Rotigotine transdermal patch in combination therapy for Parkinson's disease--observations in routine clinical practice.

abstract：OBJECTIVE:This observational study was conducted to document the safety of capecitabine-based adjuvant therapy in patients with resected colon cancer under routine clinical conditions. RESEARCH AND DESIGN METHODS:ML20431 was a prospective, multicenter, non-interventional, observational study. It was designed to answer...

journal_title：Current medical research and opinion

authors： Steffens CC,Tschechne B,Schardt C,Jacobs G,Valdix AR,Schmidt P,Hansen R,Kröning H,Wohlfarth T,Guggenberger D

更新日期：2015-04-01 00:00:00

abstract：AIMS:The safety and efficacy of exenatide BID (exenatide) and insulin glargine (glargine) have been studied in clinical trials with few elderly patients. This study examined the clinical effectiveness of exenatide compared to glargine in patients 65 years and older with type 2 diabetes mellitus (T2DM). METHODS:A retro...

journal_title：Current medical research and opinion

authors： Pawaskar M,Li Q,Reynolds MW

更新日期：2012-06-01 00:00:00

abstract：AIMS:Disease management programs (DMP) for diabetes mellitus (DM) or coronary heart disease (CHD) address the treatment of lipid disorders. The current registry aimed to compare drug utilization, lipid lowering effects and further outcomes of outpatients at high cardiovascular risk in DMP for DM or CHD compared to pati...

journal_title：Current medical research and opinion

authors： Gitt AK,Sonntag F,Jannowitz C,Weizel A,Karmann B,Schaefer JR,Pittrow D,Hildemann SK

更新日期：2016-01-01 00:00:00

abstract：:A double-blind, crossover study was carried out in 31 patients with rheumatoid arthritis or osteoarthritis who suffered from insomnia which was considered to be caused primarily by their disease. Patients received 7-day courses of 400 mg chlormezanone, 200 mg chlormezanone and placebo in a pre-determined random order....

journal_title：Current medical research and opinion

authors： Wojtulewski JA,Walter J

更新日期：1983-01-01 00:00:00

abstract：:Forty-nine patients participated in a randomized double-blind, parallel group comparison of beclomethasone dipropionate aqueous nasal spray with terfenadine tablets in the treatment of hay fever. Symptom scores for nasal and ocular symptoms as well as grass pollen counts were registered daily for at least 1 month. Eva...

journal_title：Current medical research and opinion

authors： Beswick KB,Kenyon GS,Cherry JR

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:This study was aimed at comparing efficacy and tolerance of a new hydrocolloid dressing containing hyaluronic acid (HC + HA) to a reference hydrocolloid not containing hyaluronic acid (HC) in the treatment of leg ulcers of venous or mixed origin. RESEARCH DESIGN AND METHODS:This was an open, prospective stud...

journal_title：Current medical research and opinion

authors： Meaume S,Ourabah Z,Romanelli M,Manopulo R,De Vathaire F,Salomon D,Saurat JH

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:To compare the safety and efficacy of celecoxib versus diclofenac slow release (SR) plus omeprazole in elderly arthritis patients. RESEARCH DESIGN AND METHODS:Patients aged≥65 years, with osteoarthritis and/or rheumatoid arthritis, at high gastrointestinal (GI) risk who participated in the CONDOR trial (Cele...

journal_title：Current medical research and opinion

authors： Kellner HL,Li C,Essex MN

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) are the most commonly used pharmacological treatment for gastroesophageal reflux disease (GERD). OBJECTIVE:To examine the utilization patterns of PPIs and other GERD-related medications, satisfaction with PPI treatment and presence of GERD symptoms. PATIENTS AND METHODS:GERD p...

journal_title：Current medical research and opinion

authors： Chey WD,Mody RR,Wu EQ,Chen L,Kothari S,Persson B,Beaulieu N,Lu M

更新日期：2009-08-01 00:00:00

abstract：:Breast cancer was the focus of several presentations during the 27th European Society of Medical Oncology (ESMO) Congress held in Nice. Fulvestrant seems to be equally effective to tamoxifen as a first-line therapy in hormone-sensitive advanced breast cancer in postmenopausal women. However, it may be more effective t...

journal_title：Current medical research and opinion

authors： Mokbel K

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:In the four SMILE (Survival of Myocardial Infarction Long-Term Evaluation) studies, early administration of zofenopril in acute myocardial infarction (AMI) showed beneficial effects as compared to placebo and other angiotensin converting enzyme inhibitors (ACEIs). This study investigated whether the concomita...

journal_title：Current medical research and opinion

authors： Borghi C,Omboni S,Reggiardo G,Bacchelli S,Degli Esposti D,Ambrosioni E,SMILE (Survival of Myocardial Infarction Long-Term Evaluation) Working Project.

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To compare the analgesic efficacy and safety of oxymorphone extended release (ER) and oxycodone controlled release (CR) in patients with moderate to severe cancer pain. RESEARCH DESIGN AND METHODS:This randomized, multicenter, double-blind, 2-period crossover study included adult outpatients (>or= 18 years o...

journal_title：Current medical research and opinion

authors： Gabrail NY,Dvergsten C,Ahdieh H

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:PREDICTIVE is a multi-national, prospective, observational study, assessing the safety and efficacy of insulin detemir in patients with diabetes. RESEARCH DESIGN AND METHODS:The European cohort includes 20,531 patients with diabetes (7420 type 1) from 11 countries. A subgroup of 4782 type 1 patients were tra...

journal_title：Current medical research and opinion

authors： Dornhorst A,Lüddeke HJ,Honka M,Ackermann RW,Meriläinen M,Gallwitz B,Sreenan S,PREDICTIVE Study Group.

更新日期：2008-02-01 00:00:00

abstract：:Oxaprozin (4,5-diphenyl-2-oxazolepropionic acid) is a non-steroidal anti-inflammatory drug (NSAID) which is effective in models of inflammation, pain and pyrexia. It is effective and well tolerated in the clinical management of adult rheumatoid arthritis (RA), osteoarthritis (OA), ankylosing spondylitis, soft tissue d...

journal_title：Current medical research and opinion

authors： Kean WF

更新日期：2004-08-01 00:00:00

abstract：:This paper represents a review, by experts, of current opinion and information on intermittent claudication (IC) and the role that cilostazol plays in its treatment. IC is a common and debilitating condition that has a significant adverse impact on health-related quality of life (HR-QoL). It is currently under-recogni...

journal_title：Current medical research and opinion

authors： Barnett AH,Bradbury AW,Brittenden J,Crichton B,Donnelly R,Homer-Vanniasinkam S,Mikhailidis DP,Stansby G

更新日期：2004-10-01 00:00:00

abstract：:Oesophageal mucosa has well established protective mechanisms, which operate within pre-epithelial, epithelial and post-epithelial compartments. Since refluxed acid and pepsin always act from the luminal side of the mucosa, protective factors like EGF, operating as a part of pre-epithelial defence, are thought to be p...

journal_title：Current medical research and opinion

authors： Marcinkiewicz M,Grabowska SZ,Czyzewska E

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Obesity is one of the major problems of health policy in different countries. Pharmacological attempts have been made to help affected people without a definitive solution. Some agents--either with peripheral or central effect--are available in the market. On July 2012, the FDA approved two novel preparation...

journal_title：Current medical research and opinion

authors： Catoira NP,Viale L,Di Girolamo G,Gonzalez C

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The rising prevalence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) and the recent emergence of community-associated MRSA are major clinical, public health, and economic challenges. MRSA is a leading cause of nosocomial pneumonia and complicated skin and soft-tissue infections (cSSTI). Van...

journal_title：Current medical research and opinion

authors： Stein GE,Wells EM

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical efficacy and safety of mometasone furoate administered via a dry powder inhaler (MF-DPI) in Japanese patients with intermittent or mild persistent asthma who were not previously receiving inhaled corticosteroids. RESEARCH DESIGN AND METHODS:This was an 8-week open-label study conduct...

journal_title：Current medical research and opinion

authors： Tohda Y,Miyamoto T

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:In ST-segment elevation myocardial infarction (STEMI), current guidelines discourage treatment of the non-culprit lesions at the time of the primary intervention. Latest trials have challenged this strategy suggesting benefit of early complete revascularization. We performed a Bayesian multiple treatment net...

journal_title：Current medical research and opinion

authors： Komócsi A,Kehl D,d'Ascenso F,DiNicolantonio J,Vorobcsuk A

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The goals of diabetes management have evolved over the past decade to become the attainment of near-normal glucose and cardiovascular risk factor levels. Improved metabolic control is achieved through optimized medication regimens, but costs specifically associated with such optimization have not been examin...

journal_title：Current medical research and opinion

authors： Crivera C,Suh DC,Huang ES,Cagliero E,Grant RW,Vo L,Shin HC,Meigs JB

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVES:Epidemiological data support an association between age-related macular degeneration (AMD) and cataract surgery that may be attributed to post-operative blue light exposure. By limiting the retina's blue light exposure, new blue-light filtering intraocular lenses (BLF IOLs) have the potential to reduce the d...

journal_title：Current medical research and opinion

authors： Reddy P,Gao X,Barnes R,Fairchild C,Boci K,Waycaster C,Pashos C

更新日期：2006-07-01 00:00:00

abstract：:Type 2 diabetes mellitus is a public health problem of epidemic proportions and its prevalence is on the rise. The typical American born today has a one in three chance of developing type 2 diabetes. This diagnosis is associated with an adverse cardiovascular prognosis and is considered the risk equivalent of establis...

journal_title：Current medical research and opinion

authors： Abuissa H,Bel DS,O'keefe JH Jr

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To analyze the construct validity of the EQ-5D in patients with acute coronary syndromes (ACS). METHODS:All ACS-diagnosed patients discharged from a university-affiliated hospital during a 3-year period were mailed a questionnaire that included the EQ-5D and the SF-8. The EQ-5D includes a visual analogue sca...

journal_title：Current medical research and opinion

authors： Ellis JJ,Eagle KA,Kline-Rogers EM,Erickson SR

更新日期：2005-08-01 00:00:00

abstract：:Objective: Type 2 diabetes (T2D) is a prevalent health problem. Oral agents, with the exception of metformin, are often discontinued with the initiation of insulin. The objective was to understand the proportion of patients discontinuing dipeptidyl peptidase-4 inhibitors (DPP-4is) and the reasons for the decision to d...

journal_title：Current medical research and opinion

authors： Fernandes G,Matos JE,Jaffe DH,Beyer G,Yang L,Iglay K,Gantz I,Rajpathak S

更新日期：2020-03-01 00:00:00

abstract：:The efficacy of parenteral mecillinam was evaluated in 105 elderly patients with lower respiratory tract infections or urinary tract infections. Another antibiotic, usually amoxycillin, was given concurrently in cases of respiratory infection. An adequate response was note in 86% of chest infections and in all of the ...

journal_title：Current medical research and opinion

authors： Pines A,Raafat H,Khorasani MH,Sharma JC,Menday AP

更新日期：1981-01-01 00:00:00

abstract：:A double-blind crossover study was carried out in 24 patients with rheumatoid arthritis to investigate the relative efficacy of tolmetin (1600 mg/day) and phenylbutazone (400 mg/day). Each drug was given for 4 weeks, preceded by a 2-week wash-out period during which patients received paracetamol alone for pain relief....

journal_title：Current medical research and opinion

authors： Cardoe N,Steele CE

更新日期：1976-01-01 00:00:00

abstract：:Objective: To examine the potential sociodemographic disparities in type 2 diabetes (T2D) management and care among US adult individuals, after controlling for clinical and behavioral factors.Methods: This was a retrospective cohort study of individuals with T2D (N = 4552) from a linked database of the National Health...

journal_title：Current medical research and opinion

authors： Tan X,Lee LK,Huynh S,Pawaskar M,Rajpathak S

更新日期：2020-06-01 00:00:00

abstract：:A double-blind, parallel group study was carried out in 50 patients with an anxiety disorder to compare the anxiolytic efficacy and tolerability of a recently developed benzodiazepine, metaclazepam, with that of bromazepam. Patients were allocated at random to receive treatment for 2 weeks with either 15 mg metaclazep...

journal_title：Current medical research and opinion

authors： Marano P,Patti F,Nicoletti F

更新日期：1988-01-01 00:00:00

abstract：:A double-blind, placebo-controlled trial was carried out to assess the effectiveness of a new synthetic bioflavonoid, hidrosmin, in patients with chronic venous insufficiency of the lower limbs. Fifty-seven patients, showing varicose veins and ankle swelling and suffering from local pain and heaviness of the legs, wer...

journal_title：Current medical research and opinion

authors： Domínguez C,Brautigam I,González E,González JA,Nazco J,Valiente R,Boada J

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To determine whether the efficacy and tolerability of adjunctive lamotrigine differ as a function of whether persons with mental retardation and refractory epilepsy resided in institutions or the community. RESEARCH DESIGN AND METHODS:The analysis was retrospective and employed data from a previously publish...

journal_title：Current medical research and opinion

authors： Sunder TR,McKee JR,Hammer AE,Vuongc A

更新日期：2006-04-01 00:00:00