Cardiovascular risk factor profile in Greece: results from the CARDIO2000 and ATTICA epidemiological studies.

abstract：OBJECTIVE:Painful physical symptoms are common in patients with major depressive disorder (MDD) and can negatively affect patient outcomes. Duloxetine has demonstrated efficacy in treating MDD and other certain painful conditions; this study specifically evaluated patients with both MDD and MDD-associated pain. METHOD...

journal_title：Current medical research and opinion

authors： Gaynor PJ,Gopal M,Zheng W,Martinez JM,Robinson MJ,Hann D,Marangell LB

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To develop a patient-completed screening tool to help differentiate nociceptive and neuropathic pain. RESEARCH DESIGN AND METHODS:A multicenter study was performed for item reduction (initial 89-item questionnaire) and model building. Patients (N = 586) with non-headache chronic pain completed the questionna...

journal_title：Current medical research and opinion

authors： Portenoy R

更新日期：2006-08-01 00:00:00

abstract：:The efficacy and side-effect profiles of two formulations of indomethacin were compared in a multi-centre, double-blind, crossover study in 77 patients with osteoarthritis. Patients were allocated at random to receive 75 mg indomethacin per day either as 1 controlled-release tablet at night or as 1 immediate-release c...

journal_title：Current medical research and opinion

authors： Bacon P,Luqmani RA,Bossingham DH,Daymond TJ,Grahame R,West J,Hazleman BL,Adebajo AO,Hughes GR,Abdullah M

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:The primary objective of the study was to compare the percentage of men with mean serum total T (C(ave(0-24))) within normal range during the 24-h pharmacokinetic (PK) sampling period on Days 14 and 15. METHODS:Treatment with a new testosterone (T) buccal system, (Striant), 30 mg twice daily was compared to ...

journal_title：Current medical research and opinion

authors： Dobs AS,Matsumoto AM,Wang C,Kipnes MS

更新日期：2004-05-01 00:00:00

abstract：:Abstract Recent guidelines recommend strict goals for low-density lipoprotein cholesterol (LDL-C) (1.8-2.6 mmol/L; 70-100 mg/dL). However, these goals are not always met and many primary and secondary prevention patients are not optimally controlled. Both the under-prescription of lipid-lowering medication and lack of...

journal_title：Current medical research and opinion

authors： Daskalopoulou SS,Doonan RJ,Mikhailidis DP

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The rising prevalence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) and the recent emergence of community-associated MRSA are major clinical, public health, and economic challenges. MRSA is a leading cause of nosocomial pneumonia and complicated skin and soft-tissue infections (cSSTI). Van...

journal_title：Current medical research and opinion

authors： Stein GE,Wells EM

更新日期：2010-03-01 00:00:00

abstract：:Poor nutritional status may impair well being indirectly as a consequence of increased morbidity and decline in functional status. The aim of this study was to examine the independent effect of body mass index on the well being of older people. Thirty one hospital-based patients over 65 years of age were studied. Well...

journal_title：Current medical research and opinion

authors： Balcombe NR,Ferry PG,Saweirs WM

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To compare the effectiveness of 20:1 cafedrine/theodrenaline approved for use in Germany to ephedrine in the restoration of arterial blood pressure and on post-operative outcomes in patients with intra-operative arterial hypotension of any origin under standard clinical practice conditions. METHODS AND RESUL...

journal_title：Current medical research and opinion

authors： Eberhart L,Geldner G,Huljic S,Marggraf K,Keller T,Koch T,Kranke P

更新日期：2018-06-01 00:00:00

abstract：:Objectives: Atopic dermatitis (AD) is a chronic, relapsing skin condition, with signs and symptoms that impact patients' lives and are best measured from the patient perspective. Therefore, there is a need for AD-specific questionnaires that are consistent with Food and Drug Administration guidance and best measuremen...

journal_title：Current medical research and opinion

authors： Foley C,Tundia N,Simpson E,Teixeira HD,Litcher-Kelly L,Bodhani A

更新日期：2019-07-01 00:00:00

abstract：:Background: To investigate the effects of 1-month treatment in addition to standard care with a food supplement containing both Curcuma longa and Boswellia serrata extracts on tendinopathy symptoms. Method: This open-label, non-controlled, post-observational study included 670 patients suffering from tendinopathy recr...

journal_title：Current medical research and opinion

authors： Henrotin Y,Dierckxsens Y,Delisse G,Seidel L,Albert A

更新日期：2020-12-21 00:00:00

abstract：:Daily fluctuations in plasma cortisol levels were studied in three groups of children with rheumatoid arthritis. One group was untreated with hormones, the second treated with a depot preparation of tetracosactrin, and the third group with corticosteroid hormones. The results obtained were compared with the rhythm in ...

journal_title：Current medical research and opinion

authors： Tsvetkova V

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:To assess the safety, tolerability and pharmacokinetics of an interleukin (IL)-12/23 monoclonal antibody (mAb) in subjects with a relapsing form of multiple sclerosis (MS). METHODS:A phase I, double-blind, placebo-controlled, sequential dose escalation study was conducted in 20 subjects with MS. Subjects wer...

journal_title：Current medical research and opinion

authors： Kasper LH,Everitt D,Leist TP,Ryan KA,Mascelli MA,Johnson K,Raychaudhuri A,Vollmer T,Multiple Sclerosis Investigators.

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:The goals of diabetes management have evolved over the past decade to become the attainment of near-normal glucose and cardiovascular risk factor levels. Improved metabolic control is achieved through optimized medication regimens, but costs specifically associated with such optimization have not been examin...

journal_title：Current medical research and opinion

authors： Crivera C,Suh DC,Huang ES,Cagliero E,Grant RW,Vo L,Shin HC,Meigs JB

更新日期：2006-11-01 00:00:00

abstract：:A study was carried out in 15 male volunteers to evaluate qualitatively the secretion of growth factors following stimulation by oral amino acids. The results showed that oral administration of a combination of two amino acids (1200 mg 1-lysine plus 1200 mg 1-arginine) provoked a release of pituitary somatotropin and ...

journal_title：Current medical research and opinion

authors： Isidori A,Lo Monaco A,Cappa M

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Healthcare organizations must evaluate the cost effectiveness of the alternative therapies that are available to treat anemia and improve quality of life (QoL) of patients with cancer, that is, erythropoietic protein therapy and blood transfusion. METHODS:Pharmacoeconomic studies that evaluated the cost of ...

journal_title：Current medical research and opinion

authors： Cornes P,Coiffier B,Zambrowski JJ

更新日期：2007-02-01 00:00:00

abstract：:Two new benzodiazepines, potassium clorazepate (15 mg. at night), and lorazepam (1 mg. t.d.s.) were compared in 50 patients presenting with anxiety in general practice. The response to treatment was assessed clinically and for patient acceptance. The single-dose regime of potassium clorazepate was significantly better...

journal_title：Current medical research and opinion

authors： Harris PG

更新日期：1974-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the positive predictive value of claims-based V85 codes for identifying individuals with varying degrees of BMI relative to their measured BMI obtained from medical record abstraction. METHODS:This was a retrospective validation study utilizing administrative claims and medical chart data from 1 ...

journal_title：Current medical research and opinion

authors： Caplan EO,Kamble PS,Harvey RA,Smolarz BG,Renda A,Bouchard JR,Huang JC

更新日期：2018-01-01 00:00:00

abstract：:Control of hypertension is hindered by the incidence of adverse events associated with therapy, which can result in low patient compliance. Specific angiotensin II receptor subtype AT1 blockers offer an alternative to the angiotensin converting enzyme inhibitors in the treatment of hypertension, as the incidence of si...

journal_title：Current medical research and opinion

authors： Levine B

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To describe a post hoc analysis comparing the effect of a hyaluronic acid (HA)-trehalose solution to an established eyedrop solution containing HA alone using Ocular Surface Disease Index (OSDI) score <19 as a threshold for moderate to severe dry eye disease (DED). METHODS:A phase III, randomized, controlled...

journal_title：Current medical research and opinion

authors： Doan S,Bremond-Gignac D,Chiambaretta F

更新日期：2018-08-01 00:00:00

abstract：:This commentary critically evaluates the limitations of genetic risk predictions in multifactorial disease, with specific reference to age-related macular degeneration (AMD). AMD is a common blinding disease with 33 million people worldwide experiencing vision impairment. Although gene polymorphism combinations infer ...

journal_title：Current medical research and opinion

authors： Feigl B,Morris CP

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Osteoarthritis is one of the most common forms of arthritis seen in primary care. Non-steroidal anti-inflammatory drugs (NSAIDs) play an important role in the management of osteoarthritis. However, gastrointestinal (GI) side effects limit their use. Cyclooxygenase-2 (COX-2) selective inhibitors exhibit better...

journal_title：Current medical research and opinion

authors： Pareek A,Chandanwale AS,Oak J,Jain UK,Kapoor S

更新日期：2006-05-01 00:00:00

abstract：:Fifty-two patients suffering from presumed viral pharyngeal infection or tonsillitis were treated with either benzydamine or placebo oral rinse as a gargle at 3-hourly intervals in a randomized double-blind study. Patients on the active preparation experienced faster resolution of pain and dysphagia and at 7 days 88% ...

journal_title：Current medical research and opinion

authors： Whiteside MW

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:The relationship between chronic pancreatitis (CP) and subsequent pyogenic liver abscess (PLA) is not well understood. METHODS:We investigated the risk of PLA in patients with CP using inpatient claims data from the Taiwan National Health Insurance Program for the period 2000-2010. We identified 17,810 pati...

journal_title：Current medical research and opinion

authors： Tseng CW,Chen YT,Lin CL,Liang JA

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to estimate utility values for hypothetical health states that describe differences in weight and quality of life associated with type 2 diabetes mellitus (DM) from Canadians with type 2 DM. The impact on utility values was examined separately for participants with a body mass ...

journal_title：Current medical research and opinion

authors： Lane S,Levy AR,Mukherjee J,Sambrook J,Tildesley H

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:Patients that undergo total hip replacement (THA) are at risk of revision surgery. This study evaluated the cumulative incidence of revision following a medial collared, triple tapered (MCTT) primary hip stem versus other implants in real-world settings using electronic medical records. METHODS:This was a re...

journal_title：Current medical research and opinion

authors： Chitnis AS,Mantel J,Ruppenkamp J,Bourcet A,Holy CE

更新日期：2020-11-01 00:00:00

abstract：:In gouty patients, urate lowering therapies (ULTs) are recommended to bring serum uric acid (SUA) levels below 6.0 mg/dL, with the aim of dissolving urate depositions, thereby reducing disease impact. However, patients with hyperuricemia often present with other conditions associated with cardiovascular (CV) risk, suc...

journal_title：Current medical research and opinion

authors： Johnson RJ

更新日期：2015-01-01 00:00:00

abstract：:Thirteen young adult patients suffering from heterozygotic familial hypercholesterolaemia with tendinous xanthomatosis, previously treated with a suitable special diet, were studied to assess the effect of bezafibrate, given for 2 years at a dose of 800 mg/day, on plasma lipid and lipoprotein levels and on changes in ...

journal_title：Current medical research and opinion

authors： Rouffy J,Chanu B,Bakir R,Goy-Loeper J,Djian F,Monsuez JJ,Gomberg R,Laval-Jeantet M

更新日期：1988-01-01 00:00:00

abstract：:One hundred and eight patients who had been taking phenytoin for a year or more, either alone or in combination with other drugs, were examined for gum hypertrophy by three observers independently. Approximately 90% of the patients showed either mild or no gum hypertrophy and severe swelling occurred in only 1%. The o...

journal_title：Current medical research and opinion

authors： Grant RH,Parsonage MJ,Barot MH

更新日期：1988-01-01 00:00:00

abstract：:The GRASP (Global Research on Attitudes about hypertension and Stroke Prevention) survey, conducted in 11 countries and involving 825 physicians, was designed to investigate physician perceptions and priorities in the treatment of hypertension and influences on choice of antihypertensive therapy. The prevention of str...

journal_title：Current medical research and opinion

authors： Volpe M,Machado E

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:To explore the clinical effect and radial remodeling of transradial slender 7 Fr sheath for left main bifurcation disease (LM bifurcation). METHODS:From January 2018 to September 2019, 236 patients with LM bifurcation undergoing transradial percutaneous coronary intervention (PCI) from two heart centers were...

journal_title：Current medical research and opinion

authors： Xu Y,Li Y,Shen H,Zhang B,Zhao Q,Cheng Y,Zhao Z,Guo Q,Yang J,Zhou Y

更新日期：2020-10-01 00:00:00