A multi-centre study of piroxicam in the treatment of osteoarthritis and rheumatoid arthritis in general practice.

abstract：:The potential advantages of eletriptan lie firstly in its lipophilicity reflected as an increased rate of absorption and Tmax compared to sumatriptan. This is manifested in a modest advantage over sumatriptan in terms of speed of onset, 2 h headache response and 2 h pain free. However, eletriptan has not yet been show...

journal_title：Current medical research and opinion

authors： Giffin N

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:Most patients with hypertension require antihypertensive combination therapy to achieve BP control. This study investigated the safety and efficacy of the direct renin inhibitor aliskiren combined with the calcium channel blocker amlodipine. METHODS:Overall, 556 patients with hypertension (msDBP > or =95-<11...

journal_title：Current medical research and opinion

authors： Littlejohn TW 3rd,Trenkwalder P,Hollanders G,Zhao Y,Liao W

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To assess the impact of the decision by Kela (The Social Insurance Institution) to adopt guidelines for the management of food allergies in children, developed by the Finnish Medical Society Duodecim, as the basis for reimbursing clinical nutrition preparations for the treatment of cow milk allergy (CMA) in F...

journal_title：Current medical research and opinion

authors： Guest JF,Valovirta E

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:This study was undertaken to assess the long-term outcome of transcatheter arterial chemoembolization (TACE) after radiofrequency ablation (RFA) combined with a combined therapy for Chinese patients with intermediate (stage B) hepatocellular carcinoma (HCC) of single block type, and evaluate the survival rate...

journal_title：Current medical research and opinion

authors： Xu RC,Liu HC,Li JL,Li K,Ou SY,Yu ZY,Kong Y,Ma GA,Shao WS

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Migraine is frequently under-treated. The 4-item Migraine Assessment of Current Therapy (Migraine-ACT) questionnaire is a simple, patient-friendly tool to identify patients requiring change in acute migraine treatment. OBJECTIVE:To establish a predictive model for the Migraine-ACT questionnaire in primary c...

journal_title：Current medical research and opinion

authors： Pascual J,Láinez MJ,Baos V,García ML,López-Gil A

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To investigate the role of socio-economic factors on the therapeutic effectiveness of and therapeutic adherence to the angiotensin II receptor blocker (ARB) olmesartan (OM) alone or in combination with hydrochlorothiazide in the treatment of arterial hypertension. RESEARCH DESIGN AND METHODS:In a multi-cente...

journal_title：Current medical research and opinion

authors： Scholze J,Weinstock A,Kirchner F,Limberg R,Kreutz R

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:For the prevention of chemotherapy-induced febrile aplasia, a single injection of pegfilgrastim per cycle has the same efficacy as six to ten injections of conventional granulocyte colony-stimulating factor (G-CSF). However, there are few data on the economic impact of pegfilgrastim use, especially in the co...

journal_title：Current medical research and opinion

authors： Tan Sean P,Chouaid C,Hettler D,Baud M,Hejblum G,Tilleul P

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:The impact of multiple sclerosis (MS) center type on outcomes has not been investigated. This study aimed to evaluate baseline characteristics and clinical and magnetic resonance imaging (MRI) outcomes in patients with MS receiving fingolimod over 16 months' follow-up at private or academic centers in the USA...

journal_title：Current medical research and opinion

authors： Zivadinov R,Khan N,Korn JR,Lathi E,Silversteen J,Calkwood J,Kolodny S,Silva D,Medin J,Weinstock-Guttman B,MS-MRIUS study group.

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Low back pain in general and specifically chronic low back pain forms a major burden for the patient and society. Recently studies demonstrated that up to 65% of patients evolve to chronic pain as opposed to the previously accepted 8%. As low back pain patients present first with their general practitioner, ...

journal_title：Current medical research and opinion

authors： Itz C,Huygen F,Kleef MV

更新日期：2016-11-01 00:00:00

abstract：UNLABELLED:Abstract Background: The Schizophrenia Trial of Aripiprazole (STAR) showed superior efficacy for aripiprazole compared with atypical antipsychotic standard-of-care (SOC) for the community treatment of schizophrenia 1 based on the Investigator Assessment Questionnaire total score. OBJECTIVE:To determine the ...

journal_title：Current medical research and opinion

authors： King D,Knapp M,Thomas P,Razzouk D,Loze JY,Kan HJ,van Baardewijk M

更新日期：2011-02-01 00:00:00

abstract：:Objective: To evaluate the safety and efficacy of fulranumab as adjunct or monotherapy in patients with knee or hip pain related to moderate-to-severe osteoarthritis.Methods: Osteoarthritic patients (aged ≥18 years) from four phase 3 randomized, double-blind (DB), placebo-controlled studies were randomized to receive ...

journal_title：Current medical research and opinion

authors： Kelly KM,Sanga P,Zaki N,Wang S,Haeussler J,Louie J,Thipphawong J

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To examine the economic burden of myelodysplastic syndromes (MDS) and the incremental cost of transfusion dependence. RESEARCH DESIGN AND METHODS:Adults with evidence of MDS were identified between 05/01/2000 and 09/30/2003 from a longitudinal, retrospective claims database for a large, geographically divers...

journal_title：Current medical research and opinion

authors： Frytak JR,Henk HJ,De Castro CM,Halpern R,Nelson M

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:The literature on nonfulfillment of prescription medications spans over three decades of work. There is a wide variation in reported nonfulfillment rates, but no previous study has systematically reviewed this literature to explore the reasons behind this variation. OBJECTIVE:The objective of this study was...

journal_title：Current medical research and opinion

authors： Gadkari AS,McHorney CA

更新日期：2010-03-01 00:00:00

abstract：:Objectives: To evaluate central foveal thickness (CFT) variability and accompanying changes in visual acuity (VA) 12 months before and after treatment with the 190 mcg fluocinolone acetonide (FAc) intravitreal implant for diabetic macular edema (DME).Methods: The Iluvien Clinical Evidence cohort study in the United Ki...

journal_title：Current medical research and opinion

authors： Holden SE,Habib M,Currie CJ

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:The objectives of this article are to review the pathophysiology of type 2 diabetes mellitus (T2DM), present the rationale for a pathophysiologically based treatment approach for patients with T2DM and discuss the role of the therapeutic combination of pioglitazone and exenatide in the management of T2DM. ME...

journal_title：Current medical research and opinion

authors： Schwartz S

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:Clinical evidence supports the use of cardiac resynchronization therapy (CRT) in advanced heart failure, but its cost-effectiveness is still unclear. This analysis assessed the economic and health consequences in the UK of implanting a CRT in patients with NYHA class III-IV heart failure. METHODS:A discrete ...

journal_title：Current medical research and opinion

authors： Caro JJ,Guo S,Ward A,Chalil S,Malik F,Leyva F

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:In order to reduce individual cardiovascular risk, many patients require life-long lipid-lowering therapy, often as a drug combination approach. We aimed to describe the usage pattern, effectiveness and tolerability of long-term treatment with lipid-lowering agents, with particular focus on an oral combinati...

journal_title：Current medical research and opinion

authors： Hildemann SK,Barho C,Karmann B,Darius H,Bode C

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:Non-adherence to pain medication is common in chronic pain patients and may result in unfavorable treatment outcomes. Interventions to improve adherence behavior often fail to significantly change medication use. In this report, we describe the application of a theoretical psychological model of behavior chan...

journal_title：Current medical research and opinion

authors： Timmerman L,Stronks DL,Huygen FJPM

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:The prevalence of non-steroidal anti-inflammatory drug (NSAID) and concurrent gastroprotective agent (GPA) use in the US is not known. As such, the prevalence of GPA use among arthritis patients taking NSAIDs was examined. METHODS:Men and women aged ≥ 40 with self-reported arthritis and members of a web-base...

journal_title：Current medical research and opinion

authors： Coyne KS,Margolis MK,Cappelleri JC,Hsieh R,Essex MN,Park PW,Joshi AV

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:An economic analysis (based on interim data from a long-term, randomised, multi-centre, controlled, clinical trial) to evaluate chemotherapy with XELOX (capecitabine/oxaliplatin) versus FOLFOX6 (5Fluorouracil/leucovorin/oxaliplatin) as an adjuvant treatment for high risk colorectal cancer patients in Greece....

journal_title：Current medical research and opinion

authors： Maniadakis N,Fragoulakis V,Pectasides D,Fountzilas G

更新日期：2009-03-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia seen in clinical practice and has attracted much attention due to its association with a substantial mortality and morbidity, particularly from stroke, thromboembolism and heart failure. This Editorial Commentary provides a brief overview of the ...

journal_title：Current medical research and opinion

authors： Khoo CW,Lip GY

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To analyze the effect of brexpiprazole on metabolic parameters and body weight in adults with schizophrenia, including clinically relevant sub-groups of patients, based on data from two pivotal phase 3 studies (NCT01393613; NCT01396421) and a long-term extension study (NCT01397786). METHODS:The short-term st...

journal_title：Current medical research and opinion

authors： Newcomer JW,Eriksson H,Zhang P,Weiller E,Weiss C

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To describe the epidemiology and trends in pediatric gastrointestinal (GI) bleeding associated emergency department (ED) visits in the US. METHODS:Estimates of GI bleeding associated ED visits were calculated in children from birth to 19 years of age using the Nationwide Emergency Department Sample (NEDS). ...

journal_title：Current medical research and opinion

authors： Pant C,Olyaee M,Sferra TJ,Gilroy R,Almadhoun O,Deshpande A

更新日期：2015-02-01 00:00:00

abstract：:Women who are diagnosed with early breast cancer remain at considerable risk of recurrence over the next several decades, even if their tumors were small and lymph nodes were negative, and despite receiving standard adjuvant therapy. A majority of breast cancers are hormone (estrogen) receptor-positive and amenable to...

journal_title：Current medical research and opinion

authors： Chowdhury S,Ellis P

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:In a 4-week, double-blind, placebo-controlled study, the attention-promoting agent modafinil improved symptoms of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents and was well tolerated. To assess the continued efficacy of modafinil and obtain additional safety data, an 8-week, open...

journal_title：Current medical research and opinion

authors： Boellner SW,Earl CQ,Arora S

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Neurogenic bladder refers to morphofunctional alterations of the bladder-sphincter complex secondary to central or peripheral neurological lesions. Discal etiology can be suggested by clinical observation in patients complaining of classical lower back pain, but not excluded even without musculoskeletal pain....

journal_title：Current medical research and opinion

authors： Siracusa G,Sparacino A,Lentini VL

更新日期：2013-08-01 00:00:00

abstract：:Cholinesterase inhibitors, which act by inhibiting the degradation of acetylcholine in the brain, form the mainstay of therapy for AD. Predominant adverse events are cholinergic in nature, the most frequent being gastrointestinal side effects. Here we present a case series of patients with dementia who were treated wi...

journal_title：Current medical research and opinion

authors： Venkatesh K,Bullock R,Akbaş A

更新日期：2007-01-01 00:00:00

abstract：:Background: Actinic keratosis (AK) is considered an "in situ" non-melanoma skin cancer induced by ultraviolet chronic exposure. Sunscreen and topical anti-inflammatory agents like diclofenac could improve the evolution of this kind of lesions. A topical product containing piroxicam 0.8% and sun filters (50 SPF) (ACTX)...

journal_title：Current medical research and opinion

authors： Agozzino M,Russo T,Franceschini C,Mazzilli S,Garofalo V,Campione E,Bianchi L,Milani M,Argenziano G

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of fenofibrate and statin dual therapy versus a double or equivalent dose of statin monotherapy. METHODS:A systematic literature search and meta-analysis was performed for publications before 1 January 2014 in MEDLINE, Embase, and BIOSIS Previews, among others. RESULTS:The difference ...

journal_title：Current medical research and opinion

authors： Ouwens MJ,Nauta J,Ansquer JC,Driessen S

更新日期：2015-12-01 00:00:00

abstract：:For over a century, there has been considerable interest in the management of regional lymph node metastasis in patients with primary breast cancer. Since the advent of sentinel lymph node biopsies, there has been renewed interest in the management of patients with metastasis to the internal mammary nodes. The appropr...

journal_title：Current medical research and opinion

authors： Jatoi I

更新日期：2003-01-01 00:00:00