Verteporfin therapy in combination with triamcinolone: published studies investigating a potential synergistic effect.

abstract：BACKGROUND AND OBJECTIVES:Reduction in total cholesterol (TC) and LDL-cholesterol (LDL-C) forms one of the principal objectives of most cardiovascular secondary prevention strategies. Many patients being treated with statins, however, have significant residual dyslipidaemia, with many having suboptimal HDL-cholesterol ...

journal_title：Current medical research and opinion

authors： Belsey J,de Lusignan S,van Vlymen J,Chan T,Hague N

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Decision aids (DAs) are increasingly used to operationalize shared decision-making (SDM) but their development is not often described. Decisions about oral anticoagulants (OACs) for atrial fibrillation (AF) involve a trade-off between lowering stroke risk and increasing OAC-associated bleeding risk, and consi...

journal_title：Current medical research and opinion

authors： Kaiser K,Cheng WY,Jensen S,Clayman ML,Thappa A,Schwiep F,Chawla A,Goldberger JJ,Col N,Schein J

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:There is a general perception that research is underdeveloped in rehabilitation professions. However, a PubMed search found that the growth in publications in the rehabilitation field was twice that of the general medical field. Despite this growth, another study focusing on Europe found that the proportion ...

journal_title：Current medical research and opinion

authors： Decullier E,Tourmente B,Dessez B,Guilhot N,Witko A

更新日期：2020-11-01 00:00:00

abstract：:The therapeutic efficacy and tolerability of a new controlled-release 1000 mg tablet of naproxen (naproxen CR) were compared with 200 mg isoxicam in 100 out-patients with osteoarthritis. Medications were administered once daily for 4 weeks in a controlled, randomized, double-blind, parallel trial. Patients were assess...

journal_title：Current medical research and opinion

authors： Frankhof W

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Basal cell carcinoma (BCC) is the most common cancer. Most cases of BCCs are treated with only optimal surgical resection. However, unresectable, locally advanced or metastatic tumors might have potential to progress. In this patient group, there is no standardized treatment approach. Vismodegib is a new sel...

journal_title：Current medical research and opinion

authors： Erdem GU,Sendur MA,Ozdemir NY,Yazıcı O,Zengin N

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the relative bioavailability of a new formulation containing 5 mg mosapride and 10 mg rabeprazole (T) and compare it with the branded formulations of both drugs co-administered in separate tablets (R) to meet the regulatory requirements of bioequivalence in Argentina. METHODS:A randomized-sequenc...

journal_title：Current medical research and opinion

authors： Keller GA,Czerniuk P,Bertuola R,de Mena F,Simoni MV,Assefi AR,Di Girolamo G

更新日期：2011-11-01 00:00:00

abstract：:Seventy frail elderly patients attending a day hospital were studied to investigate the incidence of postural hypotension in control patients on no diuretic treatment (n = 30), patients on loop diuretics (frusemide) for mild cardiac failure (n = 20) and patients on thiazide diuretics for mild cardiac failure (n = 20)....

journal_title：Current medical research and opinion

authors： Heseltine D,Bramble MG

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Stroke is a major cause of disability. Certain experimental studies have suggested that a combination of almitrine + raubasine (Duxil) increases the supply of oxygen to cerebral tissues and may be beneficial in post-stroke rehabilitation. This multicentre clinical study was carried out in orde...

journal_title：Current medical research and opinion

authors： Li S,Long J,Ma Z,Xu Z,Li J,Zhang Z

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is the most common arrhythmia in clinical practice and is associated with increased cardiovascular morbidity and mortality. Epicardial adipose tissue (EAT) serves as a biologically active organ with important endocrine and inflammatory function. Review An accumulating body of evidenc...

journal_title：Current medical research and opinion

authors： Goudis CA,Vasileiadis IE,Liu T

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Most patients with hypertension require more than one drug to attain recommended blood pressure (BP) targets. Initiating therapy with two agents is recommended for patients at high risk of a cardiovascular event or with a BP > 20/10 mmHg above goal. Combination therapy is effective when comprised of agents w...

journal_title：Current medical research and opinion

authors： Ram CV

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:We conducted an adjusted comparison of progression-free survival (PFS) and overall survival (OS) for daratumumab monotherapy versus standard of care, as observed in a real-world historical cohort of heavily pretreated multiple myeloma patients from Czech Republic. METHODS:Using longitudinal chart data from ...

journal_title：Current medical research and opinion

authors： Jelínek T,Maisnar V,Pour L,Špička I,Minařík J,Gregora E,Kessler P,Sýkora M,Fraňková H,Adamová D,Wróbel M,Mikula P,Jarkovský J,Diels J,Gatopoulou X,Veselá Š,Besson H,Brožová L,Ito T,Hájek R

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Osteoarthritis is one of the most common forms of arthritis seen in primary care. Non-steroidal anti-inflammatory drugs (NSAIDs) play an important role in the management of osteoarthritis. However, gastrointestinal (GI) side effects limit their use. Cyclooxygenase-2 (COX-2) selective inhibitors exhibit better...

journal_title：Current medical research and opinion

authors： Pareek A,Chandanwale AS,Oak J,Jain UK,Kapoor S

更新日期：2006-05-01 00:00:00

abstract：:Faecal blood loss arising from tenoxicam at a dose of 20 mg/day was compared to that arising from piroxicam at a dose of 20 mg/day in a double-blind, parallel comparative study in 12 healthy male volunteers. Faecal blood loss was measured for a 1-week run-in on placebo, during 4 weeks of treatment and for a 2-week pos...

journal_title：Current medical research and opinion

authors： Bird HA,Hill J,Haw WM,Dixon JS,Harris PA,Wright V

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Reducing low-density lipoprotein cholesterol (LDL-C) levels to National Cholesterol Expert Panel (NCEP) goal is recommended. However, sex-specific effects may influence benefit. METHODS AND RESULTS:In this post hoc analysis of the GREek Atorvastatin and Coronary heart disease (CHD) Evaluation [GREACE] study...

journal_title：Current medical research and opinion

authors： Athyros VG,Kakafika AI,Papageorgiou AA,Paraskevas KI,Tziomalos K,Anagnostis P,Pagourelias E,Koumaras C,Karagiannis A,Mikhailidis DP

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Severe allergic asthma patients may not be controlled even with guideline recommended care, including inhaled corticosteroids, long-acting beta-2 agonists, theophylline, oral steroids and anti-leukotrienes. They experience exacerbations requiring intensive healthcare use and which may be fatal. Omalizumab, a...

journal_title：Current medical research and opinion

authors： Dewilde S,Turk F,Tambour M,Sandström T

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Obesity is one of the major problems of health policy in different countries. Pharmacological attempts have been made to help affected people without a definitive solution. Some agents--either with peripheral or central effect--are available in the market. On July 2012, the FDA approved two novel preparation...

journal_title：Current medical research and opinion

authors： Catoira NP,Viale L,Di Girolamo G,Gonzalez C

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Patients with hypereosinophilic syndrome (HES) vary considerably in their clinical presentation with regard to the severity and pattern of end-organ involvement. Clinical manifestations range from nonspecific symptoms to life-threatening, multisystem damage caused by eosinophil infiltration and local release...

journal_title：Current medical research and opinion

authors： Schwartz LB,Sheikh J,Singh A

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the effect of gliclazide modified release (MR) treatment on adiponectin, interleukin 6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha) plasma concentrations in type 2 diabetic patients. RESEARCH DESIGN AND METHODS:24 randomly selected type 2 diabetic patients, aged 61...

journal_title：Current medical research and opinion

authors： Drzewoski J,Zurawska-Klis M

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:Neuropathic pain is often difficult to treat due to a complex pathophysiology. This study evaluated the efficacy, tolerability and safety of combination therapy with 5% lidocaine medicated plaster and pregabalin for neuropathic pain in patients with post-herpetic neuralgia (PHN) or painful diabetic polyneurop...

journal_title：Current medical research and opinion

authors： Baron R,Mayoral V,Leijon G,Binder A,Steigerwald I,Serpell M

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To conduct a preliminary evaluation of a new oral formulation of controlled-release (CR) oxybutynin tablet taken once-daily in patients with urinary urge incontinence. RESEARCH DESIGN AND METHODS:A single-centre, open-label, 8-week study was conducted. Patients with urodynamically-confirmed detrusor instabil...

journal_title：Current medical research and opinion

authors： Radomski SB,Caley B,Reiz JL,Miceli PC,Harsanyi Z,Darke AC

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Neurosurgery often requires skull immobilization with a Mayfield clamp, which often causes brief intense nociceptive stimulation, hypertension and tachycardia. Blunting this response may help prevent increased intracranial pressure, cerebral aneurysm or vascular malformation rupture, and/or myocardial stress....

journal_title：Current medical research and opinion

authors： Berger M,Philips-Bute B,Guercio J,Hopkins TJ,James ML,Borel CO,Warner DS,McDonagh DL

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:This meta-analysis compared the median overall survival (mOS) of brentuximab vedotin reported in the pivotal phase 2 study with published results of other therapies for the treatment of relapsed/refractory (R/R) Hodgkin lymphoma (HL) post autologous stem cell transplant (ASCT). RESEARCH DESIGN AND METHODS:A ...

journal_title：Current medical research and opinion

authors： Bonthapally V,Yang H,Ayyagari R,Tan RD,Cai S,Wu E,Gautam A,Chi A,Huebner D

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:As results from an increasing number of clinical trials with disease-modifying drugs (DMDs) in multiple sclerosis (MS) become available, the challenge for the treating neurologist is how to decide on the appropriate therapy for an individual patient. OBJECTIVE:An International Working Group for Treatment Op...

journal_title：Current medical research and opinion

authors： Goodin DS,Biermann LD,Bohlega S,Boiko A,Chofflon M,Gebeily S,Gouider R,Havrdova E,Jakab G,Karabudak R,Karussis D,Miller A,Pakdaman H,Selmaj K,Sharief M,International Working Group for Treatment Optimization in MS.

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To compare safety and efficacy of biphasic insulin aspart 70/30 (BIAsp 30) with exenatide in subjects with type 2 diabetes mellitus (T2DM) not achieving glycemic targets with metformin and sulfonylurea in a randomized, open-label, 24-week trial. RESEARCH DESIGN AND METHODS:Subjects (N = 372, T2DM > 6 months,...

journal_title：Current medical research and opinion

authors： Bergenstal R,Lewin A,Bailey T,Chang D,Gylvin T,Roberts V,NovoLog Mix-vs.-Exenatide Study Group.

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To compare the analgesic efficacy and safety of oxymorphone extended release (ER) and oxycodone controlled release (CR) in patients with moderate to severe cancer pain. RESEARCH DESIGN AND METHODS:This randomized, multicenter, double-blind, 2-period crossover study included adult outpatients (>or= 18 years o...

journal_title：Current medical research and opinion

authors： Gabrail NY,Dvergsten C,Ahdieh H

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To compare clinical characteristics, statin treatment patterns and adherence among patients at different risk for coronary heart disease (CHD) as defined by National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III guidelines. METHODS:Patients ≥ 18 years old with ≥ 1 claim for dyslipidemi...

journal_title：Current medical research and opinion

authors： Kern DM,Balu S,Tunceli O,Anzalone D

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To describe the epidemiology and trends in pediatric gastrointestinal (GI) bleeding associated emergency department (ED) visits in the US. METHODS:Estimates of GI bleeding associated ED visits were calculated in children from birth to 19 years of age using the Nationwide Emergency Department Sample (NEDS). ...

journal_title：Current medical research and opinion

authors： Pant C,Olyaee M,Sferra TJ,Gilroy R,Almadhoun O,Deshpande A

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Consensus health panels, including the Joint British Societies (JBS), have established increasingly stringent cholesterol goals. However, in clinical settings, most patients do not achieve even the less stringent goals. OBJECTIVE:To provide descriptive data on the proportion of patients in the United Kingdo...

journal_title：Current medical research and opinion

authors： Rajagopalan S,Alemao E,Finch L,Yin D

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVES:In ST-segment elevation myocardial infarction (STEMI), current guidelines discourage treatment of the non-culprit lesions at the time of the primary intervention. Latest trials have challenged this strategy suggesting benefit of early complete revascularization. We performed a Bayesian multiple treatment net...

journal_title：Current medical research and opinion

authors： Komócsi A,Kehl D,d'Ascenso F,DiNicolantonio J,Vorobcsuk A

更新日期：2017-03-01 00:00:00

abstract：:In an electropharmacokinetic study, the effects of lormetazepam and flunitrazepam were compared by the means of a sleep EEG and waking EEG during the following daytime. At a 1-week interval, 6 normal subjects received at random either 2 mg lormetazepam or 2 mg flunitrazepam in a double-blind, crossover fashion. Sleep ...

journal_title：Current medical research and opinion

authors： Timsit-Berthier M,de Thier D,Machowsky R,Mantanus H,Rousseau JC

更新日期：1985-01-01 00:00:00