A study of growth hormone release in man after oral administration of amino acids.

Abstract:

:A study was carried out in 15 male volunteers to evaluate qualitatively the secretion of growth factors following stimulation by oral amino acids. The results showed that oral administration of a combination of two amino acids (1200 mg 1-lysine plus 1200 mg 1-arginine) provoked a release of pituitary somatotropin and insulin. This phenomenon was reproducible and the growth hormone secreted in response to this stimulation had biological activity (as demonstrated by a radioreceptor assay and somatomedin induction). The effect appeared to be specific to the combination of the two amino acids; neither of the amino acids demonstrated appreciable stimulating activity when administered alone, even at the same doses.

journal_name

Curr Med Res Opin

authors

Isidori A,Lo Monaco A,Cappa M

doi

10.1185/03007998109114287

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

475-81

issue

7

eissn

0300-7995

issn

1473-4877

journal_volume

7

pub_type

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