Double-blind trials of clemastine ('Tavegil') in allergic rhinitis.

abstract：OBJECTIVE:To determine the efficacy and safety of lumiracoxib for knee osteoarthritis (OA). METHODS:This was a 13-week, multicentre, randomized, double-blind, double-dummy, placebo-controlled study. Males or females aged >/= 18 years with primary knee OA received lumiracoxib 100 mg od, lumiracoxib 100 mg od with a loa...

journal_title：Current medical research and opinion

authors： Lehmann R,Brzosko M,Kopsa P,Nischik R,Kreisse A,Thurston H,Litschig S,Sloan VS

更新日期：2005-04-01 00:00:00

abstract：:Objectives: The purpose of this study was to assess (1) the trends of and (2) the factors associated with health information technology (HIT) use among older adults in the U.S.Methods: A decade (2009-2018) of data from the U.S. National Health Interview Survey (NHIS) was used. The trends of HIT use among older adults ...

journal_title：Current medical research and opinion

authors： Hung LY,Lyons JG,Wu CH

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:Previous systematic reviews and meta-analyses of treatments in relapsing-remitting multiple sclerosis (RRMS) derived their findings from either placebo-controlled studies only or separately from head-to-head and comparative studies. The purpose of this study is to compare annualized relapse rates (ARR) of fi...

journal_title：Current medical research and opinion

authors： Roskell NS,Zimovetz EA,Rycroft CE,Eckert BJ,Tyas DA

更新日期：2012-05-01 00:00:00

abstract：:A study was carried out in 80 mild to moderately depressed patients seen in general practice to assess the relative effectiveness and tolerance of a single night-time dose compared with the usual divided daily dosage regimen of a chlordiazepoxide (5 mg)/amitriptyline (12.5 mg) combination. Patients were assigned at ra...

journal_title：Current medical research and opinion

authors： James RT,Dean BC

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and long-term safety of linagliptin added to basal insulin in Asian patients with type 2 diabetes mellitus (T2DM) inadequately controlled by basal insulin with/without oral agents. RESEARCH DESIGN AND METHODS:This was a post hoc analysis of Asian patients from a global ≥52 week study...

journal_title：Current medical research and opinion

authors： Sheu WH,Park SW,Gong Y,Pinnetti S,Bhattacharya S,Patel S,Seck T,Woerle HJ

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:Docetaxel and paclitaxel show significant clinical activity in metastatic breast cancer (MBC) and have been approved for MBC by the U.S. Food and Drug Administration, but it is still unclear whether a paclitaxel-based regimen improves outcomes over a docetaxel-based regimen in patients with MBC. We therefore...

journal_title：Current medical research and opinion

authors： Qi WX,Shen Z,Lin F,Sun YJ,Min DL,Tang LN,He AN,Yao Y

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:Tumor necrosis factor (TNF) antagonists, most frequently prescribed biologics for moderate to severe rheumatoid arthritis (RA), are subject to dose escalation. Even though different methods have been employed to estimate the timing and magnitude of dose escalation, there is no consensus on which method is op...

journal_title：Current medical research and opinion

authors： Huang X,Gu NY,Fox KM,Harrison DJ,Globe D

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Nausea with or without vomiting of pregnancy (NVP) is the most common medical condition in pregnancy. NVP, even with mild symptoms, is associated with costs to society, patients, and the health care system. OBJECTIVE:The main objective of this study was to estimate the total direct and indirect costs per wo...

journal_title：Current medical research and opinion

authors： Piwko C,Ungar WJ,Einarson TR,Wolpin J,Koren G

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To report the long-term effect of the dorzolamide/timolol (DTFC) and latanoprost/timolol (LTFC) fixed combinations on intraocular pressure (IOP) and visual field defects over time in naïve primary open-angle glaucoma (POAG) patients. STUDY DESIGN AND METHODS:Prospective, 4-year, open-label, interventional st...

journal_title：Current medical research and opinion

authors： Pajic B,Pajic-Eggspuehler B,Häfliger IO

更新日期：2010-09-01 00:00:00

abstract：:As the emergence of cardiovascular disease (CVD) is linked to modifiable lifestyle and physiological factors, it is increasingly important to concentrate on preventative strategies. For preventative measures to be beneficial it is necessary to clearly identify patients at risk--given that multiple risk factors often c...

journal_title：Current medical research and opinion

authors： De Backer G

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:In controlled clinical trials, rabeprazole effectively improves symptoms and heals oesophageal erosions in patients with gastro-oesophageal reflux disease (GORD). AIM:To examine symptom relief during week 1 of rabeprazole therapy, in addition to GORD healing, in a clinical practice setting. METHODS:In this...

journal_title：Current medical research and opinion

authors： Archimandritis AJ,Nikolopoulou V,Kouklakis G,Paraskevas E,Avgerinos A,Tsianos E,Triantafillidis JK,Hellenic Rabeprazole Study Group.

更新日期：2005-04-01 00:00:00

abstract：:A large, open, multi-centre study was carried out in general practice to evaluate the effectiveness and tolerance of a combination of 10 mg pindolol plus 5 mg clopamide, in single tablet form, in the treatment of patients with essential hypertension. Computer analysis of the records of 8989 patients who completed the ...

journal_title：Current medical research and opinion

authors： Crowder D,Cameron EG

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine whether healthy men would prefer either luteinizing hormone releasing hormone analogues (LHRHa) or non-steroidal anti-androgen therapy (NSAA) should they hypothetically develop locally advanced prostate cancer. PARTICIPANTS AND METHODS:A representative sample of 180 men...

journal_title：Current medical research and opinion

authors： Jenkins V,Fallowfield L,Edginton T,Payne H,Hamilton E

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Long-term oral corticosteroid (OCS) therapy and related adverse events are associated with a significant burden on patients and healthcare resources. METHODS:This subgroup analysis of a randomized, open-label, parallel-group study evaluated the OCS-sparing effect of omalizumab (OMA) added to optimized asthm...

journal_title：Current medical research and opinion

authors： Siergiejko Z,Świebocka E,Smith N,Peckitt C,Leo J,Peachey G,Maykut R

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of epoetin theta and epoetin beta in anaemic patients with chronic kidney disease, undergoing haemodialysis and previously on stable maintenance therapy with epoetin beta. METHODS:In this multicentre, randomised, controlled, double-blind study 270 haemodialysis patients wer...

journal_title：Current medical research and opinion

authors： Gertz B,Kohler E,Kes P,Essaian A,Bias P,Buchner A,Elsässer R

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To compare the effectiveness of 20:1 cafedrine/theodrenaline approved for use in Germany to ephedrine in the restoration of arterial blood pressure and on post-operative outcomes in patients with intra-operative arterial hypotension of any origin under standard clinical practice conditions. METHODS AND RESUL...

journal_title：Current medical research and opinion

authors： Eberhart L,Geldner G,Huljic S,Marggraf K,Keller T,Koch T,Kranke P

更新日期：2018-06-01 00:00:00

abstract：:Twenty-five acutely disturbed psychotic patients were treated in an open study with a single injection of zuclopenthixol acetate 5% in 'Viscoleo, a thin vegetable oil. Patients were assessed post-injection for 3 days using the BPRS, CGI, and a specially designed behaviour/activity scale. Doses of 50 to 150 mg proved e...

journal_title：Current medical research and opinion

authors： Chakravarti SK,Muthu A,Muthu PK,Naik P,Pinto RT

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:To investigate the role of socio-economic factors on the therapeutic effectiveness of and therapeutic adherence to the angiotensin II receptor blocker (ARB) olmesartan (OM) alone or in combination with hydrochlorothiazide in the treatment of arterial hypertension. RESEARCH DESIGN AND METHODS:In a multi-cente...

journal_title：Current medical research and opinion

authors： Scholze J,Weinstock A,Kirchner F,Limberg R,Kreutz R

更新日期：2014-10-01 00:00:00

abstract：AIMS:Disease management programs (DMP) for diabetes mellitus (DM) or coronary heart disease (CHD) address the treatment of lipid disorders. The current registry aimed to compare drug utilization, lipid lowering effects and further outcomes of outpatients at high cardiovascular risk in DMP for DM or CHD compared to pati...

journal_title：Current medical research and opinion

authors： Gitt AK,Sonntag F,Jannowitz C,Weizel A,Karmann B,Schaefer JR,Pittrow D,Hildemann SK

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to examine how lifestyle behaviors in the context of physical activity levels and screen time are associated with school absenteeism. METHODS:We analyzed 2005-2008 NHANES data of proxy interviews for 1048 children aged 6-11 years and in-person self-reports of 1117 adolescents ag...

journal_title：Current medical research and opinion

authors： Hansen AR,Pritchard T,Melnic I,Zhang J

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To assess the impact of the decision by Kela (The Social Insurance Institution) to adopt guidelines for the management of food allergies in children, developed by the Finnish Medical Society Duodecim, as the basis for reimbursing clinical nutrition preparations for the treatment of cow milk allergy (CMA) in F...

journal_title：Current medical research and opinion

authors： Guest JF,Valovirta E

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:Patients receiving levodopa for Parkinson's disease experience motor fluctuations and immobility ('off' episodes) between doses. This study assessed adjunctive Zelapar (selegiline orally disintegrating tablet (ODT)) for managing off episodes and for long-term safety. METHODS:This open-label extension evaluat...

journal_title：Current medical research and opinion

authors： Lew MF,Pahwa R,Leehey M,Bertoni J,Kricorian G,Zydis Selegiline Study Group.

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Consensus health panels, including the Joint British Societies (JBS), have established increasingly stringent cholesterol goals. However, in clinical settings, most patients do not achieve even the less stringent goals. OBJECTIVE:To provide descriptive data on the proportion of patients in the United Kingdo...

journal_title：Current medical research and opinion

authors： Rajagopalan S,Alemao E,Finch L,Yin D

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:To review clinical trial evidence supporting treatment of patients to a near-normal HbA(1c) target level and outline therapeutic strategies that optimize glycemic control. RESEARCH DESIGN AND METHODS:The current MEDLINE database and bibliographies were searched for literature relevant to diabetic complicatio...

journal_title：Current medical research and opinion

authors： Davidson JA

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Although risk factors for MI have been described in the general population, there is a lack of data on the assessment of risk factors associated with MI in venous thromboembolism (VTE) patients. OBJECTIVE:The purpose of this study was to identify risk factors associated with MI in VTE patients. PATIENTS AN...

journal_title：Current medical research and opinion

authors： Laliberté F,Nutescu EA,Lefebvre P,Rondeau-Leclaire J,Bookhart BK,LaMori JC,Damaraju CV,Schein J,Kaatz S

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:There is a general perception that research is underdeveloped in rehabilitation professions. However, a PubMed search found that the growth in publications in the rehabilitation field was twice that of the general medical field. Despite this growth, another study focusing on Europe found that the proportion ...

journal_title：Current medical research and opinion

authors： Decullier E,Tourmente B,Dessez B,Guilhot N,Witko A

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:In contrast to the trial design of acute mania studies, there is no standard design for bipolar maintenance studies. Over the past 15 years, the design of monotherapy maintenance studies in bipolar disorder has evolved significantly, but recent study designs continue to differ in important ways. SCOPE:We re...

journal_title：Current medical research and opinion

authors： Gitlin MJ,Abulseoud O,Frye MA

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) are the most commonly used pharmacological treatment for gastroesophageal reflux disease (GERD). OBJECTIVE:To examine the utilization patterns of PPIs and other GERD-related medications, satisfaction with PPI treatment and presence of GERD symptoms. PATIENTS AND METHODS:GERD p...

journal_title：Current medical research and opinion

authors： Chey WD,Mody RR,Wu EQ,Chen L,Kothari S,Persson B,Beaulieu N,Lu M

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:For the prevention of chemotherapy-induced febrile aplasia, a single injection of pegfilgrastim per cycle has the same efficacy as six to ten injections of conventional granulocyte colony-stimulating factor (G-CSF). However, there are few data on the economic impact of pegfilgrastim use, especially in the co...

journal_title：Current medical research and opinion

authors： Tan Sean P,Chouaid C,Hettler D,Baud M,Hejblum G,Tilleul P

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:GOAL (Gauging Osteoarthritis [OA] with Limbrel*), an open-label, post-marketing study was performed to determine the overall efficacy and gastrointestinal (GI) tolerability of flavocoxid, a novel, plant-based, anti-inflammatory medication, in a 'real world' clinical practice setting. To this end, the study e...

journal_title：Current medical research and opinion

authors： Pillai L,Burnett BP,Levy RM,GOAL Study Cooperative Group.

更新日期：2010-05-01 00:00:00