Burden of atrial fibrillation.

abstract：OBJECTIVE:To examine the economic burden of myelodysplastic syndromes (MDS) and the incremental cost of transfusion dependence. RESEARCH DESIGN AND METHODS:Adults with evidence of MDS were identified between 05/01/2000 and 09/30/2003 from a longitudinal, retrospective claims database for a large, geographically divers...

journal_title：Current medical research and opinion

authors： Frytak JR,Henk HJ,De Castro CM,Halpern R,Nelson M

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:Although a reduced aflibercept (2.0 mg) injection frequency relative to the approved dosing posology is included in national treatment guidelines for wet age-related macular degeneration (AMD), there is limited evidence of its comparative efficacy. The objective was to compare the efficacy and safety of reduc...

journal_title：Current medical research and opinion

authors： Szabo SM,Hedegaard M,Chan K,Thorlund K,Christensen R,Vorum H,Jansen JP

更新日期：2015-11-01 00:00:00

abstract：:Objectives: The purpose of this study was to assess (1) the trends of and (2) the factors associated with health information technology (HIT) use among older adults in the U.S.Methods: A decade (2009-2018) of data from the U.S. National Health Interview Survey (NHIS) was used. The trends of HIT use among older adults ...

journal_title：Current medical research and opinion

authors： Hung LY,Lyons JG,Wu CH

更新日期：2020-05-01 00:00:00

abstract：:The use of steroid compounds formulated in oil for depot injection can be associated with acute pulmonary reactions characterized primarily by cough, but sometimes with other associated symptoms. The pathophysiology of these reactions remains unclear, although they are reported in the literature as 'POMEs' or pulmonar...

journal_title：Current medical research and opinion

authors： Meyer RJ,Mann M

更新日期：2015-04-01 00:00:00

abstract：:Objective: A prior study found that hyaluronic acid (HA) treatment may help reduce pain medication use (such as steroids, non-steroidal anti-inflammatory drugs [NSAIDs] and opioids) among knee osteoarthritis (OA) patients in the real-world setting. This study aims to update the prior study results to include only the ...

journal_title：Current medical research and opinion

authors： Chitnis AS,Etter K,Holy CE,Gray FS,Manalac FJ,Bisson B,Bhattacharyya SK

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Adequate vitamin D and calcium nutrition play a critical role in the maintenance of musculoskeletal health and are considered the first step in osteoporosis treatment. ROUNDTABLE DISCUSSION:In February 2008 Merck Sharp & Dohme sponsored a 2-day, evidence-based expert panel on the benefits of vitamin D for t...

journal_title：Current medical research and opinion

authors： Roux C,Bischoff-Ferrari HA,Papapoulos SE,de Papp AE,West JA,Bouillon R

更新日期：2008-05-01 00:00:00

abstract：:Abstract A growing body of evidence suggests that targeting low-density lipoprotein cholesterol is not enough and that a substantial residual risk remains despite aggressive statin treatment, particularly in patients with mixed dyslipidemia. Statin plus fibrate combination results in a more effective control of severa...

journal_title：Current medical research and opinion

authors： Athyros VG,Tziomalos K,Karagiannis A,Mikhailidis DP

更新日期：2010-09-01 00:00:00

abstract：:Migraine is a very common disorder, affecting about 11% of adult populations in Western countries. Prevalence is highest during the peak productive years--between the ages of 25 and 55. The prevalence is higher in females than males at all post-pubertal ages, but the sex ratio varies with age. In the United States, mi...

journal_title：Current medical research and opinion

authors： Lipton RB,Stewart WF,Scher AI

更新日期：2001-01-01 00:00:00

abstract：:Objective: Health utility estimates for children and adolescents are critical for cost-utility analyses informing health technology assessment (HTA) authorities' decisions governing access to pediatric treatments. However, in a recent review, only 29% of published pediatric cost-utility models used a utility measure v...

journal_title：Current medical research and opinion

authors： Bégo-Le Bagousse G,Jia X,Wolowacz S,Eckert L,Tavi J,Hudson R

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:High-sensitivity C-reactive protein (hs-CRP) has been explored for use in predicting cardiovascular risk. The recent Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) study found that statin therapy reduced cardiovascular events in those with ...

journal_title：Current medical research and opinion

authors： Slejko JF,Page RL 2nd,Sullivan PW

更新日期：2010-10-01 00:00:00

abstract：:A double-blind, crossover trial was carried out in 40 in-patients with gastro-intestinal spasmodic syndromes to compare the effectiveness and tolerance of fenoverine and trimebutine. Patients were allocated at random to receive either 100 mg fenoverine or 150 mg trimebutine 3-times daily for 20 days and were then cros...

journal_title：Current medical research and opinion

authors： Camarri E

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:The validity of opinions expressed in questionnaire surveys diminishes with lower response rates. Recent research suggests that general practitioners (GPs) are more likely to respond to questionnaire surveys if they are motivated to do so because the subject of the survey is perceived as relevant to the prac...

journal_title：Current medical research and opinion

authors： Jiwa M,Coker AE,Bagley J,Freeman J,Coleman M

更新日期：2004-03-01 00:00:00

abstract：:As the emergence of cardiovascular disease (CVD) is linked to modifiable lifestyle and physiological factors, it is increasingly important to concentrate on preventative strategies. For preventative measures to be beneficial it is necessary to clearly identify patients at risk--given that multiple risk factors often c...

journal_title：Current medical research and opinion

authors： De Backer G

更新日期：2007-11-01 00:00:00

abstract：:Objective: Hypertension is a serious health problem in Egypt, with prevalence rate of 17% as reported in 2015. Despite receiving treatment, many do not achieve blood pressure (BP) control. The current study aimed to evaluate the efficacy and tolerability of amlodipine/valsartan/hydrochlorothiazide (Aml/Val/HCTZ) singl...

journal_title：Current medical research and opinion

authors： El-Etriby AMK,Rakha S

更新日期：2020-04-01 00:00:00

abstract：:The glomerular and tubular function of 7 patients with a spectrum of renal impairment was measured before, during and after 4-days' treatment with cefuroxime and gentamicin. Neither the mean plasma urea nor creatinine concentrations of the group increased after combined treatment, nor was the excretion of cefuroxime s...

journal_title：Current medical research and opinion

authors： Cockram CS,Richards P,Bax RP

更新日期：1980-01-01 00:00:00

abstract：:A study was carried out to compare the efficacy and tolerability of etodolac and piroxicam in patients with rheumatoid arthritis. Sixty patients entered this double-blind, parallel study and after a wash-out period of up to 2 weeks were randomly assigned to receive 200 mg etodolac twice daily or 20 mg piroxicam once d...

journal_title：Current medical research and opinion

authors： Schattenkirchner M

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Long-term oral corticosteroid (OCS) therapy and related adverse events are associated with a significant burden on patients and healthcare resources. METHODS:This subgroup analysis of a randomized, open-label, parallel-group study evaluated the OCS-sparing effect of omalizumab (OMA) added to optimized asthm...

journal_title：Current medical research and opinion

authors： Siergiejko Z,Świebocka E,Smith N,Peckitt C,Leo J,Peachey G,Maykut R

更新日期：2011-11-01 00:00:00

abstract：:All the components of the kallikrein-kinin system are located in the vascular smooth muscle as well as in the heart. In recent years, numerous observations obtained from clinical and experimental models of diabetes, hypertension, cardiac failure, ischaemia, myocardial infarction and left ventricular hypertrophy, have ...

journal_title：Current medical research and opinion

authors： Sharma JN,Sharma J

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Chronic obstructive pulmonary disease (COPD) is becoming a leading cause of morbidity and mortality in China. In the IMPACT trial, fluticasone furoate[FF]/umeclidinium[UMEC]/vilanterol[VI] single-inhaler triple therapy demonstrated lower rates of moderate/severe exacerbations than dual therapy with FF/VI or ...

journal_title：Current medical research and opinion

authors： Zheng J,Zhong N,Wang C,Wei LP,Zhou XD,Zhao L,Dong Yuan Y,He B,Wu B,Du X,Song J,Lipson DA

更新日期：2021-01-01 00:00:00

abstract：:In a multi-centre study, the antidepressant efficacy and incidence of on-therapy events of trazodone (100 to 400 mg daily) and mianserin (30 to 120 mg daily) was compared using a double-blind pre-determined randomized parallel group design in depressed patients unresponsive to placebo after a 7-day screening period. O...

journal_title：Current medical research and opinion

authors： Bennie EH,Khan MC,Tyrer SP,Siddiqui U,Ankier SI

更新日期：1984-01-01 00:00:00

abstract：:The therapeutic efficacy of cimetidine given as 400 mg twice daily was compared to that of cimetidine given as 1.0 g daily in 4 divided doses (200 mg 3-times daily and 400 mg at night) in two groups of 25 patients (total 50 patients) with active duodenal ulceration. After 4 weeks, healing rates of 72% and 76%, respect...

journal_title：Current medical research and opinion

authors： Papadopoulos C,Kalantzis N,Rekoumis G,Kanaghinis T

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Development of a second primary malignancy (SPM) after an index esophageal cancer is fairly rare, primarily due to decreased survival in patients with esophageal cancer. However, with advances in early detection and therapy, the number of long-term survivors is increasing, as is the incidence of SPMs in this...

journal_title：Current medical research and opinion

authors： Nandy N,Dasanu CA

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Delayed-release dimethyl fumarate (DMF; also known as gastro-resistant DMF) and fingolimod are approved oral disease-modifying treatments for relapsing-remitting multiple sclerosis. In phase 3 trials, DMF (DEFINE/CONFIRM) and fingolimod (FREEDOMS/FREEDOMS II) resulted in significant reductions in clinical and...

journal_title：Current medical research and opinion

authors： Fox RJ,Chan A,Zhang A,Xiao J,Levison D,Lewin JB,Edwards MR,Marantz JL

更新日期：2017-02-01 00:00:00

abstract：:Two clinical trials were carried out in order to study adrenal suppression in 6 patients with psoriatic erythroderma and in 28 patients with psoriasis treated with topical glucocorticosteroids. Betamethasone-17-valerate (0.1%), betamethasone-17,21-dipropionate (0.05%) and budesonide (0.025%) ointments were studied in ...

journal_title：Current medical research and opinion

authors： Salde L,Lassus A

更新日期：1983-01-01 00:00:00

abstract：:The therapeutic efficacy of 100 mg spironolactone once daily in patients with congestive heart failure was evaluated in a multi-centre study in general practice. One hundred and fifteen patients were admitted to the study. Clinical and haemotological assessments were made at entry and at regular intervals throughout t...

journal_title：Current medical research and opinion

authors： Smith AG

更新日期：1980-01-01 00:00:00

abstract：INTRODUCTION:Normoglycaemia in people with diabetes results in improved outcome. Continuous glucose monitoring provides detailed diagnostic information used to optimise therapy with the goal of achieving normoglycaemia. The objective of this study was to review the published literature evaluating the single device avai...

journal_title：Current medical research and opinion

authors： Currie CJ,Poole CD,Papo NL

更新日期：2009-10-01 00:00:00

abstract：:The term "mixed pain" is increasingly applied for specific clinical scenarios, such as low back pain, cancer pain and postsurgical pain, in which there "is a complex overlap of the different known pain types (nociceptive, neuropathic, nociplastic) in any combination, acting simultaneously and/or concurrently to cause ...

journal_title：Current medical research and opinion

authors： Freynhagen R,Rey R,Argoff C

更新日期：2020-12-01 00:00:00

abstract：:In a randomized trial, 149 patients with uncomplicated gonorrhoea were treated with a single intramuscular dose of 1.0 g mezlocillin, 150 with 2.0 g ampicillin plus 1.0 g probenecid orally and 150 with a single dose of 1.8 mega units of procaine penicillin. Cure rates at 3, 10 and 17 days after treatment were 97%, 99%...

journal_title：Current medical research and opinion

authors： Khan MH,Tomkyns JG

更新日期：1982-01-01 00:00:00

abstract：:This double-blind, randomised, placebo-controlled study was carried out to assess the efficacy and safety of 0.025% and 0.05% azelastine eye drops twice daily administered for 14 days to patients with seasonal allergic conjunctivitis or rhinoconjunctivitis. A total of 278 patients were recruited and 226 patients were ...

journal_title：Current medical research and opinion

authors： Lenhard G,Mivsek-Music E,Perrin-Fayolle M,Obtulowicz K,Secchi A

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:To compare the effectiveness of antiresorptive agents in reducing the risk of vertebral and non-vertebral fractures using data from published meta-analyses and the technique of adjusted indirect comparisons. RESEARCH DESIGN AND METHODS:Pairs of agents were compared by adjusted indirect comparison of 0.56 [0....

journal_title：Current medical research and opinion

authors： Wehren LE,Hosking D,Hochberg MC

更新日期：2004-04-01 00:00:00