Abstract:
BACKGROUND:The relationship between chronic pancreatitis (CP) and subsequent pyogenic liver abscess (PLA) is not well understood. METHODS:We investigated the risk of PLA in patients with CP using inpatient claims data from the Taiwan National Health Insurance Program for the period 2000-2010. We identified 17,810 patients with chronic pancreatitis (CP group) and 71,240 patients without CP (non-CP group). Both cohorts were followed until a diagnosis of PLA, until they were censored from the study because of loss to follow-up, death, or termination of insurance, or until the study cut-off date of 31 December 2011. Incidence and risk factors for development of PLA, and the effects of comorbidities, were assessed. RESULTS:The incidence of PLA in the CP group was 12.9 times that in the non-CP group (38.3 vs. 2.89 events per 1000 person-years; 95% confidence interval [CI], 10.5-15.8). After adjusting for age, sex, and the comorbidities of hypertension, diabetes, hyperlipidemia, cerebral vascular accident, cirrhosis, heart failure, chronic obstructive pulmonary disease, chronic kidney disease, cancer, alcoholism, other diseases of the pancreas, cholecystitis, and cholelithiasis and other disorders of the biliary tract and endoscopic insertion of stent (tube) into the bile duct, the risk of PLA remained higher among CP patients than among the comparison cohort (adjusted hazard ratio, 6.40; 95% CI, 4.83-8.49). CP patients with five or more comorbidities had a significantly higher risk of PLA (adjusted hazard ratio, 24.9; 95% CI, 18.3-33.8). CONCLUSION:CP was associated with increased risk of subsequent PLA. The risk of PLA was higher in patients with five or more comorbidities.
journal_name
Curr Med Res Opinjournal_title
Current medical research and opinionauthors
Tseng CW,Chen YT,Lin CL,Liang JAdoi
10.1080/03007995.2016.1266312subject
Has Abstractpub_date
2017-03-01 00:00:00pages
505-510issue
3eissn
0300-7995issn
1473-4877journal_volume
33pub_type
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journal_title:Current medical research and opinion
pub_type: 评论,杂志文章
doi:10.1185/03007995.2013.798637
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journal_title:Current medical research and opinion
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journal_title:Current medical research and opinion
pub_type: 杂志文章
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journal_title:Current medical research and opinion
pub_type: 杂志文章,随机对照试验
doi:10.1185/03007995.2010.532201
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journal_title:Current medical research and opinion
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journal_title:Current medical research and opinion
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journal_title:Current medical research and opinion
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journal_title:Current medical research and opinion
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1185/030079902125004312
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journal_title:Current medical research and opinion
pub_type: 临床试验,杂志文章
doi:10.1185/03007998609110447
更新日期:1986-01-01 00:00:00
abstract::The bioavailability of ofloxacin after a single dose of one of two tablet formulations (200 or 400 mg) or a liquid formulation (1.67 mg/ml) was investigated in 24 healthy male volunteers in an open randomized, crossover design study with a 5-day wash-out period between doses. Plasma concentrations of ofloxacin were de...
journal_title:Current medical research and opinion
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1185/03007999109112662
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Aripiprazole differs from other atypical antipsychotics in its pharmacological and clinical profile. SCOPE:As aripiprazole has been available in the USA for bipolar mania since 2004, clinical experience-sharing from clinical and research use of this agent can assist with initiation and administration in pra...
journal_title:Current medical research and opinion
pub_type: 杂志文章
doi:10.1185/03007990802341426
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journal_title:Current medical research and opinion
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doi:10.1080/03007995.2017.1366302
更新日期:2018-01-01 00:00:00
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journal_title:Current medical research and opinion
pub_type: 信件
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journal_title:Current medical research and opinion
pub_type: 杂志文章,评审
doi:10.1185/03007990802498440
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journal_title:Current medical research and opinion
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1185/03007998009109494
更新日期:1980-01-01 00:00:00
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journal_title:Current medical research and opinion
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Current medical research and opinion
pub_type: 杂志文章,meta分析,评审
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journal_title:Current medical research and opinion
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Current medical research and opinion
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journal_title:Current medical research and opinion
pub_type: 杂志文章
doi:10.1185/030079908x280455
更新日期:2008-04-01 00:00:00
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journal_title:Current medical research and opinion
pub_type: 杂志文章,meta分析
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更新日期:2007-06-01 00:00:00
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journal_title:Current medical research and opinion
pub_type: 杂志文章,评审
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更新日期:2019-04-01 00:00:00
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journal_title:Current medical research and opinion
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2009-04-01 00:00:00
abstract::Quetiapine fumarate is a novel dibenzothiazepine antipsychotic developed by Zeneca. It is marketed under the trade name 'Seroquel'. Quetiapine is well tolerated and clinically effective in the treatment of schizophrenia. The initial hope of investigators was that quetiapine would have antipsychotic potential and that ...
journal_title:Current medical research and opinion
pub_type: 杂志文章,评审
doi:10.1185/03007999909114085
更新日期:1999-01-01 00:00:00
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journal_title:Current medical research and opinion
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doi:10.1185/03007995.2015.1058249
更新日期:2015-08-01 00:00:00