Urine specific gravity measurements: comparison of a new reagent strip method with existing methodologies, as applied to the water concentration/dilution tests.

abstract：:A study was carried out in general practice to assess the clinical effectiveness and tolerability of the oral cephalosporin, cefuroxime axetil, in the treatment of 369 patients presenting with acute infections of the upper respiratory tract. The main diagnoses were tonsillitis, pharyngitis, sinusitis and otitis media....

journal_title：Current medical research and opinion

authors： Griffiths GK,VandenBurg MJ,Wight LJ,Gudgeon AC,Kelsey M

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:Most patients with hypertension require antihypertensive combination therapy to achieve BP control. This study investigated the safety and efficacy of the direct renin inhibitor aliskiren combined with the calcium channel blocker amlodipine. METHODS:Overall, 556 patients with hypertension (msDBP > or =95-<11...

journal_title：Current medical research and opinion

authors： Littlejohn TW 3rd,Trenkwalder P,Hollanders G,Zhao Y,Liao W

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Adherence to antihyperglycemic medication is thought to be suboptimal, but the proportion of patients missing doses, the number of doses missed, and reasons for missing are not well described. This survey was conducted to estimate the prevalence of and reasons for missed doses of oral antihyperglycemic medic...

journal_title：Current medical research and opinion

authors： Vietri JT,Wlodarczyk CS,Lorenzo R,Rajpathak S

更新日期：2016-09-01 00:00:00

abstract：:Abstract A growing body of evidence suggests that targeting low-density lipoprotein cholesterol is not enough and that a substantial residual risk remains despite aggressive statin treatment, particularly in patients with mixed dyslipidemia. Statin plus fibrate combination results in a more effective control of severa...

journal_title：Current medical research and opinion

authors： Athyros VG,Tziomalos K,Karagiannis A,Mikhailidis DP

更新日期：2010-09-01 00:00:00

abstract：:Although the statistical strength of direct comparative randomized controlled trials is generally acknowledged, the particular demands of therapeutic decision making will often require indirect comparisons to be made, based on pooled data from multiple trials. As for all post-hoc analyses, the process of indirect comp...

journal_title：Current medical research and opinion

authors： Belsey JD

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Rheumatoid arthritis (RA) is a chronic, debilitating disease affecting an estimated 1.5 million patients in the US. The condition is associated with a substantial health and economic burden. An economic model was developed to evaluate the cost-effectiveness of tofacitinib (a novel oral Janus k...

journal_title：Current medical research and opinion

authors： Claxton L,Taylor M,Gerber RA,Gruben D,Moynagh D,Singh A,Wallenstein GV

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To look into current evidence exploring the added value of rLH supplementation to rFSH in GnRH analogues cycles, to identify groups of women that still have no evidence for adjuvant rLH therapy and to discuss ways that may advance research on this topic. METHODS:Eight systematic reviews and meta-analyses exp...

journal_title：Current medical research and opinion

authors： Younis JS,Laufer N

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To analyze the construct validity of the EQ-5D in patients with acute coronary syndromes (ACS). METHODS:All ACS-diagnosed patients discharged from a university-affiliated hospital during a 3-year period were mailed a questionnaire that included the EQ-5D and the SF-8. The EQ-5D includes a visual analogue sca...

journal_title：Current medical research and opinion

authors： Ellis JJ,Eagle KA,Kline-Rogers EM,Erickson SR

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Over the last two decades the development and analysis of a number of registries have enhanced the knowledge of the epidemiology, presentation, natural history, and pathophysiology of pulmonary arterial hypertension (PAH). The understanding of the effectiveness of available treatments has also been greatly i...

journal_title：Current medical research and opinion

authors： Poscia R,Ghio S,D'Alto M,Vitulo P,Mulè M,Albera C,Parisi F,Badagliacca R,Fedele F,Vizza CD

更新日期：2014-12-01 00:00:00

abstract：:Objective: Global Phase III trials of suvorexant showed no obvious differences in the safety and efficacy profile of suvorexant between elderly and non-elderly patients. However, the clinical profile of suvorexant in elderly patients with comorbidities in a real-world setting was not evaluated. To further understand t...

journal_title：Current medical research and opinion

authors： Takeuchi Y,Sano H,Asai Y,Miyazaki M,Iwakura M,Maeda Y

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:To determine the extent to which raloxifene can maintain low density lipoprotein cholesterol (LDL-C) levels below 160 mg/dL or reduce elevated LDL-C levels to below lipid-lowering goals in postmenopausal women. PATIENTS AND METHODS:The Multiple Outcomes of Raloxifene Evaluation (MORE) osteoporosis treatment ...

journal_title：Current medical research and opinion

authors： Cox DA,Sarkar S,Harper K,Barrett-Connor E

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVES:Docetaxel and paclitaxel show significant clinical activity in metastatic breast cancer (MBC) and have been approved for MBC by the U.S. Food and Drug Administration, but it is still unclear whether a paclitaxel-based regimen improves outcomes over a docetaxel-based regimen in patients with MBC. We therefore...

journal_title：Current medical research and opinion

authors： Qi WX,Shen Z,Lin F,Sun YJ,Min DL,Tang LN,He AN,Yao Y

更新日期：2013-02-01 00:00:00

abstract：:The therapeutic efficacy of cimetidine given as 400 mg twice daily was compared to that of cimetidine given as 1.0 g daily in 4 divided doses (200 mg 3-times daily and 400 mg at night) in two groups of 25 patients (total 50 patients) with active duodenal ulceration. After 4 weeks, healing rates of 72% and 76%, respect...

journal_title：Current medical research and opinion

authors： Papadopoulos C,Kalantzis N,Rekoumis G,Kanaghinis T

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To examine outcomes associated with colesevelam treatment among patients with hypercholesterolemia in real-world clinical practice. METHODS:This analysis was conducted as a retrospective, observational cohort study in an ambulatory-care medical network in Northern California. Patients with orders for colesev...

journal_title：Current medical research and opinion

authors： Romanelli RJ,Leahy A,Jukes T,Ye X,Qian C,Ishisaka DY

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:Neurosurgery often requires skull immobilization with a Mayfield clamp, which often causes brief intense nociceptive stimulation, hypertension and tachycardia. Blunting this response may help prevent increased intracranial pressure, cerebral aneurysm or vascular malformation rupture, and/or myocardial stress....

journal_title：Current medical research and opinion

authors： Berger M,Philips-Bute B,Guercio J,Hopkins TJ,James ML,Borel CO,Warner DS,McDonagh DL

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:The pattern of renal transplantation has never been described since the introduction of the technique. The purpose of this study was therefore to characterise the pattern of renal transplantation from 1967 to 2000, focusing on renal graft function as a predictor of survival. METHODS:This study was a retrosp...

journal_title：Current medical research and opinion

authors： McEwan P,Baboolal K,Dixon S,Conway P,Currie CJ

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Fasting during the month of Ramadan is practiced by over 1.5 billion Muslims worldwide. It remains unclear, however, how this change in lifestyle affects heart failure, a condition that has reached epidemic dimensions. This study examined the effects of fasting in patients with acute heart failure (AHF) usin...

journal_title：Current medical research and opinion

authors： Salam AM,Sulaiman K,Alsheikh-Ali AA,Singh R,Asaad N,Al-Qahtani A,Salim I,AlHabib KF,Al-Zakwani I,Al-Jarallah M,AlMahmeed W,Bulbanat B,Ridha M,Bazargani N,Amin H,Al-Motarreb A,Al Faleh H,Albackr H,Panduranga P,Shehab

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To further assess the clinically active dose range of etoricoxib, a COX-2 selective inhibitor, in rheumatoid arthritis (RA). METHODS:RA patients were randomized to etoricoxib 10, 30, 60, or 90 mg or placebo in a double-blind, 12-week study. DMARDs (methotrexate, biologics) or low-dose corticosteroids were al...

journal_title：Current medical research and opinion

authors： Greenwald M,Peloso PM,Mandel D,Soto O,Mehta A,Frontera N,Boice JA,Zhan XJ,Curtis SP

更新日期：2011-10-01 00:00:00

abstract：:Objective To assess the efficacy of a mixed intervention, educational, and reminder calendar of the intake, as a strategy to improve therapeutic adherence with dabigatran in patients with non-valvular atrial fibrillation (NVAF). Methods This was a prospective, longitudinal, multi-center study, carried out in 110 speci...

journal_title：Current medical research and opinion

authors： Márquez-Contreras E,Martell-Claros N,Márquez-Rivero S,Hermida-Campa E,Gracia-Diez C,Sanchez-López E,Gil-Guillén V,Compliance and Inertia Working Group, Spanish Society of Hypertension (SEH-LELHA).

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Healthcare organizations must evaluate the cost effectiveness of the alternative therapies that are available to treat anemia and improve quality of life (QoL) of patients with cancer, that is, erythropoietic protein therapy and blood transfusion. METHODS:Pharmacoeconomic studies that evaluated the cost of ...

journal_title：Current medical research and opinion

authors： Cornes P,Coiffier B,Zambrowski JJ

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:The impact of multiple sclerosis (MS) center type on outcomes has not been investigated. This study aimed to evaluate baseline characteristics and clinical and magnetic resonance imaging (MRI) outcomes in patients with MS receiving fingolimod over 16 months' follow-up at private or academic centers in the USA...

journal_title：Current medical research and opinion

authors： Zivadinov R,Khan N,Korn JR,Lathi E,Silversteen J,Calkwood J,Kolodny S,Silva D,Medin J,Weinstock-Guttman B,MS-MRIUS study group.

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Small cell lung cancer (SCLC) patients, who have achieved complete or partial response after chemotherapy, should be followed with prophylactic cranial irradiation (PCI). PCI for extrapulmonary small cell carcinoma (EPSCC) is not routinely recommended. The purpose of this review is to discuss all aspects of ...

journal_title：Current medical research and opinion

authors： Yazıcı O,Ozdemir NY,Sendur MA,Aksoy S,Zengin N

更新日期：2014-07-01 00:00:00

abstract：:During the past decades several epidemiological studies have provided a 'portrait' of the potential candidate for cardiovascular disease, introducing many emerging life-style risk factors such as obesity, unhealthy diet, exposure to passive smoking, lack of exercise, psychosocial stress, and depression, as well as ele...

journal_title：Current medical research and opinion

authors： Pitsavos CE,Toutouzas PK

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:These studies evaluated the safety and efficacy of enteric-coated budesonide for the induction and maintenance of remission of mild-to-moderate Crohn's disease (CD) in children. METHODS:The consecutive, multicenter, open-label, non-comparative studies enrolled patients aged 6-17 years. In the induction study...

journal_title：Current medical research and opinion

authors： Cohen SA,Aloi M,Arumugam R,Baker R,Bax K,Kierkuś J,Koletzko S,Lionetti P,Persson T,Eklund S

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:Anemia is a complication of chronic kidney disease and may contribute to adverse clinical outcomes. Early identification and treatment of anemia may improve cardiovascular morbidity and mortality. No large-scale population data are available specifically for patients with chronic kidney disease regarding prev...

journal_title：Current medical research and opinion

authors： McClellan W,Aronoff SL,Bolton WK,Hood S,Lorber DL,Tang KL,Tse TF,Wasserman B,Leiserowitz M

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:Patients with type 2 diabetes (T2DM) often have multiple comorbidities which may impact the selection of antihyperglycemic therapies. The purpose of this study was to quantify the prevalence and co-prevalence of common comorbidities. RESEARCH DESIGN AND METHODS:A retrospective study was conducted using the Q...

journal_title：Current medical research and opinion

authors： Iglay K,Hannachi H,Joseph Howie P,Xu J,Li X,Engel SS,Moore LM,Rajpathak S

更新日期：2016-07-01 00:00:00

abstract：:Twenty-five acutely disturbed psychotic patients were treated in an open study with a single injection of zuclopenthixol acetate 5% in 'Viscoleo, a thin vegetable oil. Patients were assessed post-injection for 3 days using the BPRS, CGI, and a specially designed behaviour/activity scale. Doses of 50 to 150 mg proved e...

journal_title：Current medical research and opinion

authors： Chakravarti SK,Muthu A,Muthu PK,Naik P,Pinto RT

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:This trial evaluated the efficacy and safety of pregabalin dosed twice daily (BID) for relief of neuro-pathic pain associated with postherpetic neuralgia (PHN). RESEARCH DESIGN AND METHODS:The 13-week, double-blind, placebo-controlled study randomized 370 patients with PHN to pregabalin (150, 300, or 600 mg/...

journal_title：Current medical research and opinion

authors： van Seventer R,Feister HA,Young JP Jr,Stoker M,Versavel M,Rigaudy L

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVES:Epidemiological data support an association between age-related macular degeneration (AMD) and cataract surgery that may be attributed to post-operative blue light exposure. By limiting the retina's blue light exposure, new blue-light filtering intraocular lenses (BLF IOLs) have the potential to reduce the d...

journal_title：Current medical research and opinion

authors： Reddy P,Gao X,Barnes R,Fairchild C,Boci K,Waycaster C,Pashos C

更新日期：2006-07-01 00:00:00

abstract：:Quetiapine fumarate is a novel dibenzothiazepine antipsychotic developed by Zeneca. It is marketed under the trade name 'Seroquel'. Quetiapine is well tolerated and clinically effective in the treatment of schizophrenia. The initial hope of investigators was that quetiapine would have antipsychotic potential and that ...

journal_title：Current medical research and opinion

authors： Green B

更新日期：1999-01-01 00:00:00