Passive absorption of fentanyl from the fentanyl HCl iontophoretic transdermal system.

abstract：:Zolmitriptan has been developed in an orally disintegrating tablet (ODT) formulation that rapidly dissolves on the tongue and can be taken quickly, conveniently and discreetly without fluid intake. In this 3-month, non-comparative, observational, post-marketing surveillance (PMS) study, 5,570 physicians prescribed the...

journal_title：Current medical research and opinion

authors： Diener HC,Gendolla A

更新日期：2005-01-01 00:00:00

abstract：:Although the statistical strength of direct comparative randomized controlled trials is generally acknowledged, the particular demands of therapeutic decision making will often require indirect comparisons to be made, based on pooled data from multiple trials. As for all post-hoc analyses, the process of indirect comp...

journal_title：Current medical research and opinion

authors： Belsey JD

更新日期：2015-02-01 00:00:00

abstract：:Two hundred and two patients with symptoms, signs and mycological evidence of Candida vaginitis were entered in a single-blind trial comparing 6-day clotrimazole therapy with a control group receiving 6 days' nystatin therapy. Adequate data was collected on 69 clotrimazole and 72 nystatin treated patients for analysis...

journal_title：Current medical research and opinion

authors： Masterton G,Henderson J,Napier IR,Moffet M

更新日期：1975-01-01 00:00:00

abstract：:Liver transplantation is currently a standard therapy for patients with end-stage liver diseases and hepatocellular carcinoma. Given that liver transplantation has undergone a thriving development in these decades, the survival rates after liver transplantation have markedly improved as a result of the critical advanc...

journal_title：Current medical research and opinion

authors： Mu J,Chen Q,Zhu L,Wu Y,Liu S,Zhao Y,Ma T

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Reduction in total cholesterol (TC) and LDL-cholesterol (LDL-C) forms one of the principal objectives of most cardiovascular secondary prevention strategies. Many patients being treated with statins, however, have significant residual dyslipidaemia, with many having suboptimal HDL-cholesterol ...

journal_title：Current medical research and opinion

authors： Belsey J,de Lusignan S,van Vlymen J,Chan T,Hague N

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:The relationship between chronic pancreatitis (CP) and subsequent pyogenic liver abscess (PLA) is not well understood. METHODS:We investigated the risk of PLA in patients with CP using inpatient claims data from the Taiwan National Health Insurance Program for the period 2000-2010. We identified 17,810 pati...

journal_title：Current medical research and opinion

authors： Tseng CW,Chen YT,Lin CL,Liang JA

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To compare acute normovolemic hemodilution versus low central venous pressure strategy versus conventional fluid management in reducing intraoperative estimated blood loss, hematocrit drop and need for blood transfusion in patients undergoing radical retropubic prostatectomy under general anesthesia. RESEARC...

journal_title：Current medical research and opinion

authors： Habib AS,Moul JW,Polascik TJ,Robertson CN,Roche AM,White WD,Hill SE,Nosnick I,Gan TJ,Duke Perioperative Outcome Study Group.

更新日期：2014-05-01 00:00:00

abstract：:This study evaluated the prognostic significance of several risk factors on the outcome of coronary heart disease (CHD) in 639 cardiovascular disease-free subjects with heterozygous familial hypercholesterolaemia (FH). During the 15-year follow-up, 53 (18%) men and 34 (9.8%) women had a CHD event (men vs women, p < 0....

journal_title：Current medical research and opinion

authors： Panagiotakos DB,Pitsavos C,Skoumas J,Chrysohoou C,Toutouza M,Stefanadis CI,Toutouzas PK

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Tobacco smoking is a major risk factor for cardiovascular disease, respiratory disease and cancer and, for current smokers, smoking cessation is one of the most effective therapeutic interventions for reducing the risk of all-cause morbidity and mortality. However, smoking cessation causes nicotine withdrawa...

journal_title：Current medical research and opinion

authors： Aubin HJ

更新日期：2009-02-01 00:00:00

abstract：:Two hundred and sixty male patients with gonorrhoea, allocated to 4 unequal groups, were treated with one single oral dose of: (a) 2 g epicillin plus 1 g probenecid, (b) 2 g epicillin alone, (c) 1 g epicillin, 1 g cephradine plus 1 g probenecid, and (d) 1 g epicillin and 1 g cephradine. The last 3 groups acted as cont...

journal_title：Current medical research and opinion

authors： Theodoridis A,Marcollou-Kindi O,Vagana A,Sivenas C,Capetanakis J

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:To evaluate posaconazole pharmacokinetics in subjects with different degrees of hepatic impairment compared with matched healthy subjects. RESEARCH DESIGN AND METHODS:A total of 37 subjects were enrolled in this open-label, single-dose, parallel-group study; 19 with hepatic impairment and 18 healthy subjects...

journal_title：Current medical research and opinion

authors： Moton A,Krishna G,Ma L,O'Mara E,Prasad P,McLeod J,Preston RA

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:To compare 1-year direct healthcare costs and utilization among children and adolescents initiating non-stimulant medications atomoxetine (ATX) or extended-release guanfacine (GXR). METHODS:In this retrospective, observational cohort study, children and adolescents aged 6-17 years with attention deficit/hyp...

journal_title：Current medical research and opinion

authors： Molife C,Haynes VS,Nyhuis A,Faries DE,Gelwicks S,Kelsey DK,Alatorre CI

更新日期：2018-04-01 00:00:00

abstract：:An open study was carried out in 37 patients, with chronic, moderate to severe gastric or bilious reflux associated with hiatus hernia or subsequent to gastro-oesophageal surgery, to assess the effectiveness of an alginate/antacid combination product ('Gastrocote'). The overall success rate of treatment was 81% after ...

journal_title：Current medical research and opinion

authors： Hasan SS

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:This study evaluated the long-term cost-effectiveness of atorvastatin 20 mg, rosuvastatin 10 mg and simvastatin 40 mg in primary and secondary prevention of CHD in Finland. RESEARCH DESIGN AND METHODS:The effect of statin therapy on the incidence of CHD and the expected total costs of the disease were descri...

journal_title：Current medical research and opinion

authors： Peura P,Martikainen J,Soini E,Hallinen T,Niskanen L

更新日期：2008-06-01 00:00:00

abstract：:A double-blind trial was carried out in 76 patients with active rheumatoid arthritis to compare the analgesic and anti-inflammatory activity of 3 g. alclofenac with 4.8 g. aspirin daily over a 6-week period. All patients selected showed reversible inflammatory swelling of the finger joints. Of the 60 patients successf...

journal_title：Current medical research and opinion

authors： Bedi SS

更新日期：1975-01-01 00:00:00

abstract：:The sensitivity of a number of beta-lactamase producing strains of Enterobacter aerogenes, Enterobacter cloacae, Enterobacter species, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Proteus mirabilis, Proteus vulgaris, Pseudomonas aeruginosa and Serratia marcescens to cefamandole, cefoxitin, cefuroxi...

journal_title：Current medical research and opinion

authors： Kuipers JS

更新日期：1981-01-01 00:00:00

abstract：:A study was carried out to compare a new, unique chemical strip test for the measurement of urine specific gravity with the traditional methods of hydrometry and refractometry, during water concentration/dilution tests in 12 normal subjects. The pattern of specific gravity results during these serial measurements was ...

journal_title：Current medical research and opinion

authors： Gounden D,Newall RG

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Untreated and under-treated pain represent one of the most pervasive health problems, which is worsening as the population ages and accrues risk for pain. Multiple treatment options are available, most of which have one mechanism of action, and cannot be prescribed at unlimited doses due to the ceiling of ef...

journal_title：Current medical research and opinion

authors： Varrassi G,Hanna M,Macheras G,Montero A,Montes Perez A,Meissner W,Perrot S,Scarpignato C

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:The injection force and the patient perception of the Next Generation FlexPen (NGFP) with design modifications aimed at reducing injection force was assessed. The accuracy and precision of the NGFP was also tested under standard conditions. RESEARCH DESIGN AND METHODS:Dosing accuracy was tested (according to...

journal_title：Current medical research and opinion

authors： Pfützner A,Reimer T,Hohberg C,Frøkjaer LP,Jørgensen C

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Patients with hypereosinophilic syndrome (HES) vary considerably in their clinical presentation with regard to the severity and pattern of end-organ involvement. Clinical manifestations range from nonspecific symptoms to life-threatening, multisystem damage caused by eosinophil infiltration and local release...

journal_title：Current medical research and opinion

authors： Schwartz LB,Sheikh J,Singh A

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Most patients with hypertension require more than one drug to attain recommended blood pressure (BP) targets. Initiating therapy with two agents is recommended for patients at high risk of a cardiovascular event or with a BP > 20/10 mmHg above goal. Combination therapy is effective when comprised of agents w...

journal_title：Current medical research and opinion

authors： Ram CV

更新日期：2009-01-01 00:00:00

abstract：AIMS:The safety and efficacy of exenatide BID (exenatide) and insulin glargine (glargine) have been studied in clinical trials with few elderly patients. This study examined the clinical effectiveness of exenatide compared to glargine in patients 65 years and older with type 2 diabetes mellitus (T2DM). METHODS:A retro...

journal_title：Current medical research and opinion

authors： Pawaskar M,Li Q,Reynolds MW

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:The presence of midline shift on neuroradiologic studies in brain tumor patients represents mass effect from the tumor and surrounding edema. We hypothesized that baseline cerebral edema as measured by midline shift would increase postoperative nausea (PON). We studied the incidence of PON in brain tumor pat...

journal_title：Current medical research and opinion

authors： Ouyang MW,McDonagh DL,Phillips-Bute B,James ML,Friedman AH,Gan TJ

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Modern immunology has been extremely successful in elucidating many features of the immune system, but not in stemming pandemics of non-infectious, immune-related disease associated with industrialized populations. These pandemics involve a broad range of allergic, autoimmune, and inflammatory diseases, poten...

journal_title：Current medical research and opinion

authors： Parker W,Perkins SE,Harker M,Muehlenbein MP

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Migraine is frequently under-treated. The 4-item Migraine Assessment of Current Therapy (Migraine-ACT) questionnaire is a simple, patient-friendly tool to identify patients requiring change in acute migraine treatment. OBJECTIVE:To establish a predictive model for the Migraine-ACT questionnaire in primary c...

journal_title：Current medical research and opinion

authors： Pascual J,Láinez MJ,Baos V,García ML,López-Gil A

更新日期：2007-12-01 00:00:00

abstract：:A study was carried out in 21 patients with Type IIb or Type IV hyperlipoproteinaemia to evaluate the effect of treatment with 600 mg bezafibrate per day over a period of 3 months. The results of the lipid parameters studied showed that there were significant reductions after 1 and 3-months' treatment, respectively, o...

journal_title：Current medical research and opinion

authors： Neuman MP,Kurlat MI,Neuman J

更新日期：1983-01-01 00:00:00

abstract：:Filgrastim prophylaxis, both primary and secondary, was rapidly incorporated into clinical practice in the 1990s. When pegfilgrastim became available in 2002, it quickly replaced filgrastim as the colony-stimulating factor (CSF) of choice for prophylaxis. Use of prophylaxis increased markedly in the first decade of th...

journal_title：Current medical research and opinion

authors： Edelsberg J,Weycker D,Bensink M,Bowers C,Lyman GH

更新日期：2020-03-01 00:00:00

abstract：:A multi-centre, double-blind trial was carried out in general practice in 44 patients with symptoms of neurotic anxiety to compare the effects of treatment with either 400 mg chlormezanone at night or 5 mg diazepam 3-times daily for 4 weeks. The results indicated tht there were similar improvements in anxiety, duratio...

journal_title：Current medical research and opinion

authors： Allin DM

更新日期：1982-01-01 00:00:00

abstract：:The results of recent clinical trials with rivastigmine show that in the approved indication of mild to moderate Alzheimer's disease (AD), the drug is effective in the long term. Rivastigmine produces a significant delay in the decline of the three components of AD that have been identified by European guidelines as e...

journal_title：Current medical research and opinion

authors： Gabelli C

更新日期：2003-01-01 00:00:00

abstract：:An open, multi-centre, non-comparative study was carried out in general practice to assess the efficacy and tolerance of piroxicam in 159 patients with osteoarthritis and 27 patients with rheumatoid arthritis. Initial dosage ranged from 10 to 40 mg piroxicam and all but a few patients continued treatment with 20 mg on...

journal_title：Current medical research and opinion

authors： Gow PJ

更新日期：1983-01-01 00:00:00