Preferences of healthy men for two different endocrine treatment options offered for locally advanced prostate cancer.

abstract：OBJECTIVES:Epidemiological data support an association between age-related macular degeneration (AMD) and cataract surgery that may be attributed to post-operative blue light exposure. By limiting the retina's blue light exposure, new blue-light filtering intraocular lenses (BLF IOLs) have the potential to reduce the d...

journal_title：Current medical research and opinion

authors： Reddy P,Gao X,Barnes R,Fairchild C,Boci K,Waycaster C,Pashos C

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:The clinical relevance of pro- and hyperalgesic effects of opioids is still a matter of debate. Particularly for remifentanil, an increased postoperative need for analgesics has been demonstrated suggesting opioid-induced hyperalgesia as a possible cause. The aim of the study was therefore to investigate the ...

journal_title：Current medical research and opinion

authors： Ohnesorge H,Alpes A,Baron R,Gierthmühlen J

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:Compare costs and healthcare resource utilization (HCRU) among newly-diagnosed non-valvular atrial fibrillation (NVAF) patients newly treated with dabigatran vs apixaban, rivaroxaban, or warfarin. METHODS:Newly-diagnosed adult NVAF patients initiating dabigatran, apixaban, rivaroxaban, or warfarin (index ev...

journal_title：Current medical research and opinion

authors： Gilligan AM,Franchino-Elder J,Song X,Wang C,Henriques C,Sainski-Nguyen A,Wilson K,Smith DM,Sander S

更新日期：2018-02-01 00:00:00

abstract：:Two hundred and two patients with symptoms, signs and mycological evidence of Candida vaginitis were entered in a single-blind trial comparing 6-day clotrimazole therapy with a control group receiving 6 days' nystatin therapy. Adequate data was collected on 69 clotrimazole and 72 nystatin treated patients for analysis...

journal_title：Current medical research and opinion

authors： Masterton G,Henderson J,Napier IR,Moffet M

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:The rising prevalence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) and the recent emergence of community-associated MRSA are major clinical, public health, and economic challenges. MRSA is a leading cause of nosocomial pneumonia and complicated skin and soft-tissue infections (cSSTI). Van...

journal_title：Current medical research and opinion

authors： Stein GE,Wells EM

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:The Glucose and Lipid Assessment in Diabetes (GLAD) trial examined the dose-response relationship of the dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist tesaglitazar in type 2 diabetic patients. STUDY DESIGN:GLAD was a 12-week, multicenter, international, randomized, parallel-group...

journal_title：Current medical research and opinion

authors： Goldstein BJ,Rosenstock J,Anzalone D,Tou C,Ohman KP

更新日期：2006-12-01 00:00:00

abstract：:Objective: The purpose of this study was to examine surgical and survival outcomes in the elderly (65-79 years of age) and the very elderly (≥80 years of age) who received surgery for gastric cancer.Methods: This study retrospectively reviewed the records of patients ≥65 years old who received a gastrectomy for gastri...

journal_title：Current medical research and opinion

authors： Wong JU,Tai FC,Huang CC

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that first-line treatment with atomoxetine provides superior efficacy than placebo for up to 12 weeks in improving the symptoms of Attention Deficit/Hyperactivity Disorder (ADHD). RESEARCH DESIGN AND METHODS:This double-blind, randomized, placebo-controlled, parallel clinical trial inc...

journal_title：Current medical research and opinion

authors： Montoya A,Hervas A,Cardo E,Artigas J,Mardomingo MJ,Alda JA,Gastaminza X,García-Polavieja MJ,Gilaberte I,Escobar R

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:Acute postprandial hyperglycemia (aPPHG) is often symptomatic and can be associated with behavioral changes such as impaired working memory and attention. However, there is little evidence of the impact of aPPHG on the daily lives of patients. The aim of this study was to explore the frequency and severity of...

journal_title：Current medical research and opinion

authors： Heller S,Meneghini L,Nikolajsen A,Kragh N,Lewis HB,Saretsky T,Kosmas CE,Lloyd A

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:To compare glycemic goal achievement (HbA(1c) < 7%) in type 2 diabetes patients receiving initial metformin plus pioglitazone combination therapy and initial metformin monotherapy augmented with pioglitazone in a cohort follow-up study. RESEARCH DESIGN AND METHODS:Adult patients were identified from the Inge...

journal_title：Current medical research and opinion

authors： Pandya BJ,Bron M,McCall T,Yu AP,Chen KS,Mattson ME,Wu EQ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Reducing low-density lipoprotein cholesterol (LDL-C) levels to National Cholesterol Expert Panel (NCEP) goal is recommended. However, sex-specific effects may influence benefit. METHODS AND RESULTS:In this post hoc analysis of the GREek Atorvastatin and Coronary heart disease (CHD) Evaluation [GREACE] study...

journal_title：Current medical research and opinion

authors： Athyros VG,Kakafika AI,Papageorgiou AA,Paraskevas KI,Tziomalos K,Anagnostis P,Pagourelias E,Koumaras C,Karagiannis A,Mikhailidis DP

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:Chronic obstructive pulmonary disease (COPD) is becoming a leading cause of morbidity and mortality in China. In the IMPACT trial, fluticasone furoate[FF]/umeclidinium[UMEC]/vilanterol[VI] single-inhaler triple therapy demonstrated lower rates of moderate/severe exacerbations than dual therapy with FF/VI or ...

journal_title：Current medical research and opinion

authors： Zheng J,Zhong N,Wang C,Wei LP,Zhou XD,Zhao L,Dong Yuan Y,He B,Wu B,Du X,Song J,Lipson DA

更新日期：2021-01-01 00:00:00

abstract：:Doxofylline (7-(1,3-dioxalan-2-ylmethyl) theophylline) is a novel xanthine bronchodilator which differs from theophylline in that it contains a dioxalane group in position 7. Similarly to theophylline, its mechanism of action is related to the inhibition of phosphodiesterase activities, but in contrast it appears to h...

journal_title：Current medical research and opinion

authors： Dini FL,Cogo R

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to analyze the characteristics and costs of exogenous endoscopy-related infections, pseudo-infections, and toxic reactions in the US. METHODS:A systematic review of the scientific literature published between 1966 and 2005 was conducted in Medline. Data collection was based o...

journal_title：Current medical research and opinion

authors： Seoane-Vazquez E,Rodriguez-Monguio R,Visaria J,Carlson A

更新日期：2006-10-01 00:00:00

abstract：:A study was carried out in 21 patients with Type IIb or Type IV hyperlipoproteinaemia to evaluate the effect of treatment with 600 mg bezafibrate per day over a period of 3 months. The results of the lipid parameters studied showed that there were significant reductions after 1 and 3-months' treatment, respectively, o...

journal_title：Current medical research and opinion

authors： Neuman MP,Kurlat MI,Neuman J

更新日期：1983-01-01 00:00:00

abstract：:Objectives Real-world patient outcomes data is scarce concerning the high disease burden of IBS-C. The aim of this study was to compare patient-reported symptom control, health-related quality of life (HRQoL), resource utilization, and treatment satisfaction of lubiprostone vs non-lubiprostone treatment for irritable ...

journal_title：Current medical research and opinion

authors： Solem CT,Patel H,Mehta S,Mody R,Macahilig C,Gao X

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:To report the long-term effect of the dorzolamide/timolol (DTFC) and latanoprost/timolol (LTFC) fixed combinations on intraocular pressure (IOP) and visual field defects over time in naïve primary open-angle glaucoma (POAG) patients. STUDY DESIGN AND METHODS:Prospective, 4-year, open-label, interventional st...

journal_title：Current medical research and opinion

authors： Pajic B,Pajic-Eggspuehler B,Häfliger IO

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:As results from an increasing number of clinical trials with disease-modifying drugs (DMDs) in multiple sclerosis (MS) become available, the challenge for the treating neurologist is how to decide on the appropriate therapy for an individual patient. OBJECTIVE:An International Working Group for Treatment Op...

journal_title：Current medical research and opinion

authors： Goodin DS,Biermann LD,Bohlega S,Boiko A,Chofflon M,Gebeily S,Gouider R,Havrdova E,Jakab G,Karabudak R,Karussis D,Miller A,Pakdaman H,Selmaj K,Sharief M,International Working Group for Treatment Optimization in MS.

更新日期：2007-11-01 00:00:00

abstract：:Twenty-seven patients with tennis elbow were treated with triamcinolone acetonide (40 mg/ml) injected locally into the tender area without local anaesthetic. Reduction of pain or complete relief was achieved in 1 to 72 hours, although in 9 cases exacerbation of pain occurred before relief was given. The recurrence rat...

journal_title：Current medical research and opinion

authors： Nevelös AB

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:To evaluate intraocular pressure (IOP)-lowering efficacy, tolerability, and safety of the fixed combination of bimatoprost 0.03% and timolol 0.5% (Ganfort) among German patients. METHODS:Multicenter, observational, open-label study of patients with primary open angle glaucoma or ocular hypertension (n = 606)...

journal_title：Current medical research and opinion

authors： Feuerhake C,Buchholz P,Kimmich F

更新日期：2009-04-01 00:00:00

abstract：:A single-blind, between-patient comparative study was carried out in general practice to assess the effectiveness of antacid plus antispasmodic combination tablets (240 mg dried aluminium hydroxide B.P., 144 mg magnesium hydroxide B.P.C., and 5 mg dicyclomine hydrochloride B.P.) and aluminium hydroxide B.P. tablets (5...

journal_title：Current medical research and opinion

authors： Kagan G,Rose R

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:Neurosurgery often requires skull immobilization with a Mayfield clamp, which often causes brief intense nociceptive stimulation, hypertension and tachycardia. Blunting this response may help prevent increased intracranial pressure, cerebral aneurysm or vascular malformation rupture, and/or myocardial stress....

journal_title：Current medical research and opinion

authors： Berger M,Philips-Bute B,Guercio J,Hopkins TJ,James ML,Borel CO,Warner DS,McDonagh DL

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:To compare the efficacy and safety of the concomitant administration of travoprost 0.004% once daily and brinzolamide 0.1% twice daily with those of a fixed combination of latanoprost 0.005%/timolol 0.5% once daily. RESEARCH, DESIGN AND METHODS:Forty-four patients with primary open-angle glaucoma or ocular hyp...

journal_title：Current medical research and opinion

authors： Martinez-de-la-Casa JM,Castillo A,Garcia-Feijoo J,Mendez-Hernandez C,Fernandez-Vidal A,Garcia-Sanchez J

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:The dopamine agonist rotigotine has shown efficacy and safety for the treatment of early and advanced Parkinson's disease (PD) in controlled clinical trials. This observational study evaluated rotigotine administration in combination with other antiparkinsonian medication in routine clinical practice. METHOD...

journal_title：Current medical research and opinion

authors： Ceballos-Baumann A,Häck HJ

更新日期：2011-10-01 00:00:00

abstract：:An open, multi-centre trial was carried out to assess the efficacy and tolerance of acemetacin in the treatment of patients suffering from various rheumatic diseases. The patients were treated by general practitioners for a maximum period of 6 weeks with a daily dose of 60 mg acemetacin 3-times daily. Assessments were...

journal_title：Current medical research and opinion

authors： Rechziegler H,Zündorf P

更新日期：1985-01-01 00:00:00

abstract：:Two clinical trials were carried out in order to study adrenal suppression in 6 patients with psoriatic erythroderma and in 28 patients with psoriasis treated with topical glucocorticosteroids. Betamethasone-17-valerate (0.1%), betamethasone-17,21-dipropionate (0.05%) and budesonide (0.025%) ointments were studied in ...

journal_title：Current medical research and opinion

authors： Salde L,Lassus A

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVES:This study proposed a conception of individualized chemotherapy based on organ selectivity of drug distribution by retrospectively comparing the effect of vinorelbine and capecitabine in patients with metastatic breast cancer. METHODS:Between January 2002 and December 2009, 133 patients with lung metastasis...

journal_title：Current medical research and opinion

authors： Liu XH,Man YN,Cao R,Liu C,Wu XZ

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To investigate if combined intraocular pressure (IOP)-lowering medication with travoprost/timolol fixed combination and a carbonic anhydrase inhibitor, brinzolamide, is superior to both travoprost monotherapy and travoprost/timolol fixed-combination therapy in primary open-angle glaucoma and ocular hypertensi...

journal_title：Current medical research and opinion

authors： Holló G,Kóthy P

更新日期：2008-06-01 00:00:00

abstract：:Adherence to allergen immunotherapy (AIT) is crucial for its efficacy. Subcutaneous AIT requires monthly visits (or more extended in the case of venom immunotherapy), while sublingual AIT is performed with a daily intake of allergen drops. Non-adherence to an AIT schedule and premature discontinuation are common probl...

journal_title：Current medical research and opinion

authors： Pitsios C,Dietis N

更新日期：2019-06-01 00:00:00

abstract：:Venous thromboembolism (VTE) is a major cause of morbidity and mortality and is associated with substantial healthcare costs. Identification of patients at risk of developing VTE enables appropriate thromboprophylaxis to be implemented. Although no predisposing risk factors can be identified in many patients in whom V...

journal_title：Current medical research and opinion

authors： Shirvanian S,Tapson VF

更新日期：2015-12-01 00:00:00