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Current medical research and opinion
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Current medical research and opinion
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2020-12-09 00:00:00
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journal_title:Current medical research and opinion
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Current medical research and opinion
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pub_type: 共识发展会议,杂志文章,评审
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