Sociodemographic disparities in the management of type 2 diabetes in the United States.

abstract：OBJECTIVE:To analyze the effect of brexpiprazole on metabolic parameters and body weight in adults with schizophrenia, including clinically relevant sub-groups of patients, based on data from two pivotal phase 3 studies (NCT01393613; NCT01396421) and a long-term extension study (NCT01397786). METHODS:The short-term st...

journal_title：Current medical research and opinion

authors： Newcomer JW,Eriksson H,Zhang P,Weiller E,Weiss C

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Patients that undergo total hip replacement (THA) are at risk of revision surgery. This study evaluated the cumulative incidence of revision following a medial collared, triple tapered (MCTT) primary hip stem versus other implants in real-world settings using electronic medical records. METHODS:This was a re...

journal_title：Current medical research and opinion

authors： Chitnis AS,Mantel J,Ruppenkamp J,Bourcet A,Holy CE

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To examine outcomes associated with colesevelam treatment among patients with hypercholesterolemia in real-world clinical practice. METHODS:This analysis was conducted as a retrospective, observational cohort study in an ambulatory-care medical network in Northern California. Patients with orders for colesev...

journal_title：Current medical research and opinion

authors： Romanelli RJ,Leahy A,Jukes T,Ye X,Qian C,Ishisaka DY

更新日期：2013-12-01 00:00:00

abstract：:Objectives: The purpose of this study was to assess (1) the trends of and (2) the factors associated with health information technology (HIT) use among older adults in the U.S.Methods: A decade (2009-2018) of data from the U.S. National Health Interview Survey (NHIS) was used. The trends of HIT use among older adults ...

journal_title：Current medical research and opinion

authors： Hung LY,Lyons JG,Wu CH

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:To investigate the efficacy of pantoprazole 20 mg once daily (o.d.) in relieving epigastric pain associated with ulcer-like functional dyspepsia. RESEARCH DESIGN AND METHODS:In this double-blind, placebo-controlled, multicentre study, patients experiencing ulcer-like functional dyspepsia, with epigastric pai...

journal_title：Current medical research and opinion

authors： van Rensburg C,Berghöfer P,Enns R,Dattani ID,Maritz JF,Gonzalez Carro P,Fischer R,Schwan T

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:The best management of patients with femoropopliteal and infrapopliteal artery occlusion disease is not clear. This study aimed to compare the efficacy of drug-coated balloons (DCBs) and drug-eluting stents (DESs) with percutaneous transluminal angioplasty (PTA) in patients with femoropopliteal or infrapoplit...

journal_title：Current medical research and opinion

authors： Chen X,Li J,Zheng C,He Y,Jia J,Wang X,Li D,Shang T,Li M

更新日期：2018-01-01 00:00:00

abstract：:The pharmacokinetics of Bay g 2821, a new diuretic agent, were studied in dogs, healthy volunteers and in patients with renal insufficiency. The drug was rapidly absorbed after oral administration, peak plasma levels (approx. 0.4 microgram/ml) occurring within 1 hour. Elimination of the unchanged drug from plasma was ...

journal_title：Current medical research and opinion

authors： Ritter W

更新日期：1977-01-01 00:00:00

abstract：:Elevated serum cholesterol level is a key risk factor for cardiovascular morbidity and mortality. Cerivastatin is a highly effective lipid-lowering agent currently licensed at doses of 0.1, 0.2, 0.3 and 0.4 mg. This was a multicentre, randomised, double-blind, parallel-group study comparing the efficacy and safety of ...

journal_title：Current medical research and opinion

authors： Ose L,Luurila O,Eriksson J,Olsson A,Lithell H,Widgren B

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:It has been postulated that intraocular pressure, an important glaucoma risk factor, correlates positively with arterial blood pressure (blood pressure). However, results of experimental and clinical studies are often contradictory. It is hypothesized that, in some hypertensive patients, disturbances in intr...

journal_title：Current medical research and opinion

authors： Skrzypecki J,Grabska-Liberek I,Przybek J,Ufnal M

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Long-term oral corticosteroid (OCS) therapy and related adverse events are associated with a significant burden on patients and healthcare resources. METHODS:This subgroup analysis of a randomized, open-label, parallel-group study evaluated the OCS-sparing effect of omalizumab (OMA) added to optimized asthm...

journal_title：Current medical research and opinion

authors： Siergiejko Z,Świebocka E,Smith N,Peckitt C,Leo J,Peachey G,Maykut R

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:The Exenatide BID Observational Study (ExOS) was designed to evaluate the clinical effectiveness of exenatide BID use in patients with type 2 diabetes (T2D) in a real-world clinical practice setting in the United States. METHODS:Patients were enrolled from 74 practice sites from 9/2007 through 1/2009 and fol...

journal_title：Current medical research and opinion

authors： Bergenstal RM,Garrison LP Jr,Miller LA,Hou L,Blickensderfer A,Zagar A,Stanley S,Bhargava A,Wade R,Herman WH

更新日期：2011-12-01 00:00:00

abstract：:Cardiac arrhythmias are the most common cardiac complication reported in pregnant women with and without structural heart disease (SHD); they are more frequent among women with SHD, such as cardiomyopathy and congenital heart disease (CHD). While older studies had indicated supraventricular tachycardia as the most com...

journal_title：Current medical research and opinion

authors： Manolis TA,Manolis AA,Apostolopoulos EJ,Papatheou D,Melita H,Manolis AS

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:Poor quality has been reported for some generics and other copies of original products. We performed a pilot study to compare the disintegration/dissolution profiles of FOSAMAX (alendronate) 70 mg tablets with those of copies of FOSAMAX that were manufactured outside the United States. RESEARCH DESIGN AND ME...

journal_title：Current medical research and opinion

authors： Epstein S,Cryer B,Ragi S,Zanchetta JR,Walliser J,Chow J,Johnson MA,Leyes AE

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:There is a general perception that research is underdeveloped in rehabilitation professions. However, a PubMed search found that the growth in publications in the rehabilitation field was twice that of the general medical field. Despite this growth, another study focusing on Europe found that the proportion ...

journal_title：Current medical research and opinion

authors： Decullier E,Tourmente B,Dessez B,Guilhot N,Witko A

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Using a Delphi Consultation process, a group of medical writers established by the European Medical Writers Association (EMWA) set out to determine the current thinking on the problems of ghostwriting in medical publications and what should be done about them. In this context, ghostwriting is where a professi...

journal_title：Current medical research and opinion

authors： Jacobs A,Carpenter J,Donnelly J,Klapproth JF,Gertel A,Hall G,Jones AH,Laing S,Lang T,Langdon-Neuner E,Wager L,Whittington R,European Medical Writers Association's Ghostwriting Task Force.

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Venous thromboembolism (VTE), which includes deep vein thrombosis and pulmonary embolism (PE), is a major cause of morbidity and mortality. VTE is a common disorder, with an estimated annual incidence of approximately 5-12 persons per 10,000. The prognosis for patients who develop VTE is exacerbated by the r...

journal_title：Current medical research and opinion

authors： Ruppert A,Lees M,Steinle T

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Latinos are the largest minority population in the United States, and are characterized by higher rates of obesity and diabetes compared to Whites. The prevalence of diagnosed diabetes in Latinos is two-fold higher than in Caucasians, and Latinos suffer from higher rates of diabetic complications and mortali...

journal_title：Current medical research and opinion

authors： Gonzalez AB,Salas D,Umpierrez GE

更新日期：2011-05-01 00:00:00

abstract：:Optimal management of hypertension has been shown to reduce the risk of stroke. In recent years, newer classes of antihypertensive such as the angiotensin II (Ang II) antagonists have become available. Results from the Losartan Intervention for Endpoint reduction in hypertension (LIFE) study suggest the utility of thi...

journal_title：Current medical research and opinion

authors： Ferrario CM

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVES:Docetaxel and paclitaxel show significant clinical activity in metastatic breast cancer (MBC) and have been approved for MBC by the U.S. Food and Drug Administration, but it is still unclear whether a paclitaxel-based regimen improves outcomes over a docetaxel-based regimen in patients with MBC. We therefore...

journal_title：Current medical research and opinion

authors： Qi WX,Shen Z,Lin F,Sun YJ,Min DL,Tang LN,He AN,Yao Y

更新日期：2013-02-01 00:00:00

abstract：:A national survey of psychotherapeutic drug use was carried out in the U.S.A. in 1979. Data were obtained from a probability sample (n = 3161) of adults in the general population, using a clinically-oriented interview lasting an average of 90 minutes. The data provide estimates of the prevalence of using anxiolytic an...

journal_title：Current medical research and opinion

authors： Mellinger GD,Balter MB,Uhlenhuth EH

更新日期：1984-01-01 00:00:00

abstract：:Critical thinking is crucially important in both research and practice. This article demonstrates that a lack of critical thinking in two meta-analyses resulted in a conclusion that contradicts another meta-analysis and popular opinions. Kahwati et al. and Zhao et al. drew a conclusion that "Vitamin D supplementation ...

journal_title：Current medical research and opinion

authors： Fan H,Xiao J

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:To report the long-term effect of the dorzolamide/timolol (DTFC) and latanoprost/timolol (LTFC) fixed combinations on intraocular pressure (IOP) and visual field defects over time in naïve primary open-angle glaucoma (POAG) patients. STUDY DESIGN AND METHODS:Prospective, 4-year, open-label, interventional st...

journal_title：Current medical research and opinion

authors： Pajic B,Pajic-Eggspuehler B,Häfliger IO

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:We evaluated the clinical efficacy of sacubitril/valsartan in a group of ambulatory patients with heart failure (HF) with reduced ejection fraction (HFrEF) referred to our HF clinic. METHODS:Patients (n = 29; 72% males; mean age 76 years) with HFrEF in New York Heart Association (NYHA) classes II-III were in...

journal_title：Current medical research and opinion

authors： Cosentino ER,Degli Esposti D,Miceli R,Bentivenga C,Landolfo M,Fg Cicero A,Berardi E,Spinardi L,Magri G,Dugato V,Borghi C

更新日期：2019-03-01 00:00:00

abstract：:Objectives Real-world patient outcomes data is scarce concerning the high disease burden of IBS-C. The aim of this study was to compare patient-reported symptom control, health-related quality of life (HRQoL), resource utilization, and treatment satisfaction of lubiprostone vs non-lubiprostone treatment for irritable ...

journal_title：Current medical research and opinion

authors： Solem CT,Patel H,Mehta S,Mody R,Macahilig C,Gao X

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Adherence to antihyperglycemic medication is thought to be suboptimal, but the proportion of patients missing doses, the number of doses missed, and reasons for missing are not well described. This survey was conducted to estimate the prevalence of and reasons for missed doses of oral antihyperglycemic medic...

journal_title：Current medical research and opinion

authors： Vietri JT,Wlodarczyk CS,Lorenzo R,Rajpathak S

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:Most registration studies for new osteoporosis drugs have used a combination of quantitative morphometry (QM) and visual semiquantitative reading (SQ) to define vertebral fractures. However, in the pivotal teriparatide Fracture Prevention Trial (ClinicalTrials.gov Identifier: NCT00670501), vertebral fractures...

journal_title：Current medical research and opinion

authors： Prevrhal S,Krege JH,Chen P,Genant H,Black DM

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVES:Compare costs and healthcare resource utilization (HCRU) among newly-diagnosed non-valvular atrial fibrillation (NVAF) patients newly treated with dabigatran vs apixaban, rivaroxaban, or warfarin. METHODS:Newly-diagnosed adult NVAF patients initiating dabigatran, apixaban, rivaroxaban, or warfarin (index ev...

journal_title：Current medical research and opinion

authors： Gilligan AM,Franchino-Elder J,Song X,Wang C,Henriques C,Sainski-Nguyen A,Wilson K,Smith DM,Sander S

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To investigate the predictive factors associated with physical impairment among older patients with type 2 diabetes mellitus (T2DM) in Japan and to examine the potential impact of physical impairment on patient-reported health outcomes in this population. METHODS:A cross-sectional analysis was conducted usin...

journal_title：Current medical research and opinion

authors： Araki A,Umegaki H,Sakurai T,Mizuno Y,Miyao M,Imori M,Suzuki S,Cambron-Mellott MJ,Yokote K,Onuma T,Yokono K

更新日期：2020-11-23 00:00:00

abstract：OBJECTIVE:Self-reported healthcare resource utilization (HRU), medication out-of-pocket (OOP) expenditures and impact of OOP expenses on HRU were assessed for respondents with type 2 diabetes mellitus (T2DM) or elevated cardiometabolic risk. METHODS:The 5-year longitudinal SHIELD study surveyed a stratified sample of ...

journal_title：Current medical research and opinion

authors： Fox KM,Grandy S,SHIELD Study Group.

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:Aliskiren is the first in a new class of orally effective direct renin inhibitors approved for the treatment of hypertension. This multiple-dose study investigated the potential for pharmacokinetic interactions between aliskiren and three drugs, each predominantly eliminated by a different clearance/metabolic...

journal_title：Current medical research and opinion

authors： Ayalasomayajula S,Tchaloyan S,Yeh CM,Bizot MN,Dieterich HA,Howard D,Dole WP

更新日期：2008-03-01 00:00:00