Lorazepam as a sedative-amnesic in an intensive care unit.

abstract：OBJECTIVE:Statins are hypothesized to have beneficial effects in asthma management through their pleiotropic anti-inflammatory effects. Several studies have examined this relationship, but have yielded conflicting results. This study investigates the effect of statin use on asthma-related hospitalizations and/or emerge...

journal_title：Current medical research and opinion

authors： Tse SM,Charland SL,Stanek E,Herrera V,Goldfarb S,Litonjua AA,Weiss ST,Wu AC

更新日期：2014-04-01 00:00:00

abstract：:The sensitivity of a number of beta-lactamase producing strains of Enterobacter aerogenes, Enterobacter cloacae, Enterobacter species, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Proteus mirabilis, Proteus vulgaris, Pseudomonas aeruginosa and Serratia marcescens to cefamandole, cefoxitin, cefuroxi...

journal_title：Current medical research and opinion

authors： Kuipers JS

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:To estimate the proportion of patients with moderate to severe chronic kidney disease (CKD) whose initial dipeptidyl-peptidase-4 inhibitor (DPP4-i) dosage was concordant with prescribing information (label) recommendations in the United States. METHODS:Adult patients with type 2 diabetes mellitus (T2DM) who ...

journal_title：Current medical research and opinion

authors： Huang H,Shetty S,Bauer E,Lang K

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:Cardiovascular disease (CVD) is the leading cause of mortality worldwide. A high level of low-density lipoprotein cholesterol (LDL-C) is a major CVD risk factor. Guidelines recommend effective cholesterol management and set LDL-C goals, yet deficiencies exist in physician implementation of these recommendati...

journal_title：Current medical research and opinion

authors： Hobbs FD,Erhardt LR,Rycroft C,Heart study investigators.

更新日期：2008-05-01 00:00:00

abstract：:Objective: To assess real-world costs for patients with hemophilia A treated with bypassing agents versus factor VIII (FVIII) replacement. Methods: Claims data from a large US health insurer during 1 January 2006-30 September 2014 were used for analysis. Treated patients with hemophilia A were identified based on ≥1 m...

journal_title：Current medical research and opinion

authors： Swindle JP,Xu Y,Mu Y,Solari PG

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:This retrospective study assessed the incidence and timing of adverse events (AEs) among patients prescribed varying dose levels of corticosteroids in the US. METHODS:Patients with selected autoimmune or inflammatory disease diagnoses between 2006 and 2015 were identified from a privately insured administrat...

journal_title：Current medical research and opinion

authors： Rice JB,White AG,Johnson M,Wagh A,Qin Y,Bartels-Peculis L,Ciepielewska G,Nelson WW

更新日期：2018-08-01 00:00:00

abstract：:In gouty patients, urate lowering therapies (ULTs) are recommended to bring serum uric acid (SUA) levels below 6.0 mg/dL, with the aim of dissolving urate depositions, thereby reducing disease impact. However, patients with hyperuricemia often present with other conditions associated with cardiovascular (CV) risk, suc...

journal_title：Current medical research and opinion

authors： Johnson RJ

更新日期：2015-01-01 00:00:00

abstract：:Evidence is needed to guide therapeutic decisions on patients who had ischaemic cerebral events. The recently published European/Australasian Stroke Prevention in Reversible Ischaemia Trial (ESPRIT), an open-label randomised controlled study, compared long-term treatment of patients randomised to aspirin 30-325 mg dai...

journal_title：Current medical research and opinion

authors： Einhäupl K

更新日期：2007-02-01 00:00:00

abstract：:A national survey of psychotherapeutic drug use was carried out in the U.S.A. in 1979. Data were obtained from a probability sample (n = 3161) of adults in the general population, using a clinically-oriented interview lasting an average of 90 minutes. The data provide estimates of the prevalence of using anxiolytic an...

journal_title：Current medical research and opinion

authors： Mellinger GD,Balter MB,Uhlenhuth EH

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:Subcutaneous immunotherapy (SCIT) for allergic rhinitis (AR) has been shown to control symptoms for up to several years following treatment discontinuation, but the effect of SCIT on healthcare costs for commercially insured patients is unknown. The objective of this study was to compare healthcare costs and ...

journal_title：Current medical research and opinion

authors： Allen-Ramey F,Mao J,Blauer-Peterson C,Rock M,Nathan R,Halpern R

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the influence of age, sex, and previous opioid experience on the likelihood of successfully titrating opioid-naive and experienced patients with chronic low back pain (CLBP) to an effective and well-tolerated dose of oxymorphone extended release (ER). METHODS:Post hoc analysis of open-label titra...

journal_title：Current medical research and opinion

authors： Peniston JH,Xiang Q,Gould EM

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:To assess the burden of treatment-resistant depression (TRD) among privately insured patients with anxiety disorder and/or substance use disorders (SUD). METHODS:Adults <65 years old were identified in the Optum Health Care Solutions Inc. database (July 2009-March 2017). Among those with major depressive dis...

journal_title：Current medical research and opinion

authors： Zhdanava M,Kuvadia H,Joshi K,Daly E,Pilon D,Rossi C,Morrison L,Lefebvre P,Nelson C

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:Compare costs and healthcare resource utilization (HCRU) among newly-diagnosed non-valvular atrial fibrillation (NVAF) patients newly treated with dabigatran vs apixaban, rivaroxaban, or warfarin. METHODS:Newly-diagnosed adult NVAF patients initiating dabigatran, apixaban, rivaroxaban, or warfarin (index ev...

journal_title：Current medical research and opinion

authors： Gilligan AM,Franchino-Elder J,Song X,Wang C,Henriques C,Sainski-Nguyen A,Wilson K,Smith DM,Sander S

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:Azole antifungal agents are often coadministered with immunosuppressants to recipients of solid organ and hematopoietic stem cell transplants. Posaconazole, an extended-spectrum triazole, is an inhibitor of the cytochrome P450 (CYP) isoenzyme CYP3A4, and sirolimus, an immunosuppressant, is a substrate of the...

journal_title：Current medical research and opinion

authors： Moton A,Ma L,Krishna G,Martinho M,Seiberling M,McLeod J

更新日期：2009-03-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the elderly, characterised by widespread loss of central cholinergic function. The only symptomatic treatment proven effective to date is the use of cholinesterase (ChE) inhibitors to augment surviving cholinergic activity. ChE inhibitors act on t...

journal_title：Current medical research and opinion

authors： Greig NH,Utsuki T,Yu Q,Zhu X,Holloway HW,Perry T,Lee B,Ingram DK,Lahiri DK

更新日期：2001-01-01 00:00:00

abstract：:In a double-blind investigation in 21 patients undergoing minor plastic surgery the effects of 4 mg lorazepam or a mixture of 20 mg papaveretum/400 mug hyoscine given intramuscularly as premedicants were studied. Lorazepam produced superior preoperative and post-operative anterograde amnesia, with respect to both inci...

journal_title：Current medical research and opinion

authors： Paymaster NJ

更新日期：1976-01-01 00:00:00

abstract：:Elevated serum cholesterol level is a key risk factor for cardiovascular morbidity and mortality. Cerivastatin is a highly effective lipid-lowering agent currently licensed at doses of 0.1, 0.2, 0.3 and 0.4 mg. This was a multicentre, randomised, double-blind, parallel-group study comparing the efficacy and safety of ...

journal_title：Current medical research and opinion

authors： Ose L,Luurila O,Eriksson J,Olsson A,Lithell H,Widgren B

更新日期：1999-01-01 00:00:00

abstract：:Two double-blind randomised trials are reported comparing the effectiveness of the antihistamines, clemastine and chlorpheniramine in comparable doses, in relieving the symptoms of allergic rhinitis. In the first trial, treating 58 adults seen in a general practice, both drugs were prescribed in tablet form; l mg. cle...

journal_title：Current medical research and opinion

authors： Todd G,Hopkins P,Maclay WP

更新日期：1975-01-01 00:00:00

abstract：:A clinical evaluation was carried out in 19 patients with lichen ruber planus to assess the effectiveness of 0.05% betamethasone-17,21-dipropionate ointment in the treatment of patients whose lesions had developed resistance to prolonged treatment with 0.1% betamethasone-17-valerate ointment. The new steroid ointment ...

journal_title：Current medical research and opinion

authors： Björnberg A,Hellgren L

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea syndrome (OSAS) is mostly seen in adult populations. It is known that increased levels of several inflammatory mediators play roles in OSAS and related comorbidities. Calprotectin is an inflammatory mediator that increases in some diseases such as Behçet's syndrome, bowel diseases and...

journal_title：Current medical research and opinion

authors： Torun MT,Ünver E,Yalçın Y,Kanmaz L,Seçkin E

更新日期：2018-03-01 00:00:00

abstract：INTRODUCTION:Tumor hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) expression are important factors influencing treatment response and selection in patients with metastatic breast cancer (mBC). Using the LifeLink Oncology Analyzer Database, we classified mBC patients by combined HR and HER2 st...

journal_title：Current medical research and opinion

authors： Gao S,Barber B,Schabert V,Ferrufino C

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Small cell lung cancer (SCLC) patients, who have achieved complete or partial response after chemotherapy, should be followed with prophylactic cranial irradiation (PCI). PCI for extrapulmonary small cell carcinoma (EPSCC) is not routinely recommended. The purpose of this review is to discuss all aspects of ...

journal_title：Current medical research and opinion

authors： Yazıcı O,Ozdemir NY,Sendur MA,Aksoy S,Zengin N

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To analyse the significance of 'onset of effect' on clinical outcome in the treatment of depression and the contribution of individual Montgomery-Asberg Depression Rating Scale (MADRS) items to improvements in the MADRS total score. RESEARCH DESIGN AND METHOD:All five published placebo-controlled clinical st...

journal_title：Current medical research and opinion

authors： Wade A,Friis Andersen H

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:Bariatric surgery is an effective treatment for the reduction of weight in obese patients (BMI ≥ 40 kg/m(2) or 30 kg/m(2) with ≥1 comorbidities), who are refractory to behavioral and medical therapies. This study examined the effect of the adjustable gastric band (AGB) system on changes in gastroesophageal re...

journal_title：Current medical research and opinion

authors： Woodman G,Cywes R,Billy H,Montgomery K,Cornell C,Okerson T,APEX Study Group.

更新日期：2012-04-01 00:00:00

abstract：:An open, controlled study was carried out in 30 in-patients with low arterial pressure syndrome to compare the effectiveness and tolerance of dimetophrine and midodrine in restoring blood pressure to normal levels and relieving symptoms. Patients were allocated at random to receive treatment for 15 days with either 10...

journal_title：Current medical research and opinion

authors： Marini U,Cecchi A,Venturini M

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:PREDICTIVE is a multi-national, prospective, observational study, assessing the safety and efficacy of insulin detemir in patients with diabetes. RESEARCH DESIGN AND METHODS:The European cohort includes 20,531 patients with diabetes (7420 type 1) from 11 countries. A subgroup of 4782 type 1 patients were tra...

journal_title：Current medical research and opinion

authors： Dornhorst A,Lüddeke HJ,Honka M,Ackermann RW,Meriläinen M,Gallwitz B,Sreenan S,PREDICTIVE Study Group.

更新日期：2008-02-01 00:00:00

abstract：:Type 2 diabetes mellitus is a public health problem of epidemic proportions and its prevalence is on the rise. The typical American born today has a one in three chance of developing type 2 diabetes. This diagnosis is associated with an adverse cardiovascular prognosis and is considered the risk equivalent of establis...

journal_title：Current medical research and opinion

authors： Abuissa H,Bel DS,O'keefe JH Jr

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The management of iron-deficiency anaemia in patients with non-dialysis chronic kidney disease (ND-CKD) remains controversial, particularly regarding the use of oral versus intravenous iron supplementation. METHODS:A PubMed search from 1970 to February 2009 was conducted to identify relevant research articl...

journal_title：Current medical research and opinion

authors： Macdougall IC

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:In the four SMILE (Survival of Myocardial Infarction Long-Term Evaluation) studies, early administration of zofenopril in acute myocardial infarction (AMI) showed beneficial effects as compared to placebo and other angiotensin converting enzyme inhibitors (ACEIs). This study investigated whether the concomita...

journal_title：Current medical research and opinion

authors： Borghi C,Omboni S,Reggiardo G,Bacchelli S,Degli Esposti D,Ambrosioni E,SMILE (Survival of Myocardial Infarction Long-Term Evaluation) Working Project.

更新日期：2018-10-01 00:00:00

abstract：:In an electropharmacokinetic study, the effects of lormetazepam and flunitrazepam were compared by the means of a sleep EEG and waking EEG during the following daytime. At a 1-week interval, 6 normal subjects received at random either 2 mg lormetazepam or 2 mg flunitrazepam in a double-blind, crossover fashion. Sleep ...

journal_title：Current medical research and opinion

authors： Timsit-Berthier M,de Thier D,Machowsky R,Mantanus H,Rousseau JC

更新日期：1985-01-01 00:00:00